Vomitoxin

Vomitoxin is a lipid of Prenol Lipids (PR) class. Vomitoxin is associated with abnormalities such as Infection and Gastroenteritis. The involved functions are known as mRNA Expression, Inflammation, Transcription, Genetic, Protein Biosynthesis and Adverse effects. Vomitoxin often locates in Lymphoid Tissue, Immune system, Bone Marrow and Plasma membrane. The associated genes with Vomitoxin are IMPACT gene, HIST1H1C gene and RBM39 gene. The related experimental models are Mouse Model.

Cross Reference

Introduction

To understand associated biological information of Vomitoxin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Vomitoxin?

Vomitoxin is suspected in Infection, Gastroenteritis and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Vomitoxin

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Inflammation D007249 119 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Esophageal Neoplasms D004938 20 associated lipids
Precancerous Conditions D011230 48 associated lipids
Stomach Neoplasms D013274 24 associated lipids
Hematuria D006417 13 associated lipids
Weight Gain D015430 101 associated lipids
Obesity D009765 29 associated lipids
Hyperplasia D006965 34 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Fetal Weight D020567 12 associated lipids
Immune Complex Diseases D007105 9 associated lipids
Glomerulonephritis, IGA D005922 7 associated lipids
Swine Diseases D013553 16 associated lipids
Poultry Diseases D011201 21 associated lipids
Thymus Neoplasms D013953 15 associated lipids
Bronchopneumonia D001996 7 associated lipids
Fetal Resorption D005327 15 associated lipids
Per page 10 20 50 | Total 29

PubChem Associated disorders and diseases

What pathways are associated with Vomitoxin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Vomitoxin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Vomitoxin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Vomitoxin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Vomitoxin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Vomitoxin?

Mouse Model

Mouse Model are used in the study 'Dietary fish oil suppresses experimental immunoglobulin a nephropathy in mice.' (Pestka JJ et al., 2002).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Vomitoxin

