Vomitoxin
Vomitoxin is a lipid of Prenol Lipids (PR) class. Vomitoxin is associated with abnormalities such as Infection and Gastroenteritis. The involved functions are known as mRNA Expression, Inflammation, Transcription, Genetic, Protein Biosynthesis and Adverse effects. Vomitoxin often locates in Lymphoid Tissue, Immune system, Bone Marrow and Plasma membrane. The associated genes with Vomitoxin are IMPACT gene, HIST1H1C gene and RBM39 gene. The related experimental models are Mouse Model.
Cross Reference
Introduction
To understand associated biological information of Vomitoxin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Vomitoxin?
Vomitoxin is suspected in Infection, Gastroenteritis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Vomitoxin
PubChem Associated disorders and diseases
What pathways are associated with Vomitoxin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Vomitoxin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Vomitoxin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Vomitoxin?
There are no associated biomedical information in the current reference collection.
What genes are associated with Vomitoxin?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Vomitoxin?
Mouse Model
Mouse Model are used in the study 'Dietary fish oil suppresses experimental immunoglobulin a nephropathy in mice.' (Pestka JJ et al., 2002).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Vomitoxin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Sprando RL et al. | The effect of vomitoxin (Deoxnivalenol) on testicular morphology, testicular spermatid counts and epididymal sperm counts in IL-6KO [B6129-IL6 [TmlKopf] (IL-6 gene deficient)] and WT [B6129F2 (wild type to B6129-IL6 with an intact IL-6 gene)] mice. | 1999 | Food Chem. Toxicol. | pmid:10566878 |
| Hsueh CC et al. | Indirect electrochemical detection of type-B trichothecene mycotoxins. | 1999 | Anal. Chem. | pmid:10500491 |
| Thuvander A et al. | In vitro exposure of human lymphocytes to trichothecenes: individual variation in sensitivity and effects of combined exposure on lymphocyte function. | 1999 | Food Chem. Toxicol. | pmid:10478832 |
| Groves FD et al. | Fusarium mycotoxins in corn and corn products in a high-risk area for gastric cancer in Shandong Province, China. | 1999 May-Jun | J AOAC Int | pmid:10367384 |
| Wang H et al. | [Effects of deoxynivalenol on proliferation and tumor necrosis factor-alpha secretion of human peripheral blood mononuclear cells in vitro]. | 2000 | Wei Sheng Yan Jiu | pmid:12520964 |
| Li S et al. | Modulation of transcription factor AP-1 activity in murine EL-4 thymoma cells by vomitoxin (deoxynivalenol). | 2000 | Toxicol. Appl. Pharmacol. | pmid:10662601 |
| Yang GH et al. | Down-regulation of the endoplasmic reticulum chaperone GRP78/BiP by vomitoxin (Deoxynivalenol). | 2000 | Toxicol. Appl. Pharmacol. | pmid:10652249 |
| Wuchiyama J et al. | A trichothecene efflux pump encoded by Tri102 in the biosynthesis gene cluster of Fusarium graminearum. | 2000 | J. Antibiot. | pmid:10805582 |
| Yang GH et al. | Apoptosis induction by the satratoxins and other trichothecene mycotoxins: relationship to ERK, p38 MAPK, and SAPK/JNK activation. | 2000 | Toxicol. Appl. Pharmacol. | pmid:10764628 |
| Moreno Contreras MC et al. | [Determination of deoxynivalenol (DON) in wheat, barley and corn and its relationship with the levels of total molds, Fusarium spp., colonization percentage and water activity]. | 2000 | Arch Latinoam Nutr | pmid:11048592 |
| Reid LM et al. | Pre-harvest accumulation of deoxynivalenol in sweet corn ears inoculated with Fusarium graminearum. | 2000 | Food Addit Contam | pmid:11027030 |
| Rafai P et al. | Evaluation of mycotoxin-contaminated cereals for their use in animal feeds in Hungary. | 2000 | Food Addit Contam | pmid:11091794 |
