(e,z)-farnesol

(e,z)-farnesol is a lipid of Prenol Lipids (PR) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 3613 references associated with (e,z)-farnesol in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for (e,z)-farnesol

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (e,z)-farnesol

MeSH term MeSH ID Detail
Adenocarcinoma D000230 166 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Lung Neoplasms D008175 171 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Osteosarcoma D012516 50 associated lipids
Glioma D005910 112 associated lipids
Per page 10 20 50 | Total 23

PubChem Biomolecular Interactions and Pathways

All references with (e,z)-farnesol

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Per page 10 20 50 100 | Total 813
Authors Title Published Journal PubMed Link
Shapira S et al. The tumor suppressor neurofibromin confers sensitivity to apoptosis by Ras-dependent and Ras-independent pathways. 2007 Cell Death Differ. pmid:17096025
Henriques M et al. Effect of farnesol on Candida dubliniensis morphogenesis. 2007 Lett. Appl. Microbiol. pmid:17257261
Marciano D et al. Neuroprotective effects of the Ras inhibitor S-trans-trans-farnesylthiosalicylic acid, measured by diffusion-weighted imaging after traumatic brain injury in rats. 2007 J. Neurotrauma pmid:17711399
Lombardi L et al. Circadian rhythms in Neurospora crassa: clock mutant effects in the absence of a frq-based oscillator. 2007 Genetics pmid:17237512
Wiseman DA et al. Cell cycle arrest by the isoprenoids perillyl alcohol, geraniol, and farnesol is mediated by p21(Cip1) and p27(Kip1) in human pancreatic adenocarcinoma cells. 2007 J. Pharmacol. Exp. Ther. pmid:17138864
Fairn GD et al. A chemogenomic screen in Saccharomyces cerevisiae uncovers a primary role for the mitochondria in farnesol toxicity and its regulation by the Pkc1 pathway. 2007 J. Biol. Chem. pmid:17164236
Hasmim M et al. Zoledronate inhibits endothelial cell adhesion, migration and survival through the suppression of multiple, prenylation-dependent signaling pathways. 2007 J. Thromb. Haemost. pmid:17059425
Beiner ME et al. Ras antagonist inhibits growth and chemosensitizes human epithelial ovarian cancer cells. 2006 Jan-Feb Int. J. Gynecol. Cancer pmid:16515591
Kubista B et al. Anticancer effects of zoledronic acid against human osteosarcoma cells. 2006 J. Orthop. Res. pmid:16602111
Hogan DA Talking to themselves: autoregulation and quorum sensing in fungi. 2006 Eukaryotic Cell pmid:16607008
Chana RS and Brunskill NJ Thiazolidinediones inhibit albumin uptake by proximal tubular cells through a mechanism independent of peroxisome proliferator activated receptor gamma. 2006 Am. J. Nephrol. pmid:16508249
Hemmerlin A et al. Monitoring farnesol-induced toxicity in tobacco BY-2 cells with a fluorescent analog. 2006 Arch. Biochem. Biophys. pmid:16307722
Santen RJ et al. Farnesylthiosalicylic acid: inhibition of proliferation and enhancement of apoptosis of hormone-dependent breast cancer cells. 2006 Anticancer Drugs pmid:16317288
Rüegg T et al. 3-Farnesyl-2-hydroxybenzoic acid is a new anti-Helicobacter pylori compound from Piper multiplinervium. 2006 J Ethnopharmacol pmid:16266794
Amos S et al. Farnesylthiosalicylic acid induces caspase activation and apoptosis in glioblastoma cells. 2006 Cell Death Differ. pmid:16239932
Ong TP et al. Farnesol and geraniol chemopreventive activities during the initial phases of hepatocarcinogenesis involve similar actions on cell proliferation and DNA damage, but distinct actions on apoptosis, plasma cholesterol and HMGCoA reductase. 2006 Carcinogenesis pmid:16332721
Rung E et al. Depletion of substrates for protein prenylation increases apoptosis in human periovulatory granulosa cells. 2006 Mol. Reprod. Dev. pmid:16868926
Saidi S et al. In vitro synergistic effect of farnesol and human gingival cells against Candida albicans. 2006 Yeast pmid:16845684
Jabra-Rizk MA et al. Effect of farnesol on Staphylococcus aureus biofilm formation and antimicrobial susceptibility. 2006 Antimicrob. Agents Chemother. pmid:16569866
Khalil AA et al. Isolation and characterization of a monoamine oxidase B selective inhibitor from tobacco smoke. 2006 Bioorg. Med. Chem. pmid:16458520
Song L A soluble form of phosphatase in Saccharomyces cerevisiae capable of converting farnesyl diphosphate into E,E-farnesol. 2006 Appl. Biochem. Biotechnol. pmid:16484724