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Per page 10 20 50 100 | Total 1588
Authors Title Published Journal PubMed Link
Brera C et al. Exposure assessment for Italian population groups to deoxynivalenol deriving from pasta consumption. 2013 Toxins (Basel) pmid:24287568
Basso K et al. Deoxynivanelol and fumonisin, alone or in combination, induce changes on intestinal junction complexes and in E-cadherin expression. 2013 Toxins (Basel) pmid:24287571
Wilson NM et al. Modification of the Mycotoxin Deoxynivalenol Using Microorganisms Isolated from Environmental Samples. 2017 Toxins (Basel) pmid:28420137
Drakulic J et al. Contrasting Roles of Deoxynivalenol and Nivalenol in Host-Mediated Interactions between Fusarium graminearum and Sitobion avenae. 2016 Toxins (Basel) pmid:27916862
Alizadeh A et al. Deoxynivalenol and Its Modified Forms: Are There Major Differences? 2016 Toxins (Basel) pmid:27854268
Cirlini M et al. Durum wheat (Triticum Durum Desf.) lines show different abilities to form masked mycotoxins under greenhouse conditions. 2014 Toxins (Basel) pmid:24368326
Ovando-Martínez M et al. Analysis of deoxynivalenol and deoxynivalenol-3-glucoside in hard red spring wheat inoculated with Fusarium graminearum. 2013 Toxins (Basel) pmid:24351715
Simsek S et al. Occurrence of deoxynivalenol and deoxynivalenol-3-glucoside in hard red spring wheat grown in the USA. 2013 Toxins (Basel) pmid:24351720
Grenier B et al. Susceptibility of Broiler Chickens to Coccidiosis When Fed Subclinical Doses of Deoxynivalenol and Fumonisins-Special Emphasis on the Immunological Response and the Mycotoxin Interaction. 2016 Toxins (Basel) pmid:27472362
Audenaert K et al. Deoxynivalenol: a major player in the multifaceted response of Fusarium to its environment. 2014 Toxins (Basel) pmid:24451843
Giménez I et al. Effects of bread making and wheat germ addition on the natural deoxynivalenol content in bread. 2014 Toxins (Basel) pmid:24451845
Wiwart M et al. The Response of Selected Triticum spp. Genotypes with Different Ploidy Levels to Head Blight Caused by Fusarium culmorum (W.G.Smith) Sacc. 2016 Toxins (Basel) pmid:27092526
Sanders M et al. Comparison of Enzyme-Linked Immunosorbent Assay, Surface Plasmon Resonance and Biolayer Interferometry for Screening of Deoxynivalenol in Wheat and Wheat Dust. 2016 Toxins (Basel) pmid:27077883
Goossens J et al. Influence of mycotoxins and a mycotoxin adsorbing agent on the oral bioavailability of commonly used antibiotics in pigs. 2012 Toxins (Basel) pmid:22606377
Forrer HR et al. Fusarium head blight control and prevention of mycotoxin contamination in wheat with botanicals and tannic acid. 2014 Toxins (Basel) pmid:24577585
Waśkiewicz A et al. Deoxynivalenol in the gastrointestinal tract of immature gilts under per os toxin application. 2014 Toxins (Basel) pmid:24603665
Clark ES et al. High Sensitivity of Aged Mice to Deoxynivalenol (Vomitoxin)-Induced Anorexia Corresponds to Elevated Proinflammatory Cytokine and Satiety Hormone Responses. 2015 Toxins (Basel) pmid:26492270
Ali N et al. Deoxynivalenol Exposure Assessment for Pregnant Women in Bangladesh. 2015 Toxins (Basel) pmid:26404372
Schmeitzl C et al. The Metabolic Fate of Deoxynivalenol and Its Acetylated Derivatives in a Wheat Suspension Culture: Identification and Detection of DON-15-O-Glucoside, 15-Acetyl-DON-3-O-Glucoside and 15-Acetyl-DON-3-Sulfate. 2015 Toxins (Basel) pmid:26274975
Clark ES et al. Murine Anorectic Response to Deoxynivalenol (Vomitoxin) Is Sex-Dependent. 2015 Toxins (Basel) pmid:26230710
Generotti S et al. Deoxynivalenol & Deoxynivalenol-3-Glucoside Mitigation through Bakery Production Strategies: Effective Experimental Design within Industrial Rusk-Making Technology. 2015 Toxins (Basel) pmid:26213969
