| MeSH term | MeSH ID | Detail |
|---|---|---|
| Adenocarcinoma | D000230 | 166 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Candidiasis, Oral | D002180 | 11 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Fibrosis | D005355 | 23 associated lipids |
| Glioblastoma | D005909 | 27 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
(e,z)-farnesol
(e,z)-farnesol is a lipid of Prenol Lipids (PR) class.
Cross Reference
There are no associated biomedical information in the current reference collection.
Current reference collection contains 3613 references associated with (e,z)-farnesol in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.
Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.
Here are additional resources we collected from PubChem and MeSH for (e,z)-farnesol
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with (e,z)-farnesol
PubChem Biomolecular Interactions and Pathways
All references with (e,z)-farnesol
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Ferri N et al. | Isothiazole dioxide derivative 6n inhibits vascular smooth muscle cell proliferation and protein farnesylation. | 2005 | Biochem. Pharmacol. | pmid:16257390 |
| Rüegg T et al. | 3-Farnesyl-2-hydroxybenzoic acid is a new anti-Helicobacter pylori compound from Piper multiplinervium. | 2006 | J Ethnopharmacol | pmid:16266794 |
| Hemmerlin A et al. | Monitoring farnesol-induced toxicity in tobacco BY-2 cells with a fluorescent analog. | 2006 | Arch. Biochem. Biophys. | pmid:16307722 |
| Ma YT and Rando RR | A microsomal endoprotease that specifically cleaves isoprenylated peptides. | 1992 | Proc. Natl. Acad. Sci. U.S.A. | pmid:1631119 |
| Kato K et al. | Isoprenoid addition to Ras protein is the critical modification for its membrane association and transforming activity. | 1992 | Proc. Natl. Acad. Sci. U.S.A. | pmid:1631135 |
| Santen RJ et al. | Farnesylthiosalicylic acid: inhibition of proliferation and enhancement of apoptosis of hormone-dependent breast cancer cells. | 2006 | Anticancer Drugs | pmid:16317288 |
| Aronovich R et al. | Antiphospholipid antibodies, thrombin and LPS activate brain endothelial cells and Ras-dependent pathways through distinct mechanisms. | 2005 | Immunobiology | pmid:16325498 |
| Melnykovych G et al. | Growth inhibition of leukemia cell line CEM-C1 by farnesol: effects of phosphatidylcholine and diacylglycerol. | 1992 | Biochem. Biophys. Res. Commun. | pmid:1632790 |
| Ong TP et al. | Farnesol and geraniol chemopreventive activities during the initial phases of hepatocarcinogenesis involve similar actions on cell proliferation and DNA damage, but distinct actions on apoptosis, plasma cholesterol and HMGCoA reductase. | 2006 | Carcinogenesis | pmid:16332721 |
| Semighini CP et al. | Farnesol-induced apoptosis in Aspergillus nidulans reveals a possible mechanism for antagonistic interactions between fungi. | 2006 | Mol. Microbiol. | pmid:16420349 |
| Merino SM and Maren S | Hitting Ras where it counts: Ras antagonism in the basolateral amygdala inhibits long-term fear memory. | 2006 | Eur. J. Neurosci. | pmid:16420429 |
| Jahangir T et al. | Alleviation of free radical mediated oxidative and genotoxic effects of cadmium by farnesol in Swiss albino mice. | 2005 | Redox Rep. | pmid:16438802 |
| Khalil AA et al. | Isolation and characterization of a monoamine oxidase B selective inhibitor from tobacco smoke. | 2006 | Bioorg. Med. Chem. | pmid:16458520 |
| Song L | A soluble form of phosphatase in Saccharomyces cerevisiae capable of converting farnesyl diphosphate into E,E-farnesol. | 2006 | Appl. Biochem. Biotechnol. | pmid:16484724 |
| Xie J et al. | Microparticles developed by electrohydrodynamic atomization for the local delivery of anticancer drug to treat C6 glioma in vitro. | 2006 | Biomaterials | pmid:16490248 |
