(e,z)-farnesol

(e,z)-farnesol is a lipid of Prenol Lipids (PR) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 3613 references associated with (e,z)-farnesol in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for (e,z)-farnesol

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (e,z)-farnesol

MeSH term MeSH ID Detail
Adenocarcinoma D000230 166 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Lung Neoplasms D008175 171 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Osteosarcoma D012516 50 associated lipids
Glioma D005910 112 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Thyroid Neoplasms D013964 33 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Fibrosis D005355 23 associated lipids
Leukemia, Myeloid, Acute D015470 19 associated lipids
Hypergammaglobulinemia D006942 9 associated lipids
Glioblastoma D005909 27 associated lipids
Nephritis D009393 19 associated lipids
HIV Infections D015658 20 associated lipids
Neurilemmoma D009442 10 associated lipids
Insulin Resistance D007333 99 associated lipids
Candidiasis, Oral D002180 11 associated lipids
Nerve Sheath Neoplasms D018317 4 associated lipids
Per page 10 20 50 | Total 23

PubChem Biomolecular Interactions and Pathways

All references with (e,z)-farnesol

Download all related citations
Per page 10 20 50 100 | Total 813
Authors Title Published Journal PubMed Link
Shintre MS et al. Evaluation of an alcohol-based surgical hand disinfectant containing a synergistic combination of farnesol and benzethonium chloride for immediate and persistent activity against resident hand flora of volunteers and with a novel in vitro pig skin model. 2007 Infect Control Hosp Epidemiol pmid:17265401
Navarathna DH et al. Effect of farnesol on a mouse model of systemic candidiasis, determined by use of a DPP3 knockout mutant of Candida albicans. 2007 Infect. Immun. pmid:17283095
Journe F et al. Farnesol, a mevalonate pathway intermediate, stimulates MCF-7 breast cancer cell growth through farnesoid-X-receptor-mediated estrogen receptor activation. 2008 Breast Cancer Res. Treat. pmid:17333335
Touhara K and Prestwich GD Binding site mapping of a photoaffinity-labeled juvenile hormone binding protein. 1992 Biochem. Biophys. Res. Commun. pmid:1734862
Blum R et al. Gene expression signature of human cancer cell lines treated with the ras inhibitor salirasib (S-farnesylthiosalicylic acid). 2007 Cancer Res. pmid:17409441
Crowell DN et al. Arabidopsis thaliana plants possess a specific farnesylcysteine lyase that is involved in detoxification and recycling of farnesylcysteine. 2007 Plant J. pmid:17425716
Woodard B et al. 3D-QSAR of fungal quorum-sensing inhibiting analogs of farnesol. 2007 Mar-Apr J Environ Sci Health B pmid:17454380
Navarathna DH et al. Exogenous farnesol interferes with the normal progression of cytokine expression during candidiasis in a mouse model. 2007 Infect. Immun. pmid:17517874
Cheng AX et al. The rice (E)-beta-caryophyllene synthase (OsTPS3) accounts for the major inducible volatile sesquiterpenes. 2007 Phytochemistry pmid:17524436
Zundelevich A et al. Suppression of lung cancer tumor growth in a nude mouse model by the Ras inhibitor salirasib (farnesylthiosalicylic acid). 2007 Mol. Cancer Ther. pmid:17541036
Kuroda M et al. Sesquiterpene farnesol as a competitive inhibitor of lipase activity of Staphylococcus aureus. 2007 FEMS Microbiol. Lett. pmid:17559400
Uppuluri P et al. Farnesol-mediated inhibition of Candida albicans yeast growth and rescue by a diacylglycerol analogue. 2007 Yeast pmid:17583896
Yue W et al. Mechanisms of acquired resistance to endocrine therapy in hormone-dependent breast cancer cells. 2007 Aug-Sep J. Steroid Biochem. Mol. Biol. pmid:17616457
Cugini C et al. Farnesol, a common sesquiterpene, inhibits PQS production in Pseudomonas aeruginosa. 2007 Mol. Microbiol. pmid:17640272
da Silva Morais A et al. Inhibition of the Ras oncoprotein reduces proliferation of hepatocytes in vitro and in vivo in rats. 2008 Clin. Sci. pmid:17678500
Rossignol T et al. Transcriptional response of Candida parapsilosis following exposure to farnesol. 2007 Antimicrob. Agents Chemother. pmid:17684006
Zhang L and Hill RP Hypoxia enhances metastatic efficiency in HT1080 fibrosarcoma cells by increasing cell survival in lungs, not cell adhesion and invasion. 2007 Cancer Res. pmid:17699784
Joo JH et al. Farnesol-induced apoptosis in human lung carcinoma cells is coupled to the endoplasmic reticulum stress response. 2007 Cancer Res. pmid:17699800
Lee H et al. Characterization of (E,E)-farnesol and its fatty acid esters from anal scent glands of nutria (Myocastor coypus) by gas chromatography-mass spectrometry and gas chromatography-infrared spectrometry. 2007 J Chromatogr A pmid:17709112
Marciano D et al. Neuroprotective effects of the Ras inhibitor S-trans-trans-farnesylthiosalicylic acid, measured by diffusion-weighted imaging after traumatic brain injury in rats. 2007 J. Neurotrauma pmid:17711399
Dionigi CP et al. Effects of farnesol and the off-flavor derivative geosmin on Streptomyces tendae. 1991 Appl. Environ. Microbiol. pmid:1785920
