Vomitoxin is a lipid of Prenol Lipids (PR) class. Vomitoxin is associated with abnormalities such as Infection and Gastroenteritis. The involved functions are known as mRNA Expression, Inflammation, Transcription, Genetic, Protein Biosynthesis and Adverse effects. Vomitoxin often locates in Lymphoid Tissue, Immune system, Bone Marrow and Plasma membrane. The associated genes with Vomitoxin are IMPACT gene, HIST1H1C gene and RBM39 gene. The related experimental models are Mouse Model.
To understand associated biological information of Vomitoxin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Vomitoxin is suspected in Infection, Gastroenteritis and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Vomitoxin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Dietary fish oil suppresses experimental immunoglobulin a nephropathy in mice.' (Pestka JJ et al., 2002).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Abia WA et al. | Bio-monitoring of mycotoxin exposure in Cameroon using a urinary multi-biomarker approach. | 2013 | Food Chem. Toxicol. | pmid:24128729 |
Blandino M et al. | Nutritional and technological quality of bread enriched with an intermediated pearled wheat fraction. | 2013 | Food Chem | pmid:23870994 |
Zheng Z et al. | Involvement of the anucleate primary sterigmata protein FgApsB in vegetative differentiation, asexual development, nuclear migration, and virulence in Fusarium graminearum. | 2013 | FEMS Microbiol. Lett. | pmid:24117691 |
Dänicke S et al. | Ascaridia galli infection affects pullets differently when feed is contaminated with the Fusarium toxin deoxynivalenol (DON). | 2013 | Vet. Parasitol. | pmid:24113465 |
Fan J et al. | Characterization of the sterol 14α-demethylases of Fusarium graminearum identifies a novel genus-specific CYP51 function. | 2013 | New Phytol. | pmid:23442154 |
Pasquali M et al. | FcStuA from Fusarium culmorum controls wheat foot and root rot in a toxin dispensable manner. | 2013 | PLoS ONE | pmid:23451228 |
Lee HM et al. | Development of a monoclonal antibody against deoxynivalenol for magnetic nanoparticle-based extraction and an enzyme-linked immunosorbent assay. | 2013 | J. Vet. Sci. | pmid:23388439 |
Xiao H et al. | Effects of composite antimicrobial peptides in weanling piglets challenged with deoxynivalenol: I. Growth performance, immune function, and antioxidation capacity. | 2013 | J. Anim. Sci. | pmid:23965387 |
Xiao H et al. | Effects of composite antimicrobial peptides in weanling piglets challenged with deoxynivalenol: II. Intestinal morphology and function. | 2013 | J. Anim. Sci. | pmid:23965392 |
MartÃnez G et al. | Penetration of fosfomycin into IPEC-J2 cells in the presence or absence of deoxynivalenol. | 2013 | PLoS ONE | pmid:24040387 |
Ghareeb K et al. | Effects of feed contaminant deoxynivalenol on plasma cytokines and mRNA expression of immune genes in the intestine of broiler chickens. | 2013 | PLoS ONE | pmid:23977054 |
Wu W et al. | Comparison of emetic potencies of the 8-ketotrichothecenes deoxynivalenol, 15-acetyldeoxynivalenol, 3-acetyldeoxynivalenol, fusarenon X, and nivalenol. | 2013 | Toxicol. Sci. | pmid:22997060 |
Gauthier T et al. | Deoxynivalenol impairs the immune functions of neutrophils. | 2013 | Mol Nutr Food Res | pmid:23427020 |
Yunus AW and Böhm J | Serum cation profile of broilers at various stages of exposure to deoxynivalenol. | 2013 | Mycotoxin Res | pmid:23430398 |
Yoshinari T et al. | Inter-laboratory study of an LC-MS/MS method for simultaneous determination of deoxynivalenol and its acetylated derivatives, 3-acetyl-deoxynivalenol and 15-acetyl-deoxynivalenol in wheat. | 2013 | Shokuhin Eiseigaku Zasshi | pmid:23470877 |
Wu W et al. | Peptide YY3-36 and 5-hydroxytryptamine mediate emesis induction by trichothecene deoxynivalenol (vomitoxin). | 2013 | Toxicol. Sci. | pmid:23457120 |