| Blum R et al. | E2F1 identified by promoter and biochemical analysis as a central target of glioblastoma cell-cycle arrest in response to Ras inhibition. | 2006 | Int. J. Cancer | pmid:16496386 |
| Chana RS and Brunskill NJ | Thiazolidinediones inhibit albumin uptake by proximal tubular cells through a mechanism independent of peroxisome proliferator activated receptor gamma. | 2006 | Am. J. Nephrol. | pmid:16508249 |
| Semighini CP et al. | Functional characterization of the putative Aspergillus nidulans poly(ADP-ribose) polymerase homolog PrpA. | 2006 | Genetics | pmid:16510786 |
| Beiner ME et al. | Ras antagonist inhibits growth and chemosensitizes human epithelial ovarian cancer cells. | 2006 Jan-Feb | Int. J. Gynecol. Cancer | pmid:16515591 |
| Duncan RE and Archer MC | Farnesol induces thyroid hormone receptor (THR) beta1 but inhibits THR-mediated signaling in MCF-7 human breast cancer cells. | 2006 | Biochem. Biophys. Res. Commun. | pmid:16540091 |
| Jabra-Rizk MA et al. | Effect of farnesol on Staphylococcus aureus biofilm formation and antimicrobial susceptibility. | 2006 | Antimicrob. Agents Chemother. | pmid:16569866 |
| Kubista B et al. | Anticancer effects of zoledronic acid against human osteosarcoma cells. | 2006 | J. Orthop. Res. | pmid:16602111 |
| Hogan DA | Talking to themselves: autoregulation and quorum sensing in fungi. | 2006 | Eukaryotic Cell | pmid:16607008 |
| Jensen EC et al. | Farnesol restores wild-type colony morphology to 96% of Candida albicans colony morphology variants recovered following treatment with mutagens. | 2006 | Genome | pmid:16699554 |
| Shintre MS et al. | Efficacy of an alcohol-based healthcare hand rub containing synergistic combination of farnesol and benzethonium chloride. | 2006 | Int J Hyg Environ Health | pmid:16750419 |
| Nickerson KW et al. | Quorum sensing in dimorphic fungi: farnesol and beyond. | 2006 | Appl. Environ. Microbiol. | pmid:16751484 |
| Berzat AC et al. | Using inhibitors of prenylation to block localization and transforming activity. | 2006 | Meth. Enzymol. | pmid:16757354 |
| Jahangir T et al. | Farnesol prevents Fe-NTA-mediated renal oxidative stress and early tumour promotion markers in rats. | 2006 | Hum Exp Toxicol | pmid:16758765 |
| Green TR et al. | Compartmentation of isopentenyl pyophosphate isomerase and prenyl transferase in developing castor bean endosperm. | 1975 | Biochem. Biophys. Res. Commun. | pmid:167761 |
| Erlich S et al. | Ras inhibition results in growth arrest and death of androgen-dependent and androgen-independent prostate cancer cells. | 2006 | Biochem. Pharmacol. | pmid:16780807 |
| Fuchs BB and Mylonakis E | Using non-mammalian hosts to study fungal virulence and host defense. | 2006 | Curr. Opin. Microbiol. | pmid:16814595 |
| Saidi S et al. | In vitro synergistic effect of farnesol and human gingival cells against Candida albicans. | 2006 | Yeast | pmid:16845684 |
| Rung E et al. | Depletion of substrates for protein prenylation increases apoptosis in human periovulatory granulosa cells. | 2006 | Mol. Reprod. Dev. | pmid:16868926 |
| Alem MA et al. | Production of tyrosol by Candida albicans biofilms and its role in quorum sensing and biofilm development. | 2006 | Eukaryotic Cell | pmid:16980403 |
| Blum R et al. | Suppression of survivin expression in glioblastoma cells by the Ras inhibitor farnesylthiosalicylic acid promotes caspase-dependent apoptosis. | 2006 | Mol. Cancer Ther. | pmid:16985068 |
| Binda C et al. | Structure of the human mitochondrial monoamine oxidase B: new chemical implications for neuroprotectant drug design. | 2006 | Neurology | pmid:17030739 |
| Jabra-Rizk MA et al. | Effect of farnesol on Candida dubliniensis biofilm formation and fluconazole resistance. | 2006 | FEMS Yeast Res. | pmid:17042756 |
| Hasmim M et al. | Zoledronate inhibits endothelial cell adhesion, migration and survival through the suppression of multiple, prenylation-dependent signaling pathways. | 2007 | J. Thromb. Haemost. | pmid:17059425 |
