(e,z)-farnesol

(e,z)-farnesol is a lipid of Prenol Lipids (PR) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 3613 references associated with (e,z)-farnesol in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for (e,z)-farnesol

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (e,z)-farnesol

MeSH term MeSH ID Detail
Adenocarcinoma D000230 166 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Lung Neoplasms D008175 171 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Osteosarcoma D012516 50 associated lipids
Glioma D005910 112 associated lipids
Per page 10 20 50 | Total 23

PubChem Biomolecular Interactions and Pathways

All references with (e,z)-farnesol

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Per page 10 20 50 100 | Total 813
Authors Title Published Journal PubMed Link
Ivanov SS et al. Lipidation by the host prenyltransferase machinery facilitates membrane localization of Legionella pneumophila effector proteins. 2010 J. Biol. Chem. pmid:20813839
Levy R et al. Galectin-3 promotes chronic activation of K-Ras and differentiation block in malignant thyroid carcinomas. 2010 Mol. Cancer Ther. pmid:20682656
Charette N et al. Salirasib inhibits the growth of hepatocarcinoma cell lines in vitro and tumor growth in vivo through ras and mTOR inhibition. 2010 Mol. Cancer pmid:20860815
Bhandari J et al. Identification of a novel abscisic acid-regulated farnesol dehydrogenase from Arabidopsis. 2010 Plant Physiol. pmid:20807998
Chen CK et al. Scanning chimeragenesis: the approach used to change the substrate selectivity of fatty acid monooxygenase CYP102A1 to that of terpene omega-hydroxylase CYP4C7. 2010 J. Biol. Inorg. Chem. pmid:19727859
Ghosh S et al. Candida albicans cell wall components and farnesol stimulate the expression of both inflammatory and regulatory cytokines in the murine RAW264.7 macrophage cell line. 2010 FEMS Immunol. Med. Microbiol. pmid:20618847
Cugini C et al. Candida albicans-produced farnesol stimulates Pseudomonas quinolone signal production in LasR-defective Pseudomonas aeruginosa strains. 2010 Microbiology (Reading, Engl.) pmid:20656785
Weber K et al. The quorum-sensing molecule E,E-farnesol--its variable secretion and its impact on the growth and metabolism of Candida species. 2010 Yeast pmid:20641010
Doan K et al. In vivo and in vitro skin absorption of lipophilic compounds, dibutyl phthalate, farnesol and geraniol in the hairless guinea pig. 2010 Food Chem. Toxicol. pmid:19747520
Chagas CE et al. Farnesol inhibits cell proliferation and induces apoptosis after partial hepatectomy in rats. 2009 Sep-Oct Acta Cir Bras pmid:19851690
Song L Recovery of E,E-farnesol from cultures of yeast erg9 mutants: extraction with polymeric beads and purification by normal-phase chromatography. 2009 Jul-Aug Biotechnol. Prog. pmid:19569196
Cushion MT et al. Biofilm formation by Pneumocystis spp. 2009 Eukaryotic Cell pmid:18820078
Rennemeier C et al. Microbial quorum-sensing molecules induce acrosome loss and cell death in human spermatozoa. 2009 Infect. Immun. pmid:19687207
Banfi C et al. Proteomic analysis of human low-density lipoprotein reveals the presence of prenylcysteine lyase, a hydrogen peroxide-generating enzyme. 2009 Proteomics pmid:19253276
Koo H and Jeon JG Naturally occurring molecules as alternative therapeutic agents against cariogenic biofilms. 2009 Adv. Dent. Res. pmid:19717411
Gomes FI et al. Effect of farnesol on planktonic and biofilm cells of Staphylococcus epidermidis. 2009 Curr. Microbiol. pmid:19365686
Shirtliff ME et al. Farnesol-induced apoptosis in Candida albicans. 2009 Antimicrob. Agents Chemother. pmid:19364863
