(e,z)-farnesol

(e,z)-farnesol is a lipid of Prenol Lipids (PR) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 3613 references associated with (e,z)-farnesol in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for (e,z)-farnesol

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (e,z)-farnesol

MeSH term MeSH ID Detail
Adenocarcinoma D000230 166 associated lipids
Lung Neoplasms D008175 171 associated lipids
Body Weight D001835 333 associated lipids
Per page 10 20 50 | Total 23

PubChem Biomolecular Interactions and Pathways

All references with (e,z)-farnesol

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Per page 10 20 50 100 | Total 813
Authors Title Published Journal PubMed Link
Kuroda M et al. Sesquiterpene farnesol inhibits recycling of the C55 lipid carrier of the murein monomer precursor contributing to increased susceptibility to beta-lactams in methicillin-resistant Staphylococcus aureus. 2007 J. Antimicrob. Chemother. pmid:17242033
Katragkou A et al. In vitro interactions between farnesol and fluconazole, amphotericin B or micafungin against Candida albicans biofilms. 2015 J. Antimicrob. Chemother. pmid:25288679
Navarathna DH et al. Enhanced pathogenicity of Candida albicans pre-treated with subinhibitory concentrations of fluconazole in a mouse model of disseminated candidiasis. 2005 J. Antimicrob. Chemother. pmid:16239285
Berrocal A et al. Quorum sensing activity in Ophiostoma ulmi: effects of fusel oils and branched chain amino acids on yeast-mycelial dimorphism. 2012 J. Appl. Microbiol. pmid:22519968
Miyakawa T et al. Role of metabolism of the mating pheromone in sexual differentiation of the heterobasidiomycete Rhodosporidium toruloides. 1982 J. Bacteriol. pmid:7050081
Machida K et al. Farnesol-induced generation of reactive oxygen species via indirect inhibition of the mitochondrial electron transport chain in the yeast Saccharomyces cerevisiae. 1998 J. Bacteriol. pmid:9721283
Cantwell SG et al. Biodegradation of acyclic isoprenoids by Pseudomonas species. 1978 J. Bacteriol. pmid:681275
Lorek J et al. Influence of farnesol on the morphogenesis of Aspergillus niger. 2008 J. Basic Microbiol. pmid:18383232
Wendland J et al. Use of the Porcine Intestinal Epithelium (PIE)-Assay to analyze early stages of colonization by the human fungal pathogen Candida albicans. 2006 J. Basic Microbiol. pmid:17139615
Saito Y and Ogura K Biosynthesis of menaquinones. Enzymatic prenylation of 1,4-dihydroxy-2-naphthoate by Micrococcus luteus membrane fractions. 1981 J. Biochem. pmid:7275947
Nishino T et al. Enzymatic formation of nerolidol in cell-free extract of Rhodotorula glutinis. 1982 J. Biochem. pmid:6891702
Takahashi I and Ogura K Farnesyl pyrophosphate synthetase from Bacillus subtilis. 1981 J. Biochem. pmid:6792191
Hamada M et al. Inhibitory activity of 1-farnesylpyridinium on the spatial control over the assembly of cell wall polysaccharides in Schizosaccharomyces pombe. 2006 J. Biochem. pmid:17092950
Bradfute DL et al. Squalene synthase-deficient mutant of Chinese hamster ovary cells. 1992 J. Biol. Chem. pmid:1526971
Gibbs JB et al. Selective inhibition of farnesyl-protein transferase blocks ras processing in vivo. 1993 J. Biol. Chem. pmid:8463291
Maltese WA and Erdman RA Characterization of isoprenoid involved in the post-translational modification of mammalian cell proteins. 1989 J. Biol. Chem. pmid:2808372
Keller RK et al. Studies on the regulation of glycoprotein biosynthesis. An investigation of the rate-limiting steps of dolichyl phosphate biosynthesis. 1979 J. Biol. Chem. pmid:489612
Gonzalez-Pacanowska D et al. Isopentenoid synthesis in isolated embryonic Drosophila cells. Farnesol catabolism and omega-oxidation. 1988 J. Biol. Chem. pmid:3335546
Bostedor RG et al. Farnesol-derived dicarboxylic acids in the urine of animals treated with zaragozic acid A or with farnesol. 1997 J. Biol. Chem. pmid:9083051
Koeppe JK et al. A specific photoaffinity label for hemolymph and ovarian juvenile hormone-binding proteins in Leucophaea maderae. 1984 J. Biol. Chem. pmid:6699014
Christenson JG et al. Enzymatic synthesis of the antigen carrier lipid. 1969 J. Biol. Chem. pmid:4311788
Popják G et al. Biosynthesis and structure of a new intermediate between farnesyl pyrophosphate and squalene. 1969 J. Biol. Chem. pmid:4388617
Heinstein PF et al. Biosynthesis of gossypol. Incorporation of mevalonate-2-14C and isoprenyl pyrophosphates. 1970 J. Biol. Chem. pmid:4318479