| Jones G et al. | The retinoid-X receptor ortholog, ultraspiracle, binds with nanomolar affinity to an endogenous morphogenetic ligand. | 2006 | FEBS J. | pmid:17064257 |
| Hamada M et al. | Inhibitory activity of 1-farnesylpyridinium on the spatial control over the assembly of cell wall polysaccharides in Schizosaccharomyces pombe. | 2006 | J. Biochem. | pmid:17092950 |
| Shapira S et al. | The tumor suppressor neurofibromin confers sensitivity to apoptosis by Ras-dependent and Ras-independent pathways. | 2007 | Cell Death Differ. | pmid:17096025 |
| Cetin A et al. | Angiotensin II-induced MAPK phosphorylation mediated by Ras and/or phospholipase C-dependent phosphorylations but not by protein kinase C phosphorylation in cultured rat vascular smooth muscle cells. | 2007 | Pharmacology | pmid:17135774 |
| Wiseman DA et al. | Cell cycle arrest by the isoprenoids perillyl alcohol, geraniol, and farnesol is mediated by p21(Cip1) and p27(Kip1) in human pancreatic adenocarcinoma cells. | 2007 | J. Pharmacol. Exp. Ther. | pmid:17138864 |
| Wendland J et al. | Use of the Porcine Intestinal Epithelium (PIE)-Assay to analyze early stages of colonization by the human fungal pathogen Candida albicans. | 2006 | J. Basic Microbiol. | pmid:17139615 |
| Fairn GD et al. | A chemogenomic screen in Saccharomyces cerevisiae uncovers a primary role for the mitochondria in farnesol toxicity and its regulation by the Pkc1 pathway. | 2007 | J. Biol. Chem. | pmid:17164236 |
| Nokhodchi A et al. | The effect of terpene concentrations on the skin penetration of diclofenac sodium. | 2007 | Int J Pharm | pmid:17174049 |
| Lombardi L et al. | Circadian rhythms in Neurospora crassa: clock mutant effects in the absence of a frq-based oscillator. | 2007 | Genetics | pmid:17237512 |
| Kuroda M et al. | Sesquiterpene farnesol inhibits recycling of the C55 lipid carrier of the murein monomer precursor contributing to increased susceptibility to beta-lactams in methicillin-resistant Staphylococcus aureus. | 2007 | J. Antimicrob. Chemother. | pmid:17242033 |
| Henriques M et al. | Effect of farnesol on Candida dubliniensis morphogenesis. | 2007 | Lett. Appl. Microbiol. | pmid:17257261 |
| Dumitru R et al. | In vivo and in vitro anaerobic mating in Candida albicans. | 2007 | Eukaryotic Cell | pmid:17259544 |
| Shintre MS et al. | Evaluation of an alcohol-based surgical hand disinfectant containing a synergistic combination of farnesol and benzethonium chloride for immediate and persistent activity against resident hand flora of volunteers and with a novel in vitro pig skin model. | 2007 | Infect Control Hosp Epidemiol | pmid:17265401 |
| Navarathna DH et al. | Effect of farnesol on a mouse model of systemic candidiasis, determined by use of a DPP3 knockout mutant of Candida albicans. | 2007 | Infect. Immun. | pmid:17283095 |
| Journe F et al. | Farnesol, a mevalonate pathway intermediate, stimulates MCF-7 breast cancer cell growth through farnesoid-X-receptor-mediated estrogen receptor activation. | 2008 | Breast Cancer Res. Treat. | pmid:17333335 |
| Touhara K and Prestwich GD | Binding site mapping of a photoaffinity-labeled juvenile hormone binding protein. | 1992 | Biochem. Biophys. Res. Commun. | pmid:1734862 |
| Blum R et al. | Gene expression signature of human cancer cell lines treated with the ras inhibitor salirasib (S-farnesylthiosalicylic acid). | 2007 | Cancer Res. | pmid:17409441 |
| Crowell DN et al. | Arabidopsis thaliana plants possess a specific farnesylcysteine lyase that is involved in detoxification and recycling of farnesylcysteine. | 2007 | Plant J. | pmid:17425716 |
| Woodard B et al. | 3D-QSAR of fungal quorum-sensing inhibiting analogs of farnesol. | 2007 Mar-Apr | J Environ Sci Health B | pmid:17454380 |