Choi BK et al. | Effects of oral deoxynivalenol exposure on immune-related parameters in lymphoid organs and serum of mice vaccinated with porcine parvovirus vaccine. | 2013 | Mycotoxin Res | pmid:23436220 |
Escobar J et al. | Occurrence and exposure assessment of Fusarium mycotoxins in maize germ, refined corn oil and margarine. | 2013 | Food Chem. Toxicol. | pmid:24056029 |
Cowger C and Arellano C | Fusarium graminearum infection and deoxynivalenol concentrations during development of wheat spikes. | 2013 | Phytopathology | pmid:23252971 |
Schmeits PC et al. | Assessment of the usefulness of the murine cytotoxic T cell line CTLL-2 for immunotoxicity screening by transcriptomics. | 2013 | Toxicol. Lett. | pmid:23253260 |
Li Y et al. | Study of the interaction of deoxynivalenol with human serum albumin by spectroscopic technique and molecular modelling. | 2013 | Food Addit Contam Part A Chem Anal Control Expo Risk Assess | pmid:23205852 |
Hiraoka H et al. | Modified use of a commercial ELISA kit for deoxynivalenol determination in rice and corn silage. | 2013 | Mycotoxin Res | pmid:23275133 |
Ito M et al. | Bacterial cytochrome P450 system catabolizing the Fusarium toxin deoxynivalenol. | 2013 | Appl. Environ. Microbiol. | pmid:23275503 |
Sifuentes dos Santos J et al. | Natural occurrence of deoxynivalenol in wheat from Paraná State, Brazil and estimated daily intake by wheat products. | 2013 | Food Chem | pmid:23265460 |
Pan X et al. | Global protein phosphorylation dynamics during deoxynivalenol-induced ribotoxic stress response in the macrophage. | 2013 | Toxicol. Appl. Pharmacol. | pmid:23352502 |
Cano PM et al. | Deoxynivalenol as a new factor in the persistence of intestinal inflammatory diseases: an emerging hypothesis through possible modulation of Th17-mediated response. | 2013 | PLoS ONE | pmid:23326479 |
Krout-Greenberg ND et al. | Preliminary study to assess mycotoxin concentrations in whole corn in the California feed supply. | 2013 | J. Dairy Sci. | pmid:23462178 |
Flannery BM et al. | Deoxynivalenol-induced weight loss in the diet-induced obese mouse is reversible and PKR-independent. | 2013 | Toxicol. Lett. | pmid:23707852 |
Linkmeyer A et al. | Assessment and introduction of quantitative resistance to Fusarium head blight in elite spring barley. | 2013 | Phytopathology | pmid:23777405 |
Sanders M et al. | Sampling of wheat dust and subsequent analysis of deoxynivalenol by LC-MS/MS. | 2013 | J. Agric. Food Chem. | pmid:23782015 |
Alassane-Kpembi I et al. | New insights into mycotoxin mixtures: the toxicity of low doses of Type B trichothecenes on intestinal epithelial cells is synergistic. | 2013 | Toxicol. Appl. Pharmacol. | pmid:23735874 |
Schweiger W et al. | Transcriptomic characterization of two major Fusarium resistance quantitative trait loci (QTLs), Fhb1 and Qfhs.ifa-5A, identifies novel candidate genes. | 2013 | Mol. Plant Pathol. | pmid:23738863 |
Winter M et al. | Mechanisms regulating grain contamination with trichothecenes translocated from the stem base of wheat (Triticum aestivum) infected with Fusarium culmorum. | 2013 | Phytopathology | pmid:23758328 |
Ngampongsa S et al. | Toxic effects of T-2 toxin and deoxynivalenol on the mitochondrial electron transport system of cardiomyocytes in rats. | 2013 | J Toxicol Sci | pmid:23719927 |
He K et al. | Modulation of inflammatory gene expression by the ribotoxin deoxynivalenol involves coordinate regulation of the transcriptome and translatome. | 2013 | Toxicol. Sci. | pmid:22968694 |
Sliková S et al. | Occurrence of deoxynivalenol in wheat in Slovakia during 2010 and 2011. | 2013 | Toxins (Basel) | pmid:23917334 |
Albert AL et al. | QuickTox Kit for QuickScan DON (Vomitoxin). | 2013 Sep-Oct | J AOAC Int | pmid:24282939 |
Liu N et al. | The transcription cofactor FgSwi6 plays a role in growth and development, carbendazim sensitivity, cellulose utilization, lithium tolerance, deoxynivalenol production and virulence in the filamentous fungus Fusarium graminearum. | 2013 Sep-Oct | Fungal Genet. Biol. | pmid:23994322 |
