(e,z)-farnesol

(e,z)-farnesol is a lipid of Prenol Lipids (PR) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 3613 references associated with (e,z)-farnesol in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for (e,z)-farnesol

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (e,z)-farnesol

MeSH term MeSH ID Detail
Nerve Sheath Neoplasms D018317 4 associated lipids
Hypergammaglobulinemia D006942 9 associated lipids
Neurilemmoma D009442 10 associated lipids
Candidiasis, Oral D002180 11 associated lipids
Leukemia, Myeloid, Acute D015470 19 associated lipids
Nephritis D009393 19 associated lipids
HIV Infections D015658 20 associated lipids
Fibrosis D005355 23 associated lipids
Glioblastoma D005909 27 associated lipids
Thyroid Neoplasms D013964 33 associated lipids
Per page 10 20 50 | Total 23

PubChem Biomolecular Interactions and Pathways

All references with (e,z)-farnesol

Download all related citations
Per page 10 20 50 100 | Total 813
Authors Title Published Journal PubMed Link
Chen F et al. Tooth-binding micelles for dental caries prevention. 2009 Antimicrob. Agents Chemother. pmid:19704121
Brilhante RS et al. Effect of farnesol on growth, ergosterol biosynthesis, and cell permeability in Coccidioides posadasii. 2013 Antimicrob. Agents Chemother. pmid:23459491
Langford ML et al. Activity and toxicity of farnesol towards Candida albicans are dependent on growth conditions. 2010 Antimicrob. Agents Chemother. pmid:19933803
Sharma M and Prasad R The quorum-sensing molecule farnesol is a modulator of drug efflux mediated by ABC multidrug transporters and synergizes with drugs in Candida albicans. 2011 Antimicrob. Agents Chemother. pmid:21768514
Rossignol T et al. Transcriptional response of Candida parapsilosis following exposure to farnesol. 2007 Antimicrob. Agents Chemother. pmid:17684006
Hornby JM et al. Farnesol biosynthesis in Candida albicans: cellular response to sterol inhibition by zaragozic acid B. 2003 Antimicrob. Agents Chemother. pmid:12821501
Brehm-Stecher BF and Johnson EA Sensitization of Staphylococcus aureus and Escherichia coli to antibiotics by the sesquiterpenoids nerolidol, farnesol, bisabolol, and apritone. 2003 Antimicrob. Agents Chemother. pmid:14506058
Falsetta ML et al. Novel antibiofilm chemotherapy targets exopolysaccharide synthesis and stress tolerance in Streptococcus mutans to modulate virulence expression in vivo. 2012 Antimicrob. Agents Chemother. pmid:22985885
Hornby JM and Nickerson KW Enhanced production of farnesol by Candida albicans treated with four azoles. 2004 Antimicrob. Agents Chemother. pmid:15155241
Pfister C et al. Detection and quantification of farnesol-induced apoptosis in difficult primary cell cultures by TaqMan protein assay. 2013 Apoptosis pmid:23315006
Song L A soluble form of phosphatase in Saccharomyces cerevisiae capable of converting farnesyl diphosphate into E,E-farnesol. 2006 Appl. Biochem. Biotechnol. pmid:16484724
Dionigi CP et al. Effects of farnesol and the off-flavor derivative geosmin on Streptomyces tendae. 1991 Appl. Environ. Microbiol. pmid:1785920
Hornby JM et al. Quorum sensing in the dimorphic fungus Candida albicans is mediated by farnesol. 2001 Appl. Environ. Microbiol. pmid:11425711
de Salas F et al. Quorum-Sensing Mechanisms Mediated by Farnesol in Ophiostoma piceae: Effect on Secretion of Sterol Esterase. 2015 Appl. Environ. Microbiol. pmid:25888179
Ramage G et al. Inhibition of Candida albicans biofilm formation by farnesol, a quorum-sensing molecule. 2002 Appl. Environ. Microbiol. pmid:12406738
Hornby JM et al. Inoculum size effect in dimorphic fungi: extracellular control of yeast-mycelium dimorphism in Ceratocystis ulmi. 2004 Appl. Environ. Microbiol. pmid:15006753
Mosel DD et al. Farnesol concentrations required to block germ tube formation in Candida albicans in the presence and absence of serum. 2005 Appl. Environ. Microbiol. pmid:16085901
Nickerson KW et al. Quorum sensing in dimorphic fungi: farnesol and beyond. 2006 Appl. Environ. Microbiol. pmid:16751484
Muramatsu M et al. Accumulation of prenyl alcohols by terpenoid biosynthesis inhibitors in various microorganisms. 2008 Appl. Microbiol. Biotechnol. pmid:18636253
Suzue G et al. Presence of squalene in Staphylococcus. 1968 Arch. Biochem. Biophys. pmid:5650319
Havel CM and Watson JA Isopentenoid synthesis in isolated embryonic Drosophila cells: absolute, basal mevalonate synthesis rate determination. 1992 Arch. Biochem. Biophys. pmid:1567218
Bai M and Prestwich GD Inhibition and activation of porcine squalene epoxidase. 1992 Arch. Biochem. Biophys. pmid:1536566
Saito A and Rilling HC The formation of cyclic sesquiterpenes from farnesyl pyrophosphate by prenyltransferase. 1981 Arch. Biochem. Biophys. pmid:7259201