Chen F et al. Tooth-binding micelles for dental caries prevention. 2009 Antimicrob. Agents Chemother. pmid:19704121
Goldberg L et al. New derivatives of farnesylthiosalicylic acid (salirasib) for cancer treatment: farnesylthiosalicylamide inhibits tumor growth in nude mice models. 2009 J. Med. Chem. pmid:19072665
Ohto C et al. Prenyl alcohol production by expression of exogenous isopentenyl diphosphate isomerase and farnesyl diphosphate synthase genes in Escherichia coli. 2009 Biosci. Biotechnol. Biochem. pmid:19129660
Décanis N et al. Farnesol promotes epithelial cell defense against Candida albicans through Toll-like receptor 2 expression, interleukin-6 and human beta-defensin 2 production. 2009 Cytokine pmid:19121950
Rhome R and Del Poeta M Lipid signaling in pathogenic fungi. 2009 Annu. Rev. Microbiol. pmid:19450140
Chaudhary SC et al. Chemopreventive effect of farnesol on DMBA/TPA-induced skin tumorigenesis: involvement of inflammation, Ras-ERK pathway and apoptosis. 2009 Life Sci. pmid:19470390
Kraitzer A et al. Novel farnesylthiosalicylate (FTS)-eluting composite structures. 2009 Eur J Pharm Sci pmid:19491026
Mor A et al. Ras inhibition increases the frequency and function of regulatory T cells and attenuates type-1 diabetes in non-obese diabetic mice. 2009 Eur. J. Pharmacol. pmid:19527709
Muramatsu M et al. Alkaline pH enhances farnesol production by Saccharomyces cerevisiae. 2009 J. Biosci. Bioeng. pmid:19577192
Abe S et al. Suppression of anti-Candida activity of macrophages by a quorum-sensing molecule, farnesol, through induction of oxidative stress. 2009 Microbiol. Immunol. pmid:19493200
Derengowski LS et al. Antimicrobial effect of farnesol, a Candida albicans quorum sensing molecule, on Paracoccidioides brasiliensis growth and morphogenesis. 2009 Ann. Clin. Microbiol. Antimicrob. pmid:19402910
Rodríguez C et al. Statins normalize vascular lysyl oxidase down-regulation induced by proatherogenic risk factors. 2009 Cardiovasc. Res. pmid:19406911
Pando R et al. Ras inhibition attenuates myocardial ischemia-reperfusion injury. 2009 Biochem. Pharmacol. pmid:19426696
Schneider-Merck T et al. The Ras inhibitor farnesylthiosalicyclic acid (FTS) prevents nodule formation and development of preneoplastic foci of altered hepatocytes in rats. 2009 Eur. J. Cancer pmid:19427195
Unnanuntana A et al. The effects of farnesol on Staphylococcus aureus biofilms and osteoblasts. An in vitro study. 2009 J Bone Joint Surg Am pmid:19884443
Mayoral JG et al. NADP+-dependent farnesol dehydrogenase, a corpora allata enzyme involved in juvenile hormone synthesis. 2009 Proc. Natl. Acad. Sci. U.S.A. pmid:19940247
Langford ML et al. Cellular interactions of farnesol, a quorum-sensing molecule produced by Candida albicans. 2009 Future Microbiol pmid:19995193
Jeon JG et al. Influences of naturally occurring agents in combination with fluoride on gene expression and structural organization of Streptococcus mutans in biofilms. 2009 BMC Microbiol. pmid:19863808
Raptis C et al. Acid-catalyzed cyclization of terpenes under homogeneous and heterogeneous conditions as probed through stereoisotopic studies: a concerted process with competing preorganized chair and boat transition states. 2009 Chemistry pmid:19780112
Xiao Y et al. A two-component female-produced pheromone of the spider Pholcus beijingensis. 2009 J. Chem. Ecol. pmid:19579045
Duncan RE and Archer MC Farnesol decreases serum triglycerides in rats: identification of mechanisms including up-regulation of PPARalpha and down-regulation of fatty acid synthase in hepatocytes. 2008 Lipids pmid:18509688