Ji F et al. | Natural occurrence of deoxynivalenol and zearalenone in wheat from Jiangsu province, China. | 2014 | Food Chem | pmid:24679796 |
Hubert J et al. | The effect of Tyrophagus putrescentiae on Fusarium poae transmission and fungal community in stored barley in a laboratory experiment. | 2014 | Insect Sci. | pmid:23955921 |
Choi HJ et al. | Postharvest strategies for deoxynivalenol and zearalenone reduction in stored adlay (Coix lachryma-jobi L.) grains. | 2014 | J. Food Prot. | pmid:24674439 |
Cortinovis C et al. | Effects of fumonisin B1 alone and combined with deoxynivalenol or zearalenone on porcine granulosa cell proliferation and steroid production. | 2014 | Theriogenology | pmid:24576714 |
van der Fels-Klerx HJ | Evaluation of performance of predictive models for deoxynivalenol in wheat. | 2014 | Risk Anal. | pmid:23901939 |
Mudili V et al. | Mould incidence and mycotoxin contamination in freshly harvested maize kernels originated from India. | 2014 | J. Sci. Food Agric. | pmid:24609945 |
Devreese M et al. | The effects of feed-borne Fusarium mycotoxins and glucomannan in turkey poults based on specific and non-specific parameters. | 2014 | Food Chem. Toxicol. | pmid:24200858 |
Dzuman Z et al. | Enzyme-linked immunosorbent assay in analysis of deoxynivalenol: investigation of the impact of sample matrix on results accuracy. | 2014 | Anal Bioanal Chem | pmid:24292429 |
Mishra S et al. | Influence of temperature and pH on the degradation of deoxynivalenol (DON) in aqueous medium: comparative cytotoxicity of DON and degraded product. | 2014 | Food Addit Contam Part A Chem Anal Control Expo Risk Assess | pmid:24261986 |
Tran ST and Smith TK | Conjugation of deoxynivalenol by Alternaria alternata (54028 NRRL), Rhizopus microsporus var. rhizopodiformis (54029 NRRL) and Aspergillus oryzae (5509 NRRL). | 2014 | Mycotoxin Res | pmid:24263850 |
Malbrán I et al. | Toxigenic capacity and trichothecene production by Fusarium graminearum isolates from Argentina and their relationship with aggressiveness and fungal expansion in the wheat spike. | 2014 | Phytopathology | pmid:24168045 |
Navara S and Smith KP | Using near-isogenic barley lines to validate deoxynivalenol (DON) QTL previously identified through association analysis. | 2014 | Theor. Appl. Genet. | pmid:24343199 |
Pan X et al. | Dynamic changes in ribosome-associated proteome and phosphoproteome during deoxynivalenol-induced translation inhibition and ribotoxic stress. | 2014 | Toxicol. Sci. | pmid:24284785 |
Sun LH et al. | Hepatotoxic effects of mycotoxin combinations in mice. | 2014 | Food Chem. Toxicol. | pmid:25445755 |
Cirlini M et al. | Durum wheat (Triticum Durum Desf.) lines show different abilities to form masked mycotoxins under greenhouse conditions. | 2014 | Toxins (Basel) | pmid:24368326 |
Yang W et al. | Deoxynivalenol induced oxidative stress and genotoxicity in human peripheral blood lymphocytes. | 2014 | Food Chem. Toxicol. | pmid:24355168 |
Mohamed MS et al. | Type 1 ribotoxin-curcin conjugated biogenic gold nanoparticles for a multimodal therapeutic approach towards brain cancer. | 2014 | Biochim. Biophys. Acta | pmid:24361614 |
Ghareeb K et al. | Insights on the host stress, fear and growth responses to the deoxynivalenol feed contaminant in broiler chickens. | 2014 | PLoS ONE | pmid:24498179 |
Denschlag C et al. | Real-time loop-mediated isothermal amplification (LAMP) assay for group specific detection of important trichothecene producing Fusarium species in wheat. | 2014 | Int. J. Food Microbiol. | pmid:24631635 |
Audenaert K et al. | Deoxynivalenol: a major player in the multifaceted response of Fusarium to its environment. | 2014 | Toxins (Basel) | pmid:24451843 |
