Vomitoxin
Vomitoxin is a lipid of Prenol Lipids (PR) class. Vomitoxin is associated with abnormalities such as Infection and Gastroenteritis. The involved functions are known as mRNA Expression, Inflammation, Transcription, Genetic, Protein Biosynthesis and Adverse effects. Vomitoxin often locates in Lymphoid Tissue, Immune system, Bone Marrow and Plasma membrane. The associated genes with Vomitoxin are IMPACT gene, HIST1H1C gene and RBM39 gene. The related experimental models are Mouse Model.
Cross Reference
Introduction
To understand associated biological information of Vomitoxin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Vomitoxin?
Vomitoxin is suspected in Infection, Gastroenteritis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Vomitoxin
PubChem Associated disorders and diseases
What pathways are associated with Vomitoxin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Vomitoxin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Vomitoxin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Vomitoxin?
There are no associated biomedical information in the current reference collection.
What genes are associated with Vomitoxin?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Vomitoxin?
Mouse Model
Mouse Model are used in the study 'Dietary fish oil suppresses experimental immunoglobulin a nephropathy in mice.' (Pestka JJ et al., 2002).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Vomitoxin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Urban M et al. | Arabidopsis is susceptible to the cereal ear blight fungal pathogens Fusarium graminearum and Fusarium culmorum. | 2002 | Plant J. | pmid:12492838 |
| Clifford LJ et al. | An improved method for the purification of the trichothecene deoxynivalenol (vomitoxin) from Fusarium graminearum culture. | 2003 | J. Agric. Food Chem. | pmid:12517120 |
| Wang H et al. | [Effects of deoxynivalenol on proliferation and tumor necrosis factor-alpha secretion of human peripheral blood mononuclear cells in vitro]. | 2000 | Wei Sheng Yan Jiu | pmid:12520964 |
| Perkowski J and Kaczmarek Z | Distribution of deoxynivalenol and 3-acetyldeoxynivalenol in naturally contaminated and Fusarium culmorum infected triticale samples. | 2002 | Nahrung | pmid:12577591 |
| Okubara PA et al. | Engineering deoxynivalenol metabolism in wheat through the expression of a fungal trichothecene acetyltransferase gene. | 2002 | Theor. Appl. Genet. | pmid:12582873 |
| Chung YJ et al. | Up-regulation of macrophage inflammatory protein-2 and complement 3A receptor by the trichothecenes deoxynivalenol and satratoxin G. | 2003 | Toxicology | pmid:12604170 |
| Zhou HR et al. | Rapid, sequential activation of mitogen-activated protein kinases and transcription factors precedes proinflammatory cytokine mRNA expression in spleens of mice exposed to the trichothecene vomitoxin. | 2003 | Toxicol. Sci. | pmid:12604842 |
| Plattner RD and Maragos CM | Determination of deoxynivalenol and nivalenol in corn and wheat by liquid chromatography with electrospray mass spectrometry. | 2003 Jan-Feb | J AOAC Int | pmid:12607741 |
| Lori GA et al. | Fusarium graminearum and deoxynivalenol contamination in the durum wheat area of Argentina. | 2003 | Microbiol. Res. | pmid:12608577 |
| Zhou WC et al. | Effect of individual Sumai 3 chromosomes on resistance to scab spread within spikes and deoxynivalenol accumulation within kernels in wheat. | 2002 | Hereditas | pmid:12627831 |
| Kos G et al. | Development of a method for the determination of Fusarium fungi on corn using mid-infrared spectroscopy with attenuated total reflection and chemometrics. | 2003 | Anal. Chem. | pmid:12641243 |
