Vomitoxin

Vomitoxin is a lipid of Prenol Lipids (PR) class. Vomitoxin is associated with abnormalities such as Infection and Gastroenteritis. The involved functions are known as mRNA Expression, Inflammation, Transcription, Genetic, Protein Biosynthesis and Adverse effects. Vomitoxin often locates in Lymphoid Tissue, Immune system, Bone Marrow and Plasma membrane. The associated genes with Vomitoxin are IMPACT gene, HIST1H1C gene and RBM39 gene. The related experimental models are Mouse Model.

Cross Reference

Introduction

To understand associated biological information of Vomitoxin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Vomitoxin?

Vomitoxin is suspected in Infection, Gastroenteritis and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Vomitoxin

MeSH term MeSH ID Detail
Ascaridiasis D001198 1 associated lipids
Kashin-Beck Disease D057767 2 associated lipids
Coronavirus Infections D018352 4 associated lipids
Adrenocortical Carcinoma D018268 4 associated lipids
Splenic Diseases D013158 5 associated lipids
Mycotoxicosis D015651 5 associated lipids
Bronchopneumonia D001996 7 associated lipids
Glomerulonephritis, IGA D005922 7 associated lipids
Anorexia D000855 8 associated lipids
Immune Complex Diseases D007105 9 associated lipids
Fetal Weight D020567 12 associated lipids
Hematuria D006417 13 associated lipids
Fetal Resorption D005327 15 associated lipids
Thymus Neoplasms D013953 15 associated lipids
Swine Diseases D013553 16 associated lipids
Mycoses D009181 18 associated lipids
Esophageal Neoplasms D004938 20 associated lipids
Poultry Diseases D011201 21 associated lipids
Stomach Neoplasms D013274 24 associated lipids
Obesity D009765 29 associated lipids
Per page 10 20 50 | Total 29

PubChem Associated disorders and diseases

What pathways are associated with Vomitoxin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Vomitoxin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Vomitoxin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Vomitoxin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Vomitoxin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Vomitoxin?

Mouse Model

Mouse Model are used in the study 'Dietary fish oil suppresses experimental immunoglobulin a nephropathy in mice.' (Pestka JJ et al., 2002).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with Vomitoxin

