Vomitoxin is a lipid of Prenol Lipids (PR) class. Vomitoxin is associated with abnormalities such as Infection and Gastroenteritis. The involved functions are known as mRNA Expression, Inflammation, Transcription, Genetic, Protein Biosynthesis and Adverse effects. Vomitoxin often locates in Lymphoid Tissue, Immune system, Bone Marrow and Plasma membrane. The associated genes with Vomitoxin are IMPACT gene, HIST1H1C gene and RBM39 gene. The related experimental models are Mouse Model.
To understand associated biological information of Vomitoxin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Vomitoxin is suspected in Infection, Gastroenteritis and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Vomitoxin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Dietary fish oil suppresses experimental immunoglobulin a nephropathy in mice.' (Pestka JJ et al., 2002).
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Authors | Title | Published | Journal | PubMed Link |
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Flannery BM et al. | Evaluation of insulin-like growth factor acid-labile subunit as a potential biomarker of effect for deoxynivalenol-induced proinflammatory cytokine expression. | 2013 | Toxicology | pmid:23298694 |
Gratz SW et al. | The human fecal microbiota metabolizes deoxynivalenol and deoxynivalenol-3-glucoside and may be responsible for urinary deepoxy-deoxynivalenol. | 2013 | Appl. Environ. Microbiol. | pmid:23315729 |
Pietsch C et al. | Occurrence of deoxynivalenol and zearalenone in commercial fish feed: an initial study. | 2013 | Toxins (Basel) | pmid:23325300 |
Cano PM et al. | Deoxynivalenol as a new factor in the persistence of intestinal inflammatory diseases: an emerging hypothesis through possible modulation of Th17-mediated response. | 2013 | PLoS ONE | pmid:23326479 |
Fu J et al. | Cystathionine gamma-synthase is essential for methionine biosynthesis in Fusarium graminearum. | 2013 | Fungal Biol | pmid:23332829 |
Armando MR et al. | In vitro study on the effect of Saccharomyces cerevisiae strains on growth and mycotoxin production by Aspergillus carbonarius and Fusarium graminearum. | 2013 | Int. J. Food Microbiol. | pmid:23334096 |
Rohweder D et al. | Bioavailability of the Fusarium toxin deoxynivalenol (DON) from wheat straw and chaff in pigs. | 2013 | Arch Anim Nutr | pmid:23336299 |
Dall'Erta A et al. | Masked mycotoxins are efficiently hydrolyzed by human colonic microbiota releasing their aglycones. | 2013 | Chem. Res. Toxicol. | pmid:23347206 |
Pan X et al. | Global protein phosphorylation dynamics during deoxynivalenol-induced ribotoxic stress response in the macrophage. | 2013 | Toxicol. Appl. Pharmacol. | pmid:23352502 |
Hirano S and Kataoka T | Deoxynivalenol induces ectodomain shedding of TNF receptor 1 and thereby inhibits the TNF-α-induced NF-κB signaling pathway. | 2013 | Eur. J. Pharmacol. | pmid:23357557 |
Uhlig S et al. | Enzyme-assisted synthesis and structural characterization of the 3-, 8-, and 15-glucuronides of deoxynivalenol. | 2013 | J. Agric. Food Chem. | pmid:23374009 |
Li S et al. | Water-based slow injection ultrasound-assisted emulsification microextraction for the determination of deoxynivalenol and de-epoxy-deoxynivalenol in maize and pork samples. | 2013 | Anal Bioanal Chem | pmid:23380955 |
Lee HM et al. | Development of a monoclonal antibody against deoxynivalenol for magnetic nanoparticle-based extraction and an enzyme-linked immunosorbent assay. | 2013 | J. Vet. Sci. | pmid:23388439 |
Lucioli J et al. | The food contaminant deoxynivalenol activates the mitogen activated protein kinases in the intestine: interest of ex vivo models as an alternative to in vivo experiments. | 2013 | Toxicon | pmid:23403092 |
Kalaiselvi P et al. | Cytoprotective effect of epigallocatechin-3-gallate against deoxynivalenol-induced toxicity through anti-oxidative and anti-inflammatory mechanisms in HT-29 cells. | 2013 | Food Chem. Toxicol. | pmid:23410590 |
