(e,z)-farnesol

(e,z)-farnesol is a lipid of Prenol Lipids (PR) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 3613 references associated with (e,z)-farnesol in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for (e,z)-farnesol

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (e,z)-farnesol

MeSH term MeSH ID Detail
Adenocarcinoma D000230 166 associated lipids
Body Weight D001835 333 associated lipids
Candidiasis, Oral D002180 11 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Edema D004487 152 associated lipids
Fibrosis D005355 23 associated lipids
Glioblastoma D005909 27 associated lipids
Glioma D005910 112 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hypergammaglobulinemia D006942 9 associated lipids
Insulin Resistance D007333 99 associated lipids
Lung Neoplasms D008175 171 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Nephritis D009393 19 associated lipids
Neurilemmoma D009442 10 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Osteosarcoma D012516 50 associated lipids
Thyroid Neoplasms D013964 33 associated lipids
Leukemia, Myeloid, Acute D015470 19 associated lipids
HIV Infections D015658 20 associated lipids
Nerve Sheath Neoplasms D018317 4 associated lipids
Per page 10 20 50 | Total 23

PubChem Biomolecular Interactions and Pathways

All references with (e,z)-farnesol

Download all related citations
Per page 10 20 50 100 | Total 813
Authors Title Published Journal PubMed Link
Hogan DA Talking to themselves: autoregulation and quorum sensing in fungi. 2006 Eukaryotic Cell pmid:16607008
de Castro Pimentel Figueiredo B et al. The Aspergillus nidulans nucA(EndoG) homologue is not involved in cell death. 2011 Eukaryotic Cell pmid:21131437
Shareck J and Belhumeur P Modulation of morphogenesis in Candida albicans by various small molecules. 2011 Eukaryotic Cell pmid:21642508
Piispanen AE et al. Roles of Ras1 membrane localization during Candida albicans hyphal growth and farnesol response. 2011 Eukaryotic Cell pmid:21908593
Lindsay AK et al. Farnesol and cyclic AMP signaling effects on the hypha-to-yeast transition in Candida albicans. 2012 Eukaryotic Cell pmid:22886999
Hall RA et al. The quorum-sensing molecules farnesol/homoserine lactone and dodecanol operate via distinct modes of action in Candida albicans. 2011 Eukaryotic Cell pmid:21666074
Deveau A et al. Farnesol induces hydrogen peroxide resistance in Candida albicans yeast by inhibiting the Ras-cyclic AMP signaling pathway. 2010 Eukaryotic Cell pmid:20118211
Ganguly S et al. Zap1 control of cell-cell signaling in Candida albicans biofilms. 2011 Eukaryotic Cell pmid:21890817
Kebaara BW et al. Candida albicans Tup1 is involved in farnesol-mediated inhibition of filamentous-growth induction. 2008 Eukaryotic Cell pmid:18424510
Westwater C et al. Candida albicans-conditioned medium protects yeast cells from oxidative stress: a possible link between quorum sensing and oxidative stress resistance. 2005 Eukaryotic Cell pmid:16215173
Martin SW et al. Cell cycle dynamics and quorum sensing in Candida albicans chlamydospores are distinct from budding and hyphal growth. 2005 Eukaryotic Cell pmid:16002645
Enjalbert B and Whiteway M Release from quorum-sensing molecules triggers hyphal formation during Candida albicans resumption of growth. 2005 Eukaryotic Cell pmid:16002646
Alem MA et al. Production of tyrosol by Candida albicans biofilms and its role in quorum sensing and biofilm development. 2006 Eukaryotic Cell pmid:16980403
Kruppa M et al. The two-component signal transduction protein Chk1p regulates quorum sensing in Candida albicans. 2004 Eukaryotic Cell pmid:15302838
Kraitzer A et al. Novel farnesylthiosalicylate (FTS)-eluting composite structures. 2009 Eur J Pharm Sci pmid:19491026
Töyräs A et al. Inhibition of mevalonate pathway is involved in alendronate-induced cell growth inhibition, but not in cytokine secretion from macrophages in vitro. 2003 Eur J Pharm Sci pmid:12885386
Tisch D et al. Activation of signaling pathways in HL60 cells and human neutrophils by farnesylthiosalicylate. 1996 Eur. J. Biochem. pmid:9022678
Mackie H and Overton KH Hydrolysis and isomerization of trans,trans-farnesyl diphosphate by Andrographis tissue-culture enzymes. 1977 Eur. J. Biochem. pmid:198206
Beedle AS et al. The stereochemistry of hydrogen transfer from NADPH catalysed by 3-hydroxy-3-methylglutaryl-coenzyme A reductase from rat liver. 1972 Eur. J. Biochem. pmid:4403574
Mau CJ et al. Protein farnesyltransferase inhibitors interfere with farnesyl diphosphate binding by rubber transferase. 2003 Eur. J. Biochem. pmid:14511375
Parmryd I et al. Identification of spinach farnesyl protein transferase. Dithiothreitol as an acceptor in vitro. 1995 Eur. J. Biochem. pmid:8575428
