(e,z)-farnesol

(e,z)-farnesol is a lipid of Prenol Lipids (PR) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 3613 references associated with (e,z)-farnesol in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for (e,z)-farnesol

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (e,z)-farnesol

MeSH term MeSH ID Detail
Leukemia, Myeloid, Acute D015470 19 associated lipids
HIV Infections D015658 20 associated lipids
Nerve Sheath Neoplasms D018317 4 associated lipids
Per page 10 20 50 | Total 23

PubChem Biomolecular Interactions and Pathways

All references with (e,z)-farnesol

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Per page 10 20 50 100 | Total 813
Authors Title Published Journal PubMed Link
Satoh T et al. The effects of pravastatin, an HMG-CoA reductase inhibitor, on cell viability and DNA production of rat hepatocytes. 1996 Life Sci. pmid:8831797
Tanaka H et al. MEKA/phosducin attenuates hydrophobicity of transducin beta gamma subunits without binding to farnesyl moiety. 1996 Biochem. Biophys. Res. Commun. pmid:8687440
Keller RK et al. Farnesol is not the nonsterol regulator mediating degradation of HMG-CoA reductase in rat liver. 1996 Arch. Biochem. Biophys. pmid:8645011
Koyama T et al. Identification of significant residues in the substrate binding site of Bacillus stearothermophilus farnesyl diphosphate synthase. 1996 Biochemistry pmid:8755734
Bostedor RG et al. Farnesol-derived dicarboxylic acids in the urine of animals treated with zaragozic acid A or with farnesol. 1997 J. Biol. Chem. pmid:9083051
Roullet JB et al. Inhibition of Ca2+ uptake into A7r5 vascular smooth muscle cells by farnesol: lack of effect on membrane fluidity and Ca2+-ATPase activities. 1997 J. Hypertens. pmid:9488229
Roullet JB et al. Farnesol inhibits L-type Ca2+ channels in vascular smooth muscle cells. 1997 J. Biol. Chem. pmid:9405427
Nozawa Y et al. Stachybotrin C and parvisporin, novel neuritogenic compounds. II. Structure determination. 1997 J. Antibiot. pmid:9315075
Saisho Y et al. Determination of farnesyl pyrophosphate in dog and human plasma by high-performance liquid chromatography with fluorescence detection. 1997 Anal. Biochem. pmid:9324945
Gana-Weisz M et al. The Ras antagonist S-farnesylthiosalicylic acid induces inhibition of MAPK activation. 1997 Biochem. Biophys. Res. Commun. pmid:9367867
Goossens A and Merckx L Allergic contact dermatitis from farnesol in a deodorant. 1997 Contact Derm. pmid:9385513
Meigs TE and Simoni RD Farnesol as a regulator of HMG-CoA reductase degradation: characterization and role of farnesyl pyrophosphatase. 1997 Arch. Biochem. Biophys. pmid:9281305
Crick DC et al. Novel salvage pathway utilizing farnesol and geranylgeraniol for protein isoprenylation. 1997 Biochem. Biophys. Res. Commun. pmid:9299388
Van Dessel G et al. Internalisation of short-chain isoprenyl diphosphates by chromaffin cells from bovine adrenal medulla. 1997 Biochem. Biophys. Res. Commun. pmid:9299441
Blazer-Yost BL et al. Protein prenylation is required for aldosterone-stimulated Na+ transport. 1997 Am. J. Physiol. pmid:9227422
Crick DC et al. Geranylgeraniol promotes entry of UT-2 cells into the cell cycle in the absence of mevalonate. 1997 Exp. Cell Res. pmid:9087171
Leitner JW et al. Hyperinsulinemia potentiates activation of p21Ras by growth factors. 1997 Endocrinology pmid:9112423
Flint OP et al. Inhibition of cholesterol synthesis by squalene synthase inhibitors does not induce myotoxicity in vitro. 1997 Toxicol. Appl. Pharmacol. pmid:9221828
Tamone SL et al. Identification and characterization of methyl farnesoate binding proteins from the crab, Cancer magister. 1997 Gen. Comp. Endocrinol. pmid:9038249
Westfall D et al. Metabolism of farnesol: phosphorylation of farnesol by rat liver microsomal and peroxisomal fractions. 1997 Biochem. Biophys. Res. Commun. pmid:9015362
Ghosh PM et al. Lovastatin induces apoptosis by inhibiting mitotic and post-mitotic events in cultured mesangial cells. 1997 Biochim. Biophys. Acta pmid:9398081
Zhang L et al. Isolation and characterization of a prenylcysteine lyase from bovine brain. 1997 J. Biol. Chem. pmid:9287348
Andres DA et al. Expression cloning of a novel farnesylated protein, RDJ2, encoding a DnaJ protein homologue. 1997 Arch. Biochem. Biophys. pmid:9328291
Vaidya S et al. Massive production of farnesol-derived dicarboxylic acids in mice treated with the squalene synthase inhibitor zaragozic acid A. 1998 Arch. Biochem. Biophys. pmid:9647670