Juan-GarcÃa A et al. | Applications of flow cytometry to toxicological mycotoxin effects in cultured mammalian cells: a review. | 2013 | Food Chem. Toxicol. | pmid:23422035 |
Gauthier T et al. | Deoxynivalenol impairs the immune functions of neutrophils. | 2013 | Mol Nutr Food Res | pmid:23427020 |
Yunus AW and Böhm J | Serum cation profile of broilers at various stages of exposure to deoxynivalenol. | 2013 | Mycotoxin Res | pmid:23430398 |
Choi BK et al. | Effects of oral deoxynivalenol exposure on immune-related parameters in lymphoid organs and serum of mice vaccinated with porcine parvovirus vaccine. | 2013 | Mycotoxin Res | pmid:23436220 |
Fan J et al. | Characterization of the sterol 14α-demethylases of Fusarium graminearum identifies a novel genus-specific CYP51 function. | 2013 | New Phytol. | pmid:23442154 |
Pasquali M et al. | FcStuA from Fusarium culmorum controls wheat foot and root rot in a toxin dispensable manner. | 2013 | PLoS ONE | pmid:23451228 |
Huang J et al. | [Determination of deoxynivalenol in grain and its products by solid-phase extraction coupled with high performance liquid chromatography-tandem mass spectrometry]. | 2012 | Se Pu | pmid:23451526 |
Wu W et al. | Peptide YY3-36 and 5-hydroxytryptamine mediate emesis induction by trichothecene deoxynivalenol (vomitoxin). | 2013 | Toxicol. Sci. | pmid:23457120 |
Krout-Greenberg ND et al. | Preliminary study to assess mycotoxin concentrations in whole corn in the California feed supply. | 2013 | J. Dairy Sci. | pmid:23462178 |
Yoshinari T et al. | Inter-laboratory study of an LC-MS/MS method for simultaneous determination of deoxynivalenol and its acetylated derivatives, 3-acetyl-deoxynivalenol and 15-acetyl-deoxynivalenol in wheat. | 2013 | Shokuhin Eiseigaku Zasshi | pmid:23470877 |
Tamura C et al. | Formulation of a pectin gel that efficiently traps mycotoxin deoxynivalenol and reduces its bioavailability. | 2013 | Carbohydr Polym | pmid:23499119 |
Kullik K et al. | Interactions between the Fusarium toxin deoxynivalenol and lipopolysaccharides on the in vivo protein synthesis of acute phase proteins, cytokines and metabolic activity of peripheral blood mononuclear cells in pigs. | 2013 | Food Chem. Toxicol. | pmid:23500770 |
Rampitsch C et al. | Comparative secretome analysis of Fusarium graminearum and two of its non-pathogenic mutants upon deoxynivalenol induction in vitro. | 2013 | Proteomics | pmid:23512867 |
Halawa A et al. | Intestinal transport of deoxynivalenol across porcine small intestines. | 2013 | Arch Anim Nutr | pmid:23521693 |
Rempe I et al. | Hydrothermal treatment of naturally contaminated maize in the presence of sodium metabisulfite, methylamine and calcium hydroxide; effects on the concentration of zearalenone and deoxynivalenol. | 2013 | Mycotoxin Res | pmid:23536360 |
Schweiger W et al. | Functional characterization of two clusters of Brachypodium distachyon UDP-glycosyltransferases encoding putative deoxynivalenol detoxification genes. | 2013 | Mol. Plant Microbe Interact. | pmid:23550529 |
Hou YJ et al. | Mycotoxin-containing diet causes oxidative stress in the mouse. | 2013 | PLoS ONE | pmid:23555961 |
Wan LY et al. | Individual and combined cytotoxic effects of Fusarium toxins (deoxynivalenol, nivalenol, zearalenone and fumonisins B1) on swine jejunal epithelial cells. | 2013 | Food Chem. Toxicol. | pmid:23562706 |
Subramaniam R and Rampitsch C | Towards systems biology of mycotoxin regulation. | 2013 | Toxins (Basel) | pmid:23598563 |
Dänicke S et al. | The Fusarium toxin deoxynivalenol (DON) modulates the LPS induced acute phase reaction in pigs. | 2013 | Toxicol. Lett. | pmid:23603058 |
Tan DC et al. | Mycotoxins produced by Fusarium spp. associated with Fusarium head blight of wheat in Western Australia. | 2012 | Mycotoxin Res | pmid:23606046 |
