(e,z)-farnesol is a lipid of Prenol Lipids (PR) class.
We collected disease MeSH terms mapped to the references associated with (e,z)-farnesol
Authors | Title | Published | Journal | PubMed Link |
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Ferri N et al. | Isothiazole dioxide derivative 6n inhibits vascular smooth muscle cell proliferation and protein farnesylation. | 2005 | Biochem. Pharmacol. | pmid:16257390 |
Rüegg T et al. | 3-Farnesyl-2-hydroxybenzoic acid is a new anti-Helicobacter pylori compound from Piper multiplinervium. | 2006 | J Ethnopharmacol | pmid:16266794 |
Hemmerlin A et al. | Monitoring farnesol-induced toxicity in tobacco BY-2 cells with a fluorescent analog. | 2006 | Arch. Biochem. Biophys. | pmid:16307722 |
Ma YT and Rando RR | A microsomal endoprotease that specifically cleaves isoprenylated peptides. | 1992 | Proc. Natl. Acad. Sci. U.S.A. | pmid:1631119 |
Kato K et al. | Isoprenoid addition to Ras protein is the critical modification for its membrane association and transforming activity. | 1992 | Proc. Natl. Acad. Sci. U.S.A. | pmid:1631135 |
Santen RJ et al. | Farnesylthiosalicylic acid: inhibition of proliferation and enhancement of apoptosis of hormone-dependent breast cancer cells. | 2006 | Anticancer Drugs | pmid:16317288 |
Aronovich R et al. | Antiphospholipid antibodies, thrombin and LPS activate brain endothelial cells and Ras-dependent pathways through distinct mechanisms. | 2005 | Immunobiology | pmid:16325498 |
Melnykovych G et al. | Growth inhibition of leukemia cell line CEM-C1 by farnesol: effects of phosphatidylcholine and diacylglycerol. | 1992 | Biochem. Biophys. Res. Commun. | pmid:1632790 |
Ong TP et al. | Farnesol and geraniol chemopreventive activities during the initial phases of hepatocarcinogenesis involve similar actions on cell proliferation and DNA damage, but distinct actions on apoptosis, plasma cholesterol and HMGCoA reductase. | 2006 | Carcinogenesis | pmid:16332721 |
Semighini CP et al. | Farnesol-induced apoptosis in Aspergillus nidulans reveals a possible mechanism for antagonistic interactions between fungi. | 2006 | Mol. Microbiol. | pmid:16420349 |
Merino SM and Maren S | Hitting Ras where it counts: Ras antagonism in the basolateral amygdala inhibits long-term fear memory. | 2006 | Eur. J. Neurosci. | pmid:16420429 |
Jahangir T et al. | Alleviation of free radical mediated oxidative and genotoxic effects of cadmium by farnesol in Swiss albino mice. | 2005 | Redox Rep. | pmid:16438802 |
Khalil AA et al. | Isolation and characterization of a monoamine oxidase B selective inhibitor from tobacco smoke. | 2006 | Bioorg. Med. Chem. | pmid:16458520 |
Song L | A soluble form of phosphatase in Saccharomyces cerevisiae capable of converting farnesyl diphosphate into E,E-farnesol. | 2006 | Appl. Biochem. Biotechnol. | pmid:16484724 |
Xie J et al. | Microparticles developed by electrohydrodynamic atomization for the local delivery of anticancer drug to treat C6 glioma in vitro. | 2006 | Biomaterials | pmid:16490248 |
Blum R et al. | E2F1 identified by promoter and biochemical analysis as a central target of glioblastoma cell-cycle arrest in response to Ras inhibition. | 2006 | Int. J. Cancer | pmid:16496386 |
Chana RS and Brunskill NJ | Thiazolidinediones inhibit albumin uptake by proximal tubular cells through a mechanism independent of peroxisome proliferator activated receptor gamma. | 2006 | Am. J. Nephrol. | pmid:16508249 |
Semighini CP et al. | Functional characterization of the putative Aspergillus nidulans poly(ADP-ribose) polymerase homolog PrpA. | 2006 | Genetics | pmid:16510786 |