| May HD et al. | Effects of the Fusarium spp. mycotoxins fusaric acid and deoxynivalenol on the growth of Ruminococcus albus and Methanobrevibacter ruminantium. | 2000 | Can. J. Microbiol. | pmid:10941514 |
| Pestka JJ and Zhou HR | Interleukin-6-deficient mice refractory to IgA dysregulation but not anorexia induction by vomitoxin (deoxynivalenol) ingestion. | 2000 | Food Chem. Toxicol. | pmid:10942317 |
| Zhou HR et al. | Lipopolysaccharide and the trichothecene vomitoxin (deoxynivalenol) synergistically induce apoptosis in murine lymphoid organs. | 2000 | Toxicol. Sci. | pmid:10696773 |
| Desjardins AE et al. | Fusarium species from nepalese rice and production of mycotoxins and gibberellic acid by selected species. | 2000 | Appl. Environ. Microbiol. | pmid:10698766 |
| Boeira LS et al. | The effect of combinations of Fusarium mycotoxins (deoxynivalenol, zearalenone and fumonisin B1) on growth of brewing yeasts. | 2000 | J. Appl. Microbiol. | pmid:10747219 |
| Schneider L et al. | An enzyme linked immunoassay for the determination of deoxynivalenol in wheat based on chicken egg yolk antibodies. | 2000 | Fresenius J Anal Chem | pmid:11227446 |
| Birzele B et al. | Deoxynivalenol and ochratoxin A in German wheat and changes of level in relation to storage parameters. | 2000 | Food Addit Contam | pmid:11271837 |
| Fazekas B et al. | Natural deoxynivalenol (DON) contamination of wheat samples grown in 1998 as determined by high-performance liquid chromatography. | 2000 | Acta Vet. Hung. | pmid:11402697 |
| Freese L et al. | Variability of deoxynivalenol measurements in barley. | 2000 Sep-Oct | J AOAC Int | pmid:11048870 |
| Whitaker TB et al. | Sampling, sample preparation, and analytical variability associated with testing wheat for deoxynivalenol. | 2000 Sep-Oct | J AOAC Int | pmid:11048874 |
| Machado LC and Kemmelmeier C | Identification of deoxynivalenol, 3-acetyldeoxynivalenol and zearalenone in the galactose oxidase-producing fungus Dactylium dendroides. | 2001 | Mycopathologia | pmid:11265166 |
| Malone B | Solution fluorometric method for deoxynivalenol in grains. | 2001 | Methods Mol. Biol. | pmid:11050997 |
| Yoshizawa T | Chromatographic methods for trichothecenes. | 2001 | Methods Mol. Biol. | pmid:11050998 |
| Cooney JM et al. | Impact of competitive fungi on Trichothecene production by Fusarium graminearum. | 2001 | J. Agric. Food Chem. | pmid:11170621 |
| Grabarkiewicz-Szczesna J et al. | Fusariotoxins in kernels of winter wheat cultivars field samples collected during 1993 in Poland. | 2001 | Nahrung | pmid:11253636 |
| Langseth W et al. | Production of culmorin compounds and other secondary metabolites by Fusarium culmorum and F. graminearum strains isolated from Norwegian cereals. | 2001 | Mycopathologia | pmid:11694092 |
| Froquet R et al. | Improvement of megakaryocytic progenitor culture for toxicological investigations. | 2001 | Toxicol In Vitro | pmid:11698171 |
| Martins ML and Martins HM | Determination of deoxynivalenol in wheat-based breakfast cereals marketed in Portugal. | 2001 | J. Food Prot. | pmid:11726173 |
| Samar MM et al. | Effect of fermentation on naturally occurring deoxynivalenol (DON) in Argentinean bread processing technology. | 2001 | Food Addit Contam | pmid:11665728 |
| Widestrand J and Pettersson H | Effect of time, temperature and solvent on the stability of T-2 toxin, HT-2 toxin, deoxynivalenol and nivalenol calibrants. | 2001 | Food Addit Contam | pmid:11665740 |
| Debouck C et al. | Skeletal deformities induced by the intraperitoneal administration of deoxynivalenol (vomitoxin) in mice. | 2001 | Int Orthop | pmid:11482540 |
| Krysińska-Traczyk E et al. | Levels of fungi and mycotoxins in samples of grain and grain dust collected on farms in Eastern Poland. | 2001 | Ann Agric Environ Med | pmid:11748887 |
