| MeSH term | MeSH ID | Detail |
|---|---|---|
| Adenocarcinoma | D000230 | 166 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Candidiasis, Oral | D002180 | 11 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Fibrosis | D005355 | 23 associated lipids |
| Glioblastoma | D005909 | 27 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
(e,z)-farnesol
(e,z)-farnesol is a lipid of Prenol Lipids (PR) class.
Cross Reference
There are no associated biomedical information in the current reference collection.
Current reference collection contains 3613 references associated with (e,z)-farnesol in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.
Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.
Here are additional resources we collected from PubChem and MeSH for (e,z)-farnesol
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with (e,z)-farnesol
PubChem Biomolecular Interactions and Pathways
All references with (e,z)-farnesol
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Anthony ML et al. | Inhibition of phosphatidylcholine biosynthesis following induction of apoptosis in HL-60 cells. | 1999 | J. Biol. Chem. | pmid:10391908 |
| Andres DA et al. | Rapid identification of cysteine-linked isoprenyl groups by metabolic labeling with [3H]farnesol and [3H]geranylgeraniol. | 1999 | Methods Mol. Biol. | pmid:10399149 |
| Dudler T and Gelb MH | Probing the role of H-Ras lipidation for signaling functions in Xenopus laevis oocytes. | 1999 | Methods Mol. Biol. | pmid:10399152 |
| Bifulco M et al. | Inhibition of farnesylation blocks growth but not differentiation in FRTL-5 thyroid cells. | 1999 | Biochimie | pmid:10401660 |
| Weisz B et al. | A new functional Ras antagonist inhibits human pancreatic tumor growth in nude mice. | 1999 | Oncogene | pmid:10353601 |
| Egozi Y et al. | Growth inhibition of ras-dependent tumors in nude mice by a potent ras-dislodging antagonist. | 1999 | Int. J. Cancer | pmid:10074926 |
| Fisher JE et al. | Alendronate mechanism of action: geranylgeraniol, an intermediate in the mevalonate pathway, prevents inhibition of osteoclast formation, bone resorption, and kinase activation in vitro. | 1999 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9874784 |
| Luft UC et al. | Farnesol blocks the L-type Ca2+ channel by targeting the alpha 1C subunit. | 1999 | Arterioscler. Thromb. Vasc. Biol. | pmid:10195923 |
| Roullet JB et al. | Modulation of neuronal voltage-gated calcium channels by farnesol. | 1999 | J. Biol. Chem. | pmid:10464274 |
| Gibbs BS et al. | Novel farnesol and geranylgeraniol analogues: A potential new class of anticancer agents directed against protein prenylation. | 1999 | J. Med. Chem. | pmid:10508429 |
| Ghosh PM et al. | Role of RhoA activation in the growth and morphology of a murine prostate tumor cell line. | 1999 | Oncogene | pmid:10435593 |
| Benford HL et al. | Farnesol and geranylgeraniol prevent activation of caspases by aminobisphosphonates: biochemical evidence for two distinct pharmacological classes of bisphosphonate drugs. | 1999 | Mol. Pharmacol. | pmid:10385693 |
| Niv H et al. | Membrane interactions of a constitutively active GFP-Ki-Ras 4B and their role in signaling. Evidence from lateral mobility studies. | 1999 | J. Biol. Chem. | pmid:9880539 |
| Weissmann N et al. | Evidence for a role of protein kinase C in hypoxic pulmonary vasoconstriction. | 1999 | Am. J. Physiol. | pmid:9887060 |
| Hanley K et al. | Fetal epidermal differentiation and barrier development In vivo is accelerated by nuclear hormone receptor activators. | 1999 | J. Invest. Dermatol. | pmid:10571735 |
