Vomitoxin is a lipid of Prenol Lipids (PR) class. Vomitoxin is associated with abnormalities such as Infection and Gastroenteritis. The involved functions are known as mRNA Expression, Inflammation, Transcription, Genetic, Protein Biosynthesis and Adverse effects. Vomitoxin often locates in Lymphoid Tissue, Immune system, Bone Marrow and Plasma membrane. The associated genes with Vomitoxin are IMPACT gene, HIST1H1C gene and RBM39 gene. The related experimental models are Mouse Model.
To understand associated biological information of Vomitoxin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Vomitoxin is suspected in Infection, Gastroenteritis and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Vomitoxin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Dietary fish oil suppresses experimental immunoglobulin a nephropathy in mice.' (Pestka JJ et al., 2002).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Ok HE et al. | Determination of deoxynivalenol in cereal-based foods and estimation of dietary exposure. | 2009 | J. Toxicol. Environ. Health Part A | pmid:20077214 |
Biro D et al. | Occurrence of microscopic fungi and mycotoxins in conserved high moisture corn from Slovakia. | 2009 | Ann Agric Environ Med | pmid:20047255 |
Costa S et al. | In vitro evaluation of the chemoprotective action mechanisms of leontopodic acid against aflatoxin B1 and deoxynivalenol-induced cell damage. | 2009 | J Appl Toxicol | pmid:18636399 |
Prandini A et al. | Review of predictive models for Fusarium head blight and related mycotoxin contamination in wheat. | 2009 | Food Chem. Toxicol. | pmid:18634842 |
Türker L and Gümüş S | A theoretical study on vomitoxin and its tautomers. | 2009 | J. Hazard. Mater. | pmid:18657904 |
Placha I et al. | Effects of excessive selenium supplementation to diet contaminated with deoxynivalenol on blood phagocytic activity and antioxidative status of broilers. | 2009 | J Anim Physiol Anim Nutr (Berl) | pmid:18700846 |
Shi Y and Pestka JJ | Mechanisms for suppression of interleukin-6 expression in peritoneal macrophages from docosahexaenoic acid-fed mice. | 2009 | J. Nutr. Biochem. | pmid:18602807 |
Liu Y et al. | Feasibility of FT–Raman spectroscopy for rapid screening for DON toxin in ground wheat and barley. | 2009 | Food Addit Contam Part A Chem Anal Control Expo Risk Assess | pmid:21462584 |
Cowger C et al. | Post-anthesis moisture increased Fusarium head blight and deoxynivalenol levels in North Carolina winter wheat. | 2009 | Phytopathology | pmid:19271972 |
Yaguchi A et al. | Isolation and identification of precocenes and piperitone from essential oils as specific inhibitors of trichothecene production by Fusarium graminearum. | 2009 | J. Agric. Food Chem. | pmid:19191669 |
Pinton P et al. | The food contaminant deoxynivalenol, decreases intestinal barrier permeability and reduces claudin expression. | 2009 | Toxicol. Appl. Pharmacol. | pmid:19289138 |
Gutzwiller A et al. | Effects of a diet containing fusarium toxins on the fertility of gilts and on bulbourethral gland weight in barrows. | 2009 | Arch Anim Nutr | pmid:19271548 |
He J et al. | Concurrent selection for microbial suppression of Fusarium graminearum, Fusarium head blight and deoxynivalenol in wheat. | 2009 | J. Appl. Microbiol. | pmid:19298518 |
Levkut M et al. | Leukocytic responses of broilers following dietary contamination with deoxynivalenol and/or treatment by dietary selenium supplementation. | 2009 | Br. Poult. Sci. | pmid:19373718 |
Nielsen C et al. | Potential of deoxynivalenol to induce transcription factors in human hepatoma cells. | 2009 | Mol Nutr Food Res | pmid:19360757 |
Waché YJ et al. | Impact of deoxynivalenol on the intestinal microflora of pigs. | 2009 | Int J Mol Sci | pmid:19333431 |
Shi Y et al. | Role of GRP78/BiP degradation and ER stress in deoxynivalenol-induced interleukin-6 upregulation in the macrophage. | 2009 | Toxicol. Sci. | pmid:19336499 |