Download all related citations
Per page 10 20 50 100 | Total 1588
Authors Title Published Journal PubMed Link
Megalla SE et al. Production of deoxynivalenol and zearalenone by isolates of Fusarium graminearum Schw. 1986 J. Basic Microbiol. pmid:2951515
Völkl A et al. Microbial detoxification of mycotoxin deoxynivalenol. 2004 J. Basic Microbiol. pmid:15069674
Boeira LS et al. The effect of combinations of Fusarium mycotoxins (deoxynivalenol, zearalenone and fumonisin B1) on growth of brewing yeasts. 2000 J. Appl. Microbiol. pmid:10747219
González Pereyra ML et al. Fungi and selected mycotoxins from pre- and postfermented corn silage. 2008 J. Appl. Microbiol. pmid:18005347
Horevaj P et al. A real-time qPCR assay to quantify Fusarium graminearum biomass in wheat kernels. 2011 J. Appl. Microbiol. pmid:21645182
Franco TS et al. Lactic acid bacteria in the inhibition of Fusarium graminearum and deoxynivalenol detoxification. 2011 J. Appl. Microbiol. pmid:21672097
Aristimuño Ficoseco ME et al. Antifungal and antimycotoxigenic metabolites in Anacardiaceae species from northwest Argentina: isolation, identification and potential for control of Fusarium species. 2014 J. Appl. Microbiol. pmid:24428333
Velluti A et al. Impact of essential oils on growth rate, zearalenone and deoxynivalenol production by Fusarium graminearum under different temperature and water activity conditions in maize grain. 2004 J. Appl. Microbiol. pmid:15012810
Dorn B et al. Fusarium species complex and mycotoxins in grain maize from maize hybrid trials and from grower's fields. 2011 J. Appl. Microbiol. pmid:21714835
He J et al. Concurrent selection for microbial suppression of Fusarium graminearum, Fusarium head blight and deoxynivalenol in wheat. 2009 J. Appl. Microbiol. pmid:19298518
Stepień Ł et al. Wheat-infecting Fusarium species in Poland--their chemotypes and frequencies revealed by PCR assay. 2008 J. Appl. Genet. pmid:19029692
O'Neill K et al. The influence of gamma radiation and substrate on mycotoxin production by Fusarium culmorum IMI 309344. 1996 J. Appl. Bacteriol. pmid:8939030
Wuchiyama J et al. A trichothecene efflux pump encoded by Tri102 in the biosynthesis gene cluster of Fusarium graminearum. 2000 J. Antibiot. pmid:10805582
Russell L et al. Incidence of molds and mycotoxins in commercial animal feed mills in seven midwestern states, 1988-1989. 1991 J. Anim. Sci. pmid:1825995
Frobose HL et al. The progression of deoxynivalenol-induced growth suppression in nursery pigs and the potential of an algae-modified montmorillonite clay to mitigate these effects. 2016 J. Anim. Sci. pmid:27898884
Xiao H et al. Effects of composite antimicrobial peptides in weanling piglets challenged with deoxynivalenol: I. Growth performance, immune function, and antioxidation capacity. 2013 J. Anim. Sci. pmid:23965387
Xiao H et al. Effects of composite antimicrobial peptides in weanling piglets challenged with deoxynivalenol: II. Intestinal morphology and function. 2013 J. Anim. Sci. pmid:23965392
He P et al. Microbially detoxified vomitoxin-contaminated corn for young pigs. 1993 J. Anim. Sci. pmid:8478296
Swamy HV et al. Effects of feeding blends of grains naturally contaminated with Fusarium mycotoxins on brain regional neurochemistry of starter pigs and broiler chickens. 2004 J. Anim. Sci. pmid:15309961
Xiao H et al. Metabolic profiles in the response to supplementation with composite antimicrobial peptides in piglets challenged with deoxynivalenol. 2015 J. Anim. Sci. pmid:26020888
Frobose HL et al. The effects of deoxynivalenol-contaminated corn dried distillers grains with solubles in nursery pig diets and potential for mitigation by commercially available feed additives. 2015 J. Anim. Sci. pmid:26020884
Young LG et al. Vomitoxin in corn fed to young pigs. 1983 J. Anim. Sci. pmid:6630099
Richard JL et al. Analysis of naturally occurring mycotoxins in feedstuffs and food. 1993 J. Anim. Sci. pmid:8407669
Patience JF et al. Evaluation of two mycotoxin mitigation strategies in grow-finish swine diets containing corn dried distillers grains with solubles naturally contaminated with deoxynivalenol. 2014 J. Anim. Sci. pmid:24398837
Smith TK et al. Effect of feeding blends of Fusarium mycotoxin-contaminated grains containing deoxynivalenol and fusaric acid on growth and feed consumption of immature swine. 1997 J. Anim. Sci. pmid:9263067