Pleadin J et al. | Mould and mycotoxin contamination of pig feed in northwest Croatia. | 2012 | Mycotoxin Res | pmid:23606122 |
Sugiyama K et al. | Thioredoxin-1 contributes to protection against DON-induced oxidative damage in HepG2 cells. | 2012 | Mycotoxin Res | pmid:23606123 |
Dänicke S et al. | Inactivation of deoxynivalenol-contaminated cereal grains with sodium metabisulfite: a review of procedures and toxicological aspects. | 2012 | Mycotoxin Res | pmid:23606192 |
Lohölter M et al. | Effects of the thermal environment on metabolism of deoxynivalenol and thermoregulatory response of sheep fed on corn silage grown at enriched atmospheric carbon dioxide and drought. | 2012 | Mycotoxin Res | pmid:23606193 |
Oldenburg E and Schittenhelm S | Effect of plant water deficit on the deoxynivalenol concentration in Fusarium-infected maize kernels. | 2012 | Mycotoxin Res | pmid:23606194 |
Halawa A et al. | Effects of deoxynivalenol and lipopolysaccharide on electrophysiological parameters in growing pigs. | 2012 | Mycotoxin Res | pmid:23606196 |
Dänicke S et al. | Humic substances failed to prevent the systemic absorption of deoxynivalenol (DON) and its adverse effects on piglets. | 2012 | Mycotoxin Res | pmid:23606197 |
Uegaki R et al. | Changes in the concentrations of fumonisin, deoxynivalenol and zearalenone in corn silage during ensilage. | 2013 | Anim. Sci. J. | pmid:23607902 |
Maresca M | From the gut to the brain: journey and pathophysiological effects of the food-associated trichothecene mycotoxin deoxynivalenol. | 2013 | Toxins (Basel) | pmid:23612752 |
Warth B et al. | New insights into the human metabolism of the Fusarium mycotoxins deoxynivalenol and zearalenone. | 2013 | Toxicol. Lett. | pmid:23623764 |
Awad W et al. | The toxicological impacts of the Fusarium mycotoxin, deoxynivalenol, in poultry flocks with special reference to immunotoxicity. | 2013 | Toxins (Basel) | pmid:23628787 |
Meneely J et al. | Rapid surface plasmon resonance immunoassay for the determination of deoxynivalenol in wheat, wheat products, and maize-based baby food. | 2010 | J. Agric. Food Chem. | pmid:23654230 |
Njumbe Ediage E et al. | Multimycotoxin analysis in urines to assess infant exposure: a case study in Cameroon. | 2013 | Environ Int | pmid:23669720 |
Flannery BM et al. | Deoxynivalenol-induced weight loss in the diet-induced obese mouse is reversible and PKR-independent. | 2013 | Toxicol. Lett. | pmid:23707852 |
Ngampongsa S et al. | Toxic effects of T-2 toxin and deoxynivalenol on the mitochondrial electron transport system of cardiomyocytes in rats. | 2013 | J Toxicol Sci | pmid:23719927 |
Alassane-Kpembi I et al. | New insights into mycotoxin mixtures: the toxicity of low doses of Type B trichothecenes on intestinal epithelial cells is synergistic. | 2013 | Toxicol. Appl. Pharmacol. | pmid:23735874 |
Schweiger W et al. | Transcriptomic characterization of two major Fusarium resistance quantitative trait loci (QTLs), Fhb1 and Qfhs.ifa-5A, identifies novel candidate genes. | 2013 | Mol. Plant Pathol. | pmid:23738863 |
Winter M et al. | Mechanisms regulating grain contamination with trichothecenes translocated from the stem base of wheat (Triticum aestivum) infected with Fusarium culmorum. | 2013 | Phytopathology | pmid:23758328 |
Linkmeyer A et al. | Assessment and introduction of quantitative resistance to Fusarium head blight in elite spring barley. | 2013 | Phytopathology | pmid:23777405 |
Sanders M et al. | Sampling of wheat dust and subsequent analysis of deoxynivalenol by LC-MS/MS. | 2013 | J. Agric. Food Chem. | pmid:23782015 |
pmid:23791694 | ||||
Kadota T et al. | Comparative study of deoxynivalenol, 3-acetyldeoxynivalenol, and 15-acetyldeoxynivalenol on intestinal transport and IL-8 secretion in the human cell line Caco-2. | 2013 | Toxicol In Vitro | pmid:23792671 |
Lei M et al. | In vitro investigation of individual and combined cytotoxic effects of aflatoxin B1 and other selected mycotoxins on the cell line porcine kidney 15. | 2013 | Exp. Toxicol. Pathol. | pmid:23809186 |