Zhao M et al. Determination of salirasib (S-trans,trans-farnesylthiosalicylic acid) in human plasma using liquid chromatography-tandem mass spectrometry. 2008 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:18534927
Mor A et al. N-Ras or K-Ras inhibition increases the number and enhances the function of Foxp3 regulatory T cells. 2008 Eur. J. Immunol. pmid:18461565
Savoldi M et al. Farnesol induces the transcriptional accumulation of the Aspergillus nidulans Apoptosis-Inducing Factor (AIF)-like mitochondrial oxidoreductase. 2008 Mol. Microbiol. pmid:18681941
Kotti T et al. Biphasic requirement for geranylgeraniol in hippocampal long-term potentiation. 2008 Proc. Natl. Acad. Sci. U.S.A. pmid:18685105
Au-Yeung KK et al. Herbal isoprenols induce apoptosis in human colon cancer cells through transcriptional activation of PPARgamma. 2008 Cancer Invest. pmid:18608213
Geraldo IM et al. Rapid antibacterial activity of 2 novel hand soaps: evaluation of the risk of development of bacterial resistance to the antibacterial agents. 2008 Infect Control Hosp Epidemiol pmid:18616390
Muramatsu M et al. Accumulation of prenyl alcohols by terpenoid biosynthesis inhibitors in various microorganisms. 2008 Appl. Microbiol. Biotechnol. pmid:18636253
Lapczynski A et al. Fragrance material review on farnesol. 2008 Food Chem. Toxicol. pmid:18640198
Jahangir T and Sultana S Benzo(a)pyrene-induced genotoxicity: attenuation by farnesol in a mouse model. 2008 J Enzyme Inhib Med Chem pmid:18618320
Schleimer K et al. Competition between native liver and graft in auxiliary liver transplantation in a rat model. 2008 Transplant. Proc. pmid:18555091
Hisajima T et al. Protective effects of farnesol against oral candidiasis in mice. 2008 Microbiol. Immunol. pmid:18667031
Scheper MA et al. Farnesol, a fungal quorum-sensing molecule triggers apoptosis in human oral squamous carcinoma cells. 2008 Neoplasia pmid:18714396
Muramatsu M et al. Various oils and detergents enhance the microbial production of farnesol and related prenyl alcohols. 2008 J. Biosci. Bioeng. pmid:18930003
Qamar W and Sultana S Farnesol ameliorates massive inflammation, oxidative stress and lung injury induced by intratracheal instillation of cigarette smoke extract in rats: an initial step in lung chemoprevention. 2008 Chem. Biol. Interact. pmid:18793622
Peleg AY et al. Prokaryote-eukaryote interactions identified by using Caenorhabditis elegans. 2008 Proc. Natl. Acad. Sci. U.S.A. pmid:18794525
Goldberg L et al. Salirasib (farnesyl thiosalicylic acid) for brain tumor treatment: a convection-enhanced drug delivery study in rats. 2008 Mol. Cancer Ther. pmid:19001442
Cho T et al. [Farnesol as a quorum-sensing molecule in Candida albicans]. 2008 Nihon Ishinkin Gakkai Zasshi pmid:19001754
Davis-Hanna A et al. Farnesol and dodecanol effects on the Candida albicans Ras1-cAMP signalling pathway and the regulation of morphogenesis. 2008 Mol. Microbiol. pmid:18078440
Abbasnezhad H et al. Two different mechanisms for adhesion of Gram-negative bacterium, Pseudomonas fluorescens LP6a, to an oil-water interface. 2008 Colloids Surf B Biointerfaces pmid:17997081
Koo H Strategies to enhance the biological effects of fluoride on dental biofilms. 2008 Adv. Dent. Res. pmid:18694872
Haklai R et al. Orally administered FTS (salirasib) inhibits human pancreatic tumor growth in nude mice. 2008 Cancer Chemother. Pharmacol. pmid:17909812
Zvibel I et al. The effect of Ras inhibition on the proliferation, apoptosis and matrix metalloproteases activity in rat hepatic stellate cells. 2008 Dig. Dis. Sci. pmid:17934818