Xie J et al. Microparticles developed by electrohydrodynamic atomization for the local delivery of anticancer drug to treat C6 glioma in vitro. 2006 Biomaterials pmid:16490248
Blum R et al. E2F1 identified by promoter and biochemical analysis as a central target of glioblastoma cell-cycle arrest in response to Ras inhibition. 2006 Int. J. Cancer pmid:16496386
Semighini CP et al. Functional characterization of the putative Aspergillus nidulans poly(ADP-ribose) polymerase homolog PrpA. 2006 Genetics pmid:16510786
Jabra-Rizk MA et al. Effect of farnesol on Candida dubliniensis biofilm formation and fluconazole resistance. 2006 FEMS Yeast Res. pmid:17042756
Binda C et al. Structure of the human mitochondrial monoamine oxidase B: new chemical implications for neuroprotectant drug design. 2006 Neurology pmid:17030739
Alem MA et al. Production of tyrosol by Candida albicans biofilms and its role in quorum sensing and biofilm development. 2006 Eukaryotic Cell pmid:16980403
Blum R et al. Suppression of survivin expression in glioblastoma cells by the Ras inhibitor farnesylthiosalicylic acid promotes caspase-dependent apoptosis. 2006 Mol. Cancer Ther. pmid:16985068
Jones G et al. The retinoid-X receptor ortholog, ultraspiracle, binds with nanomolar affinity to an endogenous morphogenetic ligand. 2006 FEBS J. pmid:17064257
Wendland J et al. Use of the Porcine Intestinal Epithelium (PIE)-Assay to analyze early stages of colonization by the human fungal pathogen Candida albicans. 2006 J. Basic Microbiol. pmid:17139615
Hamada M et al. Inhibitory activity of 1-farnesylpyridinium on the spatial control over the assembly of cell wall polysaccharides in Schizosaccharomyces pombe. 2006 J. Biochem. pmid:17092950
Duncan RE and Archer MC Farnesol induces thyroid hormone receptor (THR) beta1 but inhibits THR-mediated signaling in MCF-7 human breast cancer cells. 2006 Biochem. Biophys. Res. Commun. pmid:16540091
Semighini CP et al. Farnesol-induced apoptosis in Aspergillus nidulans reveals a possible mechanism for antagonistic interactions between fungi. 2006 Mol. Microbiol. pmid:16420349
Merino SM and Maren S Hitting Ras where it counts: Ras antagonism in the basolateral amygdala inhibits long-term fear memory. 2006 Eur. J. Neurosci. pmid:16420429
Berzat AC et al. Using inhibitors of prenylation to block localization and transforming activity. 2006 Meth. Enzymol. pmid:16757354
Jahangir T et al. Farnesol prevents Fe-NTA-mediated renal oxidative stress and early tumour promotion markers in rats. 2006 Hum Exp Toxicol pmid:16758765
Erlich S et al. Ras inhibition results in growth arrest and death of androgen-dependent and androgen-independent prostate cancer cells. 2006 Biochem. Pharmacol. pmid:16780807
Fuchs BB and Mylonakis E Using non-mammalian hosts to study fungal virulence and host defense. 2006 Curr. Opin. Microbiol. pmid:16814595
Shintre MS et al. Efficacy of an alcohol-based healthcare hand rub containing synergistic combination of farnesol and benzethonium chloride. 2006 Int J Hyg Environ Health pmid:16750419
Nickerson KW et al. Quorum sensing in dimorphic fungi: farnesol and beyond. 2006 Appl. Environ. Microbiol. pmid:16751484
Jensen EC et al. Farnesol restores wild-type colony morphology to 96% of Candida albicans colony morphology variants recovered following treatment with mutagens. 2006 Genome pmid:16699554
Goodman CL et al. Partial morphological and functional characterization of the corpus allatum-corpus cardiacum complex from the two-spotted stinkbug, Perillus bioculatus (Hemiptera: Pentatomidae). 2005 Mar-Apr In Vitro Cell. Dev. Biol. Anim. pmid:16029075
Funari SS et al. Farnesol and geranylgeraniol modulate the structural properties of phosphatidylethanolamine model membranes. 2005 Jul-Aug Mol. Membr. Biol. pmid:16154902
Kafri M et al. Inhibition of Ras attenuates the course of experimental autoimmune neuritis. 2005 J. Neuroimmunol. pmid:16154640
Taylor MM et al. Enhanced apoptosis through farnesol inhibition of phospholipase D signal transduction. 2005 FEBS J. pmid:16176276
Lakshman R et al. Use of CYP2E1-transfected human liver cell lines in elucidating the actions of ethanol. 2005 Alcohol. Clin. Exp. Res. pmid:16205373
Lagace TA and Ridgway ND Induction of apoptosis by lipophilic activators of CTP:phosphocholine cytidylyltransferase alpha (CCTalpha). 2005 Biochem. J. pmid:16097951
