Vomitoxin

Vomitoxin is a lipid of Prenol Lipids (PR) class. Vomitoxin is associated with abnormalities such as Infection and Gastroenteritis. The involved functions are known as mRNA Expression, Inflammation, Transcription, Genetic, Protein Biosynthesis and Adverse effects. Vomitoxin often locates in Lymphoid Tissue, Immune system, Bone Marrow and Plasma membrane. The associated genes with Vomitoxin are IMPACT gene, HIST1H1C gene and RBM39 gene. The related experimental models are Mouse Model.

Cross Reference

Introduction

To understand associated biological information of Vomitoxin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Vomitoxin?

Vomitoxin is suspected in Infection, Gastroenteritis and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Vomitoxin

MeSH term MeSH ID Detail
Anorexia D000855 8 associated lipids
Ascaridiasis D001198 1 associated lipids
Body Weight D001835 333 associated lipids
Bronchopneumonia D001996 7 associated lipids
Edema D004487 152 associated lipids
Esophageal Neoplasms D004938 20 associated lipids
Fetal Resorption D005327 15 associated lipids
Glomerulonephritis, IGA D005922 7 associated lipids
Hematuria D006417 13 associated lipids
Hemolysis D006461 131 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hyperplasia D006965 34 associated lipids
Immune Complex Diseases D007105 9 associated lipids
Inflammation D007249 119 associated lipids
Mycoses D009181 18 associated lipids
Obesity D009765 29 associated lipids
Poultry Diseases D011201 21 associated lipids
Precancerous Conditions D011230 48 associated lipids
Splenic Diseases D013158 5 associated lipids
Stomach Neoplasms D013274 24 associated lipids
Per page 10 20 50 | Total 29

PubChem Associated disorders and diseases

What pathways are associated with Vomitoxin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Vomitoxin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Vomitoxin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Vomitoxin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Vomitoxin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Vomitoxin?

Mouse Model

Mouse Model are used in the study 'Dietary fish oil suppresses experimental immunoglobulin a nephropathy in mice.' (Pestka JJ et al., 2002).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Vomitoxin