Journe F et al. Farnesol, a mevalonate pathway intermediate, stimulates MCF-7 breast cancer cell growth through farnesoid-X-receptor-mediated estrogen receptor activation. 2008 Breast Cancer Res. Treat. pmid:17333335
da Silva Morais A et al. Inhibition of the Ras oncoprotein reduces proliferation of hepatocytes in vitro and in vivo in rats. 2008 Clin. Sci. pmid:17678500
Togashi N et al. Effects of two terpene alcohols on the antibacterial activity and the mode of action of farnesol against Staphylococcus aureus. 2008 Molecules pmid:19078849
Shchepin R et al. Influence of heterocyclic and oxime-containing farnesol analogs on quorum sensing and pathogenicity in Candida albicans. 2008 Bioorg. Med. Chem. pmid:18037299
Semighini CP et al. Inhibition of Fusarium graminearum growth and development by farnesol. 2008 FEMS Microbiol. Lett. pmid:18201191
Golczak M et al. Metabolic basis of visual cycle inhibition by retinoid and nonretinoid compounds in the vertebrate retina. 2008 J. Biol. Chem. pmid:18195010
Maher M et al. Activation of TRPA1 by farnesyl thiosalicylic acid. 2008 Mol. Pharmacol. pmid:18171730
Shimomura K et al. Homofarnesals: female sex attractant pheromone components of the southern cowpea weevil, Callosobruchus chinensis. 2008 J. Chem. Ecol. pmid:18351422
Weber K et al. Secretion of E,E-farnesol and biofilm formation in eight different Candida species. 2008 Antimicrob. Agents Chemother. pmid:18332168
Teshima K and Kondo T Analytical method for determination of allylic isoprenols in rat tissues by liquid chromatography/tandem mass spectrometry following chemical derivatization with 3-nitrophtalic anhydride. 2008 J Pharm Biomed Anal pmid:18313250
Blum R et al. Inhibitors of chronically active ras: potential for treatment of human malignancies. 2008 Recent Pat Anticancer Drug Discov pmid:18289122
Tsangarakis C et al. Zeolite NaY-promoted cyclization of farnesal: a short route to nanaimoal. 2008 J. Org. Chem. pmid:18321121
McAlester G et al. Signal-mediated interactions between Pseudomonas aeruginosa and Candida albicans. 2008 J. Med. Microbiol. pmid:18436588
Joo JH and Jetten AM NF-kappaB-dependent transcriptional activation in lung carcinoma cells by farnesol involves p65/RelA(Ser276) phosphorylation via the MEK-MSK1 signaling pathway. 2008 J. Biol. Chem. pmid:18424438
Kebaara BW et al. Candida albicans Tup1 is involved in farnesol-mediated inhibition of filamentous-growth induction. 2008 Eukaryotic Cell pmid:18424510
Rotblat B et al. The Ras inhibitor farnesylthiosalicylic acid (Salirasib) disrupts the spatiotemporal localization of active Ras: a potential treatment for cancer. 2008 Meth. Enzymol. pmid:18374183
Lorek J et al. Influence of farnesol on the morphogenesis of Aspergillus niger. 2008 J. Basic Microbiol. pmid:18383232
Marcuzzi A et al. Natural isoprenoids are able to reduce inflammation in a mouse model of mevalonate kinase deficiency. 2008 Pediatr. Res. pmid:18391837
Chen CK et al. The effect of mutation of F87 on the properties of CYP102A1-CYP4C7 chimeras: altered regiospecificity and substrate selectivity. 2008 J. Biol. Inorg. Chem. pmid:18392864
Woodard B et al. 3D-QSAR of fungal quorum-sensing inhibiting analogs of farnesol. 2007 Mar-Apr J Environ Sci Health B pmid:17454380
Yue W et al. Mechanisms of acquired resistance to endocrine therapy in hormone-dependent breast cancer cells. 2007 Aug-Sep J. Steroid Biochem. Mol. Biol. pmid:17616457