Chen AP et al. Substrate and product specificities of cis-type undecaprenyl pyrophosphate synthase. 2005 Biochem. J. pmid:15447632
Frosch PJ et al. Patch testing with a new fragrance mix detects additional patients sensitive to perfumes and missed by the current fragrance mix. 2005 Contact Derm. pmid:15859993
Frosch PJ et al. Patch testing with a new fragrance mix - reactivity to the individual constituents and chemical detection in relevant cosmetic products. 2005 Contact Derm. pmid:15859994
Koo H et al. Apigenin and tt-farnesol with fluoride effects on S. mutans biofilms and dental caries. 2005 J. Dent. Res. pmid:16246933
Horn TL et al. Modulation of hepatic and renal drug metabolizing enzyme activities in rats by subchronic administration of farnesol. 2005 Chem. Biol. Interact. pmid:15840382
Laffey SF and Butler G Phenotype switching affects biofilm formation by Candida parapsilosis. 2005 Microbiology (Reading, Engl.) pmid:15817776
Yang SP and Raner GM Cytochrome P450 expression and activities in human tongue cells and their modulation by green tea extract. 2005 Toxicol. Appl. Pharmacol. pmid:15629189
Shearer AG and Hampton RY Lipid-mediated, reversible misfolding of a sterol-sensing domain protein. 2005 EMBO J. pmid:15635451
Williams JM and Savage CO Characterization of the regulation and functional consequences of p21ras activation in neutrophils by antineutrophil cytoplasm antibodies. 2005 J. Am. Soc. Nephrol. pmid:15548565
Aronovich R et al. Antiphospholipid antibodies, thrombin and LPS activate brain endothelial cells and Ras-dependent pathways through distinct mechanisms. 2005 Immunobiology pmid:16325498
Westwater C et al. Candida albicans-conditioned medium protects yeast cells from oxidative stress: a possible link between quorum sensing and oxidative stress resistance. 2005 Eukaryotic Cell pmid:16215173
Braun PC The effect of farnesol on amino acid incorporation by a wild-type and cell-wall variant strain of Candida albicans. 2005 Can. J. Microbiol. pmid:16234870
Yu JS et al. Synthesis of farnesol isomers via a modified Wittig procedure. 2005 Org. Lett. pmid:16235893
Navarathna DH et al. Enhanced pathogenicity of Candida albicans pre-treated with subinhibitory concentrations of fluconazole in a mouse model of disseminated candidiasis. 2005 J. Antimicrob. Chemother. pmid:16239285
Ferri N et al. Isothiazole dioxide derivative 6n inhibits vascular smooth muscle cell proliferation and protein farnesylation. 2005 Biochem. Pharmacol. pmid:16257390
McMahon LP et al. Farnesylthiosalicylic acid inhibits mammalian target of rapamycin (mTOR) activity both in cells and in vitro by promoting dissociation of the mTOR-raptor complex. 2005 Mol. Endocrinol. pmid:15459249
Khwaja A et al. The inhibition of human mesangial cell proliferation by S-trans, trans-farnesylthiosalicylic acid. 2005 Kidney Int. pmid:16014024
Mosel DD et al. Farnesol concentrations required to block germ tube formation in Candida albicans in the presence and absence of serum. 2005 Appl. Environ. Microbiol. pmid:16085901
Martin SW et al. Cell cycle dynamics and quorum sensing in Candida albicans chlamydospores are distinct from budding and hyphal growth. 2005 Eukaryotic Cell pmid:16002645
Enjalbert B and Whiteway M Release from quorum-sensing molecules triggers hyphal formation during Candida albicans resumption of growth. 2005 Eukaryotic Cell pmid:16002646
Cao YY et al. cDNA microarray analysis of differential gene expression in Candida albicans biofilm exposed to farnesol. 2005 Antimicrob. Agents Chemother. pmid:15673737
Blum R et al. Ras inhibition in glioblastoma down-regulates hypoxia-inducible factor-1alpha, causing glycolysis shutdown and cell death. 2005 Cancer Res. pmid:15705901
Hubálek F et al. Demonstration of isoleucine 199 as a structural determinant for the selective inhibition of human monoamine oxidase B by specific reversible inhibitors. 2005 J. Biol. Chem. pmid:15710600
Katsuyama M et al. A novel method to control the balance of skin microflora. Part 1. Attack on biofilm of Staphylococcus aureus without antibiotics. 2005 J. Dermatol. Sci. pmid:15927813
Katsuyama M et al. A novel method to control the balance of skin microflora Part 2. A study to assess the effect of a cream containing farnesol and xylitol on atopic dry skin. 2005 J. Dermatol. Sci. pmid:15927814
