Nerolidol

Nerolidol is a lipid of Prenol Lipids (PR) class. Nerolidol is associated with abnormalities such as Hyperostosis, Diffuse Idiopathic Skeletal, Corn of toe, Infection, Leishmaniasis and Leishmaniasis, Cutaneous. The involved functions are known as Protein Biosynthesis, Anabolism, Signal, volatile substances and terpene biosynthetic process. Nerolidol often locates in Protoplasm, Plastids, Cytoplasmic matrix, Body tissue and Mitochondria. The associated genes with Nerolidol are Genome, Genes, Plant, Homologous Gene, Recombinant Proteins and monoterpene synthase. The related lipids are Pinene, prenol and Sterols.

Cross Reference

Introduction

To understand associated biological information of Nerolidol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Nerolidol?

Nerolidol is suspected in Plasmodium falciparum infection, Infection, Corn of toe, Leishmaniasis, Leishmaniasis, Cutaneous, Exanthema and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Nerolidol

MeSH term MeSH ID Detail
Stomach Ulcer D013276 75 associated lipids
Dermatomycoses D003881 17 associated lipids
Leishmaniasis D007896 19 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with Nerolidol

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Nerolidol through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Nerolidol?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Nerolidol?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Nerolidol?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Nerolidol?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Nerolidol?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Nerolidol

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Authors Title Published Journal PubMed Link
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Camargos HS et al. Terpenes increase the lipid dynamics in the Leishmania plasma membrane at concentrations similar to their IC50 values. 2014 PLoS ONE pmid:25101672
Baer P et al. Hedycaryol synthase in complex with nerolidol reveals terpene cyclase mechanism. 2014 Chembiochem pmid:24399794
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Ma C et al. Determination of nerolidol in teas using headspace solid phase microextraction-gas chromatography. 2014 Food Chem pmid:24444938
Le Thanh C and Chauhan KR Simple and short synthesis of trans-(R)-nerolidol, a pheromone component of fruit spotting bug. 2014 Nat Prod Commun pmid:24689198
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Silva MP et al. Antischistosomal activity of the terpene nerolidol. 2014 Molecules pmid:24662089
Zhu BQ et al. Identification of a plastid-localized bifunctional nerolidol/linalool synthase in relation to linalool biosynthesis in young grape berries. 2014 Int J Mol Sci pmid:25470020
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Houshyani B et al. Three-step pathway engineering results in more incidence rate and higher emission of nerolidol and improved attraction of Diadegma semiclausum. 2013 Metab. Eng. pmid:23154132
Sakhanokho HF et al. Chemical composition, antifungal and insecticidal activities of Hedychium essential oils. 2013 Molecules pmid:23579997
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Nogueira Neto JD et al. Antioxidant effects of nerolidol in mice hippocampus after open field test. 2013 Neurochem. Res. pmid:23765368
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Wang SY et al. Specific involvement of two amino acid residues in cis-nerolidol binding to odorant-binding protein 5 AlinOBP5 in the alfalfa plant bug, Adelphocoris lineolatus (Goeze). 2013 Insect Mol. Biol. pmid:23294484
Ferreira FM et al. Nerolidol effects on mitochondrial and cellular energetics. 2012 Toxicol In Vitro pmid:22138475
Green SA et al. Identification, functional characterization, and regulation of the enzyme responsible for floral (E)-nerolidol biosynthesis in kiwifruit (Actinidia chinensis). 2012 J. Exp. Bot. pmid:22162874
Chen F et al. Transdermal behaviors comparisons among Evodia rutaecarpa extracts with different purity of evodiamine and rutaecarpine and the effect of topical formulation in vivo. 2012 Fitoterapia pmid:22565145
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Di Campli E et al. Activity of tea tree oil and nerolidol alone or in combination against Pediculus capitis (head lice) and its eggs. 2012 Parasitol. Res. pmid:22847279
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Navarro-Moll MC et al. In vitro and in vivo activity of three sesquiterpenes against L(3) larvae of Anisakis type I. 2011 Exp. Parasitol. pmid:20932829
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Tamogami S et al. Conversion of airborne nerolidol to DMNT emission requires additional signals in Achyranthes bidentata. 2011 FEBS Lett. pmid:21510937
Kiem PV et al. Chemical constituents of the rhizomes of Hedychium coronarium and their inhibitory effect on the pro-inflammatory cytokines production LPS-stimulated in bone marrow-derived dendritic cells. 2011 Bioorg. Med. Chem. Lett. pmid:22071304
Nakano C et al. Identification and characterization of the linalool/nerolidol synthase from Streptomyces clavuligerus. 2011 Chembiochem pmid:21910204
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