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Per page 10 20 50 100 | Total 1588
Authors Title Published Journal PubMed Link
Dänicke S et al. Investigations on the kinetics of the concentration of deoxynivalenol (DON) and on spoilage by moulds and yeasts of wheat grain preserved with sodium metabisulfite (Na2S2O5, SBS) and propionic acid at various moisture contents. 2010 Arch Anim Nutr pmid:20578648
Wang CR and Chu FS Production and characterization of antibodies against nivalenol tetraacetate. 1991 Appl. Environ. Microbiol. pmid:2059030
Kadota T et al. Rapid detection of nivalenol and deoxynivalenol in wheat using surface plasmon resonance immunoassay. 2010 Anal. Chim. Acta pmid:20599032
Baldwin TK et al. A partial chromosomal deletion caused by random plasmid integration resulted in a reduced virulence phenotype in Fusarium graminearum. 2010 Mol. Plant Microbe Interact. pmid:20615118
Wada K et al. Effects of mycotoxins on chemiluminescent response and cytokine mRNA expression of bovine neutrophils. 2010 J. Vet. Med. Sci. pmid:20622479
Yoshida M and Nakajima T Deoxynivalenol and nivalenol accumulation in wheat infected with Fusarium graminearum during grain development. 2010 Phytopathology pmid:20626280
Van De Walle J et al. Physio-pathological parameters affect the activation of inflammatory pathways by deoxynivalenol in Caco-2 cells. 2010 Toxicol In Vitro pmid:20633634
Malovrh T and Jakovac-Strajn B Feed contaminated with Fusarium toxins alter lymphocyte proliferation and apoptosis in primiparous sows during the perinatal period. 2010 Food Chem. Toxicol. pmid:20654678
Osman AM et al. Protein expression profiling of mouse thymoma cells upon exposure to the trichothecene deoxynivalenol (DON): implications for its mechanism of action. 2010 Jul-Sep J Immunotoxicol pmid:20672443
Dänicke S et al. Effects of oral exposure of pigs to deoxynivalenol (DON) sulfonate (DONS) as the non-toxic derivative of DON on tissue residues of DON and de-epoxy-DON and on DONS blood levels. 2010 Food Addit Contam Part A Chem Anal Control Expo Risk Assess pmid:20677033
Beyer M et al. Estimating deoxynivalenol contents of wheat samples containing different levels of Fusarium-damaged kernels by diffuse reflectance spectrometry and partial least square regression. 2010 Int. J. Food Microbiol. pmid:20678823
Casteel M et al. Impact of DUSP1 on the apoptotic potential of deoxynivalenol in the epithelial cell line HepG2. 2010 Toxicol. Lett. pmid:20708668
Faixová Z et al. Effects of feeding diets contaminated with Fusarium mycotoxins on blood biochemical parameters of broiler chickens. 2010 Acta Vet. Hung. pmid:20713319
Lepom P et al. [Occurrence of Fusarium strains and their mycotoxins in corn silage. 7. Formation of deoxynivalenol (DON) in a silage corn plot artificially inoculated with Fusarium culmorum and the effect of silaging on the stability of the DON formed]. 1990 Arch Tierernahr pmid:2076050
Pestka JJ Deoxynivalenol: mechanisms of action, human exposure, and toxicological relevance. 2010 Arch. Toxicol. pmid:20798930
Sahu SC et al. Comparative hepatotoxicity of deoxynivalenol in rat, mouse and human liver cells in culture. 2010 J Appl Toxicol pmid:20809545
Puri KD and Zhong S The 3ADON population of Fusarium graminearum found in North Dakota is more aggressive and produces a higher level of DON than the prevalent 15ADON population in spring wheat. 2010 Phytopathology pmid:20839936
Ikunaga Y et al. Nocardioides sp. strain WSN05-2, isolated from a wheat field, degrades deoxynivalenol, producing the novel intermediate 3-epi-deoxynivalenol. 2011 Appl. Microbiol. Biotechnol. pmid:20857291
Pinton P et al. Deoxynivalenol impairs porcine intestinal barrier function and decreases the protein expression of claudin-4 through a mitogen-activated protein kinase-dependent mechanism. 2010 J. Nutr. pmid:20861219
Jia H et al. Quantitative trait loci conferring resistance to Fusarium head blight in barley respond differentially to Fusarium graminearum infection. 2011 Funct. Integr. Genomics pmid:20865292
Park SH et al. Repression of peroxisome proliferator-activated receptor gamma by mucosal ribotoxic insult-activated CCAAT/enhancer-binding protein homologous protein. 2010 J. Immunol. pmid:20889551
Chaytor AC et al. Effects of chronic exposure of diets with reduced concentrations of aflatoxin and deoxynivalenol on growth and immune status of pigs. 2011 J. Anim. Sci. pmid:20889686
Trucksess MW et al. Determination of deoxynivalenol in processed foods. 2010 Jul-Aug J AOAC Int pmid:20922957
Turner PC et al. Assessment of deoxynivalenol metabolite profiles in UK adults. 2011 Food Chem. Toxicol. pmid:20934480