Kostelanska M et al. | Occurrence of deoxynivalenol and its major conjugate, deoxynivalenol-3-glucoside, in beer and some brewing intermediates. | 2009 | J. Agric. Food Chem. | pmid:19301815 |
Lee J et al. | Genetic diversity and fitness of Fusarium graminearum populations from rice in Korea. | 2009 | Appl. Environ. Microbiol. | pmid:19304830 |
Liu J et al. | [Effects of deoxynivalenol on apoptosis of human gastric carcinoma cell line SGC-7901, BGC-823 in vitro]. | 2009 | Wei Sheng Yan Jiu | pmid:19689068 |
Tanaka H et al. | Determination of nivalenol and deoxynivalenol by liquid chromatography/atmospheric pressure photoionization mass spectrometry. | 2009 | Rapid Commun. Mass Spectrom. | pmid:19714706 |
Muri SD et al. | Comparison of human health risks resulting from exposure to fungicides and mycotoxins via food. | 2009 | Food Chem. Toxicol. | pmid:19345717 |
Döll S et al. | Deoxynivalenol-induced cytotoxicity, cytokines and related genes in unstimulated or lipopolysaccharide stimulated primary porcine macrophages. | 2009 | Toxicol. Lett. | pmid:19027837 |
Zhang YJ et al. | Quantification of Fusarium graminearum in harvested grain by real-time polymerase chain reaction to assess efficacies of fungicides on fusarium head blight, deoxynivalenol contamination, and yield of winter wheat. | 2009 | Phytopathology | pmid:19055440 |
Tangni EK et al. | Mycotoxin analyses in some home produced eggs in Belgium reveal small contribution to the total daily intake. | 2009 | Sci. Total Environ. | pmid:19041117 |
Roigé MB et al. | Mycobiota and mycotoxins in fermented feed, wheat grains and corn grains in Southeastern Buenos Aires Province, Argentina. | 2009 | Rev Iberoam Micol | pmid:19766518 |
Caloni F et al. | Effects of a trichothecene, T-2 toxin, on proliferation and steroid production by porcine granulosa cells. | 2009 | Toxicon | pmid:19463844 |
Zhang X et al. | The role of oxidative stress in deoxynivalenol-induced DNA damage in HepG2 cells. | 2009 | Toxicon | pmid:19486909 |
Zielonka Å et al. | Influence of low doses of deoxynivalenol on histopathology of selected organs of pigs. | 2009 | Pol J Vet Sci | pmid:19459445 |
Gardiner DM et al. | Low pH regulates the production of deoxynivalenol by Fusarium graminearum. | 2009 | Microbiology (Reading, Engl.) | pmid:19497949 |
Döll S et al. | Interactions of deoxynivalenol and lipopolysaccharides on cytotoxicity protein synthesis and metabolism of DON in porcine hepatocytes and Kupffer cell enriched hepatocyte cultures. | 2009 | Toxicol. Lett. | pmid:19477247 |
Ferrari L et al. | Cellular immune response and immunotoxicity induced by DON (deoxynivalenol) in piglets. | 2009 | Vet. Res. Commun. | pmid:19578957 |
Waché YJ et al. | The mycotoxin deoxynivalenol inhibits the cell surface expression of activation markers in human macrophages. | 2009 | Toxicology | pmid:19549553 |
Choi HJ et al. | HuR/ELAVL1 RNA binding protein modulates interleukin-8 induction by muco-active ribotoxin deoxynivalenol. | 2009 | Toxicol. Appl. Pharmacol. | pmid:19591856 |
Vendl O et al. | Simultaneous determination of deoxynivalenol, zearalenone, and their major masked metabolites in cereal-based food by LC-MS-MS. | 2009 | Anal Bioanal Chem | pmid:19572123 |
Soubra L et al. | Occurrence of total aflatoxins, ochratoxin A and deoxynivalenol in foodstuffs available on the Lebanese market and their impact on dietary exposure of children and teenagers in Beirut. | 2009 | Food Addit Contam Part A Chem Anal Control Expo Risk Assess | pmid:19680889 |
Brenn-Struckhofova Z et al. | Co-isolation of deoxynivalenol and zearalenone with sol-gel immunoaffinity columns for their determination in wheat and wheat products. | 2009 | J Chromatogr A | pmid:19573873 |
RÃos G et al. | Impact of durum wheat milling on deoxynivalenol distribution in the outcoming fractions. | 2009 | Food Addit Contam Part A Chem Anal Control Expo Risk Assess | pmid:19680923 |
Berthiller F et al. | Occurrence of deoxynivalenol and its 3-beta-D-glucoside in wheat and maize. | 2009 | Food Addit Contam Part A Chem Anal Control Expo Risk Assess | pmid:19680925 |