Pan X et al. | Early phosphoproteomic changes in the mouse spleen during deoxynivalenol-induced ribotoxic stress. | 2013 | Toxicol. Sci. | pmid:23811945 |
Strasser A et al. | Protective effects of antioxidants on deoxynivalenol-induced damage in murine lymphoma cells. | 2013 | Mycotoxin Res | pmid:23813191 |
Li D et al. | Gene expression profiling analysis of deoxynivalenol-induced inhibition of mouse thymic epithelial cell proliferation. | 2013 | Environ. Toxicol. Pharmacol. | pmid:23827195 |
Rempe I et al. | Effects of a Fusarium toxin-contaminated maize treated with sodium metabisulphite, methylamine and calcium hydroxide in diets for female piglets. | 2013 | Arch Anim Nutr | pmid:23859352 |
Ogiso M et al. | Survey of 7 trichothecenes in corn-derived feed and feed ingredients. | 2013 | Shokuhin Eiseigaku Zasshi | pmid:23863366 |
Weaver AC et al. | The use of feed additives to reduce the effects of aflatoxin and deoxynivalenol on pig growth, organ health and immune status during chronic exposure. | 2013 | Toxins (Basel) | pmid:23867763 |
Blandino M et al. | Nutritional and technological quality of bread enriched with an intermediated pearled wheat fraction. | 2013 | Food Chem | pmid:23870994 |
Dänicke S and Brezina U | Kinetics and metabolism of the Fusarium toxin deoxynivalenol in farm animals: consequences for diagnosis of exposure and intoxication and carry over. | 2013 | Food Chem. Toxicol. | pmid:23872131 |
Perkowski J et al. | Mycotoxins in cereal grain. Part 13. Deoxynivalenol and 3-acetyl-deoxynivalenol in wheat kernels and chaff with head fusariosis symptoms. | 1990 | Nahrung | pmid:2388686 |
van der Fels-Klerx HJ | Evaluation of performance of predictive models for deoxynivalenol in wheat. | 2014 | Risk Anal. | pmid:23901939 |
Sliková S et al. | Occurrence of deoxynivalenol in wheat in Slovakia during 2010 and 2011. | 2013 | Toxins (Basel) | pmid:23917334 |
Osselaere A et al. | Deoxynivalenol impairs hepatic and intestinal gene expression of selected oxidative stress, tight junction and inflammation proteins in broiler chickens, but addition of an adsorbing agent shifts the effects to the distal parts of the small intestine. | 2013 | PLoS ONE | pmid:23922676 |
Wu L et al. | Effects of dietary arginine and glutamine on alleviating the impairment induced by deoxynivalenol stress and immune relevant cytokines in growing pigs. | 2013 | PLoS ONE | pmid:23922725 |
Diamond M et al. | The fusarium mycotoxin deoxynivalenol can inhibit plant apoptosis-like programmed cell death. | 2013 | PLoS ONE | pmid:23922734 |
Abbas HK et al. | Cytotoxicity and phytotoxicity of trichothecene mycotoxins produced by Fusarium spp. | 2013 | Toxicon | pmid:23933195 |
Tutelyan VA et al. | A survey of the occurrence of deoxynivalenol in wheat from 1986-1988 harvests in the USSR. | 1990 Jul-Aug | Food Addit Contam | pmid:2394272 |
Van Nguyen T et al. | The ATF/CREB transcription factor Atf1 is essential for full virulence, deoxynivalenol production, and stress tolerance in the cereal pathogen Fusarium graminearum. | 2013 | Mol. Plant Microbe Interact. | pmid:23945004 |
Nossol C et al. | Deoxynivalenol affects the composition of the basement membrane proteins and influences en route the migration of CD16(+) cells into the intestinal epithelium. | 2013 | Mycotoxin Res | pmid:23949948 |
Hubert J et al. | The effect of Tyrophagus putrescentiae on Fusarium poae transmission and fungal community in stored barley in a laboratory experiment. | 2014 | Insect Sci. | pmid:23955921 |
He X et al. | Linkage mapping and identification of QTL affecting deoxynivalenol (DON) content (Fusarium resistance) in oats (Avena sativa L.). | 2013 | Theor. Appl. Genet. | pmid:23959525 |
Fredlund E et al. | Deoxynivalenol and other selected Fusarium toxins in Swedish oats--occurrence and correlation to specific Fusarium species. | 2013 | Int. J. Food Microbiol. | pmid:23962918 |