| Navarathna DH et al. | Exogenous farnesol interferes with the normal progression of cytokine expression during candidiasis in a mouse model. | 2007 | Infect. Immun. | pmid:17517874 |
| Cheng AX et al. | The rice (E)-beta-caryophyllene synthase (OsTPS3) accounts for the major inducible volatile sesquiterpenes. | 2007 | Phytochemistry | pmid:17524436 |
| Zundelevich A et al. | Suppression of lung cancer tumor growth in a nude mouse model by the Ras inhibitor salirasib (farnesylthiosalicylic acid). | 2007 | Mol. Cancer Ther. | pmid:17541036 |
| Kuroda M et al. | Sesquiterpene farnesol as a competitive inhibitor of lipase activity of Staphylococcus aureus. | 2007 | FEMS Microbiol. Lett. | pmid:17559400 |
| Uppuluri P et al. | Farnesol-mediated inhibition of Candida albicans yeast growth and rescue by a diacylglycerol analogue. | 2007 | Yeast | pmid:17583896 |
| Yue W et al. | Mechanisms of acquired resistance to endocrine therapy in hormone-dependent breast cancer cells. | 2007 Aug-Sep | J. Steroid Biochem. Mol. Biol. | pmid:17616457 |
| Cugini C et al. | Farnesol, a common sesquiterpene, inhibits PQS production in Pseudomonas aeruginosa. | 2007 | Mol. Microbiol. | pmid:17640272 |
| da Silva Morais A et al. | Inhibition of the Ras oncoprotein reduces proliferation of hepatocytes in vitro and in vivo in rats. | 2008 | Clin. Sci. | pmid:17678500 |
| Rossignol T et al. | Transcriptional response of Candida parapsilosis following exposure to farnesol. | 2007 | Antimicrob. Agents Chemother. | pmid:17684006 |
| Zhang L and Hill RP | Hypoxia enhances metastatic efficiency in HT1080 fibrosarcoma cells by increasing cell survival in lungs, not cell adhesion and invasion. | 2007 | Cancer Res. | pmid:17699784 |
| Joo JH et al. | Farnesol-induced apoptosis in human lung carcinoma cells is coupled to the endoplasmic reticulum stress response. | 2007 | Cancer Res. | pmid:17699800 |
| Lee H et al. | Characterization of (E,E)-farnesol and its fatty acid esters from anal scent glands of nutria (Myocastor coypus) by gas chromatography-mass spectrometry and gas chromatography-infrared spectrometry. | 2007 | J Chromatogr A | pmid:17709112 |
| Marciano D et al. | Neuroprotective effects of the Ras inhibitor S-trans-trans-farnesylthiosalicylic acid, measured by diffusion-weighted imaging after traumatic brain injury in rats. | 2007 | J. Neurotrauma | pmid:17711399 |
| Dionigi CP et al. | Effects of farnesol and the off-flavor derivative geosmin on Streptomyces tendae. | 1991 | Appl. Environ. Microbiol. | pmid:1785920 |
| Haklai R et al. | Orally administered FTS (salirasib) inhibits human pancreatic tumor growth in nude mice. | 2008 | Cancer Chemother. Pharmacol. | pmid:17909812 |
| Zvibel I et al. | The effect of Ras inhibition on the proliferation, apoptosis and matrix metalloproteases activity in rat hepatic stellate cells. | 2008 | Dig. Dis. Sci. | pmid:17934818 |
| Cho T et al. | Transcriptional changes in Candida albicans Genes by both farnesol and high cell density at an early stage of morphogenesis in N-acetyl-D-glucosamine medium. | 2007 | Nihon Ishinkin Gakkai Zasshi | pmid:17975531 |
| Abbasnezhad H et al. | Two different mechanisms for adhesion of Gram-negative bacterium, Pseudomonas fluorescens LP6a, to an oil-water interface. | 2008 | Colloids Surf B Biointerfaces | pmid:17997081 |
| Shchepin R et al. | Influence of heterocyclic and oxime-containing farnesol analogs on quorum sensing and pathogenicity in Candida albicans. | 2008 | Bioorg. Med. Chem. | pmid:18037299 |
| Davis-Hanna A et al. | Farnesol and dodecanol effects on the Candida albicans Ras1-cAMP signalling pathway and the regulation of morphogenesis. | 2008 | Mol. Microbiol. | pmid:18078440 |
| Maher M et al. | Activation of TRPA1 by farnesyl thiosalicylic acid. | 2008 | Mol. Pharmacol. | pmid:18171730 |
| Golczak M et al. | Metabolic basis of visual cycle inhibition by retinoid and nonretinoid compounds in the vertebrate retina. | 2008 | J. Biol. Chem. | pmid:18195010 |
