| MeSH term | MeSH ID | Detail |
|---|---|---|
| Adenocarcinoma | D000230 | 166 associated lipids |
| Lupus Erythematosus, Systemic | D008180 | 43 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Osteosarcoma | D012516 | 50 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Thyroid Neoplasms | D013964 | 33 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Fibrosis | D005355 | 23 associated lipids |
| Leukemia, Myeloid, Acute | D015470 | 19 associated lipids |
| Hypergammaglobulinemia | D006942 | 9 associated lipids |
| Glioblastoma | D005909 | 27 associated lipids |
| Nephritis | D009393 | 19 associated lipids |
| HIV Infections | D015658 | 20 associated lipids |
| Neurilemmoma | D009442 | 10 associated lipids |
(e,z)-farnesol
(e,z)-farnesol is a lipid of Prenol Lipids (PR) class.
Cross Reference
There are no associated biomedical information in the current reference collection.
Current reference collection contains 3613 references associated with (e,z)-farnesol in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.
Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.
Here are additional resources we collected from PubChem and MeSH for (e,z)-farnesol
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with (e,z)-farnesol
PubChem Biomolecular Interactions and Pathways
All references with (e,z)-farnesol
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Rung E et al. | Depletion of substrates for protein prenylation increases apoptosis in human periovulatory granulosa cells. | 2006 | Mol. Reprod. Dev. | pmid:16868926 |
| Jin J et al. | Farnesol, a potential efflux pump inhibitor in Mycobacterium smegmatis. | 2010 | Molecules | pmid:21042264 |
| Å piÄáková A et al. | Nerolidol and Farnesol Inhibit Some Cytochrome P450 Activities but Did Not Affect Other Xenobiotic-Metabolizing Enzymes in Rat and Human Hepatic Subcellular Fractions. | 2017 | Molecules | pmid:28338641 |
| Togashi N et al. | Effects of two terpene alcohols on the antibacterial activity and the mode of action of farnesol against Staphylococcus aureus. | 2008 | Molecules | pmid:19078849 |
| Gonçalves O et al. | Evaluation of the mutagenicity of sesquiterpenic compounds and their influence on the susceptibility towards antibiotics of two clinically relevant bacterial strains. | 2011 | Mutat. Res. | pmid:21453784 |
| Cotoras M et al. | Farnesol induces apoptosis-like phenotype in the phytopathogenic fungus Botrytis cinerea. | 2013 Jan-Feb | Mycologia | pmid:22962358 |
| Lichtor PA and Miller SJ | Combinatorial evolution of site- and enantioselective catalysts for polyene epoxidation. | 2012 | Nat Chem | pmid:23174978 |
| Farag MA and Al-Mahdy DA | Comparative study of the chemical composition and biological activities of Magnolia grandiflora and Magnolia virginiana flower essential oils. | 2013 | Nat. Prod. Res. | pmid:22690913 |
| Fukada Y et al. | Farnesylated gamma-subunit of photoreceptor G protein indispensable for GTP-binding. | 1990 | Nature | pmid:2385292 |
| Lowy DR and Willumsen BM | Protein modification: new clue to Ras lipid glue. | 1989 | Nature | pmid:2677741 |
| Goldstein JL and Brown MS | Regulation of the mevalonate pathway. | 1990 | Nature | pmid:1967820 |
| Scheper MA et al. | Farnesol, a fungal quorum-sensing molecule triggers apoptosis in human oral squamous carcinoma cells. | 2008 | Neoplasia | pmid:18714396 |
| Grossman R et al. | Increase in peripheral benzodiazepine receptors and loss of glutamate NMDA receptors in a mouse model of closed head injury: a quantitative autoradiographic study. | 2003 | Neuroimage | pmid:14683703 |
| Binda C et al. | Structure of the human mitochondrial monoamine oxidase B: new chemical implications for neuroprotectant drug design. | 2006 | Neurology | pmid:17030739 |