| Ghebremeskel M and Langseth W | The occurrence of culmorin and hydroxy-culmorins in cereals. | 2001 | Mycopathologia | pmid:11761144 |
| Sugita-Konishi Y and Pestka JJ | Differential upregulation of TNF-alpha, IL-6, and IL-8 production by deoxynivalenol (vomitoxin) and other 8-ketotrichothecenes in a human macrophage model. | 2001 | J. Toxicol. Environ. Health Part A | pmid:11766169 |
| Wong S et al. | Superinduction of TNF-alpha and IL-6 in macrophages by vomitoxin (deoxynivalenol) modulated by mRNA stabilization. | 2001 | Toxicology | pmid:11295263 |
| Edwards SG et al. | Quantification of trichothecene-producing Fusarium species in harvested grain by competitive PCR to determine efficacies of fungicides against Fusarium head blight of winter wheat. | 2001 | Appl. Environ. Microbiol. | pmid:11282607 |
| Brown DW et al. | A genetic and biochemical approach to study trichothecene diversity in Fusarium sporotrichioides and Fusarium graminearum. | 2001 | Fungal Genet. Biol. | pmid:11352533 |
| Fink-Gremmels J | [An alternative view. Mycotoxins and mycoses]. | 2001 | Tijdschr Diergeneeskd | pmid:11285646 |
| Froquet R et al. | Trichothecene toxicity on human megakaryocyte progenitors (CFU-MK). | 2001 | Hum Exp Toxicol | pmid:11327514 |
| Lee T et al. | Identification of deoxynivalenol- and nivalenol-producing chemotypes of Gibberella zeae by using PCR. | 2001 | Appl. Environ. Microbiol. | pmid:11425709 |
| Mateo JJ et al. | Critical study of and improvements in chromatographic methods for the analysis of type B trichothecenes. | 2001 | J Chromatogr A | pmid:11403460 |
| Meky FA et al. | Deoxynivalenol-induced immunomodulation of human lymphocyte proliferation and cytokine production. | 2001 | Food Chem. Toxicol. | pmid:11434990 |
| Cazzaniga D et al. | Mycotoxins inactivation by extrusion cooking of corn flour. | 2001 | Lett. Appl. Microbiol. | pmid:11472523 |
| Okubara PA et al. | Engineering deoxynivalenol metabolism in wheat through the expression of a fungal trichothecene acetyltransferase gene. | 2002 | Theor. Appl. Genet. | pmid:12582873 |
| Rodrigues-Fo E et al. | Electron ionization mass spectral fragmentation of deoxynivalenol and related tricothecenes. | 2002 | Rapid Commun. Mass Spectrom. | pmid:12271447 |
| Urban M et al. | Arabidopsis is susceptible to the cereal ear blight fungal pathogens Fusarium graminearum and Fusarium culmorum. | 2002 | Plant J. | pmid:12492838 |
| Leblanc JC et al. | Simulation of the exposure to deoxynivalenol of French consumers of organic and conventional foodstuffs. | 2002 | Regul. Toxicol. Pharmacol. | pmid:12460749 |
| Eriksen GS et al. | Transformation of trichothecenes in ileal digesta and faeces from pigs. | 2002 | Arch Tierernahr | pmid:12462911 |
| Moon Y and Pestka JJ | Vomitoxin-induced cyclooxygenase-2 gene expression in macrophages mediated by activation of ERK and p38 but not JNK mitogen-activated protein kinases. | 2002 | Toxicol. Sci. | pmid:12377986 |
| Swamy HV et al. | Effects of feeding blends of grains naturally contaminated with Fusarium mycotoxins on production and metabolism in broilers. | 2002 | Poult. Sci. | pmid:12162357 |
| Dänicke S et al. | Effect of addition of a detoxifying agent to laying hen diets containing uncontaminated or Fusarium toxin-contaminated maize on performance of hens and on carryover of zearalenone. | 2002 | Poult. Sci. | pmid:12455595 |
| Yang GH and Pestka JJ | Vomitoxin (deoxynivalenol)-mediated inhibition of nuclear protein binding to NRE-A, an IL-2 promoter negative regulatory element, in EL-4 cells. | 2002 | Toxicology | pmid:11893416 |
| Berek L et al. | The immunosuppressive effect of Fusarium mycotoxin as a function of HLA antigens. | 2002 | Acta Microbiol Immunol Hung | pmid:12073830 |
| Pestka JJ et al. | Dietary fish oil suppresses experimental immunoglobulin a nephropathy in mice. | 2002 | J. Nutr. | pmid:11823588 |