Michlmayr H et al. Biochemical Characterization of a Recombinant UDP-glucosyltransferase from Rice and Enzymatic Production of Deoxynivalenol-3-O-β-D-glucoside. 2015 Toxins (Basel) pmid:26197338
Alizadeh A et al. Deoxynivalenol Impairs Weight Gain and Affects Markers of Gut Health after Low-Dose, Short-Term Exposure of Growing Pigs. 2015 Toxins (Basel) pmid:26067367
Bryła M et al. Occurrence of 26 Mycotoxins in the Grain of Cereals Cultivated in Poland. 2016 Toxins (Basel) pmid:27231939
Paulick M et al. Effects of increasing concentrations of sodium sulfite on deoxynivalenol and deoxynivalenol sulfonate concentrations of maize kernels and maize meal preserved at various moisture content. 2015 Toxins (Basel) pmid:25760079
Ji F et al. Relationship of deoxynivalenol content in grain, chaff, and straw with Fusarium head blight severity in wheat varieties with various levels of resistance. 2015 Toxins (Basel) pmid:25751146
Rodríguez-Carrasco Y et al. Preliminary estimation of deoxynivalenol excretion through a 24 h pilot study. 2015 Toxins (Basel) pmid:25723325
Manda G et al. Dual effects exerted in vitro by micromolar concentrations of deoxynivalenol on undifferentiated caco-2 cells. 2015 Toxins (Basel) pmid:25690693
Antonissen G et al. Chronic exposure to deoxynivalenol has no influence on the oral bioavailability of fumonisin B1 in broiler chickens. 2015 Toxins (Basel) pmid:25690690
Zhou HR et al. Direct activation of ribosome-associated double-stranded RNA-dependent protein kinase (PKR) by deoxynivalenol, anisomycin and ricin: a new model for ribotoxic stress response induction. 2014 Toxins (Basel) pmid:25521494
Pinton P and Oswald IP Effect of deoxynivalenol and other Type B trichothecenes on the intestine: a review. 2014 Toxins (Basel) pmid:24859243
Moretti A et al. Systemic growth of F. graminearum in wheat plants and related accumulation of deoxynivalenol. 2014 Toxins (Basel) pmid:24727554
Pietsch C et al. Occurrence of deoxynivalenol and zearalenone in commercial fish feed: an initial study. 2013 Toxins (Basel) pmid:23325300
Mesterházy A et al. Role of fungicides, application of nozzle types, and the resistance level of wheat varieties in the control of Fusarium head blight and deoxynivalenol. 2011 Toxins (Basel) pmid:22174980
Gajęcka M et al. The expression of type-1 and type-2 nitric oxide synthase in selected tissues of the gastrointestinal tract during mixed mycotoxicosis. 2013 Toxins (Basel) pmid:24284830
Awad W et al. The toxicological impacts of the Fusarium mycotoxin, deoxynivalenol, in poultry flocks with special reference to immunotoxicity. 2013 Toxins (Basel) pmid:23628787
Weaver AC et al. Protective effect of two yeast based feed additives on pigs chronically exposed to deoxynivalenol and zearalenone. 2014 Toxins (Basel) pmid:25533517
Kim DH et al. Incidence and levels of deoxynivalenol, fumonisins and zearalenone contaminants in animal feeds used in Korea in 2012. 2014 Toxins (Basel) pmid:24366207
Waśkiewicz A et al. Deoxynivalenol and oxidative stress indicators in winter wheat inoculated with Fusarium graminearum. 2014 Toxins (Basel) pmid:24514944
Schollenberger M et al. Occurrence and distribution of 13 trichothecene toxins in naturally contaminated maize plants in Germany. 2012 Toxins (Basel) pmid:23162697
Sliková S et al. Occurrence of deoxynivalenol in wheat in Slovakia during 2010 and 2011. 2013 Toxins (Basel) pmid:23917334
Mthiyane DM and Mhlanga BS The nutritive value of marula (Sclerocarya birrea) seed cake for broiler chickens: nutritional composition, performance, carcass characteristics and oxidative and mycotoxin status. 2017 Trop Anim Health Prod pmid:28332071
Awad WA et al. Mechanisms underlying the inhibitory effect of the feed contaminant deoxynivalenol on glucose absorption in broiler chickens. 2014 Vet. J. pmid:25011710
