(e,z)-farnesol

(e,z)-farnesol is a lipid of Prenol Lipids (PR) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 3613 references associated with (e,z)-farnesol in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for (e,z)-farnesol

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (e,z)-farnesol

MeSH term MeSH ID Detail
Lupus Erythematosus, Systemic D008180 43 associated lipids
Osteosarcoma D012516 50 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Insulin Resistance D007333 99 associated lipids
Glioma D005910 112 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Edema D004487 152 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Per page 10 20 50 | Total 23

PubChem Biomolecular Interactions and Pathways

All references with (e,z)-farnesol

Download all related citations
Per page 10 20 50 100 | Total 813
Authors Title Published Journal PubMed Link
Lapczynski A et al. Fragrance material review on farnesol. 2008 Food Chem. Toxicol. pmid:18640198
Hisajima T et al. Protective effects of farnesol against oral candidiasis in mice. 2008 Microbiol. Immunol. pmid:18667031
Savoldi M et al. Farnesol induces the transcriptional accumulation of the Aspergillus nidulans Apoptosis-Inducing Factor (AIF)-like mitochondrial oxidoreductase. 2008 Mol. Microbiol. pmid:18681941
Kotti T et al. Biphasic requirement for geranylgeraniol in hippocampal long-term potentiation. 2008 Proc. Natl. Acad. Sci. U.S.A. pmid:18685105
Koo H Strategies to enhance the biological effects of fluoride on dental biofilms. 2008 Adv. Dent. Res. pmid:18694872
Scheper MA et al. Farnesol, a fungal quorum-sensing molecule triggers apoptosis in human oral squamous carcinoma cells. 2008 Neoplasia pmid:18714396
Qamar W and Sultana S Farnesol ameliorates massive inflammation, oxidative stress and lung injury induced by intratracheal instillation of cigarette smoke extract in rats: an initial step in lung chemoprevention. 2008 Chem. Biol. Interact. pmid:18793622
Peleg AY et al. Prokaryote-eukaryote interactions identified by using Caenorhabditis elegans. 2008 Proc. Natl. Acad. Sci. U.S.A. pmid:18794525
Cushion MT et al. Biofilm formation by Pneumocystis spp. 2009 Eukaryotic Cell pmid:18820078
Muramatsu M et al. Various oils and detergents enhance the microbial production of farnesol and related prenyl alcohols. 2008 J. Biosci. Bioeng. pmid:18930003
Goldberg L et al. Salirasib (farnesyl thiosalicylic acid) for brain tumor treatment: a convection-enhanced drug delivery study in rats. 2008 Mol. Cancer Ther. pmid:19001442
Cho T et al. [Farnesol as a quorum-sensing molecule in Candida albicans]. 2008 Nihon Ishinkin Gakkai Zasshi pmid:19001754
Goldberg L et al. New derivatives of farnesylthiosalicylic acid (salirasib) for cancer treatment: farnesylthiosalicylamide inhibits tumor growth in nude mice models. 2009 J. Med. Chem. pmid:19072665
Togashi N et al. Effects of two terpene alcohols on the antibacterial activity and the mode of action of farnesol against Staphylococcus aureus. 2008 Molecules pmid:19078849
Décanis N et al. Farnesol promotes epithelial cell defense against Candida albicans through Toll-like receptor 2 expression, interleukin-6 and human beta-defensin 2 production. 2009 Cytokine pmid:19121950
Ohto C et al. Prenyl alcohol production by expression of exogenous isopentenyl diphosphate isomerase and farnesyl diphosphate synthase genes in Escherichia coli. 2009 Biosci. Biotechnol. Biochem. pmid:19129660
Pando R et al. The Ras antagonist farnesylthiosalicylic acid ameliorates experimental myocarditis in the rat. 2010 Mar-Apr Cardiovasc. Pathol. pmid:19144546
Fujiyama A et al. S-farnesylation and methyl esterification of C-terminal domain of yeast RAS2 protein prior to fatty acid acylation. 1991 J. Biol. Chem. pmid:1917931
Eglin D et al. Farnesol-modified biodegradable polyurethanes for cartilage tissue engineering. 2010 J Biomed Mater Res A pmid:19191318
Banfi C et al. Proteomic analysis of human low-density lipoprotein reveals the presence of prenylcysteine lyase, a hydrogen peroxide-generating enzyme. 2009 Proteomics pmid:19253276
Ohguro H et al. Carboxyl methylation and farnesylation of transducin gamma-subunit synergistically enhance its coupling with metarhodopsin II. 1991 EMBO J. pmid:1935895
Shirtliff ME et al. Farnesol-induced apoptosis in Candida albicans. 2009 Antimicrob. Agents Chemother. pmid:19364863
Gomes FI et al. Effect of farnesol on planktonic and biofilm cells of Staphylococcus epidermidis. 2009 Curr. Microbiol. pmid:19365686