| Olsson J et al. | Detection and quantification of ochratoxin A and deoxynivalenol in barley grains by GC-MS and electronic nose. | 2002 | Int. J. Food Microbiol. | pmid:11845819 |
| Maragos CM and Plattner RD | Rapid fluorescence polarization immunoassay for the mycotoxin deoxynivalenol in wheat. | 2002 | J. Agric. Food Chem. | pmid:11902919 |
| Lombaert GA | Methods for the determination of deoxynivalenol and other trichothecenes in foods. | 2002 | Adv. Exp. Med. Biol. | pmid:11922082 |
| Trigo-Stockli DM | Effect of processing on deoxynivalenol and other trichothecenes. | 2002 | Adv. Exp. Med. Biol. | pmid:11922085 |
| Schaafsma AW | Economic changes imposed by mycotoxins in food grains: case study of deoxynivalenol in winter wheat. | 2002 | Adv. Exp. Med. Biol. | pmid:11922094 |
| Schisler DA et al. | Biological control of Fusarium head blight of wheat and deoxynivalenol levels in grain via use of microbial antagonists. | 2002 | Adv. Exp. Med. Biol. | pmid:11922099 |
| Whitaker TB et al. | Sampling wheat for deoxynivalenol. | 2002 | Adv. Exp. Med. Biol. | pmid:11922100 |
| Islam Z et al. | Endotoxin potentiation of trichothecene-induced lymphocyte apoptosis is mediated by up-regulation of glucocorticoids. | 2002 | Toxicol. Appl. Pharmacol. | pmid:11922776 |
| Pieters MN et al. | Risk assessment of deoxynivalenol in food: concentration limits, exposure and effects. | 2002 | Adv. Exp. Med. Biol. | pmid:11924598 |
| Wong SS et al. | Effects of vomitoxin (deoxynivalenol) on the binding of transcription factors AP-1, NF-kappaB, and NF-IL6 in raw 264.7 macrophage cells. | 2002 | J. Toxicol. Environ. Health Part A | pmid:12167214 |
| Pestka JJ and Zhou HR | Effects of tumor necrosis factor type 1 and 2 receptor deficiencies on anorexia, growth and IgA dysregulation in mice exposed to the trichothecene vomitoxin. | 2002 | Food Chem. Toxicol. | pmid:12176089 |
| Bai GH et al. | Deoxynivalenol-nonproducing fusarium graminearum causes initial infection, but does not cause disease spread in wheat spikes. | 2002 | Mycopathologia | pmid:12000132 |
| Lee T et al. | Tri13 and Tri7 determine deoxynivalenol- and nivalenol-producing chemotypes of Gibberella zeae. | 2002 | Appl. Environ. Microbiol. | pmid:11976083 |
| Maragos CM et al. | Fluorescence polarization as a tool for the determination of deoxynivalenol in wheat. | 2002 | Food Addit Contam | pmid:11962698 |
| Schnerr H et al. | Correlation between DNA of trichothecene-producing Fusarium species and deoxynivalenol concentrations in wheat-samples. | 2002 | Lett. Appl. Microbiol. | pmid:12100586 |
| Szkudelska K et al. | Short-time deoxynivalenol treatment induces metabolic disturbances in the rat. | 2002 | Toxicol. Lett. | pmid:12368054 |
| Alm H et al. | The influence of the mycotoxins deoxynivalenol and zearalenol on in vitro maturation of pig oocytes and in vitro culture of pig zygotes. | 2002 | Toxicol In Vitro | pmid:12423645 |
| Bakan B et al. | Identification by PCR of Fusarium culmorum strains producing large and small amounts of deoxynivalenol. | 2002 | Appl. Environ. Microbiol. | pmid:12406740 |
| Maresca M et al. | The mycotoxin deoxynivalenol affects nutrient absorption in human intestinal epithelial cells. | 2002 | J. Nutr. | pmid:12221236 |
| Zhou WC et al. | Effect of individual Sumai 3 chromosomes on resistance to scab spread within spikes and deoxynivalenol accumulation within kernels in wheat. | 2002 | Hereditas | pmid:12627831 |
| Schollenberger M et al. | Fusarium toxins in wheat flour collected in an area in southwest Germany. | 2002 | Int. J. Food Microbiol. | pmid:11843417 |
| Perkowski J and Kaczmarek Z | Distribution of deoxynivalenol and 3-acetyldeoxynivalenol in naturally contaminated and Fusarium culmorum infected triticale samples. | 2002 | Nahrung | pmid:12577591 |
| Etzel RA | Mycotoxins. | 2002 Jan 23-30 | JAMA | pmid:11798344 |
