Nerolidol

Nerolidol is a lipid of Prenol Lipids (PR) class. Nerolidol is associated with abnormalities such as Hyperostosis, Diffuse Idiopathic Skeletal, Corn of toe, Infection, Leishmaniasis and Leishmaniasis, Cutaneous. The involved functions are known as Protein Biosynthesis, Anabolism, Signal, volatile substances and terpene biosynthetic process. Nerolidol often locates in Protoplasm, Plastids, Cytoplasmic matrix, Body tissue and Mitochondria. The associated genes with Nerolidol are Genome, Genes, Plant, Homologous Gene, Recombinant Proteins and monoterpene synthase. The related lipids are Pinene, prenol and Sterols.

Cross Reference

Introduction

To understand associated biological information of Nerolidol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Nerolidol?

Nerolidol is suspected in Plasmodium falciparum infection, Infection, Corn of toe, Leishmaniasis, Leishmaniasis, Cutaneous, Exanthema and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Nerolidol

MeSH term MeSH ID Detail
Stomach Ulcer D013276 75 associated lipids
Dermatomycoses D003881 17 associated lipids
Leishmaniasis D007896 19 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with Nerolidol

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Nerolidol through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Nerolidol?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Nerolidol?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Nerolidol?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Nerolidol?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Nerolidol?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Nerolidol

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Brehm-Stecher BF and Johnson EA Sensitization of Staphylococcus aureus and Escherichia coli to antibiotics by the sesquiterpenoids nerolidol, farnesol, bisabolol, and apritone. 2003 Antimicrob. Agents Chemother. pmid:14506058
da Silva MF et al. In Vitro Antimalarial Activity of Different Inhibitors of the Plasmodial Isoprenoid Synthesis Pathway. 2015 Antimicrob. Agents Chemother. pmid:26055383
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Madyastha KM and Gururaja TL A new pathway for the degradation of a sesquiterpene alcohol, nerolidol by Alcaligenes eutrophus. 1993 Biochem. Biophys. Res. Commun. pmid:8503916
Tonhosolo R et al. Identification, molecular cloning and functional characterization of an octaprenyl pyrophosphate synthase in intra-erythrocytic stages of Plasmodium falciparum. 2005 Biochem. J. pmid:15984931
Lee SJ et al. Antifungal effect of eugenol and nerolidol against Microsporum gypseum in a guinea pig model. 2007 Biol. Pharm. Bull. pmid:17202684
Kiem PV et al. Chemical constituents of the rhizomes of Hedychium coronarium and their inhibitory effect on the pro-inflammatory cytokines production LPS-stimulated in bone marrow-derived dendritic cells. 2011 Bioorg. Med. Chem. Lett. pmid:22071304
Hrdlicka PJ et al. Characterization of nerolidol biotransformation based on indirect on-line estimation of biomass concentration and physiological state in batch cultures of Aspergillus niger. 2004 Jan-Feb Biotechnol. Prog. pmid:14763865
Steyer D et al. QTL mapping of the production of wine aroma compounds by yeast. 2012 BMC Genomics pmid:23110365
Javed H et al. Neuroprotective effect of nerolidol against neuroinflammation and oxidative stress induced by rotenone. 2016 BMC Neurosci pmid:27549180
Wattenberg LW Inhibition of azoxymethane-induced neoplasia of the large bowel by 3-hydroxy-3,7,11-trimethyl-1,6,10-dodecatriene (nerolidol). 1991 Carcinogenesis pmid:1988176
Cristofari G et al. Chemical diversity of essential oils from Asteriscus graveolens (Forssk.) less.: identification of cis-8-Acetoxychrysanthenyl acetate as a new natural component. 2012 Chem. Biodivers. pmid:22492491
Utsumi S et al. Effect of Nerolidol and/or Levulinic Acid on the Thermotropic Behavior of Lipid Lamellar Structures in the Stratum Corneum. 2016 Chem. Pharm. Bull. pmid:27904078
BektaÅŸ A et al. Design and evaluation of polysaccharide-based transdermal films for the controlled delivery of nifedipine. 2014 Chem. Pharm. Bull. pmid:24492584
Nakano C et al. Identification and characterization of the linalool/nerolidol synthase from Streptomyces clavuligerus. 2011 Chembiochem pmid:21910204
Baer P et al. Hedycaryol synthase in complex with nerolidol reveals terpene cyclase mechanism. 2014 Chembiochem pmid:24399794
Navarro-Moll MC et al. In vitro and in vivo activity of three sesquiterpenes against L(3) larvae of Anisakis type I. 2011 Exp. Parasitol. pmid:20932829
Tamogami S et al. Conversion of airborne nerolidol to DMNT emission requires additional signals in Achyranthes bidentata. 2011 FEBS Lett. pmid:21510937
de Macedo CS et al. Characterization of the isoprenoid chain of coenzyme Q in Plasmodium falciparum. 2002 FEMS Microbiol. Lett. pmid:11886744