Giménez I et al. | Effects of bread making and wheat germ addition on the natural deoxynivalenol content in bread. | 2014 | Toxins (Basel) | pmid:24451845 |
Shi C et al. | Biocontrol of Fusarium graminearum growth and deoxynivalenol production in wheat kernels with bacterial antagonists. | 2014 | Int J Environ Res Public Health | pmid:24441510 |
Yoshinari T et al. | Structural determination of a nivalenol glucoside and development of an analytical method for the simultaneous determination of nivalenol and deoxynivalenol, and their glucosides, in wheat. | 2014 | J. Agric. Food Chem. | pmid:24433151 |
Fruhmann P et al. | Stereoselective Luche reduction of deoxynivalenol and three of its acetylated derivatives at C8. | 2014 | Toxins (Basel) | pmid:24434906 |
Jin F et al. | Fusarium-damaged kernels and deoxynivalenol in Fusarium-infected U.S. winter wheat. | 2014 | Phytopathology | pmid:24400658 |
Schmeits PC et al. | DON shares a similar mode of action as the ribotoxic stress inducer anisomycin while TBTO shares ER stress patterns with the ER stress inducer thapsigargin based on comparative gene expression profiling in Jurkat T cells. | 2014 | Toxicol. Lett. | pmid:24247028 |
Ansari KI et al. | Light influences how the fungal toxin deoxynivalenol affects plant cell death and defense responses. | 2014 | Toxins (Basel) | pmid:24561479 |
Pietsch C et al. | Organ damage and hepatic lipid accumulation in carp (Cyprinus carpio L.) after feed-borne exposure to the mycotoxin, deoxynivalenol (DON). | 2014 | Toxins (Basel) | pmid:24566729 |
Akbari P et al. | Deoxynivalenol: a trigger for intestinal integrity breakdown. | 2014 | FASEB J. | pmid:24568843 |
Wu W et al. | Role of cholecystokinin in anorexia induction following oral exposure to the 8-ketotrichothecenes deoxynivalenol, 15-acetyldeoxynivalenol, 3-acetyldeoxynivalenol, fusarenon X, and nivalenol. | 2014 | Toxicol. Sci. | pmid:24385417 |
Savard C et al. | In vitro effect of deoxynivalenol (DON) mycotoxin on porcine reproductive and respiratory syndrome virus replication. | 2014 | Food Chem. Toxicol. | pmid:24394488 |
Zhao Y et al. | Antagonistic action of Bacillus subtilis strain SG6 on Fusarium graminearum. | 2014 | PLoS ONE | pmid:24651513 |
Li D et al. | Evaluation of deoxynivalenol-induced toxic effects on DF-1 cells in vitro: cell-cycle arrest, oxidative stress, and apoptosis. | 2014 | Environ. Toxicol. Pharmacol. | pmid:24322622 |
Jajić I et al. | Incidence of deoxynivalenol in Serbian wheat and barley. | 2014 | J. Food Prot. | pmid:24780345 |
Sella L et al. | Fusarium graminearum Possesses Virulence Factors Common to Fusarium Head Blight of Wheat and Seedling Rot of Soybean but Differing in Their Impact on Disease Severity. | 2014 | Phytopathology | pmid:24779355 |
Zhou HR et al. | Direct activation of ribosome-associated double-stranded RNA-dependent protein kinase (PKR) by deoxynivalenol, anisomycin and ricin: a new model for ribotoxic stress response induction. | 2014 | Toxins (Basel) | pmid:25521494 |
Wu M et al. | An NMR-based metabolomic approach to investigate the effects of supplementation with glutamic acid in piglets challenged with deoxynivalenol. | 2014 | PLoS ONE | pmid:25502722 |
van der Fels-Klerx HJ et al. | A framework to determine the effectiveness of dietary exposure mitigation to chemical contaminants. | 2014 | Food Chem. Toxicol. | pmid:25445762 |
Wu W and Zhang H | Role of tumor necrosis factor-α and interleukin-1β in anorexia induction following oral exposure to the trichothecene deoxynivalenol (vomitoxin) in the mouse. | 2014 | J Toxicol Sci | pmid:25392278 |
De Girolamo A et al. | Rapid analysis of deoxynivalenol in durum wheat by FT-NIR spectroscopy. | 2014 | Toxins (Basel) | pmid:25384107 |
Devreese M et al. | Efficacy of active carbon towards the absorption of deoxynivalenol in pigs. | 2014 | Toxins (Basel) | pmid:25337799 |
Antonissen G et al. | The mycotoxin deoxynivalenol predisposes for the development of Clostridium perfringens-induced necrotic enteritis in broiler chickens. | 2014 | PLoS ONE | pmid:25268498 |