| Tiemann U et al. | Influence of the mycotoxins alpha- and beta-zearalenol and deoxynivalenol on the cell cycle of cultured porcine endometrial cells. | 2003 Mar-Apr | Reprod. Toxicol. | pmid:12642154 |
| Islam Z et al. | Differential induction of glucocorticoid-dependent apoptosis in murine lymphoid subpopulations in vivo following coexposure to lipopolysaccharide and vomitoxin (deoxynivalenol). | 2003 | Toxicol. Appl. Pharmacol. | pmid:12649039 |
| Moon Y and Pestka JJ | Cyclooxygenase-2 mediates interleukin-6 upregulation by vomitoxin (deoxynivalenol) in vitro and in vivo. | 2003 | Toxicol. Appl. Pharmacol. | pmid:12649040 |
| Moss MO | Fusarial toxins: are they a cause for concern? | 2003 | Vet. J. | pmid:12672361 |
| Pestka JJ | Deoxynivalenol-induced IgA production and IgA nephropathy-aberrant mucosal immune response with systemic repercussions. | 2003 | Toxicol. Lett. | pmid:12676476 |
| Nasir MS and Jolley ME | Fluorescence polarization (FP) assays for the determination of grain mycotoxins (fumonisins, DON vomitoxin and aflatoxins). | 2003 | Comb. Chem. High Throughput Screen. | pmid:12678705 |
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| Kim HS et al. | Polymorphism of trichothecene biosynthesis genes in deoxynivalenol- and nivalenol-producing Fusarium graminearum isolates. | 2003 | Mycol. Res. | pmid:12747330 |
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| Zhou HR et al. | Role of double-stranded RNA-activated protein kinase R (PKR) in deoxynivalenol-induced ribotoxic stress response. | 2003 | Toxicol. Sci. | pmid:12773753 |
| Islam Z and Pestka JJ | Role of IL-1(beta) in endotoxin potentiation of deoxynivalenol-induced corticosterone response and leukocyte apoptosis in mice. | 2003 | Toxicol. Sci. | pmid:12773775 |
| Weiss R et al. | Improving methods of analysis for mycotoxins: molecularly imprinted polymers for deoxynivalenol and zearalenone. | 2003 | Food Addit Contam | pmid:12775482 |
| Rasmussen PH et al. | Deoxynivalenol and other Fusarium toxins in wheat and rye flours on the Danish market. | 2003 | Food Addit Contam | pmid:12775483 |
| Omurtag GZ and BeyoÄŸlu D | Occurrence of deoxynivalenol (vomitoxin) in processed cereals and pulses in Turkey. | 2003 | Food Addit Contam | pmid:12775484 |
| Lutz MP et al. | Mycotoxigenic Fusarium and deoxynivalenol production repress chitinase gene expression in the biocontrol agent Trichoderma atroviride P1. | 2003 | Appl. Environ. Microbiol. | pmid:12788701 |
| Hope R and Magan N | Two-dimensional environmental profiles of growth, deoxynivalenol and nivalenol production by Fusarium culmorum on a wheat-based substrate. | 2003 | Lett. Appl. Microbiol. | pmid:12803560 |
| Samar MM et al. | Distribution of deoxynivalenol in wheat, wheat flour, bran, and gluten, and variability associated with the test procedure. | 2003 May-Jun | J AOAC Int | pmid:12852575 |
| Cirillo T et al. | Natural co-occurrence of deoxynivalenol and fumonisins B1 and B2 in Italian marketed foodstuffs. | 2003 | Food Addit Contam | pmid:12881130 |
| Somers DJ et al. | Molecular mapping of novel genes controlling Fusarium head blight resistance and deoxynivalenol accumulation in spring wheat. | 2003 | Genome | pmid:12897863 |
| House JD et al. | Deoxynivalenol removal from barley intended as swine feed through the use of an abrasive pearling procedure. | 2003 | J. Agric. Food Chem. | pmid:12903987 |
