Vomitoxin

Vomitoxin is a lipid of Prenol Lipids (PR) class. Vomitoxin is associated with abnormalities such as Infection and Gastroenteritis. The involved functions are known as mRNA Expression, Inflammation, Transcription, Genetic, Protein Biosynthesis and Adverse effects. Vomitoxin often locates in Lymphoid Tissue, Immune system, Bone Marrow and Plasma membrane. The associated genes with Vomitoxin are IMPACT gene, HIST1H1C gene and RBM39 gene. The related experimental models are Mouse Model.

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Introduction

To understand associated biological information of Vomitoxin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Vomitoxin?

Vomitoxin is suspected in Infection, Gastroenteritis and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Vomitoxin

PubChem Associated disorders and diseases

What pathways are associated with Vomitoxin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Vomitoxin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Vomitoxin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Vomitoxin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Vomitoxin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Vomitoxin?

Mouse Model

Mouse Model are used in the study 'Dietary fish oil suppresses experimental immunoglobulin a nephropathy in mice.' (Pestka JJ et al., 2002).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Vomitoxin

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Authors Title Published Journal PubMed Link
Brera C et al. Exposure assessment for Italian population groups to deoxynivalenol deriving from pasta consumption. 2013 Toxins (Basel) pmid:24287568
Basso K et al. Deoxynivanelol and fumonisin, alone or in combination, induce changes on intestinal junction complexes and in E-cadherin expression. 2013 Toxins (Basel) pmid:24287571
Wilson NM et al. Modification of the Mycotoxin Deoxynivalenol Using Microorganisms Isolated from Environmental Samples. 2017 Toxins (Basel) pmid:28420137
Drakulic J et al. Contrasting Roles of Deoxynivalenol and Nivalenol in Host-Mediated Interactions between Fusarium graminearum and Sitobion avenae. 2016 Toxins (Basel) pmid:27916862
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Cirlini M et al. Durum wheat (Triticum Durum Desf.) lines show different abilities to form masked mycotoxins under greenhouse conditions. 2014 Toxins (Basel) pmid:24368326
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Simsek S et al. Occurrence of deoxynivalenol and deoxynivalenol-3-glucoside in hard red spring wheat grown in the USA. 2013 Toxins (Basel) pmid:24351720
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Giménez I et al. Effects of bread making and wheat germ addition on the natural deoxynivalenol content in bread. 2014 Toxins (Basel) pmid:24451845
Wiwart M et al. The Response of Selected Triticum spp. Genotypes with Different Ploidy Levels to Head Blight Caused by Fusarium culmorum (W.G.Smith) Sacc. 2016 Toxins (Basel) pmid:27092526
Sanders M et al. Comparison of Enzyme-Linked Immunosorbent Assay, Surface Plasmon Resonance and Biolayer Interferometry for Screening of Deoxynivalenol in Wheat and Wheat Dust. 2016 Toxins (Basel) pmid:27077883
Goossens J et al. Influence of mycotoxins and a mycotoxin adsorbing agent on the oral bioavailability of commonly used antibiotics in pigs. 2012 Toxins (Basel) pmid:22606377
Schmeitzl C et al. The Metabolic Fate of Deoxynivalenol and Its Acetylated Derivatives in a Wheat Suspension Culture: Identification and Detection of DON-15-O-Glucoside, 15-Acetyl-DON-3-O-Glucoside and 15-Acetyl-DON-3-Sulfate. 2015 Toxins (Basel) pmid:26274975
Clark ES et al. Murine Anorectic Response to Deoxynivalenol (Vomitoxin) Is Sex-Dependent. 2015 Toxins (Basel) pmid:26230710
Generotti S et al. Deoxynivalenol & Deoxynivalenol-3-Glucoside Mitigation through Bakery Production Strategies: Effective Experimental Design within Industrial Rusk-Making Technology. 2015 Toxins (Basel) pmid:26213969
Michlmayr H et al. Biochemical Characterization of a Recombinant UDP-glucosyltransferase from Rice and Enzymatic Production of Deoxynivalenol-3-O-β-D-glucoside. 2015 Toxins (Basel) pmid:26197338
Alizadeh A et al. Deoxynivalenol Impairs Weight Gain and Affects Markers of Gut Health after Low-Dose, Short-Term Exposure of Growing Pigs. 2015 Toxins (Basel) pmid:26067367
Manda G et al. Dual effects exerted in vitro by micromolar concentrations of deoxynivalenol on undifferentiated caco-2 cells. 2015 Toxins (Basel) pmid:25690693
Antonissen G et al. Chronic exposure to deoxynivalenol has no influence on the oral bioavailability of fumonisin B1 in broiler chickens. 2015 Toxins (Basel) pmid:25690690
Zhou HR et al. Direct activation of ribosome-associated double-stranded RNA-dependent protein kinase (PKR) by deoxynivalenol, anisomycin and ricin: a new model for ribotoxic stress response induction. 2014 Toxins (Basel) pmid:25521494