Wu W et al. | Comparison of anorectic and emetic potencies of deoxynivalenol (vomitoxin) to the plant metabolite deoxynivalenol-3-glucoside and synthetic deoxynivalenol derivatives EN139528 and EN139544. | 2014 | Toxicol. Sci. | pmid:25173790 |
Pinton P and Oswald IP | Effect of deoxynivalenol and other Type B trichothecenes on the intestine: a review. | 2014 | Toxins (Basel) | pmid:24859243 |
Matejova I et al. | The effect of mycotoxin deoxynivalenol on haematological and biochemical indicators and histopathological changes in rainbow trout (Oncorhynchus mykiss). | 2014 | Biomed Res Int | pmid:24729967 |
Moretti A et al. | Systemic growth of F. graminearum in wheat plants and related accumulation of deoxynivalenol. | 2014 | Toxins (Basel) | pmid:24727554 |
Yu F et al. | The TOR signaling pathway regulates vegetative development and virulence in Fusarium graminearum. | 2014 | New Phytol. | pmid:24684168 |
Bormann J et al. | The adenylyl cyclase plays a regulatory role in the morphogenetic switch from vegetative to pathogenic lifestyle of Fusarium graminearum on wheat. | 2014 | PLoS ONE | pmid:24603887 |
Aristimuño Ficoseco ME et al. | Antifungal and antimycotoxigenic metabolites in Anacardiaceae species from northwest Argentina: isolation, identification and potential for control of Fusarium species. | 2014 | J. Appl. Microbiol. | pmid:24428333 |
Patience JF et al. | Evaluation of two mycotoxin mitigation strategies in grow-finish swine diets containing corn dried distillers grains with solubles naturally contaminated with deoxynivalenol. | 2014 | J. Anim. Sci. | pmid:24398837 |
Weaver AC et al. | Protective effect of two yeast based feed additives on pigs chronically exposed to deoxynivalenol and zearalenone. | 2014 | Toxins (Basel) | pmid:25533517 |
Kim DH et al. | Incidence and levels of deoxynivalenol, fumonisins and zearalenone contaminants in animal feeds used in Korea in 2012. | 2014 | Toxins (Basel) | pmid:24366207 |
Qiu J and Shi J | Genetic relationships, carbendazim sensitivity and mycotoxin production of the Fusarium graminearum populations from maize, wheat and rice in eastern China. | 2014 | Toxins (Basel) | pmid:25093387 |
Waśkiewicz A et al. | Deoxynivalenol and oxidative stress indicators in winter wheat inoculated with Fusarium graminearum. | 2014 | Toxins (Basel) | pmid:24514944 |
Kosawang C et al. | Transcriptomic profiling to identify genes involved in Fusarium mycotoxin Deoxynivalenol and Zearalenone tolerance in the mycoparasitic fungus Clonostachys rosea. | 2014 | BMC Genomics | pmid:24450745 |
Yoshinari T et al. | Occurrence of four Fusarium mycotoxins, deoxynivalenol, zearalenone, T-2 toxin, and HT-2 toxin, in wheat, barley, and Japanese retail food. | 2014 | J. Food Prot. | pmid:25364928 |
Gerding J et al. | Determination of mycotoxin exposure in Germany using an LC-MS/MS multibiomarker approach. | 2014 | Mol Nutr Food Res | pmid:25243722 |
Kim KY et al. | Development of a simultaneous lateral flow strip test for the rapid and simple detection of deoxynivalenol and zearalenone. | 2014 | J. Food Sci. | pmid:25224778 |
Brezina U et al. | Development of a liquid chromatography tandem mass spectrometry method for the simultaneous determination of zearalenone, deoxynivalenol and their metabolites in pig serum. | 2014 | Mycotoxin Res | pmid:24925826 |
Bertuzzi T et al. | Co-occurrence of type A and B trichothecenes and zearalenone in wheat grown in northern Italy over the years 2009-2011. | 2014 | Food Addit Contam Part B Surveill | pmid:24848161 |
Song S et al. | Multiplex lateral flow immunoassay for mycotoxin determination. | 2014 | Anal. Chem. | pmid:24745689 |
Bensassi F et al. | In vitro investigation of toxicological interactions between the fusariotoxins deoxynivalenol and zearalenone. | 2014 | Toxicon | pmid:24680766 |