Beiner ME et al. | Ras antagonist inhibits growth and chemosensitizes human epithelial ovarian cancer cells. | 2006 Jan-Feb | Int. J. Gynecol. Cancer | pmid:16515591 |
Duncan RE and Archer MC | Farnesol induces thyroid hormone receptor (THR) beta1 but inhibits THR-mediated signaling in MCF-7 human breast cancer cells. | 2006 | Biochem. Biophys. Res. Commun. | pmid:16540091 |
Jabra-Rizk MA et al. | Effect of farnesol on Staphylococcus aureus biofilm formation and antimicrobial susceptibility. | 2006 | Antimicrob. Agents Chemother. | pmid:16569866 |
Kubista B et al. | Anticancer effects of zoledronic acid against human osteosarcoma cells. | 2006 | J. Orthop. Res. | pmid:16602111 |
Hogan DA | Talking to themselves: autoregulation and quorum sensing in fungi. | 2006 | Eukaryotic Cell | pmid:16607008 |
Jensen EC et al. | Farnesol restores wild-type colony morphology to 96% of Candida albicans colony morphology variants recovered following treatment with mutagens. | 2006 | Genome | pmid:16699554 |
Shintre MS et al. | Efficacy of an alcohol-based healthcare hand rub containing synergistic combination of farnesol and benzethonium chloride. | 2006 | Int J Hyg Environ Health | pmid:16750419 |
Nickerson KW et al. | Quorum sensing in dimorphic fungi: farnesol and beyond. | 2006 | Appl. Environ. Microbiol. | pmid:16751484 |
Berzat AC et al. | Using inhibitors of prenylation to block localization and transforming activity. | 2006 | Meth. Enzymol. | pmid:16757354 |
Jahangir T et al. | Farnesol prevents Fe-NTA-mediated renal oxidative stress and early tumour promotion markers in rats. | 2006 | Hum Exp Toxicol | pmid:16758765 |
Green TR et al. | Compartmentation of isopentenyl pyophosphate isomerase and prenyl transferase in developing castor bean endosperm. | 1975 | Biochem. Biophys. Res. Commun. | pmid:167761 |
Erlich S et al. | Ras inhibition results in growth arrest and death of androgen-dependent and androgen-independent prostate cancer cells. | 2006 | Biochem. Pharmacol. | pmid:16780807 |
Fuchs BB and Mylonakis E | Using non-mammalian hosts to study fungal virulence and host defense. | 2006 | Curr. Opin. Microbiol. | pmid:16814595 |
Saidi S et al. | In vitro synergistic effect of farnesol and human gingival cells against Candida albicans. | 2006 | Yeast | pmid:16845684 |
Rung E et al. | Depletion of substrates for protein prenylation increases apoptosis in human periovulatory granulosa cells. | 2006 | Mol. Reprod. Dev. | pmid:16868926 |
Alem MA et al. | Production of tyrosol by Candida albicans biofilms and its role in quorum sensing and biofilm development. | 2006 | Eukaryotic Cell | pmid:16980403 |
Blum R et al. | Suppression of survivin expression in glioblastoma cells by the Ras inhibitor farnesylthiosalicylic acid promotes caspase-dependent apoptosis. | 2006 | Mol. Cancer Ther. | pmid:16985068 |
Binda C et al. | Structure of the human mitochondrial monoamine oxidase B: new chemical implications for neuroprotectant drug design. | 2006 | Neurology | pmid:17030739 |
Jabra-Rizk MA et al. | Effect of farnesol on Candida dubliniensis biofilm formation and fluconazole resistance. | 2006 | FEMS Yeast Res. | pmid:17042756 |
Hasmim M et al. | Zoledronate inhibits endothelial cell adhesion, migration and survival through the suppression of multiple, prenylation-dependent signaling pathways. | 2007 | J. Thromb. Haemost. | pmid:17059425 |
Jones G et al. | The retinoid-X receptor ortholog, ultraspiracle, binds with nanomolar affinity to an endogenous morphogenetic ligand. | 2006 | FEBS J. | pmid:17064257 |
Hamada M et al. | Inhibitory activity of 1-farnesylpyridinium on the spatial control over the assembly of cell wall polysaccharides in Schizosaccharomyces pombe. | 2006 | J. Biochem. | pmid:17092950 |
