(e,z)-farnesol is a lipid of Prenol Lipids (PR) class.
We collected disease MeSH terms mapped to the references associated with (e,z)-farnesol
Authors | Title | Published | Journal | PubMed Link |
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Houten SM et al. | Isoprenoid biosynthesis in hereditary periodic fever syndromes and inflammation. | 2003 | Cell. Mol. Life Sci. | pmid:12861380 |
Iguchi T et al. | Nitrogen-containing bisphosphonates induce S-phase cell cycle arrest and apoptosis of myeloma cells by activating MAPK pathway and inhibiting mevalonate pathway. | 2003 | Cell. Signal. | pmid:12742232 |
Shchepin R et al. | Quorum sensing in Candida albicans: probing farnesol's mode of action with 40 natural and synthetic farnesol analogs. | 2003 | Chem. Biol. | pmid:12954333 |
Shchepin R et al. | Biologically active fluorescent farnesol analogs. | 2005 | Chem. Biol. | pmid:15975508 |
Khan R and Sultana S | Farnesol attenuates 1,2-dimethylhydrazine induced oxidative stress, inflammation and apoptotic responses in the colon of Wistar rats. | 2011 | Chem. Biol. Interact. | pmid:21453689 |
Endo S et al. | Roles of rat and human aldo-keto reductases in metabolism of farnesol and geranylgeraniol. | 2011 | Chem. Biol. Interact. | pmid:21187079 |
Qamar W and Sultana S | Farnesol ameliorates massive inflammation, oxidative stress and lung injury induced by intratracheal instillation of cigarette smoke extract in rats: an initial step in lung chemoprevention. | 2008 | Chem. Biol. Interact. | pmid:18793622 |
Moya M et al. | Enhanced steatosis by nuclear receptor ligands: a study in cultured human hepatocytes and hepatoma cells with a characterized nuclear receptor expression profile. | 2010 | Chem. Biol. Interact. | pmid:20079722 |
Horn TL et al. | Modulation of hepatic and renal drug metabolizing enzyme activities in rats by subchronic administration of farnesol. | 2005 | Chem. Biol. Interact. | pmid:15840382 |
Bondar OP et al. | Effects of farnesol on the thermotropic behavior of dimyristoylphosphatidylcholine. | 1994 | Chem. Phys. Lipids | pmid:7820904 |
Ludolph B et al. | Solution- and solid-phase synthesis of the polybasic lipid-modified C termini of Rho A and K-Ras 4B. | 2002 | Chembiochem | pmid:12210992 |
Raptis C et al. | Acid-catalyzed cyclization of terpenes under homogeneous and heterogeneous conditions as probed through stereoisotopic studies: a concerted process with competing preorganized chair and boat transition states. | 2009 | Chemistry | pmid:19780112 |
Akiyama H et al. | Actions of farnesol and xylitol against Staphylococcus aureus. | 2002 | Chemotherapy | pmid:12138327 |
Luxová A et al. | Absolute configuration of chiral terpenes in marking pheromones of bumblebees and cuckoo bumblebees. | 2004 | Chirality | pmid:15034905 |
George J et al. | Functional inhibition of Ras by S-trans,trans-farnesyl thiosalicylic acid attenuates atherosclerosis in apolipoprotein E knockout mice. | 2002 | Circulation | pmid:12021230 |
Badar T et al. | Phase I study of S-trans, trans-farnesylthiosalicylic acid (salirasib), a novel oral RAS inhibitor in patients with refractory hematologic malignancies. | 2015 | Clin Lymphoma Myeloma Leuk | pmid:25795639 |
Gana-Weisz M et al. | The Ras inhibitor S-trans,trans-farnesylthiosalicylic acid chemosensitizes human tumor cells without causing resistance. | 2002 | Clin. Cancer Res. | pmid:11839677 |
Bachireddy P et al. | Getting at MYC through RAS. | 2005 | Clin. Cancer Res. | pmid:15958607 |
Yaari S et al. | Disruption of cooperation between Ras and MycN in human neuroblastoma cells promotes growth arrest. | 2005 | Clin. Cancer Res. | pmid:15958613 |
Aizman E et al. | Therapeutic effect of farnesylthiosalicylic acid on adjuvant-induced arthritis through suppressed release of inflammatory cytokines. | 2014 | Clin. Exp. Immunol. | pmid:24215151 |
Katzav A et al. | Treatment of MRL/lpr mice, a genetic autoimmune model, with the Ras inhibitor, farnesylthiosalicylate (FTS). | 2001 | Clin. Exp. Immunol. | pmid:11737078 |
da Silva Morais A et al. | Inhibition of the Ras oncoprotein reduces proliferation of hepatocytes in vitro and in vivo in rats. | 2008 | Clin. Sci. | pmid:17678500 |