| Mans RA et al. | Simvastatin-mediated enhancement of long-term potentiation is driven by farnesyl-pyrophosphate depletion and inhibition of farnesylation. | 2012 | Neuroscience | pmid:22192838 |
| Cho T et al. | [Farnesol as a quorum-sensing molecule in Candida albicans]. | 2008 | Nihon Ishinkin Gakkai Zasshi | pmid:19001754 |
| Cho T et al. | Transcriptional changes in Candida albicans Genes by both farnesol and high cell density at an early stage of morphogenesis in N-acetyl-D-glucosamine medium. | 2007 | Nihon Ishinkin Gakkai Zasshi | pmid:17975531 |
| Jones S et al. | β-ionone induces cell cycle arrest and apoptosis in human prostate tumor cells. | 2013 | Nutr Cancer | pmid:23659452 |
| Hanker AB et al. | Differential requirement of CAAX-mediated posttranslational processing for Rheb localization and signaling. | 2010 | Oncogene | pmid:19838215 |
| Weisz B et al. | A new functional Ras antagonist inhibits human pancreatic tumor growth in nude mice. | 1999 | Oncogene | pmid:10353601 |
| Ghosh PM et al. | Role of RhoA activation in the growth and morphology of a murine prostate tumor cell line. | 1999 | Oncogene | pmid:10435593 |
| Shack S et al. | Activation of the cholesterol pathway and Ras maturation in response to stress. | 1999 | Oncogene | pmid:10557091 |
| Aizman E et al. | Ras inhibition by FTS attenuates brain tumor growth in mice by direct antitumor activity and enhanced reactivity of cytotoxic lymphocytes. | 2012 | Oncotarget | pmid:22323550 |
| Mashiach-Farkash E et al. | Computer-based identification of a novel LIMK1/2 inhibitor that synergizes with salirasib to destabilize the actin cytoskeleton. | 2012 | Oncotarget | pmid:22776759 |
| Schmukler E et al. | Ras inhibition enhances autophagy, which partially protects cells from death. | 2013 | Oncotarget | pmid:23370967 |
| Barkan B et al. | Ras inhibition boosts galectin-7 at the expense of galectin-1 to sensitize cells to apoptosis. | 2013 | Oncotarget | pmid:23530091 |
| Faigenbaum R et al. | Growth of poorly differentiated endometrial carcinoma is inhibited by combined action of medroxyprogesterone acetate and the Ras inhibitor Salirasib. | 2013 | Oncotarget | pmid:23530112 |
| Cheng HL et al. | Zoledronate blocks geranylgeranylation not farnesylation to suppress human osteosarcoma U2OS cells metastasis by EMT via Rho A activation and FAK-inhibited JNK and p38 pathways. | 2016 | Oncotarget | pmid:26848867 |
| Hameiri-Grossman M et al. | The association between let-7, RAS and HIF-1α in Ewing Sarcoma tumor growth. | 2015 | Oncotarget | pmid:26393682 |
| Goldshmit Y et al. | Interfering with the interaction between ErbB1, nucleolin and Ras as a potential treatment for glioblastoma. | 2014 | Oncotarget | pmid:25261371 |
| Schmukler E et al. | Chloroquine synergizes with FTS to enhance cell growth inhibition and cell death. | 2014 | Oncotarget | pmid:24368422 |
| Koo H et al. | Effects of apigenin and tt-farnesol on glucosyltransferase activity, biofilm viability and caries development in rats. | 2002 | Oral Microbiol. Immunol. | pmid:12485324 |
| Jin Y and Qiu FG | A convergent stereocontrolled total synthesis of (-)-terpestacin. | 2012 | Org. Biomol. Chem. | pmid:22710980 |
| Toró A et al. | Transannular Diels-Alder studies on the asymmetric total synthesis of chatancin: the pyranophane approach. | 2000 | Org. Lett. | pmid:10964353 |
| Yu JS et al. | Synthesis of farnesol isomers via a modified Wittig procedure. | 2005 | Org. Lett. | pmid:16235893 |
| Rudi A et al. | Likonides A and B: new ansa farnesyl quinols from the marine sponge Hyatella sp. | 2004 | Org. Lett. | pmid:15496087 |