Shapira S et al. | The tumor suppressor neurofibromin confers sensitivity to apoptosis by Ras-dependent and Ras-independent pathways. | 2007 | Cell Death Differ. | pmid:17096025 |
Cetin A et al. | Angiotensin II-induced MAPK phosphorylation mediated by Ras and/or phospholipase C-dependent phosphorylations but not by protein kinase C phosphorylation in cultured rat vascular smooth muscle cells. | 2007 | Pharmacology | pmid:17135774 |
Wiseman DA et al. | Cell cycle arrest by the isoprenoids perillyl alcohol, geraniol, and farnesol is mediated by p21(Cip1) and p27(Kip1) in human pancreatic adenocarcinoma cells. | 2007 | J. Pharmacol. Exp. Ther. | pmid:17138864 |
Wendland J et al. | Use of the Porcine Intestinal Epithelium (PIE)-Assay to analyze early stages of colonization by the human fungal pathogen Candida albicans. | 2006 | J. Basic Microbiol. | pmid:17139615 |
Fairn GD et al. | A chemogenomic screen in Saccharomyces cerevisiae uncovers a primary role for the mitochondria in farnesol toxicity and its regulation by the Pkc1 pathway. | 2007 | J. Biol. Chem. | pmid:17164236 |
Nokhodchi A et al. | The effect of terpene concentrations on the skin penetration of diclofenac sodium. | 2007 | Int J Pharm | pmid:17174049 |
Lombardi L et al. | Circadian rhythms in Neurospora crassa: clock mutant effects in the absence of a frq-based oscillator. | 2007 | Genetics | pmid:17237512 |
Kuroda M et al. | Sesquiterpene farnesol inhibits recycling of the C55 lipid carrier of the murein monomer precursor contributing to increased susceptibility to beta-lactams in methicillin-resistant Staphylococcus aureus. | 2007 | J. Antimicrob. Chemother. | pmid:17242033 |
Henriques M et al. | Effect of farnesol on Candida dubliniensis morphogenesis. | 2007 | Lett. Appl. Microbiol. | pmid:17257261 |
Dumitru R et al. | In vivo and in vitro anaerobic mating in Candida albicans. | 2007 | Eukaryotic Cell | pmid:17259544 |
Shintre MS et al. | Evaluation of an alcohol-based surgical hand disinfectant containing a synergistic combination of farnesol and benzethonium chloride for immediate and persistent activity against resident hand flora of volunteers and with a novel in vitro pig skin model. | 2007 | Infect Control Hosp Epidemiol | pmid:17265401 |
Navarathna DH et al. | Effect of farnesol on a mouse model of systemic candidiasis, determined by use of a DPP3 knockout mutant of Candida albicans. | 2007 | Infect. Immun. | pmid:17283095 |
Journe F et al. | Farnesol, a mevalonate pathway intermediate, stimulates MCF-7 breast cancer cell growth through farnesoid-X-receptor-mediated estrogen receptor activation. | 2008 | Breast Cancer Res. Treat. | pmid:17333335 |
Touhara K and Prestwich GD | Binding site mapping of a photoaffinity-labeled juvenile hormone binding protein. | 1992 | Biochem. Biophys. Res. Commun. | pmid:1734862 |
Blum R et al. | Gene expression signature of human cancer cell lines treated with the ras inhibitor salirasib (S-farnesylthiosalicylic acid). | 2007 | Cancer Res. | pmid:17409441 |
Crowell DN et al. | Arabidopsis thaliana plants possess a specific farnesylcysteine lyase that is involved in detoxification and recycling of farnesylcysteine. | 2007 | Plant J. | pmid:17425716 |
Woodard B et al. | 3D-QSAR of fungal quorum-sensing inhibiting analogs of farnesol. | 2007 Mar-Apr | J Environ Sci Health B | pmid:17454380 |
Navarathna DH et al. | Exogenous farnesol interferes with the normal progression of cytokine expression during candidiasis in a mouse model. | 2007 | Infect. Immun. | pmid:17517874 |
Cheng AX et al. | The rice (E)-beta-caryophyllene synthase (OsTPS3) accounts for the major inducible volatile sesquiterpenes. | 2007 | Phytochemistry | pmid:17524436 |
