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Farnesol-DMPC phase behaviour: a (2)H-NMR study. |
2004 |
Biochim. Biophys. Acta |
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Restoration of sensitivity to anoikis in Ras-transformed rat intestinal epithelial cells by a Ras inhibitor. |
2004 |
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Germ cell migration in zebrafish is dependent on HMGCoA reductase activity and prenylation. |
2004 |
Dev. Cell |
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Inhibition of intimal thickening in the rat carotid artery injury model by a nontoxic Ras inhibitor. |
2004 |
Arterioscler. Thromb. Vasc. Biol. |
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Farnesol for aerosol inhalation: nebulization and activity against human lung cancer cells. |
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J Pharm Pharm Sci |
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2003 |
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Chemical ecology of oribatid mites III. Chemical composition of oil gland exudates from two oribatid mites, Trhypochthoniellus sp. and Trhypochthonius japonicus (Acari: Trhypochthoniidae). |
2003 |
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Circadian rhythms in Neurospora crassa: farnesol or geraniol allow expression of rhythmicity in the otherwise arrhythmic strains frq10, wc-1, and wc-2. |
2003 |
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Inhibition of Streptococcus mutans biofilm accumulation and polysaccharide production by apigenin and tt-farnesol. |
2003 |
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Identification of pheromones and optimization of bait composition for click beetle pests (Coleoptera: Elateridae) in Central and Western Europe. |
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Inhibition of ras by farnesylthiosalicylate significantly reduces the levels of autoantibodies in two animal models of the antiphospholipid syndrome. |
2003 |
Immunobiology |
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New approaches to the understanding of tamoxifen action and resistance. |
2003 |
Endocr. Relat. Cancer |
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The Ras inhibitor S-trans, trans-farnesylthiosalicylic acid exerts long-lasting neuroprotection in a mouse closed head injury model. |
2003 |
J. Cereb. Blood Flow Metab. |
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Farnesol biosynthesis in Candida albicans: cellular response to sterol inhibition by zaragozic acid B. |
2003 |
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The inhibition of degradation of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase by sterol regulatory element binding protein cleavage-activating protein requires four phenylalanine residues in span 6 of HMG-CoA reductase transmembrane domain. |
2003 |
Arch. Biochem. Biophys. |
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Studies on G-protein alpha.betagamma heterotrimer formation reveal a putative S-prenyl-binding site in the alpha subunit. |
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Quorum sensing in Candida albicans: probing farnesol's mode of action with 40 natural and synthetic farnesol analogs. |
2003 |
Chem. Biol. |
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Role of cholesterol-enriched diet and the mevalonate pathway in cardiac nitric oxide synthesis. |
2003 |
Basic Res. Cardiol. |
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Nitrogen-containing bisphosphonates induce S-phase cell cycle arrest and apoptosis of myeloma cells by activating MAPK pathway and inhibiting mevalonate pathway. |
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Ras antagonist farnesylthiosalicylic acid (FTS) reduces glomerular cellular proliferation and macrophage number in rat thy-1 nephritis. |
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J. Am. Soc. Nephrol. |
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2003 |
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Farnesyl transferase inhibitor SCH66336 is cytostatic, pro-apoptotic and enhances chemosensitivity to cisplatin in melanoma cells. |
2003 |
Int. J. Cancer |
pmid:12673674
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Detection of farnesyl diphosphate accumulation in yeast ERG9 mutants. |
2003 |
Anal. Biochem. |
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Farnesyl thiosalicylic acid chemosensitizes human melanoma in vivo. |
2003 |
J. Invest. Dermatol. |
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The adenosine inhibition of glutamate exocytosis in synaptosomes is removed by the collapse of the vesicle-cytosol deltapH plus the opening of farnesol-sensitive Ca(2+) channels. |
2003 |
Cell Calcium |
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Effects of risedronate, alendronate, and etidronate on the viability and activity of rat bone marrow stromal cells in vitro. |
2003 |
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Squalene synthase inhibitors suppress triglyceride biosynthesis through the farnesol pathway in rat hepatocytes. |
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Eur J Pharm Sci |
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2003 |
Cell. Mol. Life Sci. |
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Sensitization of Staphylococcus aureus and Escherichia coli to antibiotics by the sesquiterpenoids nerolidol, farnesol, bisabolol, and apritone. |
2003 |
Antimicrob. Agents Chemother. |
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Protein farnesyltransferase inhibitors interfere with farnesyl diphosphate binding by rubber transferase. |
2003 |
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Farnesyl-O-acetylhydroquinone and geranyl-O-acetylhydroquinone suppress the proliferation of murine B16 melanoma cells, human prostate and colon adenocarcinoma cells, human lung carcinoma cells, and human leukemia cells. |
2003 |
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Increase in peripheral benzodiazepine receptors and loss of glutamate NMDA receptors in a mouse model of closed head injury: a quantitative autoradiographic study. |
2003 |
Neuroimage |
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2002 |
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The maize gene terpene synthase 1 encodes a sesquiterpene synthase catalyzing the formation of (E)-beta-farnesene, (E)-nerolidol, and (E,E)-farnesol after herbivore damage. |
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Plant Physiol. |
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Farnesylpyridinium, an analog of isoprenoid farnesol, induces apoptosis but suppresses apoptotic body formation in human promyelocytic leukemia cells. |
2002 |
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The Ras inhibitor S-trans,trans-farnesylthiosalicylic acid chemosensitizes human tumor cells without causing resistance. |
2002 |
Clin. Cancer Res. |
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Farnesyl thiosalicylic acid inhibits the growth of melanoma cells through a combination of cytostatic and pro-apoptotic effects. |
2002 |
Int. J. Cancer |
pmid:11920610