Pietsch C et al. Occurrence of deoxynivalenol and zearalenone in commercial fish feed: an initial study. 2013 Toxins (Basel) pmid:23325300
Mesterházy A et al. Role of fungicides, application of nozzle types, and the resistance level of wheat varieties in the control of Fusarium head blight and deoxynivalenol. 2011 Toxins (Basel) pmid:22174980
Gajęcka M et al. The expression of type-1 and type-2 nitric oxide synthase in selected tissues of the gastrointestinal tract during mixed mycotoxicosis. 2013 Toxins (Basel) pmid:24284830
Awad W et al. The toxicological impacts of the Fusarium mycotoxin, deoxynivalenol, in poultry flocks with special reference to immunotoxicity. 2013 Toxins (Basel) pmid:23628787
Weaver AC et al. Protective effect of two yeast based feed additives on pigs chronically exposed to deoxynivalenol and zearalenone. 2014 Toxins (Basel) pmid:25533517
Kim DH et al. Incidence and levels of deoxynivalenol, fumonisins and zearalenone contaminants in animal feeds used in Korea in 2012. 2014 Toxins (Basel) pmid:24366207
Waśkiewicz A et al. Deoxynivalenol and oxidative stress indicators in winter wheat inoculated with Fusarium graminearum. 2014 Toxins (Basel) pmid:24514944
Ivanova L et al. Cytotoxicity of enniatins A, A1, B, B1, B2 and B3 from Fusarium avenaceum. 2006 Toxicon pmid:16730043
Abbas HK et al. Cytotoxicity and phytotoxicity of trichothecene mycotoxins produced by Fusarium spp. 2013 Toxicon pmid:23933195
Luongo D et al. Effects of four Fusarium toxins (fumonisin B(1), alpha-zearalenol, nivalenol and deoxynivalenol) on porcine whole-blood cellular proliferation. 2008 Toxicon pmid:18620720
Ruiz MJ et al. Toxicological interactions between the mycotoxins beauvericin, deoxynivalenol and T-2 toxin in CHO-K1 cells in vitro. 2011 Toxicon pmid:21821061
Ficheux AS et al. Co-exposure of Fusarium mycotoxins: in vitro myelotoxicity assessment on human hematopoietic progenitors. 2012 Toxicon pmid:22921581
Gajęcka M et al. Changes in the metabolic profile and body weight of pre-pubertal gilts during prolonged monotonic exposure to low doses of zearalenone and deoxynivalenol. 2017 Toxicon pmid:27840141
Ji J et al. GC-TOF/MS-based metabolomic strategy for combined toxicity effects of deoxynivalenol and zearalenone on murine macrophage ANA-1 cells. 2016 Toxicon pmid:27530666
Albonico M et al. Toxicological effects of fumonisin B1 alone and in combination with other fusariotoxins on bovine granulosa cells. 2016 Toxicon pmid:27108238
Pizzo F et al. In vitro effects of deoxynivalenol and zearalenone major metabolites alone and combined, on cell proliferation, steroid production and gene expression in bovine small-follicle granulosa cells. 2016 Toxicon pmid:26657070
Ueno Y et al. Examination of Chinese and U.S.S.R. cereals for the Fusarium mycotoxins, nivalenol, deoxynivalenol and zearalenone. 1986 Toxicon pmid:2944249
Dinu D et al. Adapted response of the antioxidant defense system to oxidative stress induced by deoxynivalenol in Hek-293 cells. 2011 Toxicon pmid:21549142
Lucioli J et al. The food contaminant deoxynivalenol activates the mitogen activated protein kinases in the intestine: interest of ex vivo models as an alternative to in vivo experiments. 2013 Toxicon pmid:23403092
Caloni F et al. Effects of a trichothecene, T-2 toxin, on proliferation and steroid production by porcine granulosa cells. 2009 Toxicon pmid:19463844
Sun LH et al. Individual and combined cytotoxic effects of aflatoxin B1, zearalenone, deoxynivalenol and fumonisin B1 on BRL 3A rat liver cells. 2015 Toxicon pmid:25549941
Zhang X et al. The role of oxidative stress in deoxynivalenol-induced DNA damage in HepG2 cells. 2009 Toxicon pmid:19486909
Luongo D et al. Trichothecenes NIV and DON modulate the maturation of murine dendritic cells. 2010 Toxicon pmid:19635492
Kouadio JH et al. Effects of combinations of Fusarium mycotoxins on the inhibition of macromolecular synthesis, malondialdehyde levels, DNA methylation and fragmentation, and viability in Caco-2 cells. 2007 Toxicon pmid:17109910
Zielonka Ł et al. The effect of environmental mycotoxins on selected ovarian tissue fragments of multiparous female wild boars at the beginning of astronomical winter. 2014 Toxicon pmid:25016169
Bensassi F et al. In vitro investigation of toxicological interactions between the fusariotoxins deoxynivalenol and zearalenone. 2014 Toxicon pmid:24680766
Yang H et al. Ribotoxic mycotoxin deoxynivalenol induces G2/M cell cycle arrest via p21Cip/WAF1 mRNA stabilization in human epithelial cells. 2008 Toxicology pmid:18006205
Kouadio JH et al. Comparative study of cytotoxicity and oxidative stress induced by deoxynivalenol, zearalenone or fumonisin B1 in human intestinal cell line Caco-2. 2005 Toxicology pmid:16019124
Waché YJ et al. The mycotoxin deoxynivalenol inhibits the cell surface expression of activation markers in human macrophages. 2009 Toxicology pmid:19549553