Aharonson Z et al. Stringent structural requirements for anti-Ras activity of S-prenyl analogues. 1998 Biochim. Biophys. Acta pmid:9545527
Ura H et al. Selective cytotoxicity of farnesylamine to pancreatic carcinoma cells and Ki-ras-transformed fibroblasts. 1998 Mol. Carcinog. pmid:9496909
Haklai R et al. Dislodgment and accelerated degradation of Ras. 1998 Biochemistry pmid:9477957
Hampton RY Genetic analysis of hydroxymethylglutaryl-coenzyme A reductase regulated degradation. 1998 Curr. Opin. Lipidol. pmid:9559264
Desrosiers RR and Béliveau R Regulation by GTPgammaS of protein carboxylmethyltransferase activity in kidney brush border membranes. 1998 Arch. Biochem. Biophys. pmid:9514644
Miquel K et al. Competitive inhibition of choline phosphotransferase by geranylgeraniol and farnesol inhibits phosphatidylcholine synthesis and induces apoptosis in human lung adenocarcinoma A549 cells. 1998 J. Biol. Chem. pmid:9748300
Laezza C et al. v-K-ras leads to preferential farnesylation of p21(ras) in FRTL-5 cells: multiple interference with the isoprenoid pathway. 1998 Proc. Natl. Acad. Sci. U.S.A. pmid:9811854
Ferdinandy P et al. Rapid pacing-induced preconditioning is recaptured by farnesol treatment in hearts of cholesterol-fed rats: role of polyprenyl derivatives and nitric oxide. 1998 Mol. Cell. Biochem. pmid:9774182
Shipman CM et al. The bisphosphonate incadronate (YM175) causes apoptosis of human myeloma cells in vitro by inhibiting the mevalonate pathway. 1998 Cancer Res. pmid:9850051
Aboushadi N and Krisans SK Analysis of isoprenoid biosynthesis in peroxisomal-deficient Pex2 CHO cell lines. 1998 J. Lipid Res. pmid:9741690
Bentinger M et al. Phosphorylation of farnesol in rat liver microsomes: properties of farnesol kinase and farnesyl phosphate kinase. 1998 Arch. Biochem. Biophys. pmid:9606952
Nishio E et al. Alpha1-adrenoreceptor stimulation causes vascular smooth muscle cell hypertrophy: a possible role for isoprenoid intermediates. 1998 Eur. J. Pharmacol. pmid:9650858
Szilvassy Z et al. Improvement of nitrergic relaxation by farnesol of the sphincter of Oddi from hypercholesterolaemic rabbits. 1998 Eur. J. Pharmacol. pmid:9721042
Machida K et al. Farnesol-induced generation of reactive oxygen species via indirect inhibition of the mitochondrial electron transport chain in the yeast Saccharomyces cerevisiae. 1998 J. Bacteriol. pmid:9721283
Strickland CL et al. Crystal structure of farnesyl protein transferase complexed with a CaaX peptide and farnesyl diphosphate analogue. 1998 Biochemistry pmid:9843427
Llorente-Cortés V et al. Esterified cholesterol accumulation induced by aggregated LDL uptake in human vascular smooth muscle cells is reduced by HMG-CoA reductase inhibitors. 1998 Arterioscler. Thromb. Vasc. Biol. pmid:9598832
Pérez-Sala D et al. Analogs of farnesylcysteine induce apoptosis in HL-60 cells. 1998 FEBS Lett. pmid:9600259
Rubins JB et al. Lovastatin induces apoptosis in malignant mesothelioma cells. 1998 Am. J. Respir. Crit. Care Med. pmid:9603146
Crick DC et al. Geranylgeraniol overcomes the block of cell proliferation by lovastatin in C6 glioma cells. 1998 J. Neurochem. pmid:9603204
Pei ZM et al. Role of farnesyltransferase in ABA regulation of guard cell anion channels and plant water loss. 1998 Science pmid:9765153
Hanley K et al. Fetal epidermal differentiation and barrier development In vivo is accelerated by nuclear hormone receptor activators. 1999 J. Invest. Dermatol. pmid:10571735
Machida K and Tanaka T Farnesol-induced generation of reactive oxygen species dependent on mitochondrial transmembrane potential hyperpolarization mediated by F(0)F(1)-ATPase in yeast. 1999 FEBS Lett. pmid:10580101
Thai L et al. Farnesol is utilized for isoprenoid biosynthesis in plant cells via farnesyl pyrophosphate formed by successive monophosphorylation reactions. 1999 Proc. Natl. Acad. Sci. U.S.A. pmid:10557276
Jansen B et al. Novel Ras antagonist blocks human melanoma growth. 1999 Proc. Natl. Acad. Sci. U.S.A. pmid:10570191
Elad G et al. Targeting of K-Ras 4B by S-trans,trans-farnesyl thiosalicylic acid. 1999 Biochim. Biophys. Acta pmid:10590312
Reif S et al. The Ras antagonist, farnesylthiosalicylic acid (FTS), inhibits experimentally-induced liver cirrhosis in rats. 1999 J. Hepatol. pmid:10604579

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