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| Poppenberger B et al. | Detoxification of the Fusarium mycotoxin deoxynivalenol by a UDP-glucosyltransferase from Arabidopsis thaliana. | 2003 | J. Biol. Chem. | pmid:12970342 |
| Park KJ et al. | Natural occurrence of Fusarium mycotoxins of the 1990 barley crop in Korea. | 1992 Nov-Dec | Food Addit Contam | pmid:1302203 |
| Tüdös AJ et al. | Rapid surface plasmon resonance-based inhibition assay of deoxynivalenol. | 2003 | J. Agric. Food Chem. | pmid:13129282 |
| Ayral AM et al. | In vitro effect of diacetoxyscirpenol and deoxynivalenol on microbicidal activity of murine peritoneal macrophages. | 1992 | Mycopathologia | pmid:1336129 |
| Rizzo AF et al. | The hemolytic activity of deoxynivalenol and T-2 toxin. | 1992 | Nat. Toxins | pmid:1344904 |
| Prelusky DB et al. | Effect of deoxynivalenol on neurotransmitters in discrete regions of swine brain. | 1992 | Arch. Environ. Contam. Toxicol. | pmid:1372799 |
| Diekman MA and Green ML | Mycotoxins and reproduction in domestic livestock. | 1992 | J. Anim. Sci. | pmid:1388147 |
| Gilbert J et al. | Deoxynivalenol in wheat and maize flour reference materials. 1. An intercomparison of methods. | 1992 Jan-Feb | Food Addit Contam | pmid:1397392 |
| Rotter BA et al. | Investigations in the use of mice exposed to mycotoxins as a model for growing pigs. | 1992 | J Toxicol Environ Health | pmid:1404488 |
| Bosch U and Mirocha CJ | Toxin production by Fusarium species from sugar beets and natural occurrence of zearalenone in beets and beet fibers. | 1992 | Appl. Environ. Microbiol. | pmid:1444361 |
| Zielonka L et al. | Influence of low doses of deoxynivalenol applied per os on chosen indexes of immune response in swine. | 2003 | Pol J Vet Sci | pmid:14509371 |
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| Alexander NJ et al. | Expression of Tri15 in Fusarium sporotrichioides. | 2004 | Curr. Genet. | pmid:14624310 |
| Usleber E et al. | Studies on the application of enzyme immunoassays for the Fusarium mycotoxins deoxynivalenol, 3-acetyldeoxynivalenol, and zearalenone. | 1992 | Zentralblatt Veterinarmedizin Reihe B | pmid:1462727 |
| Minervini F et al. | Toxicity and apoptosis induced by the mycotoxins nivalenol, deoxynivalenol and fumonisin B1 in a human erythroleukemia cell line. | 2004 | Toxicol In Vitro | pmid:14630058 |
| Chung YJ et al. | Transcriptional and posttranscriptional roles for p38 mitogen-activated protein kinase in upregulation of TNF-alpha expression by deoxynivalenol (vomitoxin). | 2003 | Toxicol. Appl. Pharmacol. | pmid:14644621 |
| Froquet R et al. | Do trichothecenes reduce viability of circulating blood cells and modify haemostasis parameters? | 2003 | Mycopathologia | pmid:14682462 |
| Simpson DR et al. | Competitive interactions between Microdochium nivale var. majus, M. nivale var. nivale and Fusarium culmorum in planta and in vitro. | 2004 | Environ. Microbiol. | pmid:14686944 |
| Cirillo T et al. | Evaluation of conventional and organic italian foodstuffs for deoxynivalenol and fumonisins B(1) and B(2). | 2003 | J. Agric. Food Chem. | pmid:14690407 |
| Moon Y and Pestka JJ | Deoxynivalenol-induced mitogen-activated protein kinase phosphorylation and IL-6 expression in mice suppressed by fish oil. | 2003 | J. Nutr. Biochem. | pmid:14690764 |
| Peng SQ and Yang JS | [Effect of deoxynivalenol on action potentials of cultured cardiomyocytes and the protective effects of selenium]. | 2003 | Zhonghua Yu Fang Yi Xue Za Zhi | pmid:14703497 |
| Yumbe-Guevara BE et al. | Effects of heating procedures on deoxynivalenol, nivalenol and zearalenone levels in naturally contaminated barley and wheat. | 2003 | Food Addit Contam | pmid:14726277 |