| Goodwin TE et al. | African elephant sesquiterpenes. | 1999 | J. Nat. Prod. | pmid:10579877 |
| Machida K and Tanaka T | Farnesol-induced generation of reactive oxygen species dependent on mitochondrial transmembrane potential hyperpolarization mediated by F(0)F(1)-ATPase in yeast. | 1999 | FEBS Lett. | pmid:10580101 |
| Hirohata S et al. | Inhibition of human B cell activation by a novel nonsteroidal anti-inflammatory drug, indometacin famesil. | 1999 | Immunopharmacology | pmid:10598881 |
| Jansen B et al. | Novel Ras antagonist blocks human melanoma growth. | 1999 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10570191 |
| Elad G et al. | Targeting of K-Ras 4B by S-trans,trans-farnesyl thiosalicylic acid. | 1999 | Biochim. Biophys. Acta | pmid:10590312 |
| Reif S et al. | The Ras antagonist, farnesylthiosalicylic acid (FTS), inhibits experimentally-induced liver cirrhosis in rats. | 1999 | J. Hepatol. | pmid:10604579 |
| Corsini A et al. | Incorporation of radiolabeled prenyl alcohols and their analogs into mammalian cell proteins. A useful tool for studying protein prenylation. | 1999 | Methods Mol. Biol. | pmid:10399150 |
| Hartmann MA et al. | Metabolism of farnesyl diphosphate in tobacco BY-2 cells treated with squalestatin. | 2000 | Biochem. Soc. Trans. | pmid:11171211 |
| Beedle AM and Zamponi GW | Block of voltage-dependent calcium channels by aliphatic monoamines. | 2000 | Biophys. J. | pmid:10866952 |
| Mo H et al. | Farnesyl anthranilate suppresses the growth, in vitro and in vivo, of murine B16 melanomas. | 2000 | Cancer Lett. | pmid:10936674 |
| Toró A et al. | Transannular Diels-Alder studies on the asymmetric total synthesis of chatancin: the pyranophane approach. | 2000 | Org. Lett. | pmid:10964353 |
| Yang W et al. | Protein farnesylation is critical for maintaining normal cell morphology and canavanine resistance in Schizosaccharomyces pombe. | 2000 | J. Biol. Chem. | pmid:10617635 |
| Hanley K et al. | Farnesol stimulates differentiation in epidermal keratinocytes via PPARalpha. | 2000 | J. Biol. Chem. | pmid:10753967 |
| Bringmann A et al. | Farnesol modulates membrane currents in human retinal glial cells. | 2000 | J. Neurosci. Res. | pmid:11054809 |
| Halaschek-Wiener J et al. | A novel Ras antagonist regulates both oncogenic Ras and the tumor suppressor p53 in colon cancer cells. | 2000 | Mol. Med. | pmid:11055588 |
| Xie H et al. | Synthesis and biological evaluation of the geometric farnesylated analogues of the a-factor mating peptide of Saccharomyces cerevisiae. | 2000 | J. Org. Chem. | pmid:11112575 |
| Eskens FA et al. | Farnesyl transferase inhibitors: current developments and future perspectives. | 2000 | Cancer Treat. Rev. | pmid:11006134 |
| Kloog Y and Cox AD | RAS inhibitors: potential for cancer therapeutics. | 2000 | Mol Med Today | pmid:11006529 |
| Hemmerlin A and Bach TJ | Farnesol-induced cell death and stimulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity in tobacco cv bright yellow-2 cells. | 2000 | Plant Physiol. | pmid:10938345 |
| Mussoni L et al. | Fluvastatin inhibits basal and stimulated plasminogen activator inhibitor 1, but induces tissue type plasminogen activator in cultured human endothelial cells. | 2000 | Thromb. Haemost. | pmid:10928471 |
| Rioja A et al. | Preferential induction of apoptosis of leukaemic cells by farnesol. | 2000 | FEBS Lett. | pmid:10675556 |
| Hemmer W et al. | Axillary dermatitis from farnesol in a deodorant. | 2000 | Contact Derm. | pmid:10727172 |
| Rosado JA and Sage SO | Farnesylcysteine analogues inhibit store-regulated Ca2+ entry in human platelets: evidence for involvement of small GTP-binding proteins and actin cytoskeleton. | 2000 | Biochem. J. | pmid:10727417 |