Rivas Casado M et al. | Geostatistical analysis of the spatial distribution of mycotoxin concentration in bulk cereals. | 2009 | Food Addit Contam Part A Chem Anal Control Expo Risk Assess | pmid:19680962 |
De Girolamo A et al. | Rapid and non-invasive analysis of deoxynivalenol in durum and common wheat by Fourier-Transform Near Infrared (FT-NIR) spectroscopy. | 2009 | Food Addit Contam Part A Chem Anal Control Expo Risk Assess | pmid:19680966 |
Edwards SG | Fusarium mycotoxin content of UK organic and conventional oats. | 2009 | Food Addit Contam Part A Chem Anal Control Expo Risk Assess | pmid:19680981 |
Wu X et al. | Deoxynivalenol suppresses circulating and splenic leukocyte subpopulations in BALB/c mice: dose response, time course and sex differences. | 2009 | Food Addit Contam Part A Chem Anal Control Expo Risk Assess | pmid:19680982 |
Amuzie CJ et al. | Induction of suppressors of cytokine signaling by the trichothecene deoxynivalenol in the mouse. | 2009 | Toxicol. Sci. | pmid:19625342 |
Bensassi F et al. | Pathway of deoxynivalenol-induced apoptosis in human colon carcinoma cells. | 2009 | Toxicology | pmid:19664677 |
Turner PC et al. | A comparison of 24 h urinary deoxynivalenol with recent v. average cereal consumption for UK adults. | 2009 | Br. J. Nutr. | pmid:19653921 |
Döll S et al. | Interactions of deoxynivalenol and lipopolysaccharides on cytokine excretion and mRNA expression in porcine hepatocytes and Kupffer cell enriched hepatocyte cultures. | 2009 | Toxicol. Lett. | pmid:19607891 |
Scudamore KA and Patel S | Occurrence of Fusarium mycotoxins in maize imported into the UK, 2004-2007. | 2009 | Food Addit Contam Part A Chem Anal Control Expo Risk Assess | pmid:19680910 |
Kolf-Clauw M et al. | Development of a pig jejunal explant culture for studying the gastrointestinal toxicity of the mycotoxin deoxynivalenol: histopathological analysis. | 2009 | Toxicol In Vitro | pmid:19607908 |
Ansari KI et al. | Overexpression of human histone methylase MLL1 upon exposure to a food contaminant mycotoxin, deoxynivalenol. | 2009 | FEBS J. | pmid:19438726 |
Yu C et al. | [Study advance on formation, transformation and detection of masked deoxynivalenol]. | 2009 | Wei Sheng Yan Jiu | pmid:19408673 |
Vasatkova A et al. | Changes in metallothionein level in rat hepatic tissue after administration of natural mouldy wheat. | 2009 | Int J Mol Sci | pmid:19399242 |
Marzocco S et al. | Pro-apoptotic effects of nivalenol and deoxynivalenol trichothecenes in J774A.1 murine macrophages. | 2009 | Toxicol. Lett. | pmid:19410639 |
Chen X et al. | Fusarium graminearum exploits ethylene signalling to colonize dicotyledonous and monocotyledonous plants. | 2009 | New Phytol. | pmid:19383094 |
Gardiner DM et al. | Novel genes of Fusarium graminearum that negatively regulate deoxynivalenol production and virulence. | 2009 | Mol. Plant Microbe Interact. | pmid:19888824 |
Franz E et al. | Prediction of deoxynivalenol content in Dutch winter wheat. | 2009 | J. Food Prot. | pmid:19833041 |
Jakovac-Strajn B et al. | Effects of a deoxynivalenol-contaminated diet on the reproductive performance and immunoglobulin concentrations in pigs. | 2009 | Vet. Rec. | pmid:20008344 |
Wang K et al. | A novel and sensitive method for the detection of deoxynivalenol in food by time-resolved fluoroimmunoassay. | 2009 | Toxicol. Mech. Methods | pmid:19874133 |
Neumann G et al. | Determination of deoxynivalenol in soft wheat by immunoaffinity column cleanup and LC-UV detection: interlaboratory study. | 2009 Jan-Feb | J AOAC Int | pmid:19382577 |
Vandenbroucke V et al. | The mycotoxin deoxynivalenol promotes uptake of Salmonella Typhimurium in porcine macrophages, associated with ERK1/2 induced cytoskeleton reorganization. | 2009 Nov-Dec | Vet. Res. | pmid:19674540 |
Bergamini E et al. | Fate of Fusarium mycotoxins in the cereal product supply chain: the deoxynivalenol (DON) case within industrial bread-making technology. | 2010 | Food Addit Contam Part A Chem Anal Control Expo Risk Assess | pmid:20455161 |