Tiemann U et al. Changes in the spleen and liver of pregnant sows and full-term piglets after feeding diets naturally contaminated with deoxynivalenol and zearalenone. 2008 Vet. J. pmid:17434324
Moss MO Fusarial toxins: are they a cause for concern? 2003 Vet. J. pmid:12672361
Dänicke S et al. Ascaridia galli infection affects pullets differently when feed is contaminated with the Fusarium toxin deoxynivalenol (DON). 2013 Vet. Parasitol. pmid:24113465
Jakovac-Strajn B et al. Effects of a deoxynivalenol-contaminated diet on the reproductive performance and immunoglobulin concentrations in pigs. 2009 Vet. Rec. pmid:20008344
Gu MJ et al. Barrier protection via Toll-like receptor 2 signaling in porcine intestinal epithelial cells damaged by deoxynivalnol. 2016 Vet. Res. pmid:26857454
Vandenbroucke V et al. The mycotoxin deoxynivalenol promotes uptake of Salmonella Typhimurium in porcine macrophages, associated with ERK1/2 induced cytoskeleton reorganization. 2009 Nov-Dec Vet. Res. pmid:19674540
Severino L et al. Immune effects of four Fusarium-toxins (FB1, ZEA, NIV, DON) on the proliferation of Jurkat cells and porcine lymphocytes: in vitro study. 2008 Vet. Res. Commun. pmid:18683067
Bergsjø B et al. The effects of naturally deoxynivalenol-contaminated oats on the clinical condition, blood parameters, performance and carcass composition of growing pigs. 1993 Vet. Res. Commun. pmid:8146954
Tognon G et al. Implementation of the electronic nose for the identification of mycotoxins in durum wheat (Triticum durum). 2005 Vet. Res. Commun. pmid:16245002
Ferrari L et al. Cellular immune response and immunotoxicity induced by DON (deoxynivalenol) in piglets. 2009 Vet. Res. Commun. pmid:19578957
Zakharova LP et al. [Grain contamination by deoxynivalenol in Russia]. 1994 Vopr Pitan pmid:7975431
Tutel'ian VA et al. [A method of determining the levels of deoxynivalenol (vomitoxin) and its metabolites]. 1991 Sep-Oct Vopr Pitan pmid:1796578
Sobolev VS et al. [The contamination of the 1986-1988 wheat harvests with deoxynivalenol (vomitoxin)]. 1990 Jan-Feb Vopr Pitan pmid:2140639
Obol'skiÄ­ OL et al. [Effect of dietary selenium on the activity of UDP-glucuronosyltransferases and metabolism of mycotoxin deoxynivalenol in rats]. 1998 Vopr Pitan pmid:9825468
Sergeev IN et al. [The effect of the trichothecene mycotoxin deoxynivalenol (vomitoxin) on calcium homeostasis, vitamin D metabolism and receptors in rats]. 1990 Sep-Oct Vopr. Med. Khim. pmid:2174586
Wettstein FE and Bucheli TD Poor elimination rates in waste water treatment plants lead to continuous emission of deoxynivalenol into the aquatic environment. 2010 Water Res. pmid:20547404
Ji F et al. [Development of the monoclonal antibody to deoxynivalenol]. 2008 Wei Sheng Wu Xue Bao pmid:18837372
Wang H et al. [Effects of deoxynivalenol on proliferation and tumor necrosis factor-alpha secretion of human peripheral blood mononuclear cells in vitro]. 2000 Wei Sheng Yan Jiu pmid:12520964
Lin X et al. [Development of in vitro digestion model for assessing the bioaccessibility of deoxynivalenol derived from foods]. 2012 Wei Sheng Yan Jiu pmid:22443053
Liu J et al. [Effects of deoxynivalenol on apoptosis of human gastric carcinoma cell line SGC-7901, BGC-823 in vitro]. 2009 Wei Sheng Yan Jiu pmid:19689068
Wang H et al. [Effect of deoxynivalenol and aflatoxin G1 on apoptosis of human blood lymphocytes in vitro]. 1999 Wei Sheng Yan Jiu pmid:11938994
Yu C et al. [Study advance on formation, transformation and detection of masked deoxynivalenol]. 2009 Wei Sheng Yan Jiu pmid:19408673
Islam R et al. Aerobic and anaerobic de-epoxydation of mycotoxin deoxynivalenol by bacteria originating from agricultural soil. 2012 World J. Microbiol. Biotechnol. pmid:22806774