| Flach J et al. | The mevalonate/isoprenoid pathway inhibitor apomine (SR-45023A) is antiproliferative and induces apoptosis similar to farnesol. | 2000 | Biochem. Biophys. Res. Commun. | pmid:10733934 |
| Cheng QF et al. | Effect of perillic acid, a putative isoprenylation inhibitor, on the cultured rat lens. | 2001 | Exp. Eye Res. | pmid:11446774 |
| Sperry AE and Sen SE | Farnesol oxidation in insects: evidence that the biosynthesis of insect juvenile hormone is mediated by a specific alcohol oxidase. | 2001 | Insect Biochem. Mol. Biol. | pmid:11164339 |
| Villegas LF et al. | (+)-epi-Alpha-bisabolol [correction of bisbolol] is the wound-healing principle of Peperomia galioides: investigation of the in vivo wound-healing activity of related terpenoids. | 2001 | J. Nat. Prod. | pmid:11678668 |
| Mizukami Y et al. | Requirement of c-jun N-terminal kinase for apoptotic cell death induced by farnesyltransferase inhibitor, farnesylamine, in human pancreatic cancer cells. | 2001 | Biochem. Biophys. Res. Commun. | pmid:11594773 |
| Karussis D et al. | The Ras-pathway inhibitor, S-trans-trans-farnesylthiosalicylic acid, suppresses experimental allergic encephalomyelitis. | 2001 | J. Neuroimmunol. | pmid:11694313 |
| Kim SY et al. | Inhibition effect of new farnesol derivatives on all-trans-retinoic acid metabolism. | 2001 | Metab. Clin. Exp. | pmid:11699057 |
| Sari R et al. | Impairment by lovastatin of neural relaxation of the rabbit sphincter of Oddi. | 2001 | Eur. J. Pharmacol. | pmid:11734192 |
| Rakhit RD et al. | Role of G proteins and modulation of p38 MAPK activation in the protection by nitric oxide against ischemia-reoxygenation injury. | 2001 | Biochem. Biophys. Res. Commun. | pmid:11527399 |
| Nah J et al. | Partial characterization of farnesyl and geranylgeranyl diphosphatases induced in rice seedlings by UV-C irradiation. | 2001 | Plant Cell Physiol. | pmid:11522913 |
| Katzav A et al. | Treatment of MRL/lpr mice, a genetic autoimmune model, with the Ras inhibitor, farnesylthiosalicylate (FTS). | 2001 | Clin. Exp. Immunol. | pmid:11737078 |
| Clausen VA et al. | Stereochemical analysis of the reaction catalyzed by human protein geranylgeranyl transferase. | 2001 | Biochemistry | pmid:11300771 |
| Rosado JA and Sage SO | Role of the ERK pathway in the activation of store-mediated calcium entry in human platelets. | 2001 | J. Biol. Chem. | pmid:11278479 |
| Wright MM et al. | Uncoupling farnesol-induced apoptosis from its inhibition of phosphatidylcholine synthesis. | 2001 | J. Biol. Chem. | pmid:11306571 |
| Daily D et al. | Glutaredoxin protects cerebellar granule neurons from dopamine-induced apoptosis by dual activation of the ras-phosphoinositide 3-kinase and jun n-terminal kinase pathways. | 2001 | J. Biol. Chem. | pmid:11290748 |
| Hornby JM et al. | Quorum sensing in the dimorphic fungus Candida albicans is mediated by farnesol. | 2001 | Appl. Environ. Microbiol. | pmid:11425711 |
| Tschantz WR et al. | Lysosomal prenylcysteine lyase is a FAD-dependent thioether oxidase. | 2001 | J. Biol. Chem. | pmid:11078725 |
| Koo H et al. | Effects of apigenin and tt-farnesol on glucosyltransferase activity, biofilm viability and caries development in rats. | 2002 | Oral Microbiol. Immunol. | pmid:12485324 |
| Schnee C et al. | The maize gene terpene synthase 1 encodes a sesquiterpene synthase catalyzing the formation of (E)-beta-farnesene, (E)-nerolidol, and (E,E)-farnesol after herbivore damage. | 2002 | Plant Physiol. | pmid:12481088 |
| Hamada M et al. | Farnesylpyridinium, an analog of isoprenoid farnesol, induces apoptosis but suppresses apoptotic body formation in human promyelocytic leukemia cells. | 2002 | FEBS Lett. | pmid:11943160 |