| MacDonald S et al. | Survey of ochratoxin A and deoxynivalenol in stored grains from the 1999 harvest in the UK. | 2004 | Food Addit Contam | pmid:14754640 |
| He P et al. | Microbial transformation of deoxynivalenol (vomitoxin). | 1992 | Appl. Environ. Microbiol. | pmid:1476428 |
| Bergsjø B et al. | Effects of diets with graded levels of deoxynivalenol on performance in growing pigs. | 1992 | Zentralbl Veterinarmed A | pmid:1492508 |
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| Brown DW et al. | Functional demarcation of the Fusarium core trichothecene gene cluster. | 2004 | Fungal Genet. Biol. | pmid:14998528 |
| Rasooly L and Pestka JJ | Vomitoxin-induced dysregulation of serum IgA, IgM and IgG reactive with gut bacterial and self antigens. | 1992 | Food Chem. Toxicol. | pmid:1500035 |
| Bily AC et al. | Analysis of Fusarium graminearum mycotoxins in different biological matrices by LC/MS. | 2004 | Mycopathologia | pmid:15008354 |
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| Sundstøl Eriksen G et al. | Comparative cytotoxicity of deoxynivalenol, nivalenol, their acetylated derivatives and de-epoxy metabolites. | 2004 | Food Chem. Toxicol. | pmid:15019186 |
| Choi GH et al. | Cloning, expression, and characterization of single-chain variable fragment antibody against mycotoxin deoxynivalenol in recombinant Escherichia coli. | 2004 | Protein Expr. Purif. | pmid:15039070 |
| Avantaggiato G et al. | Evaluation of the intestinal absorption of deoxynivalenol and nivalenol by an in vitro gastrointestinal model, and the binding efficacy of activated carbon and other adsorbent materials. | 2004 | Food Chem. Toxicol. | pmid:15046828 |
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| Manthey FA et al. | Microbial loads, mycotoxins, and quality of durum wheat from the 2001 harvest of the northern plains region of the United States. | 2004 | J. Food Prot. | pmid:15083730 |
| Dänicke S et al. | Effects of graded levels of Fusarium toxin contaminated wheat in diets for fattening pigs on growth performance, nutrient digestibility, deoxynivalenol balance and clinical serum characteristics. | 2004 | Arch Anim Nutr | pmid:15085961 |
| Swamy HV et al. | Effects of feeding blends of grains naturally contaminated with Fusarium mycotoxins on growth and immunological parameters of broiler chickens. | 2004 | Poult. Sci. | pmid:15109051 |
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| Jia Q et al. | Docosahexaenoic acid and eicosapentaenoic acid, but not alpha-linolenic acid, suppress deoxynivalenol-induced experimental IgA nephropathy in mice. | 2004 | J. Nutr. | pmid:15173396 |
| Dänicke S et al. | On the toxicokinetics and the metabolism of deoxynivalenol (DON) in the pig. | 2004 | Arch Anim Nutr | pmid:15195910 |
| Papadopoulou-Bouraoui A et al. | Screening survey of deoxynivalenol in beer from the European market by an enzyme-linked immunosorbent assay. | 2004 | Food Addit Contam | pmid:15204540 |
| Drochner W et al. | Serum IgA-promoting effects induced by feed loads containing isolated deoxynivalenol (DON) in growing piglets. | 2004 | J. Toxicol. Environ. Health Part A | pmid:15205033 |
| Dänicke S et al. | Effects of graded levels of Fusarium-toxin-contaminated wheat in Pekin duck diets on performance, health and metabolism of deoxynivalenol and zearalenone. | 2004 | Br. Poult. Sci. | pmid:15222424 |
