| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Hartwig S et al. | Expression, purification and activity assay of a patchoulol synthase cDNA variant fused to thioredoxin in Escherichia coli. | 2014 | Protein Expr. Purif. | pmid:24576659 |
| Gonzalez V et al. | Evolutionary and mechanistic insights from the reconstruction of α-humulene synthases from a modern (+)-germacrene A synthase. | 2014 | J. Am. Chem. Soc. | pmid:25230152 |
| Eljounaidi K et al. | Cytochrome P450s from Cynara cardunculus L. CYP71AV9 and CYP71BL5, catalyze distinct hydroxylations in the sesquiterpene lactone biosynthetic pathway. | 2014 | Plant Sci. | pmid:24767116 |
| Cascón O et al. | Chemoenzymatic preparation of germacrene analogues. | 2012 | Chem. Commun. (Camb.) | pmid:22914774 |
| Cankar K et al. | A chicory cytochrome P450 mono-oxygenase CYP71AV8 for the oxidation of (+)-valencene. | 2011 | FEBS Lett. | pmid:21115006 |
| Ikezawa N et al. | Lettuce costunolide synthase (CYP71BL2) and its homolog (CYP71BL1) from sunflower catalyze distinct regio- and stereoselective hydroxylations in sesquiterpene lactone metabolism. | 2011 | J. Biol. Chem. | pmid:21515683 |
| Faraldos JA and Allemann RK | Inhibition of (+)-aristolochene synthase with iminium salts resembling eudesmane cation. | 2011 | Org. Lett. | pmid:21271717 |
| Liu Q et al. | Reconstitution of the costunolide biosynthetic pathway in yeast and Nicotiana benthamiana. | 2011 | PLoS ONE | pmid:21858047 |
| Faraldos JA et al. | Probing eudesmane cation-Ï€ interactions in catalysis by aristolochene synthase with non-canonical amino acids. | 2011 | J. Am. Chem. Soc. | pmid:21815676 |
| Nguyen DT et al. | Biochemical conservation and evolution of germacrene A oxidase in asteraceae. | 2010 | J. Biol. Chem. | pmid:20351109 |
| Faraldos JA et al. | Intermediacy of eudesmane cation during catalysis by aristolochene synthase. | 2010 | J. Org. Chem. | pmid:20095558 |
| Miller DJ et al. | 6- and 14-Fluoro farnesyl diphosphate: mechanistic probes for the reaction catalysed by aristolochene synthase. | 2009 | Org. Biomol. Chem. | pmid:19225680 |
| Nelson LJ et al. | Cuticular hydrocarbons and soldier defense secretions of Reticulitermes in southern California: a critical analysis of the taxonomy of the genus in North America. | 2008 | J. Chem. Ecol. | pmid:18941841 |
| Faraldos JA et al. | Interception of the enzymatic conversion of farnesyl diphosphate to 5-epi-aristolochene by using a fluoro substrate analogue: 1-fluorogermacrene A from (2E,6Z)-6-fluorofarnesyl diphosphate. | 2007 | Chembiochem | pmid:17886322 |
| Miller DJ et al. | Aristolochene synthase-catalyzed cyclization of 2-fluorofarnesyl-diphosphate to 2-fluorogermacrene A. | 2007 | Chembiochem | pmid:17683054 |
| Chang YJ et al. | Point mutation of (+)-germacrene A synthase from Ixeris dentata. | 2005 | Biotechnol. Lett. | pmid:15834787 |
| Felicetti B and Cane DE | Aristolochene synthase: mechanistic analysis of active site residues by site-directed mutagenesis. | 2004 | J. Am. Chem. Soc. | pmid:15186158 |
| Forcat S and Allemann RK | Dual role for phenylalanine 178 during catalysis by aristolochene synthase. | 2004 | Chem. Commun. (Camb.) | pmid:15367991 |
| Lou Y and Baldwin IT | Nitrogen supply influences herbivore-induced direct and indirect defenses and transcriptional responses in Nicotiana attenuata. | 2004 | Plant Physiol. | pmid:15133153 |
| Aharoni A et al. | Terpenoid metabolism in wild-type and transgenic Arabidopsis plants. | 2003 | Plant Cell | pmid:14630967 |
| Greenhagen BT et al. | Probing sesquiterpene hydroxylase activities in a coupled assay with terpene synthases. | 2003 | Arch. Biochem. Biophys. | pmid:12504906 |
| Yang D et al. | [Chemical constituents of the essential oil from the fruits of Lindera glauca and its antifungal activities]. | 1999 | Zhong Yao Cai | pmid:12575067 |
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(+) Germacrene A
(+) germacrene a is a lipid of Prenol Lipids (PR) class.
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