| Gana-Weisz M et al. | The Ras inhibitor S-trans,trans-farnesylthiosalicylic acid chemosensitizes human tumor cells without causing resistance. | 2002 | Clin. Cancer Res. | pmid:11839677 |
| Smalley KS and Eisen TG | Farnesyl thiosalicylic acid inhibits the growth of melanoma cells through a combination of cytostatic and pro-apoptotic effects. | 2002 | Int. J. Cancer | pmid:11920610 |
| Teal PE | Effects of allatotropin and allatostatin on in vitro production of juvenile hormones by the corpora allata of virgin females of the moths of Heliothis virescens and Manduca sexta. | 2002 | Peptides | pmid:11897385 |
| Meinhardt G et al. | Effect of novel modulators of protein kinase C activity upon chemotherapy-induced differentiation and apoptosis in myeloid leukemic cells. | 2002 | Anticancer Drugs | pmid:12187329 |
| Chakrabarti D et al. | Protein farnesyltransferase and protein prenylation in Plasmodium falciparum. | 2002 | J. Biol. Chem. | pmid:12194969 |
| Akiyama H et al. | Actions of farnesol and xylitol against Staphylococcus aureus. | 2002 | Chemotherapy | pmid:12138327 |
| Takahashi N et al. | Dual action of isoprenols from herbal medicines on both PPARgamma and PPARalpha in 3T3-L1 adipocytes and HepG2 hepatocytes. | 2002 | FEBS Lett. | pmid:11943173 |
| George J et al. | Functional inhibition of Ras by S-trans,trans-farnesyl thiosalicylic acid attenuates atherosclerosis in apolipoprotein E knockout mice. | 2002 | Circulation | pmid:12021230 |
| Raner GM et al. | Farnesol as an inhibitor and substrate for rabbit liver microsomal P450 enzymes. | 2002 | Biochem. Biophys. Res. Commun. | pmid:12054554 |
| Lagace TA et al. | Caspase processing and nuclear export of CTP:phosphocholine cytidylyltransferase alpha during farnesol-induced apoptosis. | 2002 | Mol. Cell. Biol. | pmid:12052891 |
| Frenkel J et al. | Lack of isoprenoid products raises ex vivo interleukin-1beta secretion in hyperimmunoglobulinemia D and periodic fever syndrome. | 2002 | Arthritis Rheum. | pmid:12384940 |
| Ludolph B et al. | Solution- and solid-phase synthesis of the polybasic lipid-modified C termini of Rho A and K-Ras 4B. | 2002 | Chembiochem | pmid:12210992 |
| Ramage G et al. | Inhibition of Candida albicans biofilm formation by farnesol, a quorum-sensing molecule. | 2002 | Appl. Environ. Microbiol. | pmid:12406738 |
| Kato N et al. | Treatment of the chronic inflammation in peripheral target tissue improves the crushed nerve recovery in the rat: histopathological assessment of the nerve recovery. | 2002 | J. Neurol. Sci. | pmid:12220695 |
| Ward SM et al. | TGFbeta regulates the expression of G alpha(i2) via an effect on the localization of ras. | 2002 | J. Mol. Cell. Cardiol. | pmid:12392895 |
| Goodwin TE et al. | African elephant sesquiterpenes. II. Identification and synthesis of new derivatives of 2,3-dihydrofarnesol. | 2002 | J. Nat. Prod. | pmid:12350155 |
| Winn LM and Wells PG | Evidence for Ras-dependent signal transduction in phenytoin teratogenicity. | 2002 | Toxicol. Appl. Pharmacol. | pmid:12460742 |
| Du Y and Wiemer DF | Alpha-phosphono lactone analogues of farnesyl pyrophosphate: an asymmetric synthesis via ring-closing metathesis. | 2002 | J. Org. Chem. | pmid:12153272 |
| Radetich B and Corey EJ | A general stereocontrolled, convergent synthesis of oligoprenols that parallels the biosynthetic pathway. | 2002 | J. Am. Chem. Soc. | pmid:11890779 |
| Lochnit G and Geyer R | Evidence for the presence of the Kennedy and Bremer- Greenberg pathways in Caenorhabditis elegans. | 2003 | Acta Biochim. Pol. | pmid:14740010 |