| Pammi M et al. | Farnesol decreases biofilms of Staphylococcus epidermidis and exhibits synergy with nafcillin and vancomycin. | 2011 | Pediatr. Res. | pmid:21857375 |
| Marcuzzi A et al. | Natural isoprenoids are able to reduce inflammation in a mouse model of mevalonate kinase deficiency. | 2008 | Pediatr. Res. | pmid:18391837 |
| Teal PE | Effects of allatotropin and allatostatin on in vitro production of juvenile hormones by the corpora allata of virgin females of the moths of Heliothis virescens and Manduca sexta. | 2002 | Peptides | pmid:11897385 |
| Tóth M et al. | Identification of pheromones and optimization of bait composition for click beetle pests (Coleoptera: Elateridae) in Central and Western Europe. | 2003 | Pest Manag. Sci. | pmid:12701702 |
| Tojo K et al. | Diffusion and metabolism of prednisolone farnesylate in viable skin of the hairless mouse. | 1994 | Pharm. Res. | pmid:8008705 |
| Zhang W et al. | Vaginal Microbicide Film Combinations of Two Reverse Transcriptase Inhibitors, EFdA and CSIC, for the Prevention of HIV-1 Sexual Transmission. | 2015 | Pharm. Res. | pmid:25794967 |
| Cetin A et al. | Angiotensin II-induced MAPK phosphorylation mediated by Ras and/or phospholipase C-dependent phosphorylations but not by protein kinase C phosphorylation in cultured rat vascular smooth muscle cells. | 2007 | Pharmacology | pmid:17135774 |
| Kuete V and Efferth T | Molecular determinants of cancer cell sensitivity and resistance towards the sesquiterpene farnesol. | 2013 | Pharmazie | pmid:23923645 |
| Cheng AX et al. | The rice (E)-beta-caryophyllene synthase (OsTPS3) accounts for the major inducible volatile sesquiterpenes. | 2007 | Phytochemistry | pmid:17524436 |
| Nah J et al. | Partial characterization of farnesyl and geranylgeranyl diphosphatases induced in rice seedlings by UV-C irradiation. | 2001 | Plant Cell Physiol. | pmid:11522913 |
| Fitzpatrick AH et al. | Farnesol kinase is involved in farnesol metabolism, ABA signaling and flower development in Arabidopsis. | 2011 | Plant J. | pmid:21395888 |
| Crowell DN et al. | Arabidopsis thaliana plants possess a specific farnesylcysteine lyase that is involved in detoxification and recycling of farnesylcysteine. | 2007 | Plant J. | pmid:17425716 |
| Bhandari J et al. | Identification of a novel abscisic acid-regulated farnesol dehydrogenase from Arabidopsis. | 2010 | Plant Physiol. | pmid:20807998 |
| Schnee C et al. | The maize gene terpene synthase 1 encodes a sesquiterpene synthase catalyzing the formation of (E)-beta-farnesene, (E)-nerolidol, and (E,E)-farnesol after herbivore damage. | 2002 | Plant Physiol. | pmid:12481088 |
| Hemmerlin A and Bach TJ | Farnesol-induced cell death and stimulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity in tobacco cv bright yellow-2 cells. | 2000 | Plant Physiol. | pmid:10938345 |
| Fitzpatrick AH et al. | Roles for farnesol and ABA in Arabidopsis flower development. | 2011 | Plant Signal Behav | pmid:21758018 |
| Shin KO et al. | Terpene alcohols inhibit de novo sphingolipid biosynthesis. | 2012 | Planta Med. | pmid:22274813 |
| Nevo Y et al. | The Ras antagonist, farnesylthiosalicylic acid (FTS), decreases fibrosis and improves muscle strength in dy/dy mouse model of muscular dystrophy. | 2011 | PLoS ONE | pmid:21445359 |
| Chen M et al. | Use of synthetic isoprenoids to target protein prenylation and Rho GTPases in breast cancer invasion. | 2014 | PLoS ONE | pmid:24587105 |
| Zhu J et al. | Farnesol-induced apoptosis in Candida albicans is mediated by Cdr1-p extrusion and depletion of intracellular glutathione. | 2011 | PLoS ONE | pmid:22205973 |