Schneider-Merck T et al. The Ras inhibitor farnesylthiosalicyclic acid (FTS) prevents nodule formation and development of preneoplastic foci of altered hepatocytes in rats. 2009 Eur. J. Cancer pmid:19427195
Zhao Y et al. 6-C-(E-phenylethenyl)naringenin induces cell growth inhibition and cytoprotective autophagy in colon cancer cells. 2016 Eur. J. Cancer pmid:27710830
Munro E et al. Inhibition of human vascular smooth muscle cell proliferation by lovastatin: the role of isoprenoid intermediates of cholesterol synthesis. 1994 Eur. J. Clin. Invest. pmid:7890015
Lim CS et al. Candida and invasive candidiasis: back to basics. 2012 Eur. J. Clin. Microbiol. Infect. Dis. pmid:21544694
Mor A et al. N-Ras or K-Ras inhibition increases the number and enhances the function of Foxp3 regulatory T cells. 2008 Eur. J. Immunol. pmid:18461565
Merino SM and Maren S Hitting Ras where it counts: Ras antagonism in the basolateral amygdala inhibits long-term fear memory. 2006 Eur. J. Neurosci. pmid:16420429
Nishio E et al. 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitor impairs cell p4fferentiation in cultured adipogenic cells (3T3-L1). 1996 Eur. J. Pharmacol. pmid:8773465
Mor A et al. Ras inhibition increases the frequency and function of regulatory T cells and attenuates type-1 diabetes in non-obese diabetic mice. 2009 Eur. J. Pharmacol. pmid:19527709
Nishio E et al. Alpha1-adrenoreceptor stimulation causes vascular smooth muscle cell hypertrophy: a possible role for isoprenoid intermediates. 1998 Eur. J. Pharmacol. pmid:9650858
Szilvassy Z et al. Improvement of nitrergic relaxation by farnesol of the sphincter of Oddi from hypercholesterolaemic rabbits. 1998 Eur. J. Pharmacol. pmid:9721042
Sari R et al. Impairment by lovastatin of neural relaxation of the rabbit sphincter of Oddi. 2001 Eur. J. Pharmacol. pmid:11734192
Sakata T et al. Chemical ecology of oribatid mites III. Chemical composition of oil gland exudates from two oribatid mites, Trhypochthoniellus sp. and Trhypochthonius japonicus (Acari: Trhypochthoniidae). 2003 Exp. Appl. Acarol. pmid:14635814
Torabi S and Mo H Trans, trans-farnesol as a mevalonate-derived inducer of murine 3T3-F442A pre-adipocyte differentiation. 2016 Exp. Biol. Med. (Maywood) pmid:26660152
Crick DC et al. Geranylgeraniol promotes entry of UT-2 cells into the cell cycle in the absence of mevalonate. 1997 Exp. Cell Res. pmid:9087171
Meigs TE et al. Farnesyl acetate, a derivative of an isoprenoid of the mevalonate pathway, inhibits DNA replication in hamster and human cells. 1995 Exp. Cell Res. pmid:7641798
Cheng QF et al. Effect of perillic acid, a putative isoprenylation inhibitor, on the cultured rat lens. 2001 Exp. Eye Res. pmid:11446774
Qamar W et al. Benzo(a)pyrene-induced pulmonary inflammation, edema, surfactant dysfunction, and injuries in rats: alleviation by farnesol. 2012 Exp. Lung Res. pmid:22168545
Navarro-Moll MC et al. In vitro and in vivo activity of three sesquiterpenes against L(3) larvae of Anisakis type I. 2011 Exp. Parasitol. pmid:20932829
Boisvenue RJ et al. Haemonchus contortus: effects of compounds with juvenile hormone activity on the in vitro development of infective larvae. 1977 Exp. Parasitol. pmid:862711
Piérard GE et al. Miconazole, a pharmacological barrier to skin fungal infections. 2012 Expert Opin Pharmacother pmid:22568580
Supuran CT Nanoparticles for controlled release of anti-biofilm agents WO2014130994 (A1): a patent evaluation. 2015 Expert Opin Ther Pat pmid:26028186
Taylor MM et al. Enhanced apoptosis through farnesol inhibition of phospholipase D signal transduction. 2005 FEBS J. pmid:16176276
Jones G et al. The retinoid-X receptor ortholog, ultraspiracle, binds with nanomolar affinity to an endogenous morphogenetic ligand. 2006 FEBS J. pmid:17064257
Hamada M et al. Farnesylpyridinium, an analog of isoprenoid farnesol, induces apoptosis but suppresses apoptotic body formation in human promyelocytic leukemia cells. 2002 FEBS Lett. pmid:11943160
Takahashi N et al. Dual action of isoprenols from herbal medicines on both PPARgamma and PPARalpha in 3T3-L1 adipocytes and HepG2 hepatocytes. 2002 FEBS Lett. pmid:11943173
Machida K and Tanaka T Farnesol-induced generation of reactive oxygen species dependent on mitochondrial transmembrane potential hyperpolarization mediated by F(0)F(1)-ATPase in yeast. 1999 FEBS Lett. pmid:10580101
Beedle AS et al. The stereochemistry of the reduction of mevaldic acid-coenzyme A hemithioacetal by rat liver 3-hydroxy-3-methylglutaryl coenzyme A reductase. 1972 FEBS Lett. pmid:4405222
Rioja A et al. Preferential induction of apoptosis of leukaemic cells by farnesol. 2000 FEBS Lett. pmid:10675556
Pérez-Sala D et al. Analogs of farnesylcysteine induce apoptosis in HL-60 cells. 1998 FEBS Lett. pmid:9600259

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