(e,z)-farnesol

(e,z)-farnesol is a lipid of Prenol Lipids (PR) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 3613 references associated with (e,z)-farnesol in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for (e,z)-farnesol

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (e,z)-farnesol

MeSH term MeSH ID Detail
Adenocarcinoma D000230 166 associated lipids
Body Weight D001835 333 associated lipids
Candidiasis, Oral D002180 11 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Edema D004487 152 associated lipids
Fibrosis D005355 23 associated lipids
Glioblastoma D005909 27 associated lipids
Glioma D005910 112 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hypergammaglobulinemia D006942 9 associated lipids
Insulin Resistance D007333 99 associated lipids
Lung Neoplasms D008175 171 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Nephritis D009393 19 associated lipids
Neurilemmoma D009442 10 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Osteosarcoma D012516 50 associated lipids
Thyroid Neoplasms D013964 33 associated lipids
Per page 10 20 50 | Total 23

PubChem Biomolecular Interactions and Pathways

All references with (e,z)-farnesol

Download all related citations
Per page 10 20 50 100 | Total 813
Authors Title Published Journal PubMed Link
Chana RS and Brunskill NJ Thiazolidinediones inhibit albumin uptake by proximal tubular cells through a mechanism independent of peroxisome proliferator activated receptor gamma. 2006 Am. J. Nephrol. pmid:16508249
Khalil AA et al. Isolation and characterization of a monoamine oxidase B selective inhibitor from tobacco smoke. 2006 Bioorg. Med. Chem. pmid:16458520
Song L A soluble form of phosphatase in Saccharomyces cerevisiae capable of converting farnesyl diphosphate into E,E-farnesol. 2006 Appl. Biochem. Biotechnol. pmid:16484724
Xie J et al. Microparticles developed by electrohydrodynamic atomization for the local delivery of anticancer drug to treat C6 glioma in vitro. 2006 Biomaterials pmid:16490248
Jones G et al. The retinoid-X receptor ortholog, ultraspiracle, binds with nanomolar affinity to an endogenous morphogenetic ligand. 2006 FEBS J. pmid:17064257
Beiner ME et al. Ras antagonist inhibits growth and chemosensitizes human epithelial ovarian cancer cells. 2006 Jan-Feb Int. J. Gynecol. Cancer pmid:16515591
Kuroda M et al. Sesquiterpene farnesol inhibits recycling of the C55 lipid carrier of the murein monomer precursor contributing to increased susceptibility to beta-lactams in methicillin-resistant Staphylococcus aureus. 2007 J. Antimicrob. Chemother. pmid:17242033
Nokhodchi A et al. The effect of terpene concentrations on the skin penetration of diclofenac sodium. 2007 Int J Pharm pmid:17174049
Shapira S et al. The tumor suppressor neurofibromin confers sensitivity to apoptosis by Ras-dependent and Ras-independent pathways. 2007 Cell Death Differ. pmid:17096025
Cho T et al. Transcriptional changes in Candida albicans Genes by both farnesol and high cell density at an early stage of morphogenesis in N-acetyl-D-glucosamine medium. 2007 Nihon Ishinkin Gakkai Zasshi pmid:17975531
Henriques M et al. Effect of farnesol on Candida dubliniensis morphogenesis. 2007 Lett. Appl. Microbiol. pmid:17257261
Navarathna DH et al. Effect of farnesol on a mouse model of systemic candidiasis, determined by use of a DPP3 knockout mutant of Candida albicans. 2007 Infect. Immun. pmid:17283095
Kuroda M et al. Sesquiterpene farnesol as a competitive inhibitor of lipase activity of Staphylococcus aureus. 2007 FEMS Microbiol. Lett. pmid:17559400
Zundelevich A et al. Suppression of lung cancer tumor growth in a nude mouse model by the Ras inhibitor salirasib (farnesylthiosalicylic acid). 2007 Mol. Cancer Ther. pmid:17541036
Navarathna DH et al. Exogenous farnesol interferes with the normal progression of cytokine expression during candidiasis in a mouse model. 2007 Infect. Immun. pmid:17517874
Uppuluri P et al. Farnesol-mediated inhibition of Candida albicans yeast growth and rescue by a diacylglycerol analogue. 2007 Yeast pmid:17583896
Crowell DN et al. Arabidopsis thaliana plants possess a specific farnesylcysteine lyase that is involved in detoxification and recycling of farnesylcysteine. 2007 Plant J. pmid:17425716
Blum R et al. Gene expression signature of human cancer cell lines treated with the ras inhibitor salirasib (S-farnesylthiosalicylic acid). 2007 Cancer Res. pmid:17409441
Rossignol T et al. Transcriptional response of Candida parapsilosis following exposure to farnesol. 2007 Antimicrob. Agents Chemother. pmid:17684006
Cugini C et al. Farnesol, a common sesquiterpene, inhibits PQS production in Pseudomonas aeruginosa. 2007 Mol. Microbiol. pmid:17640272
Dumitru R et al. In vivo and in vitro anaerobic mating in Candida albicans. 2007 Eukaryotic Cell pmid:17259544
Shintre MS et al. Evaluation of an alcohol-based surgical hand disinfectant containing a synergistic combination of farnesol and benzethonium chloride for immediate and persistent activity against resident hand flora of volunteers and with a novel in vitro pig skin model. 2007 Infect Control Hosp Epidemiol pmid:17265401