Mikami O et al. | Induction of apoptotic lesions in liver and lymphoid tissues and modulation of cytokine mRNA expression by acute exposure to deoxynivalenol in piglets. | 2010 | J. Vet. Sci. | pmid:20458150 |
Romanazzo D et al. | Development of a recombinant Fab-fragment based electrochemical immunosensor for deoxynivalenol detection in food samples. | 2010 | Biosens Bioelectron | pmid:20466534 |
Awad WA et al. | Decontamination and detoxification strategies for the Fusarium mycotoxin deoxynivalenol in animal feed and the effectiveness of microbial biodegradation. | 2010 | Food Addit Contam Part A Chem Anal Control Expo Risk Assess | pmid:20234966 |
Yoshida M and Nakajima T | Deoxynivalenol and nivalenol accumulation in wheat infected with Fusarium graminearum during grain development. | 2010 | Phytopathology | pmid:20626280 |
Kadota T et al. | Rapid detection of nivalenol and deoxynivalenol in wheat using surface plasmon resonance immunoassay. | 2010 | Anal. Chim. Acta | pmid:20599032 |
Van De Walle J et al. | Physio-pathological parameters affect the activation of inflammatory pathways by deoxynivalenol in Caco-2 cells. | 2010 | Toxicol In Vitro | pmid:20633634 |
Audenaert K et al. | Hydrogen peroxide induced by the fungicide prothioconazole triggers deoxynivalenol (DON) production by Fusarium graminearum. | 2010 | BMC Microbiol. | pmid:20398299 |
Gardiner SA et al. | Transcriptome analysis of the barley-deoxynivalenol interaction: evidence for a role of glutathione in deoxynivalenol detoxification. | 2010 | Mol. Plant Microbe Interact. | pmid:20521958 |
Wada K et al. | Effects of mycotoxins on chemiluminescent response and cytokine mRNA expression of bovine neutrophils. | 2010 | J. Vet. Med. Sci. | pmid:20622479 |
Schweiger W et al. | Validation of a candidate deoxynivalenol-inactivating UDP-glucosyltransferase from barley by heterologous expression in yeast. | 2010 | Mol. Plant Microbe Interact. | pmid:20521959 |
Malovrh T and Jakovac-Strajn B | Feed contaminated with Fusarium toxins alter lymphocyte proliferation and apoptosis in primiparous sows during the perinatal period. | 2010 | Food Chem. Toxicol. | pmid:20654678 |
Schoevers EJ et al. | Porcine oocytes are most vulnerable to the mycotoxin deoxynivalenol during formation of the meiotic spindle. | 2010 | Theriogenology | pmid:20570324 |
Vendl O et al. | Occurrence of free and conjugated Fusarium mycotoxins in cereal-based food. | 2010 | Food Addit Contam Part A Chem Anal Control Expo Risk Assess | pmid:20496251 |
Cunha SC and Fernandes JO | Development and validation of a method based on a QuEChERS procedure and heart-cutting GC-MS for determination of five mycotoxins in cereal products. | 2010 | J Sep Sci | pmid:20155747 |
KÅ‚osowski G et al. | The influence of raw material contamination with mycotoxins on alcoholic fermentation indicators. | 2010 | Bioresour. Technol. | pmid:20074946 |
Magan N et al. | Environmental factors and interactions with mycobiota of grain and grapes: effects on growth, deoxynivalenol and ochratoxin production by Fusarium culmorum and Aspergillus carbonarius. | 2010 | Toxins (Basel) | pmid:22069589 |
Baldwin TK et al. | A partial chromosomal deletion caused by random plasmid integration resulted in a reduced virulence phenotype in Fusarium graminearum. | 2010 | Mol. Plant Microbe Interact. | pmid:20615118 |
Pestka JJ | Deoxynivalenol-induced proinflammatory gene expression: mechanisms and pathological sequelae. | 2010 | Toxins (Basel) | pmid:22069639 |
Meneely J et al. | Rapid surface plasmon resonance immunoassay for the determination of deoxynivalenol in wheat, wheat products, and maize-based baby food. | 2010 | J. Agric. Food Chem. | pmid:23654230 |
Pestka JJ | Deoxynivalenol: mechanisms of action, human exposure, and toxicological relevance. | 2010 | Arch. Toxicol. | pmid:20798930 |