Abbasnezhad H et al. | Two different mechanisms for adhesion of Gram-negative bacterium, Pseudomonas fluorescens LP6a, to an oil-water interface. | 2008 | Colloids Surf B Biointerfaces | pmid:17997081 |
Goossens A and Merckx L | Allergic contact dermatitis from farnesol in a deodorant. | 1997 | Contact Derm. | pmid:9385513 |
Frosch PJ et al. | Patch testing with a new fragrance mix detects additional patients sensitive to perfumes and missed by the current fragrance mix. | 2005 | Contact Derm. | pmid:15859993 |
Frosch PJ et al. | Patch testing with a new fragrance mix - reactivity to the individual constituents and chemical detection in relevant cosmetic products. | 2005 | Contact Derm. | pmid:15859994 |
Hemmer W et al. | Axillary dermatitis from farnesol in a deodorant. | 2000 | Contact Derm. | pmid:10727172 |
Schnuch A et al. | Contact allergy to farnesol in 2021 consecutively patch tested patients. Results of the IVDK. | 2004 | Contact Derm. | pmid:15153123 |
Mor A et al. | Immunomodulatory properties of farnesoids: the new steroids? | 2013 | Curr. Med. Chem. | pmid:23432580 |
Gomes FI et al. | Effect of farnesol on planktonic and biofilm cells of Staphylococcus epidermidis. | 2009 | Curr. Microbiol. | pmid:19365686 |
Gomes F et al. | Effect of farnesol on structure and composition of Staphylococcus epidermidis biofilm matrix. | 2011 | Curr. Microbiol. | pmid:21800262 |
Hampton RY | Genetic analysis of hydroxymethylglutaryl-coenzyme A reductase regulated degradation. | 1998 | Curr. Opin. Lipidol. | pmid:9559264 |
Hogan DA and Muhlschlegel FA | Candida albicans developmental regulation: adenylyl cyclase as a coincidence detector of parallel signals. | 2011 | Curr. Opin. Microbiol. | pmid:22014725 |
Fuchs BB and Mylonakis E | Using non-mammalian hosts to study fungal virulence and host defense. | 2006 | Curr. Opin. Microbiol. | pmid:16814595 |
Gilpin S and Maibach H | Allergic contact dermatitis caused by farnesol: clinical relevance. | 2010 | Cutan Ocul Toxicol | pmid:20858058 |
Décanis N et al. | Farnesol promotes epithelial cell defense against Candida albicans through Toll-like receptor 2 expression, interleukin-6 and human beta-defensin 2 production. | 2009 | Cytokine | pmid:19121950 |
Scheman A et al. | European Directive fragrances in natural products. | 2014 Mar-Apr | Dermatitis | pmid:24603515 |
Thorpe JL et al. | Germ cell migration in zebrafish is dependent on HMGCoA reductase activity and prenylation. | 2004 | Dev. Cell | pmid:14960282 |
Neeman R et al. | Vitamin D and S-farnesylthiosalicylic acid have a synergistic effect on hepatic stellate cells proliferation. | 2014 | Dig. Dis. Sci. | pmid:24942325 |
Oron T et al. | Prevention of induced colitis in mice by the ras antagonist farnesylthiosalicylic acid. | 2012 | Dig. Dis. Sci. | pmid:21901261 |
Zvibel I et al. | The effect of Ras inhibition on the proliferation, apoptosis and matrix metalloproteases activity in rat hepatic stellate cells. | 2008 | Dig. Dis. Sci. | pmid:17934818 |
Gefarnate. | 1968 | Drug Ther Bull | pmid:5722353 | |
Ohguro H et al. | Carboxyl methylation and farnesylation of transducin gamma-subunit synergistically enhance its coupling with metarhodopsin II. | 1991 | EMBO J. | pmid:1935895 |
Shearer AG and Hampton RY | Lipid-mediated, reversible misfolding of a sterol-sensing domain protein. | 2005 | EMBO J. | pmid:15635451 |
Berstein LM et al. | New approaches to the understanding of tamoxifen action and resistance. | 2003 | Endocr. Relat. Cancer | pmid:12790788 |
Leitner JW et al. | Hyperinsulinemia potentiates activation of p21Ras by growth factors. | 1997 | Endocrinology | pmid:9112423 |
Bhavnani BR and Woolever CA | Formation of steroids by the pregnant mare. VI. Metabolism of [14C]farnesyl pyrophosphate and [3H]dehydroepiandrosterone injected into the fetus. | 1978 | Endocrinology | pmid:155006 |
Piispanen AE et al. | Roles of Ras1 membrane localization during Candida albicans hyphal growth and farnesol response. | 2011 | Eukaryotic Cell | pmid:21908593 |
Kebaara BW et al. | Candida albicans Tup1 is involved in farnesol-mediated inhibition of filamentous-growth induction. | 2008 | Eukaryotic Cell | pmid:18424510 |
Alem MA et al. | Production of tyrosol by Candida albicans biofilms and its role in quorum sensing and biofilm development. | 2006 | Eukaryotic Cell | pmid:16980403 |