Roullet JB et al. Farnesol inhibits L-type Ca2+ channels in vascular smooth muscle cells. 1997 J. Biol. Chem. pmid:9405427
Edmond J et al. Presqualene alcohol. Further evidence on the structure of a C 30 precursor of squalene. 1971 J. Biol. Chem. pmid:4399596
Allen CM et al. A long chain terpenyl pyrophosphate synthetase from Micrococcus lysodeikticus. 1967 J. Biol. Chem. pmid:4290445
Dorsey JK and Porter JW The inhibition of mevalonic kinase by geranyl and farnesyl pyrophosphates. 1968 J. Biol. Chem. pmid:4300840
Carel K et al. Insulin stimulates mitogen-activated protein kinase by a Ras-independent pathway in 3T3-L1 adipocytes. 1996 J. Biol. Chem. pmid:8940037
McGuire TF et al. Platelet-derived growth factor receptor tyrosine phosphorylation requires protein geranylgeranylation but not farnesylation. 1996 J. Biol. Chem. pmid:8910319
Zhang L et al. Isolation and characterization of a prenylcysteine lyase from bovine brain. 1997 J. Biol. Chem. pmid:9287348
Fukada Y et al. Effects of carboxyl methylation of photoreceptor G protein gamma-subunit in visual transduction. 1994 J. Biol. Chem. pmid:8106497
Gavey KL and Scallen TJ Nonparticipation of 105,000 x g liver supernatant or sterol carrier protein in the enzymatic conversion of farnesyl pyrophosphate to squalene by rat liver microsomes. 1978 J. Biol. Chem. pmid:209043
Miquel K et al. Competitive inhibition of choline phosphotransferase by geranylgeraniol and farnesol inhibits phosphatidylcholine synthesis and induces apoptosis in human lung adenocarcinoma A549 cells. 1998 J. Biol. Chem. pmid:9748300
Niv H et al. Membrane interactions of a constitutively active GFP-Ki-Ras 4B and their role in signaling. Evidence from lateral mobility studies. 1999 J. Biol. Chem. pmid:9880539
Agnew WS and Popják G Squalene synthetase. Stoichiometry and kinetics of presqualene pyrophosphate and squalene synthesis by yeast microsomes. 1978 J. Biol. Chem. pmid:26684
Slakey LL et al. The effects of fasting, refeeding, and time of day on the levels of enzymes effecting the conversion of -hydroxy- -methylglutaryl-coenzyme A to squalene. 1972 J. Biol. Chem. pmid:4337504
Polito A et al. Artificial substrates in squalene and sterol biosynthesis. 1972 J. Biol. Chem. pmid:4337856
Rosado JA and Sage SO Role of the ERK pathway in the activation of store-mediated calcium entry in human platelets. 2001 J. Biol. Chem. pmid:11278479
Wright MM et al. Uncoupling farnesol-induced apoptosis from its inhibition of phosphatidylcholine synthesis. 2001 J. Biol. Chem. pmid:11306571
Daily D et al. Glutaredoxin protects cerebellar granule neurons from dopamine-induced apoptosis by dual activation of the ras-phosphoinositide 3-kinase and jun n-terminal kinase pathways. 2001 J. Biol. Chem. pmid:11290748
Epstein WW and Rilling HC Studies on the mechanism of squalene biosynthesis. The structure of presqualene pyrophosphate. 1970 J. Biol. Chem. pmid:4318477
Muscio F et al. Prequalene pyrophosphate. A normal intermediate in squalene biosynthesis. 1974 J. Biol. Chem. pmid:4152099
Yang W et al. Protein farnesylation is critical for maintaining normal cell morphology and canavanine resistance in Schizosaccharomyces pombe. 2000 J. Biol. Chem. pmid:10617635
Hanley K et al. Farnesol stimulates differentiation in epidermal keratinocytes via PPARalpha. 2000 J. Biol. Chem. pmid:10753967
Tschantz WR et al. Lysosomal prenylcysteine lyase is a FAD-dependent thioether oxidase. 2001 J. Biol. Chem. pmid:11078725
Correll CC et al. Identification of farnesol as the non-sterol derivative of mevalonic acid required for the accelerated degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase. 1994 J. Biol. Chem. pmid:8021239
Sever N et al. Insig-dependent ubiquitination and degradation of mammalian 3-hydroxy-3-methylglutaryl-CoA reductase stimulated by sterols and geranylgeraniol. 2003 J. Biol. Chem. pmid:14563840
Fogelman AM et al. Abnormal induction of 3-hydroxy-3-methylglutaryl coenzyme A reductase in leukocytes from subjects with heterozygous familial hypercholesterolemia. 1975 J. Biol. Chem. pmid:1116997
de Ropp JS and Troy FA 2H NMR investigation of the organization and dynamics of polyisoprenols in membranes. 1985 J. Biol. Chem. pmid:4066690
Touhara K and Prestwich GD Juvenile hormone epoxide hydrolase. Photoaffinity labeling, purification, and characterization from tobacco hornworm eggs. 1993 J. Biol. Chem. pmid:8396141

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