Zhang L and Hill RP Hypoxia enhances metastatic efficiency in HT1080 fibrosarcoma cells by increasing cell survival in lungs, not cell adhesion and invasion. 2007 Cancer Res. pmid:17699784
Joo JH et al. Farnesol-induced apoptosis in human lung carcinoma cells is coupled to the endoplasmic reticulum stress response. 2007 Cancer Res. pmid:17699800
Lee H et al. Characterization of (E,E)-farnesol and its fatty acid esters from anal scent glands of nutria (Myocastor coypus) by gas chromatography-mass spectrometry and gas chromatography-infrared spectrometry. 2007 J Chromatogr A pmid:17709112
Marciano D et al. Neuroprotective effects of the Ras inhibitor S-trans-trans-farnesylthiosalicylic acid, measured by diffusion-weighted imaging after traumatic brain injury in rats. 2007 J. Neurotrauma pmid:17711399
Lombardi L et al. Circadian rhythms in Neurospora crassa: clock mutant effects in the absence of a frq-based oscillator. 2007 Genetics pmid:17237512
Cheng AX et al. The rice (E)-beta-caryophyllene synthase (OsTPS3) accounts for the major inducible volatile sesquiterpenes. 2007 Phytochemistry pmid:17524436
Wiseman DA et al. Cell cycle arrest by the isoprenoids perillyl alcohol, geraniol, and farnesol is mediated by p21(Cip1) and p27(Kip1) in human pancreatic adenocarcinoma cells. 2007 J. Pharmacol. Exp. Ther. pmid:17138864
Fairn GD et al. A chemogenomic screen in Saccharomyces cerevisiae uncovers a primary role for the mitochondria in farnesol toxicity and its regulation by the Pkc1 pathway. 2007 J. Biol. Chem. pmid:17164236
Cetin A et al. Angiotensin II-induced MAPK phosphorylation mediated by Ras and/or phospholipase C-dependent phosphorylations but not by protein kinase C phosphorylation in cultured rat vascular smooth muscle cells. 2007 Pharmacology pmid:17135774
Hasmim M et al. Zoledronate inhibits endothelial cell adhesion, migration and survival through the suppression of multiple, prenylation-dependent signaling pathways. 2007 J. Thromb. Haemost. pmid:17059425
Yue W et al. Mechanisms of acquired resistance to endocrine therapy in hormone-dependent breast cancer cells. 2007 Aug-Sep J. Steroid Biochem. Mol. Biol. pmid:17616457
Woodard B et al. 3D-QSAR of fungal quorum-sensing inhibiting analogs of farnesol. 2007 Mar-Apr J Environ Sci Health B pmid:17454380
Mor A et al. N-Ras or K-Ras inhibition increases the number and enhances the function of Foxp3 regulatory T cells. 2008 Eur. J. Immunol. pmid:18461565
Davis-Hanna A et al. Farnesol and dodecanol effects on the Candida albicans Ras1-cAMP signalling pathway and the regulation of morphogenesis. 2008 Mol. Microbiol. pmid:18078440
Abbasnezhad H et al. Two different mechanisms for adhesion of Gram-negative bacterium, Pseudomonas fluorescens LP6a, to an oil-water interface. 2008 Colloids Surf B Biointerfaces pmid:17997081
Haklai R et al. Orally administered FTS (salirasib) inhibits human pancreatic tumor growth in nude mice. 2008 Cancer Chemother. Pharmacol. pmid:17909812
Zvibel I et al. The effect of Ras inhibition on the proliferation, apoptosis and matrix metalloproteases activity in rat hepatic stellate cells. 2008 Dig. Dis. Sci. pmid:17934818
Journe F et al. Farnesol, a mevalonate pathway intermediate, stimulates MCF-7 breast cancer cell growth through farnesoid-X-receptor-mediated estrogen receptor activation. 2008 Breast Cancer Res. Treat. pmid:17333335
da Silva Morais A et al. Inhibition of the Ras oncoprotein reduces proliferation of hepatocytes in vitro and in vivo in rats. 2008 Clin. Sci. pmid:17678500
Shchepin R et al. Influence of heterocyclic and oxime-containing farnesol analogs on quorum sensing and pathogenicity in Candida albicans. 2008 Bioorg. Med. Chem. pmid:18037299
Semighini CP et al. Inhibition of Fusarium graminearum growth and development by farnesol. 2008 FEMS Microbiol. Lett. pmid:18201191
Golczak M et al. Metabolic basis of visual cycle inhibition by retinoid and nonretinoid compounds in the vertebrate retina. 2008 J. Biol. Chem. pmid:18195010
Maher M et al. Activation of TRPA1 by farnesyl thiosalicylic acid. 2008 Mol. Pharmacol. pmid:18171730
Weber K et al. Secretion of E,E-farnesol and biofilm formation in eight different Candida species. 2008 Antimicrob. Agents Chemother. pmid:18332168
Teshima K and Kondo T Analytical method for determination of allylic isoprenols in rat tissues by liquid chromatography/tandem mass spectrometry following chemical derivatization with 3-nitrophtalic anhydride. 2008 J Pharm Biomed Anal pmid:18313250
Blum R et al. Inhibitors of chronically active ras: potential for treatment of human malignancies. 2008 Recent Pat Anticancer Drug Discov pmid:18289122
Joo JH and Jetten AM NF-kappaB-dependent transcriptional activation in lung carcinoma cells by farnesol involves p65/RelA(Ser276) phosphorylation via the MEK-MSK1 signaling pathway. 2008 J. Biol. Chem. pmid:18424438
Kebaara BW et al. Candida albicans Tup1 is involved in farnesol-mediated inhibition of filamentous-growth induction. 2008 Eukaryotic Cell pmid:18424510

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