Vaidya S et al. Massive production of farnesol-derived dicarboxylic acids in mice treated with the squalene synthase inhibitor zaragozic acid A. 1998 Arch. Biochem. Biophys. pmid:9647670
Keenan MV and Allen CM Characterization of undecaprenyl pyrophosphate synthetase from Lactobacillus plantarum. 1974 Arch. Biochem. Biophys. pmid:4599964
Dugan RE and Porter JW Hog liver squalene synthetase: the partial purification of the particulate enzyme and kinetic analysis of the reaction. 1972 Arch. Biochem. Biophys. pmid:4403691
Jungalwala FB and Porter JW Biosynthesis of phytoene from isopentenyl and farnesyl pyrophosphates by a partially purified tomato enzyme system. 1967 Arch. Biochem. Biophys. pmid:4293186
Meigs TE and Simoni RD Farnesol as a regulator of HMG-CoA reductase degradation: characterization and role of farnesyl pyrophosphatase. 1997 Arch. Biochem. Biophys. pmid:9281305
Benedict CR et al. Properties of farnesyl pyrophosphate synthetase of pig liver. 1965 Arch. Biochem. Biophys. pmid:4284635
Krishna G et al. Enzymic conversion of farnesyl pyrophosphate to squalene. 1966 Arch. Biochem. Biophys. pmid:4380977
Desrosiers RR and Béliveau R Regulation by GTPgammaS of protein carboxylmethyltransferase activity in kidney brush border membranes. 1998 Arch. Biochem. Biophys. pmid:9514644
Bentinger M et al. Phosphorylation of farnesol in rat liver microsomes: properties of farnesol kinase and farnesyl phosphate kinase. 1998 Arch. Biochem. Biophys. pmid:9606952
Baba T et al. Dehydrodolichyl diphosphate synthetase from rat seminiferous tubules. 1987 Arch. Biochem. Biophys. pmid:3813545
Parmryd I and Dallner G In vivo prenylation of rat proteins: modification of proteins with penta- and hexaprenyl groups. 1999 Arch. Biochem. Biophys. pmid:10190969
Xu L and Simoni RD The inhibition of degradation of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase by sterol regulatory element binding protein cleavage-activating protein requires four phenylalanine residues in span 6 of HMG-CoA reductase transmembrane domain. 2003 Arch. Biochem. Biophys. pmid:12781775
Hemmerlin A et al. Monitoring farnesol-induced toxicity in tobacco BY-2 cells with a fluorescent analog. 2006 Arch. Biochem. Biophys. pmid:16307722
Keller RK et al. Farnesol is not the nonsterol regulator mediating degradation of HMG-CoA reductase in rat liver. 1996 Arch. Biochem. Biophys. pmid:8645011
Andres DA et al. Expression cloning of a novel farnesylated protein, RDJ2, encoding a DnaJ protein homologue. 1997 Arch. Biochem. Biophys. pmid:9328291
Aclé D et al. Activity of the corpora allata of adult female Leucophaea maderae: effects of mating and feeding. 1990 Arch. Insect Biochem. Physiol. pmid:2134173
Luft UC et al. Farnesol blocks the L-type Ca2+ channel by targeting the alpha 1C subunit. 1999 Arterioscler. Thromb. Vasc. Biol. pmid:10195923
Llorente-Cortés V et al. Esterified cholesterol accumulation induced by aggregated LDL uptake in human vascular smooth muscle cells is reduced by HMG-CoA reductase inhibitors. 1998 Arterioscler. Thromb. Vasc. Biol. pmid:9598832
George J et al. Inhibition of intimal thickening in the rat carotid artery injury model by a nontoxic Ras inhibitor. 2004 Arterioscler. Thromb. Vasc. Biol. pmid:14670932
Frenkel J et al. Lack of isoprenoid products raises ex vivo interleukin-1beta secretion in hyperimmunoglobulinemia D and periodic fever syndrome. 2002 Arthritis Rheum. pmid:12384940
Corsini A et al. Relationship between mevalonate pathway and arterial myocyte proliferation: in vitro studies with inhibitors of HMG-CoA reductase. 1993 Atherosclerosis pmid:8216498
Giricz Z et al. Role of cholesterol-enriched diet and the mevalonate pathway in cardiac nitric oxide synthesis. 2003 Basic Res. Cardiol. pmid:12955403
Kamiya Y et al. Metabolites of mating pheromone, rhodotorucine A, by a cells of Rhodosporidium toruloides. 1980 Biochem. Biophys. Res. Commun. pmid:7396935
András IE et al. Lipid rafts and functional caveolae regulate HIV-induced amyloid beta accumulation in brain endothelial cells. 2012 Biochem. Biophys. Res. Commun. pmid:22490665
Crick DC et al. Farnesol is utilized for protein isoprenylation and the biosynthesis of cholesterol in mammalian cells. 1995 Biochem. Biophys. Res. Commun. pmid:7794274
Voziyan PA et al. Mechanism of farnesol cytotoxicity: further evidence for the role of PKC-dependent signal transduction in farnesol-induced apoptotic cell death. 1995 Biochem. Biophys. Res. Commun. pmid:7626062
Fliesler SJ and Keller RK Metabolism of [3H]farnesol to cholesterol and cholesterogenic intermediates in the living rat eye. 1995 Biochem. Biophys. Res. Commun. pmid:7763243

Table of Content