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2010 |
Mol. Microbiol. |
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2010 |
Cutan Ocul Toxicol |
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Salirasib inhibits the growth of hepatocarcinoma cell lines in vitro and tumor growth in vivo through ras and mTOR inhibition. |
2010 |
Mol. Cancer |
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2010 |
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J Chromatogr A |
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2010 |
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2010 |
Molecules |
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2010 |
J Biomed Mater Res A |
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Phase 1 first-in-human clinical study of S-trans,trans-farnesylthiosalicylic acid (salirasib) in patients with solid tumors. |
2010 |
Cancer Chemother. Pharmacol. |
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Molecular mechanisms involved in farnesol-induced apoptosis. |
2010 |
Cancer Lett. |
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Immunotoxicity activity of the major essential oil of Filipendula glaberrima against Aedes aegypti L. |
2010 |
Immunopharmacol Immunotoxicol |
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2010 |
Oncogene |
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2010 |
Antimicrob. Agents Chemother. |
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Ras inhibits endoplasmic reticulum stress in human cancer cells with amplified Myc. |
2010 |
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2010 |
Am. J. Physiol., Cell Physiol. |
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Synthesis and evaluation of nitric oxide-releasing derivatives of farnesylthiosalicylic acid as anti-tumor agents. |
2010 |
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In vitro pro- and anti-inflammatory responses to viable Candida albicans yeasts by a murine macrophage cell line. |
2010 |
Med. Mycol. |
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Proto-oncogenic H-Ras, K-Ras, and N-Ras are involved in muscle differentiation via phosphatidylinositol 3-kinase. |
2010 |
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J. Chem. Ecol. |
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Ultra high performance liquid chromatography tandem mass spectrometry analysis of quorum-sensing molecules of Candida albicans. |
2010 |
J Pharm Biomed Anal |
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Candida albicans cell wall components and farnesol stimulate the expression of both inflammatory and regulatory cytokines in the murine RAW264.7 macrophage cell line. |
2010 |
FEMS Immunol. Med. Microbiol. |
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The roles played by Aspergillus nidulans apoptosis-inducing factor (AIF)-like mitochondrial oxidoreductase (AifA) and NADH-ubiquinone oxidoreductases (NdeA-B and NdiA) in farnesol resistance. |
2010 |
Fungal Genet. Biol. |
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Candida albicans-produced farnesol stimulates Pseudomonas quinolone signal production in LasR-defective Pseudomonas aeruginosa strains. |
2010 |
Microbiology (Reading, Engl.) |
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The quorum-sensing molecule E,E-farnesol--its variable secretion and its impact on the growth and metabolism of Candida species. |
2010 |
Yeast |
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Salirasib in the treatment of pancreatic cancer. |
2010 |
Future Oncol |
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Farnesol induces hydrogen peroxide resistance in Candida albicans yeast by inhibiting the Ras-cyclic AMP signaling pathway. |
2010 |
Eukaryotic Cell |
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2010 |
Chem. Biol. Interact. |
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Mevalonate pathway intermediates downregulate zoledronic acid-induced isopentenyl pyrophosphate and ATP analog formation in human breast cancer cells. |
2010 |
Biochem. Pharmacol. |
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In vivo and in vitro skin absorption of lipophilic compounds, dibutyl phthalate, farnesol and geraniol in the hairless guinea pig. |
2010 |
Food Chem. Toxicol. |
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Chromene-3-carboxamide derivatives discovered from virtual screening as potent inhibitors of the tumour maker, AKR1B10. |
2010 |
Bioorg. Med. Chem. |
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Farnesol misplaces tip-localized Rho proteins and inhibits cell wall integrity signalling in Aspergillus fumigatus. |
2010 |
Mol. Microbiol. |
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The Ras antagonist farnesylthiosalicylic acid ameliorates experimental myocarditis in the rat. |
2010 Mar-Apr |
Cardiovasc. Pathol. |
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Linking quorum sensing regulation and biofilm formation by Candida albicans. |
2011 |
Methods Mol. Biol. |
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Antimicrobial traits of tea- and cranberry-derived polyphenols against Streptococcus mutans. |
2011 |
Caries Res. |
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Inhibitory effect of farnesylthiosalicylic acid on mediators release by mast cells: preferential inhibition of prostaglandin D(2) and tumor necrosis factor-α release. |
2011 |
Inflammation |
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In vitro and in vivo activity of three sesquiterpenes against L(3) larvae of Anisakis type I. |
2011 |
Exp. Parasitol. |
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Roles for farnesol and ABA in Arabidopsis flower development. |
2011 |
Plant Signal Behav |
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Ras inhibition induces insulin sensitivity and glucose uptake. |
2011 |
PLoS ONE |
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The quorum-sensing molecule farnesol is a modulator of drug efflux mediated by ABC multidrug transporters and synergizes with drugs in Candida albicans. |
2011 |
Antimicrob. Agents Chemother. |
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A phase II trial of Salirasib in patients with lung adenocarcinomas with KRAS mutations. |
2011 |
J Thorac Oncol |
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Inhibition of contact sensitivity by farnesylthiosalicylic acid-amide, a potential Rap1 inhibitor. |
2011 |
J. Invest. Dermatol. |
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