Hughes DM et al. Overt signs of toxicity to dogs and cats of dietary deoxynivalenol. 1999 J. Anim. Sci. pmid:10229366
Chaytor AC et al. Effects of chronic exposure of diets with reduced concentrations of aflatoxin and deoxynivalenol on growth and immune status of pigs. 2011 J. Anim. Sci. pmid:20889686
Diekman MA and Green ML Mycotoxins and reproduction in domestic livestock. 1992 J. Anim. Sci. pmid:1388147
Huff WE et al. Mycotoxin interactions in poultry and swine. 1988 J. Anim. Sci. pmid:3170377
Díaz-Llano G and Smith TK Effects of feeding grains naturally contaminated with Fusarium mycotoxins with and without a polymeric glucomannan mycotoxin adsorbent on reproductive performance and serum chemistry of pregnant gilts. 2006 J. Anim. Sci. pmid:16908638
Klunker LR et al. Deoxynivalenol and E.coli lipopolysaccharide alter epithelial proliferation and spatial distribution of apical junction proteins along the small intestinal axis. 2013 J. Anim. Sci. pmid:23100596
Pollmann DS et al. Deoxynivalenol-contaminated wheat in swine diets. 1985 J. Anim. Sci. pmid:3972745
Price WD et al. Naturally occurring toxins in feedstuffs: Center for Veterinary Medicine Perspective. 1993 J. Anim. Sci. pmid:8407668
Accensi F et al. Ingestion of low doses of deoxynivalenol does not affect hematological, biochemical, or immune responses of piglets. 2006 J. Anim. Sci. pmid:16775078
Lun AK et al. The effects of vomitoxin and feed intake on the performance and blood characteristics of young pigs. 1985 J. Anim. Sci. pmid:4077764
Trenholm HL et al. Feeding trials with vomitoxin (deoxynivalenol)-contaminated wheat: effects on swine, poultry, and dairy cattle. 1984 J. Am. Vet. Med. Assoc. pmid:6480467
Schwartz HE et al. Characterization of three deoxynivalenol sulfonates formed by reaction of deoxynivalenol with sulfur reagents. 2013 J. Agric. Food Chem. pmid:23964860
Clifford LJ et al. An improved method for the purification of the trichothecene deoxynivalenol (vomitoxin) from Fusarium graminearum culture. 2003 J. Agric. Food Chem. pmid:12517120
Boudra H and Morgavi DP Reduction in fusarium toxin levels in corn silage with low dry matter and storage time. 2008 J. Agric. Food Chem. pmid:18498169
House JD et al. Deoxynivalenol removal from barley intended as swine feed through the use of an abrasive pearling procedure. 2003 J. Agric. Food Chem. pmid:12903987
Desjardins AE et al. Gibberella ear rot of maize (Zea mays) in Nepal: distribution of the mycotoxins nivalenol and deoxynivalenol in naturally and experimentally infected maize. 2008 J. Agric. Food Chem. pmid:18533662
Neuhof T et al. Distribution of trichothecenes, zearalenone, and ergosterol in a fractionated wheat harvest lot. 2008 J. Agric. Food Chem. pmid:18642928
Meneely J et al. Rapid surface plasmon resonance immunoassay for the determination of deoxynivalenol in wheat, wheat products, and maize-based baby food. 2010 J. Agric. Food Chem. pmid:23654230
Malachova A et al. Deoxynivalenol, deoxynivalenol-3-glucoside, and enniatins: the major mycotoxins found in cereal-based products on the Czech market. 2011 J. Agric. Food Chem. pmid:22070284
Zhang X et al. Multiplex Lateral Flow Immunoassays Based on Amorphous Carbon Nanoparticles for Detecting Three Fusarium Mycotoxins in Maize. 2017 J. Agric. Food Chem. pmid:28825819
Kostelanska M et al. Effects of milling and baking technologies on levels of deoxynivalenol and its masked form deoxynivalenol-3-glucoside. 2011 J. Agric. Food Chem. pmid:21797213
Yoshinari T et al. Structural determination of a nivalenol glucoside and development of an analytical method for the simultaneous determination of nivalenol and deoxynivalenol, and their glucosides, in wheat. 2014 J. Agric. Food Chem. pmid:24433151
Zhang Y and Caupert J Survey of mycotoxins in U.S. distiller's dried grains with solubles from 2009 to 2011. 2012 J. Agric. Food Chem. pmid:22148386
Wu Q et al. Impact of physicochemical parameters on the decomposition of deoxynivalenol during extrusion cooking of wheat grits. 2011 J. Agric. Food Chem. pmid:22010947
Stanic A et al. Nucleophilic Addition of Thiols to Deoxynivalenol. 2015 J. Agric. Food Chem. pmid:26242781