Kuroda M et al. Sesquiterpene farnesol inhibits recycling of the C55 lipid carrier of the murein monomer precursor contributing to increased susceptibility to beta-lactams in methicillin-resistant Staphylococcus aureus. 2007 J. Antimicrob. Chemother. pmid:17242033
Nokhodchi A et al. The effect of terpene concentrations on the skin penetration of diclofenac sodium. 2007 Int J Pharm pmid:17174049
Cho T et al. Transcriptional changes in Candida albicans Genes by both farnesol and high cell density at an early stage of morphogenesis in N-acetyl-D-glucosamine medium. 2007 Nihon Ishinkin Gakkai Zasshi pmid:17975531
Navarathna DH et al. Effect of farnesol on a mouse model of systemic candidiasis, determined by use of a DPP3 knockout mutant of Candida albicans. 2007 Infect. Immun. pmid:17283095
Kuroda M et al. Sesquiterpene farnesol as a competitive inhibitor of lipase activity of Staphylococcus aureus. 2007 FEMS Microbiol. Lett. pmid:17559400
Zundelevich A et al. Suppression of lung cancer tumor growth in a nude mouse model by the Ras inhibitor salirasib (farnesylthiosalicylic acid). 2007 Mol. Cancer Ther. pmid:17541036
Navarathna DH et al. Exogenous farnesol interferes with the normal progression of cytokine expression during candidiasis in a mouse model. 2007 Infect. Immun. pmid:17517874
Uppuluri P et al. Farnesol-mediated inhibition of Candida albicans yeast growth and rescue by a diacylglycerol analogue. 2007 Yeast pmid:17583896
Crowell DN et al. Arabidopsis thaliana plants possess a specific farnesylcysteine lyase that is involved in detoxification and recycling of farnesylcysteine. 2007 Plant J. pmid:17425716
Blum R et al. Gene expression signature of human cancer cell lines treated with the ras inhibitor salirasib (S-farnesylthiosalicylic acid). 2007 Cancer Res. pmid:17409441
Rossignol T et al. Transcriptional response of Candida parapsilosis following exposure to farnesol. 2007 Antimicrob. Agents Chemother. pmid:17684006
Cugini C et al. Farnesol, a common sesquiterpene, inhibits PQS production in Pseudomonas aeruginosa. 2007 Mol. Microbiol. pmid:17640272
Shintre MS et al. Evaluation of an alcohol-based surgical hand disinfectant containing a synergistic combination of farnesol and benzethonium chloride for immediate and persistent activity against resident hand flora of volunteers and with a novel in vitro pig skin model. 2007 Infect Control Hosp Epidemiol pmid:17265401
Zhang L and Hill RP Hypoxia enhances metastatic efficiency in HT1080 fibrosarcoma cells by increasing cell survival in lungs, not cell adhesion and invasion. 2007 Cancer Res. pmid:17699784
Joo JH et al. Farnesol-induced apoptosis in human lung carcinoma cells is coupled to the endoplasmic reticulum stress response. 2007 Cancer Res. pmid:17699800
Lee H et al. Characterization of (E,E)-farnesol and its fatty acid esters from anal scent glands of nutria (Myocastor coypus) by gas chromatography-mass spectrometry and gas chromatography-infrared spectrometry. 2007 J Chromatogr A pmid:17709112
Marciano D et al. Neuroprotective effects of the Ras inhibitor S-trans-trans-farnesylthiosalicylic acid, measured by diffusion-weighted imaging after traumatic brain injury in rats. 2007 J. Neurotrauma pmid:17711399
Cheng AX et al. The rice (E)-beta-caryophyllene synthase (OsTPS3) accounts for the major inducible volatile sesquiterpenes. 2007 Phytochemistry pmid:17524436
Cetin A et al. Angiotensin II-induced MAPK phosphorylation mediated by Ras and/or phospholipase C-dependent phosphorylations but not by protein kinase C phosphorylation in cultured rat vascular smooth muscle cells. 2007 Pharmacology pmid:17135774

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