Derengowski LS et al. Antimicrobial effect of farnesol, a Candida albicans quorum sensing molecule, on Paracoccidioides brasiliensis growth and morphogenesis. 2009 Ann. Clin. Microbiol. Antimicrob. pmid:19402910
Rodríguez C et al. Statins normalize vascular lysyl oxidase down-regulation induced by proatherogenic risk factors. 2009 Cardiovasc. Res. pmid:19406911
Pando R et al. Ras inhibition attenuates myocardial ischemia-reperfusion injury. 2009 Biochem. Pharmacol. pmid:19426696
Schneider-Merck T et al. The Ras inhibitor farnesylthiosalicyclic acid (FTS) prevents nodule formation and development of preneoplastic foci of altered hepatocytes in rats. 2009 Eur. J. Cancer pmid:19427195
Rhome R and Del Poeta M Lipid signaling in pathogenic fungi. 2009 Annu. Rev. Microbiol. pmid:19450140
Chaudhary SC et al. Chemopreventive effect of farnesol on DMBA/TPA-induced skin tumorigenesis: involvement of inflammation, Ras-ERK pathway and apoptosis. 2009 Life Sci. pmid:19470390
Tsimberidou AM et al. Phase 1 first-in-human clinical study of S-trans,trans-farnesylthiosalicylic acid (salirasib) in patients with solid tumors. 2010 Cancer Chemother. Pharmacol. pmid:19484470
Kraitzer A et al. Novel farnesylthiosalicylate (FTS)-eluting composite structures. 2009 Eur J Pharm Sci pmid:19491026
Abe S et al. Suppression of anti-Candida activity of macrophages by a quorum-sensing molecule, farnesol, through induction of oxidative stress. 2009 Microbiol. Immunol. pmid:19493200
Joo JH and Jetten AM Molecular mechanisms involved in farnesol-induced apoptosis. 2010 Cancer Lett. pmid:19520495
Mor A et al. Ras inhibition increases the frequency and function of regulatory T cells and attenuates type-1 diabetes in non-obese diabetic mice. 2009 Eur. J. Pharmacol. pmid:19527709
Song L Recovery of E,E-farnesol from cultures of yeast erg9 mutants: extraction with polymeric beads and purification by normal-phase chromatography. 2009 Jul-Aug Biotechnol. Prog. pmid:19569196
Muramatsu M et al. Alkaline pH enhances farnesol production by Saccharomyces cerevisiae. 2009 J. Biosci. Bioeng. pmid:19577192
Xiao Y et al. A two-component female-produced pheromone of the spider Pholcus beijingensis. 2009 J. Chem. Ecol. pmid:19579045
Goldstein JL and Brown MS Regulation of the mevalonate pathway. 1990 Nature pmid:1967820
Rennemeier C et al. Microbial quorum-sensing molecules induce acrosome loss and cell death in human spermatozoa. 2009 Infect. Immun. pmid:19687207
Chen F et al. Tooth-binding micelles for dental caries prevention. 2009 Antimicrob. Agents Chemother. pmid:19704121
Koo H and Jeon JG Naturally occurring molecules as alternative therapeutic agents against cariogenic biofilms. 2009 Adv. Dent. Res. pmid:19717411
Chen CK et al. Scanning chimeragenesis: the approach used to change the substrate selectivity of fatty acid monooxygenase CYP102A1 to that of terpene omega-hydroxylase CYP4C7. 2010 J. Biol. Inorg. Chem. pmid:19727859
Doan K et al. In vivo and in vitro skin absorption of lipophilic compounds, dibutyl phthalate, farnesol and geraniol in the hairless guinea pig. 2010 Food Chem. Toxicol. pmid:19747520
Raptis C et al. Acid-catalyzed cyclization of terpenes under homogeneous and heterogeneous conditions as probed through stereoisotopic studies: a concerted process with competing preorganized chair and boat transition states. 2009 Chemistry pmid:19780112
Räikkönen J et al. Mevalonate pathway intermediates downregulate zoledronic acid-induced isopentenyl pyrophosphate and ATP analog formation in human breast cancer cells. 2010 Biochem. Pharmacol. pmid:19819230
Mackie H and Overton KH Hydrolysis and isomerization of trans,trans-farnesyl diphosphate by Andrographis tissue-culture enzymes. 1977 Eur. J. Biochem. pmid:198206
Hanker AB et al. Differential requirement of CAAX-mediated posttranslational processing for Rheb localization and signaling. 2010 Oncogene pmid:19838215
Chagas CE et al. Farnesol inhibits cell proliferation and induces apoptosis after partial hepatectomy in rats. 2009 Sep-Oct Acta Cir Bras pmid:19851690
Jeon JG et al. Influences of naturally occurring agents in combination with fluoride on gene expression and structural organization of Streptococcus mutans in biofilms. 2009 BMC Microbiol. pmid:19863808
Unnanuntana A et al. The effects of farnesol on Staphylococcus aureus biofilms and osteoblasts. An in vitro study. 2009 J Bone Joint Surg Am pmid:19884443

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