| MeSH term | MeSH ID | Detail |
|---|---|---|
| Body Weight | D001835 | 333 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Hemolysis | D006461 | 131 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
| Weight Loss | D015431 | 56 associated lipids |
| Precancerous Conditions | D011230 | 48 associated lipids |
| Hyperplasia | D006965 | 34 associated lipids |
| Obesity | D009765 | 29 associated lipids |
| Stomach Neoplasms | D013274 | 24 associated lipids |
| Poultry Diseases | D011201 | 21 associated lipids |
| Esophageal Neoplasms | D004938 | 20 associated lipids |
| Mycoses | D009181 | 18 associated lipids |
| Swine Diseases | D013553 | 16 associated lipids |
| Thymus Neoplasms | D013953 | 15 associated lipids |
| Fetal Resorption | D005327 | 15 associated lipids |
| Hematuria | D006417 | 13 associated lipids |
| Fetal Weight | D020567 | 12 associated lipids |
| Immune Complex Diseases | D007105 | 9 associated lipids |
Vomitoxin
Vomitoxin is a lipid of Prenol Lipids (PR) class. Vomitoxin is associated with abnormalities such as Infection and Gastroenteritis. The involved functions are known as mRNA Expression, Inflammation, Transcription, Genetic, Protein Biosynthesis and Adverse effects. Vomitoxin often locates in Lymphoid Tissue, Immune system, Bone Marrow and Plasma membrane. The associated genes with Vomitoxin are IMPACT gene, HIST1H1C gene and RBM39 gene. The related experimental models are Mouse Model.
Cross Reference
Introduction
To understand associated biological information of Vomitoxin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Vomitoxin?
Vomitoxin is suspected in Infection, Gastroenteritis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Vomitoxin
PubChem Associated disorders and diseases
What pathways are associated with Vomitoxin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Vomitoxin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Vomitoxin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Vomitoxin?
There are no associated biomedical information in the current reference collection.
What genes are associated with Vomitoxin?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Vomitoxin?
Mouse Model
Mouse Model are used in the study 'Dietary fish oil suppresses experimental immunoglobulin a nephropathy in mice.' (Pestka JJ et al., 2002).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Vomitoxin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Chung YJ et al. | Up-regulation of macrophage inflammatory protein-2 and complement 3A receptor by the trichothecenes deoxynivalenol and satratoxin G. | 2003 | Toxicology | pmid:12604170 |
| Savard C et al. | Prevention of deoxynivalenol- and zearalenone-associated oxidative stress does not restore MA-10 Leydig cell functions. | 2016 | Toxicology | pmid:26783879 |
| Amuzie CJ et al. | Tissue distribution and proinflammatory cytokine induction by the trichothecene deoxynivalenol in the mouse: comparison of nasal vs. oral exposure. | 2008 | Toxicology | pmid:18433975 |
| Ji GE et al. | Modulation of nitric oxide, hydrogen peroxide and cytokine production in a clonal macrophage model by the trichothecene vomitoxin (deoxynivalenol). | 1998 | Toxicology | pmid:9570333 |
| Pestka JJ et al. | Induction of apoptosis and cytokine production in the Jurkat human T cells by deoxynivalenol: role of mitogen-activated protein kinases and comparison to other 8-ketotrichothecenes. | 2005 | Toxicology | pmid:15588914 |
| Mikami O et al. | Porcine hepatocyte apoptosis and reduction of albumin secretion induced by deoxynivalenol. | 2004 | Toxicology | pmid:15388250 |
| Robbana-Barnat S et al. | Immunosuppressive properties of deoxynivalenol. | 1988 | Toxicology | pmid:3257592 |
| Moon Y and Pestka JJ | Vomitoxin-induced cyclooxygenase-2 gene expression in macrophages mediated by activation of ERK and p38 but not JNK mitogen-activated protein kinases. | 2002 | Toxicol. Sci. | pmid:12377986 |
| Bae H et al. | Hematopoietic cell kinase associates with the 40S ribosomal subunit and mediates the ribotoxic stress response to deoxynivalenol in mononuclear phagocytes. | 2010 | Toxicol. Sci. | pmid:20181660 |
| Bae HK and Pestka JJ | Deoxynivalenol induces p38 interaction with the ribosome in monocytes and macrophages. | 2008 | Toxicol. Sci. | pmid:18502741 |
| Li M and Pestka JJ | Comparative induction of 28S ribosomal RNA cleavage by ricin and the trichothecenes deoxynivalenol and T-2 toxin in the macrophage. | 2008 | Toxicol. Sci. | pmid:18535001 |
| Gray JS et al. | Double-stranded RNA-activated protein kinase mediates induction of interleukin-8 expression by deoxynivalenol, Shiga toxin 1, and ricin in monocytes. | 2008 | Toxicol. Sci. | pmid:18599499 |
| Zhou HR et al. | Lipopolysaccharide and the trichothecene vomitoxin (deoxynivalenol) synergistically induce apoptosis in murine lymphoid organs. | 2000 | Toxicol. Sci. | pmid:10696773 |
| Girardet C et al. | Central inflammation and sickness-like behavior induced by the food contaminant deoxynivalenol: a PGE2-independent mechanism. | 2011 | Toxicol. Sci. | pmid:21873375 |
| Park SH et al. | Chronic Nod2 stimulation potentiates activating transcription factor 3 and paradoxical superinduction of epithelial proinflammatory chemokines by mucoactive ribotoxic stressors via RNA-binding protein human antigen R. | 2012 | Toxicol. Sci. | pmid:22003189 |
| Pinton P et al. | Toxicity of deoxynivalenol and its acetylated derivatives on the intestine: differential effects on morphology, barrier function, tight junction proteins, and mitogen-activated protein kinases. | 2012 | Toxicol. Sci. | pmid:22859312 |
| Zhou HR et al. | Induction of competing apoptotic and survival signaling pathways in the macrophage by the ribotoxic trichothecene deoxynivalenol. | 2005 | Toxicol. Sci. | pmid:15976193 |
| Li M et al. | Modulation of murine host response to enteric reovirus infection by the trichothecene deoxynivalenol. | 2005 | Toxicol. Sci. | pmid:15958657 |
| Li M et al. | Deoxynivalenol exacerbates viral bronchopneumonia induced by respiratory reovirus infection. | 2007 | Toxicol. Sci. | pmid:17090620 |
| Voss KA | A new perspective on deoxynivalenol and growth suppression. | 2010 | Toxicol. Sci. | pmid:19933702 |