Bucheli TD et al. Fusarium mycotoxins: overlooked aquatic micropollutants? 2008 J. Agric. Food Chem. pmid:18197623
Cirillo T et al. Evaluation of conventional and organic italian foodstuffs for deoxynivalenol and fumonisins B(1) and B(2). 2003 J. Agric. Food Chem. pmid:14690407
Champeil A et al. Effects of grain sampling procedures on fusarium mycotoxin assays in wheat grains. 2004 J. Agric. Food Chem. pmid:15453665
Zhou B et al. Doehlert matrix design for optimization of the determination of bound deoxynivalenol in barley grain with trifluoroacetic acid (TFA). 2007 J. Agric. Food Chem. pmid:18004804
Sypecka Z et al. Deoxynivalenol and zearalenone residues in eggs of laying hens fed with a naturally contaminated diet: effects on egg production and estimation of transmission rates from feed to eggs. 2004 J. Agric. Food Chem. pmid:15315386
Hart LP and Braselton WE Distribution of vomitoxin in dry milled fractions of wheat infected with Gibberella zeae. 1983 May-Jun J. Agric. Food Chem. pmid:6886223
Tangni EK et al. Cross-reactivity of antibodies in some commercial deoxynivalenol test kits against some fusariotoxins. 2010 J. Agric. Food Chem. pmid:21087038
Qiang Z et al. Efficacy of a mycotoxin binder against dietary fumonisin, deoxynivalenol, and zearalenone in rats. 2011 J. Agric. Food Chem. pmid:21650453
Zachariasova M et al. Deoxynivalenol oligoglycosides: new "masked" fusarium toxins occurring in malt, beer, and breadstuff. 2012 J. Agric. Food Chem. pmid:22897145
Suzuki T and Iwahashi Y Comprehensive gene expression analysis of type B trichothecenes. 2012 J. Agric. Food Chem. pmid:22897823
Dyer RB et al. Fusarium graminearum TRI14 is required for high virulence and DON production on wheat but not for DON synthesis in vitro. 2005 J. Agric. Food Chem. pmid:16277434
Yaguchi A et al. Isolation and identification of precocenes and piperitone from essential oils as specific inhibitors of trichothecene production by Fusarium graminearum. 2009 J. Agric. Food Chem. pmid:19191669
Cooney JM et al. Impact of competitive fungi on Trichothecene production by Fusarium graminearum. 2001 J. Agric. Food Chem. pmid:11170621
Kostelanska M et al. Occurrence of deoxynivalenol and its major conjugate, deoxynivalenol-3-glucoside, in beer and some brewing intermediates. 2009 J. Agric. Food Chem. pmid:19301815
Liu Y et al. Solvolysis procedures for the determination of bound residues of the mycotoxin deoxynivalenol in fusarium species infected grain of two winter wheat cultivars preinfected with barley yellow dwarf virus. 2005 J. Agric. Food Chem. pmid:16104812
Maragos CM and Plattner RD Rapid fluorescence polarization immunoassay for the mycotoxin deoxynivalenol in wheat. 2002 J. Agric. Food Chem. pmid:11902919
Berthiller F et al. Masked mycotoxins: determination of a deoxynivalenol glucoside in artificially and naturally contaminated wheat by liquid chromatography-tandem mass spectrometry. 2005 J. Agric. Food Chem. pmid:15853382
Bretz M et al. Thermal degradation of the Fusarium mycotoxin deoxynivalenol. 2006 J. Agric. Food Chem. pmid:16910743
Cetin Y and Bullerman LB Confirmation of reduced toxicity of deoxynivalenol in extrusion-processed corn grits by the MTT bioassay. 2006 J. Agric. Food Chem. pmid:16506858
Uhlig S et al. Enzyme-assisted synthesis and structural characterization of the 3-, 8-, and 15-glucuronides of deoxynivalenol. 2013 J. Agric. Food Chem. pmid:23374009
Havlová P et al. The effect of fungicidal treatment on selected quality parameters of barley and malt. 2006 J. Agric. Food Chem. pmid:16478260
Wei W et al. Simultaneous determination of masked deoxynivalenol and some important type B trichothecenes in Chinese corn kernels and corn-based products by ultra-performance liquid chromatography-tandem mass spectrometry. 2012 J. Agric. Food Chem. pmid:23116247
Turner PC et al. Determinants of urinary deoxynivalenol and de-epoxy deoxynivalenol in male farmers from Normandy, France. 2010 J. Agric. Food Chem. pmid:20349912
Sanders M et al. Sampling of wheat dust and subsequent analysis of deoxynivalenol by LC-MS/MS. 2013 J. Agric. Food Chem. pmid:23782015
Tüdös AJ et al. Rapid surface plasmon resonance-based inhibition assay of deoxynivalenol. 2003 J. Agric. Food Chem. pmid:13129282