Zundelevich A et al. | Suppression of lung cancer tumor growth in a nude mouse model by the Ras inhibitor salirasib (farnesylthiosalicylic acid). | 2007 | Mol. Cancer Ther. | pmid:17541036 |
Kuroda M et al. | Sesquiterpene farnesol as a competitive inhibitor of lipase activity of Staphylococcus aureus. | 2007 | FEMS Microbiol. Lett. | pmid:17559400 |
Uppuluri P et al. | Farnesol-mediated inhibition of Candida albicans yeast growth and rescue by a diacylglycerol analogue. | 2007 | Yeast | pmid:17583896 |
Yue W et al. | Mechanisms of acquired resistance to endocrine therapy in hormone-dependent breast cancer cells. | 2007 Aug-Sep | J. Steroid Biochem. Mol. Biol. | pmid:17616457 |
Cugini C et al. | Farnesol, a common sesquiterpene, inhibits PQS production in Pseudomonas aeruginosa. | 2007 | Mol. Microbiol. | pmid:17640272 |
da Silva Morais A et al. | Inhibition of the Ras oncoprotein reduces proliferation of hepatocytes in vitro and in vivo in rats. | 2008 | Clin. Sci. | pmid:17678500 |
Rossignol T et al. | Transcriptional response of Candida parapsilosis following exposure to farnesol. | 2007 | Antimicrob. Agents Chemother. | pmid:17684006 |
Zhang L and Hill RP | Hypoxia enhances metastatic efficiency in HT1080 fibrosarcoma cells by increasing cell survival in lungs, not cell adhesion and invasion. | 2007 | Cancer Res. | pmid:17699784 |
Joo JH et al. | Farnesol-induced apoptosis in human lung carcinoma cells is coupled to the endoplasmic reticulum stress response. | 2007 | Cancer Res. | pmid:17699800 |
Lee H et al. | Characterization of (E,E)-farnesol and its fatty acid esters from anal scent glands of nutria (Myocastor coypus) by gas chromatography-mass spectrometry and gas chromatography-infrared spectrometry. | 2007 | J Chromatogr A | pmid:17709112 |
Marciano D et al. | Neuroprotective effects of the Ras inhibitor S-trans-trans-farnesylthiosalicylic acid, measured by diffusion-weighted imaging after traumatic brain injury in rats. | 2007 | J. Neurotrauma | pmid:17711399 |
Dionigi CP et al. | Effects of farnesol and the off-flavor derivative geosmin on Streptomyces tendae. | 1991 | Appl. Environ. Microbiol. | pmid:1785920 |
Haklai R et al. | Orally administered FTS (salirasib) inhibits human pancreatic tumor growth in nude mice. | 2008 | Cancer Chemother. Pharmacol. | pmid:17909812 |
Zvibel I et al. | The effect of Ras inhibition on the proliferation, apoptosis and matrix metalloproteases activity in rat hepatic stellate cells. | 2008 | Dig. Dis. Sci. | pmid:17934818 |
Cho T et al. | Transcriptional changes in Candida albicans Genes by both farnesol and high cell density at an early stage of morphogenesis in N-acetyl-D-glucosamine medium. | 2007 | Nihon Ishinkin Gakkai Zasshi | pmid:17975531 |
Abbasnezhad H et al. | Two different mechanisms for adhesion of Gram-negative bacterium, Pseudomonas fluorescens LP6a, to an oil-water interface. | 2008 | Colloids Surf B Biointerfaces | pmid:17997081 |
Shchepin R et al. | Influence of heterocyclic and oxime-containing farnesol analogs on quorum sensing and pathogenicity in Candida albicans. | 2008 | Bioorg. Med. Chem. | pmid:18037299 |
Davis-Hanna A et al. | Farnesol and dodecanol effects on the Candida albicans Ras1-cAMP signalling pathway and the regulation of morphogenesis. | 2008 | Mol. Microbiol. | pmid:18078440 |
Maher M et al. | Activation of TRPA1 by farnesyl thiosalicylic acid. | 2008 | Mol. Pharmacol. | pmid:18171730 |
Golczak M et al. | Metabolic basis of visual cycle inhibition by retinoid and nonretinoid compounds in the vertebrate retina. | 2008 | J. Biol. Chem. | pmid:18195010 |
Semighini CP et al. | Inhibition of Fusarium graminearum growth and development by farnesol. | 2008 | FEMS Microbiol. Lett. | pmid:18201191 |