| Zhang L et al. | Bisbibenzyls, a new type of antifungal agent, inhibit morphogenesis switch and biofilm formation through upregulation of DPP3 in Candida albicans. | 2011 | PLoS ONE | pmid:22174935 |
| Chang W et al. | Retigeric acid B attenuates the virulence of Candida albicans via inhibiting adenylyl cyclase activity targeted by enhanced farnesol production. | 2012 | PLoS ONE | pmid:22848547 |
| Fu MS et al. | Functional characterization of the small heat shock protein Hsp12p from Candida albicans. | 2012 | PLoS ONE | pmid:22880130 |
| Zhu J et al. | Mevalonate-Farnesal Biosynthesis in Ticks: Comparative Synganglion Transcriptomics and a New Perspective. | 2016 | PLoS ONE | pmid:26959814 |
| Xu H et al. | Glucanase induces filamentation of the fungal pathogen Candida albicans. | 2013 | PLoS ONE | pmid:23737947 |
| Nyati P et al. | Farnesyl phosphatase, a Corpora allata enzyme involved in juvenile hormone biosynthesis in Aedes aegypti. | 2013 | PLoS ONE | pmid:23940797 |
| Schokoroy S et al. | Disrupting the oncogenic synergism between nucleolin and Ras results in cell growth inhibition and cell death. | 2013 | PLoS ONE | pmid:24086490 |
| Mologni L et al. | Synergistic effects of combined Wnt/KRAS inhibition in colorectal cancer cells. | 2012 | PLoS ONE | pmid:23227266 |
| Mor A et al. | Ras inhibition induces insulin sensitivity and glucose uptake. | 2011 | PLoS ONE | pmid:21738773 |
| Wu L et al. | Farnesylthiosalicylic acid sensitizes hepatocarcinoma cells to artemisinin derivatives. | 2017 | PLoS ONE | pmid:28182780 |
| Schmukler E et al. | Continuous treatment with FTS confers resistance to apoptosis and affects autophagy. | 2017 | PLoS ONE | pmid:28151959 |
| Jung SI et al. | Comparison of E,E-Farnesol Secretion and the Clinical Characteristics of Candida albicans Bloodstream Isolates from Different Multilocus Sequence Typing Clades. | 2016 | PLoS ONE | pmid:26848577 |
| Seman-Kamarulzaman AF et al. | Novel NAD+-Farnesal Dehydrogenase from Polygonum minus Leaves. Purification and Characterization of Enzyme in Juvenile Hormone III Biosynthetic Pathway in Plant. | 2016 | PLoS ONE | pmid:27560927 |
| Krause J et al. | Prostaglandin E2 from Candida albicans Stimulates the Growth of Staphylococcus aureus in Mixed Biofilms. | 2015 | PLoS ONE | pmid:26262843 |
| Mogen AB et al. | Pluronics-Formulated Farnesol Promotes Efficient Killing and Demonstrates Novel Interactions with Streptococcus mutans Biofilms. | 2015 | PLoS ONE | pmid:26222384 |
| Strube-Bloss MF et al. | Extracting the Behaviorally Relevant Stimulus: Unique Neural Representation of Farnesol, a Component of the Recruitment Pheromone of Bombus terrestris. | 2015 | PLoS ONE | pmid:26340263 |
| Madhani HD | Quorum sensing in fungi: Q&A. | 2011 | PLoS Pathog. | pmid:22046125 |
| Lopez-Medina E et al. | Candida albicans Inhibits Pseudomonas aeruginosa Virulence through Suppression of Pyochelin and Pyoverdine Biosynthesis. | 2015 | PLoS Pathog. | pmid:26313907 |
| Lutz RJ et al. | Nucleoplasmic localization of prelamin A: implications for prenylation-dependent lamin A assembly into the nuclear lamina. | 1992 | Proc. Natl. Acad. Sci. U.S.A. | pmid:1557405 |
| Ma YT and Rando RR | A microsomal endoprotease that specifically cleaves isoprenylated peptides. | 1992 | Proc. Natl. Acad. Sci. U.S.A. | pmid:1631119 |
| Kato K et al. | Isoprenoid addition to Ras protein is the critical modification for its membrane association and transforming activity. | 1992 | Proc. Natl. Acad. Sci. U.S.A. | pmid:1631135 |
| Kotti T et al. | Biphasic requirement for geranylgeraniol in hippocampal long-term potentiation. | 2008 | Proc. Natl. Acad. Sci. U.S.A. | pmid:18685105 |
| Jackson JH et al. | Farnesol modification of Kirsten-ras exon 4B protein is essential for transformation. | 1990 | Proc. Natl. Acad. Sci. U.S.A. | pmid:2183224 |