Casteel M et al. | Impact of DUSP1 on the apoptotic potential of deoxynivalenol in the epithelial cell line HepG2. | 2010 | Toxicol. Lett. | pmid:20708668 |
Beyer M et al. | Estimating deoxynivalenol contents of wheat samples containing different levels of Fusarium-damaged kernels by diffuse reflectance spectrometry and partial least square regression. | 2010 | Int. J. Food Microbiol. | pmid:20678823 |
Thammawong M et al. | Distribution of deoxynivalenol and nivalenol in milling fractions from fusarium-infected Japanese wheat cultivars. | 2010 | J. Food Prot. | pmid:21067669 |
Tangni EK et al. | Cross-reactivity of antibodies in some commercial deoxynivalenol test kits against some fusariotoxins. | 2010 | J. Agric. Food Chem. | pmid:21087038 |
Dänicke S et al. | Investigations on the kinetics of the concentration of deoxynivalenol (DON) and on spoilage by moulds and yeasts of wheat grain preserved with sodium metabisulfite (Na2S2O5, SBS) and propionic acid at various moisture contents. | 2010 | Arch Anim Nutr | pmid:20578648 |
Dänicke S et al. | Effects of oral exposure of pigs to deoxynivalenol (DON) sulfonate (DONS) as the non-toxic derivative of DON on tissue residues of DON and de-epoxy-DON and on DONS blood levels. | 2010 | Food Addit Contam Part A Chem Anal Control Expo Risk Assess | pmid:20677033 |
Puri KD and Zhong S | The 3ADON population of Fusarium graminearum found in North Dakota is more aggressive and produces a higher level of DON than the prevalent 15ADON population in spring wheat. | 2010 | Phytopathology | pmid:20839936 |
Pinton P et al. | Deoxynivalenol impairs porcine intestinal barrier function and decreases the protein expression of claudin-4 through a mitogen-activated protein kinase-dependent mechanism. | 2010 | J. Nutr. | pmid:20861219 |
Voss KA and Snook ME | Stability of the mycotoxin deoxynivalenol (DON) during the production of flour-based foods and wheat flake cereal. | 2010 | Food Addit Contam Part A Chem Anal Control Expo Risk Assess | pmid:20936557 |
He CH et al. | The individual and combined effects of deoxynivalenol and aflatoxin Bâ‚on primary hepatocytes of Cyprinus carpio. | 2010 | Int J Mol Sci | pmid:21152299 |
Jin PG et al. | Simultaneous determination of 10 mycotoxins in grain by ultra-high-performance liquid chromatography-tandem mass spectrometry using ¹³Câ‚â‚…-deoxynivalenol as internal standard. | 2010 | Food Addit Contam Part A Chem Anal Control Expo Risk Assess | pmid:20938852 |
Klinglmayr C et al. | Determination of deoxynivalenol in organic and conventional food and feed by sol-gel immunoaffinity chromatography and HPLC-UV detection. | 2010 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:19736050 |
Luongo D et al. | Trichothecenes NIV and DON modulate the maturation of murine dendritic cells. | 2010 | Toxicon | pmid:19635492 |
Poapolathep A et al. | The effect of naringenin on the fate and disposition of deoxynivalenol in piglets. | 2010 | J. Vet. Med. Sci. | pmid:20467205 |
Min WK et al. | Production and characterization of monoclonal antibody and its recombinant single chain variable fragment specific for a food-born mycotoxin, fumonisin B1. | 2010 | Bioprocess Biosyst Eng | pmid:19597742 |
Sugiyama K et al. | Deoxynivalenol and nivalenol inhibit lipopolysaccharide-induced nitric oxide production by mouse macrophage cells. | 2010 | Toxicol. Lett. | pmid:19857559 |
Amuzie CJ and Pestka JJ | Suppression of insulin-like growth factor acid-labile subunit expression--a novel mechanism for deoxynivalenol-induced growth retardation. | 2010 | Toxicol. Sci. | pmid:19805407 |
Demeke T et al. | Development of a specific TaqMan real-time PCR assay for quantification of Fusarium graminearum clade 7 and comparison of fungal biomass determined by PCR with deoxynivalenol content in wheat and barley. | 2010 | Int. J. Food Microbiol. | pmid:20483187 |
Lehoczki-Krsjak S et al. | Prevention of Fusarium mycotoxin contamination by breeding and fungicide application to wheat. | 2010 | Food Addit Contam Part A Chem Anal Control Expo Risk Assess | pmid:20455158 |