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| Hsia CC et al. | Nivalenol, a main Fusarium toxin in dietary foods from high-risk areas of cancer of esophagus and gastric cardia in China, induced benign and malignant tumors in mice. | 2004 | Oncol. Rep. | pmid:15254715 |
| Tanaka K et al. | Natural occurrence of trichothecenes on lodged and water-damaged domestic rice in Japan. | 2004 | Shokuhin Eiseigaku Zasshi | pmid:15272601 |
| Krska R et al. | Purity assessment of commercially available crystalline deoxynivalenol. | 2004 Jul-Aug | J AOAC Int | pmid:15295885 |
| Swamy HV et al. | Effects of feeding blends of grains naturally contaminated with Fusarium mycotoxins on brain regional neurochemistry of starter pigs and broiler chickens. | 2004 | J. Anim. Sci. | pmid:15309961 |
| Sypecka Z et al. | Deoxynivalenol and zearalenone residues in eggs of laying hens fed with a naturally contaminated diet: effects on egg production and estimation of transmission rates from feed to eggs. | 2004 | J. Agric. Food Chem. | pmid:15315386 |
| Larsen JC et al. | Workshop on trichothecenes with a focus on DON: summary report. | 2004 | Toxicol. Lett. | pmid:15342076 |
| Edwards SG | Influence of agricultural practices on fusarium infection of cereals and subsequent contamination of grain by trichothecene mycotoxins. | 2004 | Toxicol. Lett. | pmid:15342078 |
| Snijders CH | Resistance in wheat to Fusarium infection and trichothecene formation. | 2004 | Toxicol. Lett. | pmid:15342079 |
| Hazel CM and Patel S | Influence of processing on trichothecene levels. | 2004 | Toxicol. Lett. | pmid:15342081 |
| Pestka JJ et al. | Cellular and molecular mechanisms for immune modulation by deoxynivalenol and other trichothecenes: unraveling a paradox. | 2004 | Toxicol. Lett. | pmid:15342082 |
| Schlatter J | Toxicity data relevant for hazard characterization. | 2004 | Toxicol. Lett. | pmid:15342084 |
| Koch P | State of the art of trichothecenes analysis. | 2004 | Toxicol. Lett. | pmid:15342087 |
| Schneider E et al. | Rapid methods for deoxynivalenol and other trichothecenes. | 2004 | Toxicol. Lett. | pmid:15342088 |
| Pieters MN et al. | Reduced intake of deoxynivalenol in The Netherlands: a risk assessment update. | 2004 | Toxicol. Lett. | pmid:15342091 |
| Tutelyan VA | Deoxynivalenol in cereals in Russia. | 2004 | Toxicol. Lett. | pmid:15342094 |
| Visconti A et al. | Reduction of deoxynivalenol during durum wheat processing and spaghetti cooking. | 2004 | Toxicol. Lett. | pmid:15342095 |
| Instanes C and Hetland G | Deoxynivalenol (DON) is toxic to human colonic, lung and monocytic cell lines, but does not increase the IgE response in a mouse model for allergy. | 2004 | Toxicology | pmid:15369845 |
| Royer D et al. | Quantitative analysis of Fusarium mycotoxins in maize using accelerated solvent extraction before liquid chromatography/atmospheric pressure chemical ionization tandem mass spectrometry. | 2004 | Food Addit Contam | pmid:15370841 |
| Kinser S et al. | Gene expression profiling in spleens of deoxynivalenol-exposed mice: immediate early genes as primary targets. | 2004 | J. Toxicol. Environ. Health Part A | pmid:15371230 |
| Mikami O et al. | Porcine hepatocyte apoptosis and reduction of albumin secretion induced by deoxynivalenol. | 2004 | Toxicology | pmid:15388250 |
| Champeil A et al. | Effects of grain sampling procedures on fusarium mycotoxin assays in wheat grains. | 2004 | J. Agric. Food Chem. | pmid:15453665 |
| Sugita-Konishi Y et al. | [Evaluation of three commercial ELISA kits for rapid screening of deoxynivalenol in unpolished wheat]. | 2004 | Shokuhin Eiseigaku Zasshi | pmid:15468936 |