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Effects of allatotropin and allatostatin on in vitro production of juvenile hormones by the corpora allata of virgin females of the moths of Heliothis virescens and Manduca sexta. |
2002 |
Peptides |
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Effect of novel modulators of protein kinase C activity upon chemotherapy-induced differentiation and apoptosis in myeloid leukemic cells. |
2002 |
Anticancer Drugs |
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2002 |
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2002 |
Chemotherapy |
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Dual action of isoprenols from herbal medicines on both PPARgamma and PPARalpha in 3T3-L1 adipocytes and HepG2 hepatocytes. |
2002 |
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Functional inhibition of Ras by S-trans,trans-farnesyl thiosalicylic acid attenuates atherosclerosis in apolipoprotein E knockout mice. |
2002 |
Circulation |
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Farnesol as an inhibitor and substrate for rabbit liver microsomal P450 enzymes. |
2002 |
Biochem. Biophys. Res. Commun. |
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Lack of isoprenoid products raises ex vivo interleukin-1beta secretion in hyperimmunoglobulinemia D and periodic fever syndrome. |
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Solution- and solid-phase synthesis of the polybasic lipid-modified C termini of Rho A and K-Ras 4B. |
2002 |
Chembiochem |
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Inhibition of Candida albicans biofilm formation by farnesol, a quorum-sensing molecule. |
2002 |
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Treatment of the chronic inflammation in peripheral target tissue improves the crushed nerve recovery in the rat: histopathological assessment of the nerve recovery. |
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Evidence for Ras-dependent signal transduction in phenytoin teratogenicity. |
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2001 |
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Farnesol oxidation in insects: evidence that the biosynthesis of insect juvenile hormone is mediated by a specific alcohol oxidase. |
2001 |
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(+)-epi-Alpha-bisabolol [correction of bisbolol] is the wound-healing principle of Peperomia galioides: investigation of the in vivo wound-healing activity of related terpenoids. |
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Requirement of c-jun N-terminal kinase for apoptotic cell death induced by farnesyltransferase inhibitor, farnesylamine, in human pancreatic cancer cells. |
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Partial characterization of farnesyl and geranylgeranyl diphosphatases induced in rice seedlings by UV-C irradiation. |
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Plant Cell Physiol. |
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Treatment of MRL/lpr mice, a genetic autoimmune model, with the Ras inhibitor, farnesylthiosalicylate (FTS). |
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Stereochemical analysis of the reaction catalyzed by human protein geranylgeranyl transferase. |
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Biochemistry |
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Role of the ERK pathway in the activation of store-mediated calcium entry in human platelets. |
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Glutaredoxin protects cerebellar granule neurons from dopamine-induced apoptosis by dual activation of the ras-phosphoinositide 3-kinase and jun n-terminal kinase pathways. |
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Quorum sensing in the dimorphic fungus Candida albicans is mediated by farnesol. |
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Block of voltage-dependent calcium channels by aliphatic monoamines. |
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Farnesyl anthranilate suppresses the growth, in vitro and in vivo, of murine B16 melanomas. |
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Transannular Diels-Alder studies on the asymmetric total synthesis of chatancin: the pyranophane approach. |
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Farnesol stimulates differentiation in epidermal keratinocytes via PPARalpha. |
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Farnesol modulates membrane currents in human retinal glial cells. |
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A novel Ras antagonist regulates both oncogenic Ras and the tumor suppressor p53 in colon cancer cells. |
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Farnesyl transferase inhibitors: current developments and future perspectives. |
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RAS inhibitors: potential for cancer therapeutics. |
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Mol Med Today |
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Farnesol-induced cell death and stimulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity in tobacco cv bright yellow-2 cells. |
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Fluvastatin inhibits basal and stimulated plasminogen activator inhibitor 1, but induces tissue type plasminogen activator in cultured human endothelial cells. |
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Preferential induction of apoptosis of leukaemic cells by farnesol. |
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Contact Derm. |
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Farnesylcysteine analogues inhibit store-regulated Ca2+ entry in human platelets: evidence for involvement of small GTP-binding proteins and actin cytoskeleton. |
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The mevalonate/isoprenoid pathway inhibitor apomine (SR-45023A) is antiproliferative and induces apoptosis similar to farnesol. |
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Farnesol-induced generation of reactive oxygen species dependent on mitochondrial transmembrane potential hyperpolarization mediated by F(0)F(1)-ATPase in yeast. |
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FEBS Lett. |
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Inhibition of human B cell activation by a novel nonsteroidal anti-inflammatory drug, indometacin famesil. |
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Immunopharmacology |
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Activation of the cholesterol pathway and Ras maturation in response to stress. |
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Oncogene |
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Farnesol is utilized for isoprenoid biosynthesis in plant cells via farnesyl pyrophosphate formed by successive monophosphorylation reactions. |
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Novel Ras antagonist blocks human melanoma growth. |
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Proc. Natl. Acad. Sci. U.S.A. |
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1999 |
Biochim. Biophys. Acta |
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The Ras antagonist, farnesylthiosalicylic acid (FTS), inhibits experimentally-induced liver cirrhosis in rats. |
1999 |
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