Blum R et al. | Inhibitors of chronically active ras: potential for treatment of human malignancies. | 2008 | Recent Pat Anticancer Drug Discov | pmid:18289122 |
Teshima K and Kondo T | Analytical method for determination of allylic isoprenols in rat tissues by liquid chromatography/tandem mass spectrometry following chemical derivatization with 3-nitrophtalic anhydride. | 2008 | J Pharm Biomed Anal | pmid:18313250 |
Tsangarakis C et al. | Zeolite NaY-promoted cyclization of farnesal: a short route to nanaimoal. | 2008 | J. Org. Chem. | pmid:18321121 |
Weber K et al. | Secretion of E,E-farnesol and biofilm formation in eight different Candida species. | 2008 | Antimicrob. Agents Chemother. | pmid:18332168 |
Shimomura K et al. | Homofarnesals: female sex attractant pheromone components of the southern cowpea weevil, Callosobruchus chinensis. | 2008 | J. Chem. Ecol. | pmid:18351422 |
Rotblat B et al. | The Ras inhibitor farnesylthiosalicylic acid (Salirasib) disrupts the spatiotemporal localization of active Ras: a potential treatment for cancer. | 2008 | Meth. Enzymol. | pmid:18374183 |
Lorek J et al. | Influence of farnesol on the morphogenesis of Aspergillus niger. | 2008 | J. Basic Microbiol. | pmid:18383232 |
Marcuzzi A et al. | Natural isoprenoids are able to reduce inflammation in a mouse model of mevalonate kinase deficiency. | 2008 | Pediatr. Res. | pmid:18391837 |
Chen CK et al. | The effect of mutation of F87 on the properties of CYP102A1-CYP4C7 chimeras: altered regiospecificity and substrate selectivity. | 2008 | J. Biol. Inorg. Chem. | pmid:18392864 |
Joo JH and Jetten AM | NF-kappaB-dependent transcriptional activation in lung carcinoma cells by farnesol involves p65/RelA(Ser276) phosphorylation via the MEK-MSK1 signaling pathway. | 2008 | J. Biol. Chem. | pmid:18424438 |
Kebaara BW et al. | Candida albicans Tup1 is involved in farnesol-mediated inhibition of filamentous-growth induction. | 2008 | Eukaryotic Cell | pmid:18424510 |
McAlester G et al. | Signal-mediated interactions between Pseudomonas aeruginosa and Candida albicans. | 2008 | J. Med. Microbiol. | pmid:18436588 |
Mor A et al. | N-Ras or K-Ras inhibition increases the number and enhances the function of Foxp3 regulatory T cells. | 2008 | Eur. J. Immunol. | pmid:18461565 |
Duncan RE and Archer MC | Farnesol decreases serum triglycerides in rats: identification of mechanisms including up-regulation of PPARalpha and down-regulation of fatty acid synthase in hepatocytes. | 2008 | Lipids | pmid:18509688 |
Zhao M et al. | Determination of salirasib (S-trans,trans-farnesylthiosalicylic acid) in human plasma using liquid chromatography-tandem mass spectrometry. | 2008 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:18534927 |
Schleimer K et al. | Competition between native liver and graft in auxiliary liver transplantation in a rat model. | 2008 | Transplant. Proc. | pmid:18555091 |
Au-Yeung KK et al. | Herbal isoprenols induce apoptosis in human colon cancer cells through transcriptional activation of PPARgamma. | 2008 | Cancer Invest. | pmid:18608213 |
Geraldo IM et al. | Rapid antibacterial activity of 2 novel hand soaps: evaluation of the risk of development of bacterial resistance to the antibacterial agents. | 2008 | Infect Control Hosp Epidemiol | pmid:18616390 |
Jahangir T and Sultana S | Benzo(a)pyrene-induced genotoxicity: attenuation by farnesol in a mouse model. | 2008 | J Enzyme Inhib Med Chem | pmid:18618320 |
Muramatsu M et al. | Accumulation of prenyl alcohols by terpenoid biosynthesis inhibitors in various microorganisms. | 2008 | Appl. Microbiol. Biotechnol. | pmid:18636253 |