| Peleg AY et al. | Prokaryote-eukaryote interactions identified by using Caenorhabditis elegans. | 2008 | Proc. Natl. Acad. Sci. U.S.A. | pmid:18794525 |
| Mayoral JG et al. | NADP+-dependent farnesol dehydrogenase, a corpora allata enzyme involved in juvenile hormone synthesis. | 2009 | Proc. Natl. Acad. Sci. U.S.A. | pmid:19940247 |
| Caldwell GA et al. | Consequences of altered isoprenylation targets on a-factor export and bioactivity. | 1994 | Proc. Natl. Acad. Sci. U.S.A. | pmid:8108401 |
| Laezza C et al. | v-K-ras leads to preferential farnesylation of p21(ras) in FRTL-5 cells: multiple interference with the isoprenoid pathway. | 1998 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9811854 |
| Lu Y et al. | Quorum sensing controls hyphal initiation in Candida albicans through Ubr1-mediated protein degradation. | 2014 | Proc. Natl. Acad. Sci. U.S.A. | pmid:24449897 |
| Fisher JE et al. | Alendronate mechanism of action: geranylgeraniol, an intermediate in the mevalonate pathway, prevents inhibition of osteoclast formation, bone resorption, and kinase activation in vitro. | 1999 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9874784 |
| Parmryd I et al. | Protein prenylation in spinach chloroplasts. | 1999 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10468564 |
| Lai RK et al. | The gamma subunit of transducin is farnesylated. | 1990 | Proc. Natl. Acad. Sci. U.S.A. | pmid:2217200 |
| Casey PJ et al. | p21ras is modified by a farnesyl isoprenoid. | 1989 | Proc. Natl. Acad. Sci. U.S.A. | pmid:2682646 |
| Stone KJ and Strominger JL | Inhibition of sterol biosynthesis by bacitracin. | 1972 | Proc. Natl. Acad. Sci. U.S.A. | pmid:4338587 |
| Jautelat M et al. | Natural-abundance 13C nuclear magnetic resonance spectra of terpenes and carotenes. | 1970 | Proc. Natl. Acad. Sci. U.S.A. | pmid:5263764 |
| Thai L et al. | Farnesol is utilized for isoprenoid biosynthesis in plant cells via farnesyl pyrophosphate formed by successive monophosphorylation reactions. | 1999 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10557276 |
| Jansen B et al. | Novel Ras antagonist blocks human melanoma growth. | 1999 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10570191 |
| Law JH et al. | Synthesis of a material with high juvenile hormone activity. | 1966 | Proc. Natl. Acad. Sci. U.S.A. | pmid:5221241 |
| Cornforth J | Symmetry of squalene epoxidation in vivo. | 1977 | Proc. R. Soc. Lond., B, Biol. Sci. | pmid:22855 |
| Donninger C and Popják G | Studies on the biosynthesis of cholesterol. 18. The stereospecificity of mevaldate reductase and the biosynthesis of asymmetrically labelled farnesyl pyrophosphate. | 1966 | Proc. R. Soc. Lond., B, Biol. Sci. | pmid:4379290 |
| McPherson RA et al. | The novel Ras antagonist, farnesylthiosalicylate, suppresses growth of prostate cancer in vitro. | 2004 | Prostate | pmid:14968433 |
| Banfi C et al. | Proteomic analysis of human low-density lipoprotein reveals the presence of prenylcysteine lyase, a hydrogen peroxide-generating enzyme. | 2009 | Proteomics | pmid:19253276 |
| Blum R et al. | Inhibitors of chronically active ras: potential for treatment of human malignancies. | 2008 | Recent Pat Anticancer Drug Discov | pmid:18289122 |
| Jahangir T et al. | Alleviation of free radical mediated oxidative and genotoxic effects of cadmium by farnesol in Swiss albino mice. | 2005 | Redox Rep. | pmid:16438802 |
| Ilayaraja R et al. | Evaluating the binding efficiency of pheromone binding protein with its natural ligand using molecular docking and fluorescence analysis. | 2014 | Sci Rep | pmid:24903953 |