| Rupp HS | Determination of deoxynivalenol in whole wheat flour and wheat bran. | 2002 Nov-Dec | J AOAC Int | pmid:12477199 |
| Chung YJ et al. | Up-regulation of macrophage inflammatory protein-2 and complement 3A receptor by the trichothecenes deoxynivalenol and satratoxin G. | 2003 | Toxicology | pmid:12604170 |
| Zhou HR et al. | Rapid, sequential activation of mitogen-activated protein kinases and transcription factors precedes proinflammatory cytokine mRNA expression in spleens of mice exposed to the trichothecene vomitoxin. | 2003 | Toxicol. Sci. | pmid:12604842 |
| Lori GA et al. | Fusarium graminearum and deoxynivalenol contamination in the durum wheat area of Argentina. | 2003 | Microbiol. Res. | pmid:12608577 |
| Clifford LJ et al. | An improved method for the purification of the trichothecene deoxynivalenol (vomitoxin) from Fusarium graminearum culture. | 2003 | J. Agric. Food Chem. | pmid:12517120 |
| Meky FA et al. | Development of a urinary biomarker of human exposure to deoxynivalenol. | 2003 | Food Chem. Toxicol. | pmid:12480302 |
| Cirillo T et al. | Natural co-occurrence of deoxynivalenol and fumonisins B1 and B2 in Italian marketed foodstuffs. | 2003 | Food Addit Contam | pmid:12881130 |
| Somers DJ et al. | Molecular mapping of novel genes controlling Fusarium head blight resistance and deoxynivalenol accumulation in spring wheat. | 2003 | Genome | pmid:12897863 |
| House JD et al. | Deoxynivalenol removal from barley intended as swine feed through the use of an abrasive pearling procedure. | 2003 | J. Agric. Food Chem. | pmid:12903987 |
| Krysińska-Traczyk E et al. | [Filamentous fungi and mycotoxins as potential occupational risk factors among farmers harvesting various crops]. | 2003 | Med Pr | pmid:12923995 |
| Weiss R et al. | Improving methods of analysis for mycotoxins: molecularly imprinted polymers for deoxynivalenol and zearalenone. | 2003 | Food Addit Contam | pmid:12775482 |
| Wilbert FM and Kemmelmeier C | Identification of deoxynivalenol, 3-acetyldeoxynivalenol, and zearalenone in galactose oxidase-producing isolates of Fusarium graminearum. | 2003 | J. Basic Microbiol. | pmid:12746857 |
| Kos G et al. | Development of a method for the determination of Fusarium fungi on corn using mid-infrared spectroscopy with attenuated total reflection and chemometrics. | 2003 | Anal. Chem. | pmid:12641243 |
| Lutz MP et al. | Mycotoxigenic Fusarium and deoxynivalenol production repress chitinase gene expression in the biocontrol agent Trichoderma atroviride P1. | 2003 | Appl. Environ. Microbiol. | pmid:12788701 |
| Hope R and Magan N | Two-dimensional environmental profiles of growth, deoxynivalenol and nivalenol production by Fusarium culmorum on a wheat-based substrate. | 2003 | Lett. Appl. Microbiol. | pmid:12803560 |
| Islam Z et al. | Differential induction of glucocorticoid-dependent apoptosis in murine lymphoid subpopulations in vivo following coexposure to lipopolysaccharide and vomitoxin (deoxynivalenol). | 2003 | Toxicol. Appl. Pharmacol. | pmid:12649039 |
| Moon Y and Pestka JJ | Cyclooxygenase-2 mediates interleukin-6 upregulation by vomitoxin (deoxynivalenol) in vitro and in vivo. | 2003 | Toxicol. Appl. Pharmacol. | pmid:12649040 |
| Sugita-Konishi Y | [Current worldwide regulation for mycotoxins]. | 2003 | Shokuhin Eiseigaku Zasshi | pmid:12749204 |
| Moss MO | Fusarial toxins: are they a cause for concern? | 2003 | Vet. J. | pmid:12672361 |
| Nasir MS and Jolley ME | Fluorescence polarization (FP) assays for the determination of grain mycotoxins (fumonisins, DON vomitoxin and aflatoxins). | 2003 | Comb. Chem. High Throughput Screen. | pmid:12678705 |
| Dänicke S et al. | Effects of graded levels of Fusarium toxin-contaminated wheat and of a detoxifying agent in broiler diets on performance, nutrient digestibility and blood chemical parameters. | 2003 | Br. Poult. Sci. | pmid:12737233 |