Lindblad M et al. | Deoxynivalenol and other selected Fusarium toxins in Swedish wheat--occurrence and correlation to specific Fusarium species. | 2013 | Int. J. Food Microbiol. | pmid:23962919 |
Schwartz HE et al. | Characterization of three deoxynivalenol sulfonates formed by reaction of deoxynivalenol with sulfur reagents. | 2013 | J. Agric. Food Chem. | pmid:23964860 |
Xiao H et al. | Effects of composite antimicrobial peptides in weanling piglets challenged with deoxynivalenol: I. Growth performance, immune function, and antioxidation capacity. | 2013 | J. Anim. Sci. | pmid:23965387 |
Xiao H et al. | Effects of composite antimicrobial peptides in weanling piglets challenged with deoxynivalenol: II. Intestinal morphology and function. | 2013 | J. Anim. Sci. | pmid:23965392 |
Ghareeb K et al. | Effects of feed contaminant deoxynivalenol on plasma cytokines and mRNA expression of immune genes in the intestine of broiler chickens. | 2013 | PLoS ONE | pmid:23977054 |
Shephard GS et al. | Multiple mycotoxin exposure determined by urinary biomarkers in rural subsistence farmers in the former Transkei, South Africa. | 2013 | Food Chem. Toxicol. | pmid:23985452 |
pmid:23994093 | ||||
Liu N et al. | The transcription cofactor FgSwi6 plays a role in growth and development, carbendazim sensitivity, cellulose utilization, lithium tolerance, deoxynivalenol production and virulence in the filamentous fungus Fusarium graminearum. | 2013 Sep-Oct | Fungal Genet. Biol. | pmid:23994322 |
MartÃnez G et al. | Penetration of fosfomycin into IPEC-J2 cells in the presence or absence of deoxynivalenol. | 2013 | PLoS ONE | pmid:24040387 |
Escobar J et al. | Occurrence and exposure assessment of Fusarium mycotoxins in maize germ, refined corn oil and margarine. | 2013 | Food Chem. Toxicol. | pmid:24056029 |
Van der Fels-Klerx HJ et al. | Impact of climate change effects on contamination of cereal grains with deoxynivalenol. | 2013 | PLoS ONE | pmid:24066059 |
Dänicke S et al. | Ascaridia galli infection affects pullets differently when feed is contaminated with the Fusarium toxin deoxynivalenol (DON). | 2013 | Vet. Parasitol. | pmid:24113465 |
Zheng Z et al. | Involvement of the anucleate primary sterigmata protein FgApsB in vegetative differentiation, asexual development, nuclear migration, and virulence in Fusarium graminearum. | 2013 | FEMS Microbiol. Lett. | pmid:24117691 |
Abia WA et al. | Bio-monitoring of mycotoxin exposure in Cameroon using a urinary multi-biomarker approach. | 2013 | Food Chem. Toxicol. | pmid:24128729 |
Malbrán I et al. | Toxigenic capacity and trichothecene production by Fusarium graminearum isolates from Argentina and their relationship with aggressiveness and fungal expansion in the wheat spike. | 2014 | Phytopathology | pmid:24168045 |
Ogiso M et al. | Investigation of the suitability of immunochemical-based test kits for quantitative analysis of deoxynivalenol in corn-derived feed and feed ingredients. | 2013 | Shokuhin Eiseigaku Zasshi | pmid:24190288 |
MankeviÄienÄ— A et al. | Occurrence of mycotoxins in spelt and common wheat grain and their products. | 2014 | Food Addit Contam Part A Chem Anal Control Expo Risk Assess | pmid:24199659 |
Devreese M et al. | The effects of feed-borne Fusarium mycotoxins and glucomannan in turkey poults based on specific and non-specific parameters. | 2014 | Food Chem. Toxicol. | pmid:24200858 |
Wang Y et al. | Development and application of a method for the analysis of 9 mycotoxins in maize by HPLC-MS/MS. | 2013 | J. Food Sci. | pmid:24245893 |
Schmeits PC et al. | DON shares a similar mode of action as the ribotoxic stress inducer anisomycin while TBTO shares ER stress patterns with the ER stress inducer thapsigargin based on comparative gene expression profiling in Jurkat T cells. | 2014 | Toxicol. Lett. | pmid:24247028 |