Shchepin R et al. Biologically active fluorescent farnesol analogs. 2005 Chem. Biol. pmid:15975508
Kang L et al. SMGA gels for the skin permeation of haloperidol. 2005 J Control Release pmid:15975680
Yue W et al. Farnesylthiosalicylic acid blocks mammalian target of rapamycin signaling in breast cancer cells. 2005 Int. J. Cancer pmid:15957161
Bachireddy P et al. Getting at MYC through RAS. 2005 Clin. Cancer Res. pmid:15958607
Yaari S et al. Disruption of cooperation between Ras and MycN in human neuroblastoma cells promotes growth arrest. 2005 Clin. Cancer Res. pmid:15958613
Rowat AC et al. Effects of farnesol on the physical properties of DMPC membranes. 2005 Biochim. Biophys. Acta pmid:15963943
Jahangir T et al. Alleviation of free radical mediated oxidative and genotoxic effects of cadmium by farnesol in Swiss albino mice. 2005 Redox Rep. pmid:16438802
Ruiz-Velasco N et al. Statins upregulate CD36 expression in human monocytes, an effect strengthened when combined with PPAR-gamma ligands Putative contribution of Rho GTPases in statin-induced CD36 expression. 2004 Biochem. Pharmacol. pmid:14698043
Yang Z et al. Host plant volatiles synergize response to sex pheromone in codling moth, Cydia pomonella. 2004 J. Chem. Ecol. pmid:15139312
Inoue Y et al. The antibacterial effects of terpene alcohols on Staphylococcus aureus and their mode of action. 2004 FEMS Microbiol. Lett. pmid:15321680
Rowat AC and Davis JH Farnesol-DMPC phase behaviour: a (2)H-NMR study. 2004 Biochim. Biophys. Acta pmid:15003880
Hogan DA et al. A Pseudomonas aeruginosa quorum-sensing molecule influences Candida albicans morphology. 2004 Mol. Microbiol. pmid:15554963
Luxová A et al. Absolute configuration of chiral terpenes in marking pheromones of bumblebees and cuckoo bumblebees. 2004 Chirality pmid:15034905
Murataliev MB et al. Chimeragenesis of the fatty acid binding site of cytochrome P450BM3. Replacement of residues 73-84 with the homologous residues from the insect cytochrome P450 CYP4C7. 2004 Biochemistry pmid:14967018
McPherson RA et al. The novel Ras antagonist, farnesylthiosalicylate, suppresses growth of prostate cancer in vitro. 2004 Prostate pmid:14968433
Hornby JM et al. Inoculum size effect in dimorphic fungi: extracellular control of yeast-mycelium dimorphism in Ceratocystis ulmi. 2004 Appl. Environ. Microbiol. pmid:15006753
Wozniak M et al. Alternative farnesoid structures induce different conformational outcomes upon the Drosophila ortholog of the retinoid X receptor, ultraspiracle. 2004 Insect Biochem. Mol. Biol. pmid:15522611
Rudi A et al. Likonides A and B: new ansa farnesyl quinols from the marine sponge Hyatella sp. 2004 Org. Lett. pmid:15496087
Shalom-Feuerstein R et al. Restoration of sensitivity to anoikis in Ras-transformed rat intestinal epithelial cells by a Ras inhibitor. 2004 Cell Death Differ. pmid:14576773
Reif S et al. Treatment of thioacetamide-induced liver cirrhosis by the Ras antagonist, farnesylthiosalicylic acid. 2004 J. Hepatol. pmid:15288472
Fukuda S and Pelus LM Activated H-Ras regulates hematopoietic cell survival by modulating Survivin. 2004 Biochem. Biophys. Res. Commun. pmid:15369798
Dumitru R et al. Defined anaerobic growth medium for studying Candida albicans basic biology and resistance to eight antifungal drugs. 2004 Antimicrob. Agents Chemother. pmid:15215080
Schnuch A et al. Contact allergy to farnesol in 2021 consecutively patch tested patients. Results of the IVDK. 2004 Contact Derm. pmid:15153123
Hornby JM and Nickerson KW Enhanced production of farnesol by Candida albicans treated with four azoles. 2004 Antimicrob. Agents Chemother. pmid:15155241
DeBarber AE et al. Omega-hydroxylation of farnesol by mammalian cytochromes p450. 2004 Biochim. Biophys. Acta pmid:15158752
Sato T et al. Farnesol, a morphogenetic autoregulatory substance in the dimorphic fungus Candida albicans, inhibits hyphae growth through suppression of a mitogen-activated protein kinase cascade. 2004 Biol. Pharm. Bull. pmid:15133261
Thorpe JL et al. Germ cell migration in zebrafish is dependent on HMGCoA reductase activity and prenylation. 2004 Dev. Cell pmid:14960282
George J et al. Inhibition of intimal thickening in the rat carotid artery injury model by a nontoxic Ras inhibitor. 2004 Arterioscler. Thromb. Vasc. Biol. pmid:14670932

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