Worrell NR et al. The role of gut micro-organisms in the metabolism of deoxynivalenol administered to rats. 1989 Xenobiotica pmid:2756716
Li YH et al. [The inhibitory effect of deoxynivalenol on TAP-1 expression in human peripheral blood mononuclear cells in vitro]. 2005 Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi pmid:15766417
Zhu FX et al. [Enhancing effect of deoxynivalenol-mediated GRP78 down-regulation on heavy chain secretion and bioactivity of two-chain FVIII gene co-transfected cells]. 2011 Yao Xue Xue Bao pmid:22375418
Blaas W et al. [Determination of deoxynivalenol and nivalenol in cereals at the microgram/kilogram range]. 1984 Z Lebensm Unters Forsch pmid:6485556
Mulders EJ and van Impelen-Peek HA Gas chromatographic determination of deoxynivalenol in cereals. 1986 Z Lebensm Unters Forsch pmid:3811598
Steinmeyer S et al. [Gas chromatographic study of deoxynivalenol and nivalenol in cereals following derivatization with heptafluorobutyrates]. 1985 Z Lebensm Unters Forsch pmid:4050128
Baldwin NC et al. Biosynthesis of trichothecene mycotoxins in Fusarium culmorum cultures. 1985 Jul-Aug Z. Naturforsch., C, Biosci. pmid:4050026
Bergsjø B et al. Effects of diets with graded levels of deoxynivalenol on performance in growing pigs. 1992 Zentralbl Veterinarmed A pmid:1492508
Marpegan MR et al. Feed refusal of pigs caused by Fusarium mycotoxins in Argentina. 1988 Zentralbl Veterinarmed A pmid:3142186
Rizzo AF et al. Protective effect of antioxidants against free radical-mediated lipid peroxidation induced by DON or T-2 toxin. 1994 Zentralbl Veterinarmed A pmid:8091893
Overnes G et al. Effects of diets with graded levels of naturally deoxynivalenol-contaminated oats on immune response in growing pigs. 1997 Zentralbl Veterinarmed A pmid:9465774
Ali-Vehmas T et al. Measurement of antibacterial activities of T-2 toxin, deoxynivalenol, ochratoxin A, aflatoxin B1 and fumonisin B1 using microtitration tray-based turbidimetric techniques. 1998 Zentralbl Veterinarmed A pmid:9838857
Usleber E et al. Studies on the application of enzyme immunoassays for the Fusarium mycotoxins deoxynivalenol, 3-acetyldeoxynivalenol, and zearalenone. 1992 Zentralblatt Veterinarmedizin Reihe B pmid:1462727
Lu G et al. [Studies on deoxynivalenol contamination in grain and its products in Anhui Province]. 1994 Zhonghua Yu Fang Yi Xue Za Zhi pmid:8082456
Hou HF et al. [The cytotoxic effect and injury mechanism of deoxynivalenol on articular chondrocytes in human embryo]. 2011 Zhonghua Yu Fang Yi Xue Za Zhi pmid:22041568
Peng SQ and Yang JS [Effect of deoxynivalenol on action potentials of cultured cardiomyocytes and the protective effects of selenium]. 2003 Zhonghua Yu Fang Yi Xue Za Zhi pmid:14703497
Li FQ et al. [Natural occurrence of masked deoxynivalenol and multi-mycotoxins in cereals from China harvested in 2007 and 2008]. 2011 Zhonghua Yu Fang Yi Xue Za Zhi pmid:21418821
Guo HW [Gas chromatography with electron capture detector for determining DON and NIV in scabby wheat]. 1989 Zhonghua Yu Fang Yi Xue Za Zhi pmid:2625066
Wang W et al. [Probabilistic assessment of dietary exposure to both deoxynivalenol and zearalenone from cereal-based products in Chinese populations]. 2015 Zhonghua Yu Fang Yi Xue Za Zhi pmid:26268865
Zhou BJ et al. [Effects of vitamin C on apoptosis and proliferation inhibition of human peripheral blood mononuclear cells induced by deoxynivalenol in vitro]. 2006 Zhonghua Yu Fang Yi Xue Za Zhi pmid:17166419
Zhou BJ et al. [Effects of vitamin C on the inhibition of human leucocyte antigen class I (HLA-I) expression of human peripheral blood mononuclear cells induced by deoxynivalenol in vitro]. 2006 Zhonghua Yu Fang Yi Xue Za Zhi pmid:17166420
Huang XH et al. [Carcinogenic effects of sterigmatocystin and deoxynivalenol in NIH mice]. 2004 Zhonghua Zhong Liu Za Zhi pmid:15733384