Haklai R et al. Orally administered FTS (salirasib) inhibits human pancreatic tumor growth in nude mice. 2008 Cancer Chemother. Pharmacol. pmid:17909812
Zvibel I et al. The effect of Ras inhibition on the proliferation, apoptosis and matrix metalloproteases activity in rat hepatic stellate cells. 2008 Dig. Dis. Sci. pmid:17934818
Cho T et al. Transcriptional changes in Candida albicans Genes by both farnesol and high cell density at an early stage of morphogenesis in N-acetyl-D-glucosamine medium. 2007 Nihon Ishinkin Gakkai Zasshi pmid:17975531
Abbasnezhad H et al. Two different mechanisms for adhesion of Gram-negative bacterium, Pseudomonas fluorescens LP6a, to an oil-water interface. 2008 Colloids Surf B Biointerfaces pmid:17997081
Shchepin R et al. Influence of heterocyclic and oxime-containing farnesol analogs on quorum sensing and pathogenicity in Candida albicans. 2008 Bioorg. Med. Chem. pmid:18037299
Davis-Hanna A et al. Farnesol and dodecanol effects on the Candida albicans Ras1-cAMP signalling pathway and the regulation of morphogenesis. 2008 Mol. Microbiol. pmid:18078440
Maher M et al. Activation of TRPA1 by farnesyl thiosalicylic acid. 2008 Mol. Pharmacol. pmid:18171730
Golczak M et al. Metabolic basis of visual cycle inhibition by retinoid and nonretinoid compounds in the vertebrate retina. 2008 J. Biol. Chem. pmid:18195010
Semighini CP et al. Inhibition of Fusarium graminearum growth and development by farnesol. 2008 FEMS Microbiol. Lett. pmid:18201191
Blum R et al. Inhibitors of chronically active ras: potential for treatment of human malignancies. 2008 Recent Pat Anticancer Drug Discov pmid:18289122
Teshima K and Kondo T Analytical method for determination of allylic isoprenols in rat tissues by liquid chromatography/tandem mass spectrometry following chemical derivatization with 3-nitrophtalic anhydride. 2008 J Pharm Biomed Anal pmid:18313250
Tsangarakis C et al. Zeolite NaY-promoted cyclization of farnesal: a short route to nanaimoal. 2008 J. Org. Chem. pmid:18321121
Weber K et al. Secretion of E,E-farnesol and biofilm formation in eight different Candida species. 2008 Antimicrob. Agents Chemother. pmid:18332168
Shimomura K et al. Homofarnesals: female sex attractant pheromone components of the southern cowpea weevil, Callosobruchus chinensis. 2008 J. Chem. Ecol. pmid:18351422
Rotblat B et al. The Ras inhibitor farnesylthiosalicylic acid (Salirasib) disrupts the spatiotemporal localization of active Ras: a potential treatment for cancer. 2008 Meth. Enzymol. pmid:18374183
Lorek J et al. Influence of farnesol on the morphogenesis of Aspergillus niger. 2008 J. Basic Microbiol. pmid:18383232
Marcuzzi A et al. Natural isoprenoids are able to reduce inflammation in a mouse model of mevalonate kinase deficiency. 2008 Pediatr. Res. pmid:18391837
Chen CK et al. The effect of mutation of F87 on the properties of CYP102A1-CYP4C7 chimeras: altered regiospecificity and substrate selectivity. 2008 J. Biol. Inorg. Chem. pmid:18392864
Joo JH and Jetten AM NF-kappaB-dependent transcriptional activation in lung carcinoma cells by farnesol involves p65/RelA(Ser276) phosphorylation via the MEK-MSK1 signaling pathway. 2008 J. Biol. Chem. pmid:18424438
Kebaara BW et al. Candida albicans Tup1 is involved in farnesol-mediated inhibition of filamentous-growth induction. 2008 Eukaryotic Cell pmid:18424510
McAlester G et al. Signal-mediated interactions between Pseudomonas aeruginosa and Candida albicans. 2008 J. Med. Microbiol. pmid:18436588
Mor A et al. N-Ras or K-Ras inhibition increases the number and enhances the function of Foxp3 regulatory T cells. 2008 Eur. J. Immunol. pmid:18461565
Duncan RE and Archer MC Farnesol decreases serum triglycerides in rats: identification of mechanisms including up-regulation of PPARalpha and down-regulation of fatty acid synthase in hepatocytes. 2008 Lipids pmid:18509688
Zhao M et al. Determination of salirasib (S-trans,trans-farnesylthiosalicylic acid) in human plasma using liquid chromatography-tandem mass spectrometry. 2008 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:18534927
Schleimer K et al. Competition between native liver and graft in auxiliary liver transplantation in a rat model. 2008 Transplant. Proc. pmid:18555091
Au-Yeung KK et al. Herbal isoprenols induce apoptosis in human colon cancer cells through transcriptional activation of PPARgamma. 2008 Cancer Invest. pmid:18608213
Geraldo IM et al. Rapid antibacterial activity of 2 novel hand soaps: evaluation of the risk of development of bacterial resistance to the antibacterial agents. 2008 Infect Control Hosp Epidemiol pmid:18616390
Jahangir T and Sultana S Benzo(a)pyrene-induced genotoxicity: attenuation by farnesol in a mouse model. 2008 J Enzyme Inhib Med Chem pmid:18618320
Muramatsu M et al. Accumulation of prenyl alcohols by terpenoid biosynthesis inhibitors in various microorganisms. 2008 Appl. Microbiol. Biotechnol. pmid:18636253

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