| Sakata T et al. | Chemical ecology of oribatid mites III. Chemical composition of oil gland exudates from two oribatid mites, Trhypochthoniellus sp. and Trhypochthonius japonicus (Acari: Trhypochthoniidae). | 2003 | Exp. Appl. Acarol. | pmid:14635814 |
| Granshaw T et al. | Circadian rhythms in Neurospora crassa: farnesol or geraniol allow expression of rhythmicity in the otherwise arrhythmic strains frq10, wc-1, and wc-2. | 2003 | J. Biol. Rhythms | pmid:12932081 |
| Koo H et al. | Inhibition of Streptococcus mutans biofilm accumulation and polysaccharide production by apigenin and tt-farnesol. | 2003 | J. Antimicrob. Chemother. | pmid:14563892 |
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| Sen SE et al. | Juvenile hormone biosynthesis in moths: synthesis and evaluation of farnesol homologs as alternate substrates of farnesol oxidase. | 2003 | Insect Biochem. Mol. Biol. | pmid:12770578 |
| Katzav A et al. | Inhibition of ras by farnesylthiosalicylate significantly reduces the levels of autoantibodies in two animal models of the antiphospholipid syndrome. | 2003 | Immunobiology | pmid:12638903 |
| Shohami E et al. | The Ras inhibitor S-trans, trans-farnesylthiosalicylic acid exerts long-lasting neuroprotection in a mouse closed head injury model. | 2003 | J. Cereb. Blood Flow Metab. | pmid:12796721 |
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| Clarke HC et al. | Ras antagonist farnesylthiosalicylic acid (FTS) reduces glomerular cellular proliferation and macrophage number in rat thy-1 nephritis. | 2003 | J. Am. Soc. Nephrol. | pmid:12660318 |
| Jones TH et al. | Farnesylamine from the ant Monomorium fieldi Forel. | 2003 | J. Nat. Prod. | pmid:12662086 |
| Smalley KS and Eisen TG | Farnesyl transferase inhibitor SCH66336 is cytostatic, pro-apoptotic and enhances chemosensitivity to cisplatin in melanoma cells. | 2003 | Int. J. Cancer | pmid:12673674 |
| Song L | Detection of farnesyl diphosphate accumulation in yeast ERG9 mutants. | 2003 | Anal. Biochem. | pmid:12758256 |
| Halaschek-Wiener J et al. | Farnesyl thiosalicylic acid chemosensitizes human melanoma in vivo. | 2003 | J. Invest. Dermatol. | pmid:12535206 |
| Zoccarato F et al. | The adenosine inhibition of glutamate exocytosis in synaptosomes is removed by the collapse of the vesicle-cytosol deltapH plus the opening of farnesol-sensitive Ca(2+) channels. | 2003 | Cell Calcium | pmid:12618148 |
| Hiyoshi H et al. | Squalene synthase inhibitors suppress triglyceride biosynthesis through the farnesol pathway in rat hepatocytes. | 2003 | J. Lipid Res. | pmid:12518031 |
| Töyräs A et al. | Inhibition of mevalonate pathway is involved in alendronate-induced cell growth inhibition, but not in cytokine secretion from macrophages in vitro. | 2003 | Eur J Pharm Sci | pmid:12885386 |
| Houten SM et al. | Isoprenoid biosynthesis in hereditary periodic fever syndromes and inflammation. | 2003 | Cell. Mol. Life Sci. | pmid:12861380 |
| Li X et al. | New polyoxygenated farnesylcyclohexenones, deacetoxyyanuthone A and its hydro derivative from the marine-derived fungus Penicillium sp. | 2003 | J. Nat. Prod. | pmid:14640527 |
| McAnally JA et al. | Farnesyl-O-acetylhydroquinone and geranyl-O-acetylhydroquinone suppress the proliferation of murine B16 melanoma cells, human prostate and colon adenocarcinoma cells, human lung carcinoma cells, and human leukemia cells. | 2003 | Cancer Lett. | pmid:14643448 |
| Grossman R et al. | Increase in peripheral benzodiazepine receptors and loss of glutamate NMDA receptors in a mouse model of closed head injury: a quantitative autoradiographic study. | 2003 | Neuroimage | pmid:14683703 |