| Semighini CP et al. | Inhibition of Fusarium graminearum growth and development by farnesol. | 2008 | FEMS Microbiol. Lett. | pmid:18201191 |
| Blum R et al. | Inhibitors of chronically active ras: potential for treatment of human malignancies. | 2008 | Recent Pat Anticancer Drug Discov | pmid:18289122 |
| Teshima K and Kondo T | Analytical method for determination of allylic isoprenols in rat tissues by liquid chromatography/tandem mass spectrometry following chemical derivatization with 3-nitrophtalic anhydride. | 2008 | J Pharm Biomed Anal | pmid:18313250 |
| Tsangarakis C et al. | Zeolite NaY-promoted cyclization of farnesal: a short route to nanaimoal. | 2008 | J. Org. Chem. | pmid:18321121 |
| Weber K et al. | Secretion of E,E-farnesol and biofilm formation in eight different Candida species. | 2008 | Antimicrob. Agents Chemother. | pmid:18332168 |
| Shimomura K et al. | Homofarnesals: female sex attractant pheromone components of the southern cowpea weevil, Callosobruchus chinensis. | 2008 | J. Chem. Ecol. | pmid:18351422 |
| Rotblat B et al. | The Ras inhibitor farnesylthiosalicylic acid (Salirasib) disrupts the spatiotemporal localization of active Ras: a potential treatment for cancer. | 2008 | Meth. Enzymol. | pmid:18374183 |
| Lorek J et al. | Influence of farnesol on the morphogenesis of Aspergillus niger. | 2008 | J. Basic Microbiol. | pmid:18383232 |
| Marcuzzi A et al. | Natural isoprenoids are able to reduce inflammation in a mouse model of mevalonate kinase deficiency. | 2008 | Pediatr. Res. | pmid:18391837 |
| Chen CK et al. | The effect of mutation of F87 on the properties of CYP102A1-CYP4C7 chimeras: altered regiospecificity and substrate selectivity. | 2008 | J. Biol. Inorg. Chem. | pmid:18392864 |
| Joo JH and Jetten AM | NF-kappaB-dependent transcriptional activation in lung carcinoma cells by farnesol involves p65/RelA(Ser276) phosphorylation via the MEK-MSK1 signaling pathway. | 2008 | J. Biol. Chem. | pmid:18424438 |
| Kebaara BW et al. | Candida albicans Tup1 is involved in farnesol-mediated inhibition of filamentous-growth induction. | 2008 | Eukaryotic Cell | pmid:18424510 |
| McAlester G et al. | Signal-mediated interactions between Pseudomonas aeruginosa and Candida albicans. | 2008 | J. Med. Microbiol. | pmid:18436588 |
| Mor A et al. | N-Ras or K-Ras inhibition increases the number and enhances the function of Foxp3 regulatory T cells. | 2008 | Eur. J. Immunol. | pmid:18461565 |
| Duncan RE and Archer MC | Farnesol decreases serum triglycerides in rats: identification of mechanisms including up-regulation of PPARalpha and down-regulation of fatty acid synthase in hepatocytes. | 2008 | Lipids | pmid:18509688 |
| Zhao M et al. | Determination of salirasib (S-trans,trans-farnesylthiosalicylic acid) in human plasma using liquid chromatography-tandem mass spectrometry. | 2008 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:18534927 |
| Schleimer K et al. | Competition between native liver and graft in auxiliary liver transplantation in a rat model. | 2008 | Transplant. Proc. | pmid:18555091 |
| Au-Yeung KK et al. | Herbal isoprenols induce apoptosis in human colon cancer cells through transcriptional activation of PPARgamma. | 2008 | Cancer Invest. | pmid:18608213 |
| Geraldo IM et al. | Rapid antibacterial activity of 2 novel hand soaps: evaluation of the risk of development of bacterial resistance to the antibacterial agents. | 2008 | Infect Control Hosp Epidemiol | pmid:18616390 |
| Jahangir T and Sultana S | Benzo(a)pyrene-induced genotoxicity: attenuation by farnesol in a mouse model. | 2008 | J Enzyme Inhib Med Chem | pmid:18618320 |
| Muramatsu M et al. | Accumulation of prenyl alcohols by terpenoid biosynthesis inhibitors in various microorganisms. | 2008 | Appl. Microbiol. Biotechnol. | pmid:18636253 |