Alpha-humulene

Alpha-humulene is a lipid of Prenol Lipids (PR) class.

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 434 references associated with Alpha-humulene in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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PREMA BR and BHATTACHRYYA PK Microbiological transformations of terpenes. III. Transformations of some mono- and sesqui-terpenes. 1962 Appl Microbiol pmid:13986020
Keerthi D et al. Metabolic profiling of Zingiber zerumbet following Pythium myriotylum infection: investigations on the defensive role of the principal secondary metabolite, zerumbone. 2014 Appl. Biochem. Biotechnol. pmid:24414941
Harada H et al. Efficient synthesis of functional isoprenoids from acetoacetate through metabolic pathway-engineered Escherichia coli. 2009 Appl. Microbiol. Biotechnol. pmid:18836713
Dehal SS and Croteau R Partial purification and characterization of two sesquiterpene cyclases from sage (Salvia officinalis) which catalyze the respective conversion of farnesyl pyrophosphate to humulene and caryophyllene. 1988 Arch. Biochem. Biophys. pmid:3355155
Croteau R and Gundy A Cyclization of farnesyl pyrophosphate to the sesquiterpene olefins humulene and caryophyllene by an enzyme system from sage (Salvia officinalis). 1984 Arch. Biochem. Biophys. pmid:6486812
Li JX et al. Rational engineering of plasticity residues of sesquiterpene synthases from Artemisia annua: product specificity and catalytic efficiency. 2013 Biochem. J. pmid:23438177
Satsu H et al. Regulation of interleukin-8 secretion in human intestinal epithelial Caco-2 cells by alpha-humulene. 2004 Biofactors pmid:15630185
Ogawa K et al. Locomotor-reducing effects and structural characteristics of inhaled zerumbone and tetrahydrozerumbone derivatives. 2014 Biol. Pharm. Bull. pmid:25177038
Murakami A et al. Identification of zerumbone in Zingiber zerumbet Smith as a potent inhibitor of 12-O-tetradecanoylphorbol-13-acetate-induced Epstein-Barr virus activation. 1999 Biosci. Biotechnol. Biochem. pmid:10586508
Eguchi A et al. Zerumbone suppresses phorbol ester-induced expression of multiple scavenger receptor genes in THP-1 human monocytic cells. 2007 Biosci. Biotechnol. Biochem. pmid:17420607
Calleja MA et al. The antioxidant effect of β-caryophyllene protects rat liver from carbon tetrachloride-induced fibrosis by inhibiting hepatic stellate cell activation. 2013 Br. J. Nutr. pmid:22717234
Rogerio AP et al. Preventive and therapeutic anti-inflammatory properties of the sesquiterpene alpha-humulene in experimental airways allergic inflammation. 2009 Br. J. Pharmacol. pmid:19438512
Yu F et al. Zingiber zerumbet CYP71BA1 catalyzes the conversion of α-humulene to 8-hydroxy-α-humulene in zerumbone biosynthesis. 2011 Cell. Mol. Life Sci. pmid:20730551
Chen SP et al. Novel norhumulene and xeniaphyllane-derived terpenoids from a formosan soft coral Sinularia gibberosa. 2009 Chem. Pharm. Bull. pmid:19182406
Abraham WR Bioactive sesquiterpenes produced by fungi: are they useful for humans as well? 2001 Curr. Med. Chem. pmid:11281843
Fernandes ES et al. Anti-inflammatory effects of compounds alpha-humulene and (-)-trans-caryophyllene isolated from the essential oil of Cordia verbenacea. 2007 Eur. J. Pharmacol. pmid:17559833
Laznik Z and Trdan S An investigation on the chemotactic responses of different entomopathogenic nematode strains to mechanically damaged maize root volatile compounds. 2013 Exp. Parasitol. pmid:23562713