Nerolidol

Nerolidol is a lipid of Prenol Lipids (PR) class. Nerolidol is associated with abnormalities such as Hyperostosis, Diffuse Idiopathic Skeletal, Corn of toe, Infection, Leishmaniasis and Leishmaniasis, Cutaneous. The involved functions are known as Protein Biosynthesis, Anabolism, Signal, volatile substances and terpene biosynthetic process. Nerolidol often locates in Protoplasm, Plastids, Cytoplasmic matrix, Body tissue and Mitochondria. The associated genes with Nerolidol are Genome, Genes, Plant, Homologous Gene, Recombinant Proteins and monoterpene synthase. The related lipids are Pinene, prenol and Sterols.

Cross Reference

Introduction

To understand associated biological information of Nerolidol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Nerolidol?

Nerolidol is suspected in Plasmodium falciparum infection, Infection, Corn of toe, Leishmaniasis, Leishmaniasis, Cutaneous, Exanthema and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Nerolidol

MeSH term MeSH ID Detail
Stomach Ulcer D013276 75 associated lipids
Dermatomycoses D003881 17 associated lipids
Leishmaniasis D007896 19 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with Nerolidol

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Nerolidol through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Nerolidol?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Nerolidol?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Nerolidol?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Nerolidol?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Nerolidol?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Nerolidol

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Authors Title Published Journal PubMed Link
Padovan A et al. The molecular basis of host plant selection in Melaleuca quinquenervia by a successful biological control agent. 2010 Phytochemistry pmid:20554297
Triana J et al. A chemotaxonomic study of endemic species of genus Tanacetum from the Canary Islands. 2013 Phytochemistry pmid:23714725
Sylvestre M et al. Composition and cytotoxic activity of the leaf essential oil of Comptonia peregrina (L.) Coulter. 2007 Phytother Res pmid:17326040
Aharoni A et al. Terpenoid metabolism in wild-type and transgenic Arabidopsis plants. 2003 Plant Cell pmid:14630967
Aharoni A et al. Gain and loss of fruit flavor compounds produced by wild and cultivated strawberry species. 2004 Plant Cell pmid:15522848
Richter A et al. Characterization of Biosynthetic Pathways for the Production of the Volatile Homoterpenes DMNT and TMTT in Zea mays. 2016 Plant Cell pmid:27662898
Nagegowda DA et al. Two nearly identical terpene synthases catalyze the formation of nerolidol and linalool in snapdragon flowers. 2008 Plant J. pmid:18363779
Bouwmeester HJ et al. Spider mite-induced (3S)-(E)-nerolidol synthase activity in cucumber and lima bean. The first dedicated step in acyclic C11-homoterpene biosynthesis. 1999 Plant Physiol. pmid:10482672
Schnee C et al. The maize gene terpene synthase 1 encodes a sesquiterpene synthase catalyzing the formation of (E)-beta-farnesene, (E)-nerolidol, and (E,E)-farnesol after herbivore damage. 2002 Plant Physiol. pmid:12481088
Kant MR et al. Differential timing of spider mite-induced direct and indirect defenses in tomato plants. 2004 Plant Physiol. pmid:15122016
Vucetic A et al. Volatile interaction between undamaged plants affects tritrophic interactions through changed plant volatile emission. 2014 Plant Signal Behav pmid:25763628
Degenhardt J and Gershenzon J Demonstration and characterization of (E)-nerolidol synthase from maize: a herbivore-inducible terpene synthase participating in (3E)-4,8-dimethyl-1,3,7-nonatriene biosynthesis. 2000 Planta pmid:10805454
Martin DM et al. Biosynthesis of wine aroma: transcript profiles of hydroxymethylbutenyl diphosphate reductase, geranyl diphosphate synthase, and linalool/nerolidol synthase parallel monoterpenol glycoside accumulation in Gewürztraminer grapes. 2012 Planta pmid:22824963
Chinou IB et al. Chemical and biological studies on two Helichrysum species of Greek origin. 1996 Planta Med. pmid:8792676
Markovic D et al. Plant Responses to Brief Touching: A Mechanism for Early Neighbour Detection? 2016 PLoS ONE pmid:27828995
Camargos HS et al. Terpenes increase the lipid dynamics in the Leishmania plasma membrane at concentrations similar to their IC50 values. 2014 PLoS ONE pmid:25101672
Kappers IF et al. Genetic engineering of terpenoid metabolism attracts bodyguards to Arabidopsis. 2005 Science pmid:16179482
Pennisi E Plant science. New gene boosts plant's defenses against pests. 2005 Science pmid:16179441
Ferreira FM et al. Nerolidol effects on mitochondrial and cellular energetics. 2012 Toxicol In Vitro pmid:22138475
Klopell FC et al. Nerolidol, an antiulcer constituent from the essential oil of Baccharis dracunculifolia DC (Asteraceae). 2007 Jul-Aug Z. Naturforsch., C, J. Biosci. pmid:17913068
Song WF et al. [Analyze on chemical compositions of Dalbergia odorifera essential oils extracted by CO2-supercritical-fluid-extraction and steam distillation extraction]. 2011 Zhong Yao Cai pmid:22506398
Lu Q et al. [Simultaneous determination of water-soluble components and nerolidol in xiangdan injection by high performance liquid chromatography with column switching]. 2008 Zhongguo Zhong Yao Za Zhi pmid:19260309
Hu M et al. [Determination of nerolidol in volatile oil of Dalbergia odorifera by GC]. 2005 Zhongguo Zhong Yao Za Zhi pmid:16124604