NumanoÄŸlu E et al. Multiple-stage extraction strategy for the determination of deoxynivalenol in maize. 2011 Food Addit Contam Part A Chem Anal Control Expo Risk Assess pmid:20936556
Voss KA and Snook ME Stability of the mycotoxin deoxynivalenol (DON) during the production of flour-based foods and wheat flake cereal. 2010 Food Addit Contam Part A Chem Anal Control Expo Risk Assess pmid:20936557
Diesing AK et al. Mycotoxin deoxynivalenol (DON) mediates biphasic cellular response in intestinal porcine epithelial cell lines IPEC-1 and IPEC-J2. 2011 Toxicol. Lett. pmid:20937367
Jin PG et al. Simultaneous determination of 10 mycotoxins in grain by ultra-high-performance liquid chromatography-tandem mass spectrometry using ¹³C₁₅-deoxynivalenol as internal standard. 2010 Food Addit Contam Part A Chem Anal Control Expo Risk Assess pmid:20938852
Zhang J et al. Simultaneous detection of deoxynivalenol and zearalenone by dual-label time-resolved fluorescence immunoassay. 2011 J. Sci. Food Agric. pmid:20945513
Pacheco GD et al. Phytic acid protects porcine intestinal epithelial cells from deoxynivalenol (DON) cytotoxicity. 2012 Exp. Toxicol. Pathol. pmid:20971622
Thammawong M et al. Distribution of deoxynivalenol and nivalenol in milling fractions from fusarium-infected Japanese wheat cultivars. 2010 J. Food Prot. pmid:21067669
van Kol SW et al. The effects of deoxynivalenol on gene expression in the murine thymus. 2011 Toxicol. Appl. Pharmacol. pmid:21074547
Tangni EK et al. Cross-reactivity of antibodies in some commercial deoxynivalenol test kits against some fusariotoxins. 2010 J. Agric. Food Chem. pmid:21087038
Nguyen LN et al. Autophagy-related lipase FgATG15 of Fusarium graminearum is important for lipid turnover and plant infection. 2011 Fungal Genet. Biol. pmid:21094265
He CH et al. The individual and combined effects of deoxynivalenol and aflatoxin B₁on primary hepatocytes of Cyprinus carpio. 2010 Int J Mol Sci pmid:21152299
Khatibi PA et al. Bioprospecting for trichothecene 3-O-acetyltransferases in the fungal genus Fusarium yields functional enzymes with different abilities to modify the mycotoxin deoxynivalenol. 2011 Appl. Environ. Microbiol. pmid:21169453
Gardiner DM et al. Early activation of wheat polyamine biosynthesis during Fusarium head blight implicates putrescine as an inducer of trichothecene mycotoxin production. 2010 BMC Plant Biol. pmid:21192794
Mikami O et al. The effects of acute exposure to deoxynivalenol on some inflammatory parameters in miniature pigs. 2011 J. Vet. Med. Sci. pmid:21224530
Ámbrus A et al. Exposure of consumers to deoxynivalenol from consumption of white bread in Hungary. 2011 Food Addit Contam Part A Chem Anal Control Expo Risk Assess pmid:21253986
Grenier B et al. Individual and combined effects of subclinical doses of deoxynivalenol and fumonisins in piglets. 2011 Mol Nutr Food Res pmid:21259430
Eggert K and Pawelzik E Proteome analysis of Fusarium head blight in grains of naked barley (Hordeum vulgare subsp. nudum). 2011 Proteomics pmid:21271677
Skládanka J et al. Forage as a primary source of mycotoxins in animal diets. 2011 Int J Environ Res Public Health pmid:21318013
Reynoso MM et al. Trichothecene genotypes and chemotypes in Fusarium graminearum strains isolated from wheat in Argentina. 2011 Int. J. Food Microbiol. pmid:21320729
Nakatani Y et al. Simulation of deoxynivalenol intake from wheat consumption in Japan using the Monte Carlo method. 2011 Food Addit Contam Part A Chem Anal Control Expo Risk Assess pmid:21331965
Diesing AK et al. Vulnerability of polarised intestinal porcine epithelial cells to mycotoxin deoxynivalenol depends on the route of application. 2011 PLoS ONE pmid:21364771
Lattanzio VM et al. LC-MS/MS characterization of the urinary excretion profile of the mycotoxin deoxynivalenol in human and rat. 2011 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:21367675
Ponts N et al. Cinnamic-derived acids significantly affect Fusarium graminearum growth and in vitro synthesis of type B trichothecenes. 2011 Phytopathology pmid:21405995
Sobolev VS et al. [The contamination of the 1986-1988 wheat harvests with deoxynivalenol (vomitoxin)]. 1990 Jan-Feb Vopr Pitan pmid:2140639
Li FQ et al. [Natural occurrence of masked deoxynivalenol and multi-mycotoxins in cereals from China harvested in 2007 and 2008]. 2011 Zhonghua Yu Fang Yi Xue Za Zhi pmid:21418821
Thammawong M et al. Distinct distribution of deoxynivalenol, nivalenol, and ergosterol in Fusarium-infected Japanese soft red winter wheat milling fractions. 2011 Mycopathologia pmid:21424857