Liu DW et al. Potential natural exposure of endangered red-crowned crane (Grus japonensis) to mycotoxins aflatoxin B1, deoxynivalenol, zearalenone, T-2 toxin, and ochratoxin A. 2016 J Zhejiang Univ Sci B pmid:26834016
Goyarts T et al. On the effects of a chronic deoxynivalenol intoxication on performance, haematological and serum parameters of pigs when diets are offered either for ad libitum consumption or fed restrictively. 2005 J Vet Med A Physiol Pathol Clin Med pmid:16050913
Ngampongsa S et al. Arrhythmias and alterations in autonomic nervous function induced by deoxynivalenol (DON) in unrestrained rats. 2011 J Toxicol Sci pmid:21804309
Sugiyama K et al. NF-κB activation via MyD88-dependent Toll-like receptor signaling is inhibited by trichothecene mycotoxin deoxynivalenol. 2016 J Toxicol Sci pmid:26961612
Toyotome T et al. MEIS3 is repressed in A549 lung epithelial cells by deoxynivalenol and the repression contributes to the deleterious effect. 2016 J Toxicol Sci pmid:26763390
Wu W and Zhang H Role of tumor necrosis factor-α and interleukin-1β in anorexia induction following oral exposure to the trichothecene deoxynivalenol (vomitoxin) in the mouse. 2014 J Toxicol Sci pmid:25392278
Ngampongsa S et al. Toxic effects of T-2 toxin and deoxynivalenol on the mitochondrial electron transport system of cardiomyocytes in rats. 2013 J Toxicol Sci pmid:23719927
Robert H et al. Impact of mycotoxins on the intestine: are mucus and microbiota new targets? 2017 J Toxicol Environ Health B Crit Rev pmid:28636450
Pestka JJ and Smolinski AT Deoxynivalenol: toxicology and potential effects on humans. 2005 Jan-Feb J Toxicol Environ Health B Crit Rev pmid:15762554
Rotter BA et al. Investigations in the use of mice exposed to mycotoxins as a model for growing pigs. 1992 J Toxicol Environ Health pmid:1404488
Greene DM et al. Role of gender and strain in vomitoxin-induced dysregulation of IgA production and IgA nephropathy in the mouse. 1994 J Toxicol Environ Health pmid:8078091
Rotter BA et al. Toxicology of deoxynivalenol (vomitoxin). 1996 J Toxicol Environ Health pmid:8637056
Cunha SC and Fernandes JO Development and validation of a method based on a QuEChERS procedure and heart-cutting GC-MS for determination of five mycotoxins in cereal products. 2010 J Sep Sci pmid:20155747
Han Z et al. A rapid method with ultra-high-performance liquid chromatography-tandem mass spectrometry for simultaneous determination of five type B trichothecenes in traditional Chinese medicines. 2010 J Sep Sci pmid:20533344
Schmidt-Heydt M et al. Modelling the relationship between environmental factors, transcriptional genes and deoxynivalenol mycotoxin production by strains of two Fusarium species. 2011 J R Soc Interface pmid:20462881
Osman AM et al. Protein expression profiling of mouse thymoma cells upon exposure to the trichothecene deoxynivalenol (DON): implications for its mechanism of action. 2010 Jul-Sep J Immunotoxicol pmid:20672443
Pleadin J et al. Correlation of deoxynivalenol and fumonisin concentration determined in maize by ELISA methods. 2012 J Immunoassay Immunochem pmid:22963490
Wang S et al. Construction of multiform scFv antibodies using linker peptide. 2008 J Genet Genomics pmid:18499076
Turner PC et al. Dietary wheat reduction decreases the level of urinary deoxynivalenol in UK adults. 2008 J Expo Sci Environ Epidemiol pmid:17940556
Kolesarova A et al. The influence of deoxynivalenol and zearalenone on steroid hormone production by porcine ovarian granulosa cells in vitro. 2017 J Environ Sci Health B pmid:28945498
Prelusky DB The effect of deoxynivalenol on serotoninergic neurotransmitter levels in pig blood. 1994 J Environ Sci Health B pmid:7527434
Prelusky DB et al. Nontransmission of deoxynivalenol (vomitoxin) to milk following oral administration to dairy cows. 1984 J Environ Sci Health B pmid:6501791
Rotter BA et al. The role of tryptophan in DON-induced feed rejection. 1996 J Environ Sci Health B pmid:8896360
Prelusky DB et al. Effect of the appetite stimulant cyproheptadine on deoxynivalenol-induced reductions in feed consumption and weight gain in the mouse. 1997 J Environ Sci Health B pmid:9177014
Prelusky DB et al. Plasma pharmacokinetics of the mycotoxin deoxynivalenol following oral and intravenous administration to sheep. 1985 J Environ Sci Health B pmid:4093544