Vomitoxin is a lipid of Prenol Lipids (PR) class. Vomitoxin is associated with abnormalities such as Infection and Gastroenteritis. The involved functions are known as mRNA Expression, Inflammation, Transcription, Genetic, Protein Biosynthesis and Adverse effects. Vomitoxin often locates in Lymphoid Tissue, Immune system, Bone Marrow and Plasma membrane. The associated genes with Vomitoxin are IMPACT gene, HIST1H1C gene and RBM39 gene. The related experimental models are Mouse Model.
To understand associated biological information of Vomitoxin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Vomitoxin is suspected in Infection, Gastroenteritis and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Vomitoxin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
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Mouse Model are used in the study 'Dietary fish oil suppresses experimental immunoglobulin a nephropathy in mice.' (Pestka JJ et al., 2002).
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Authors | Title | Published | Journal | PubMed Link |
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Huang XH et al. | [Carcinogenic effects of sterigmatocystin and deoxynivalenol in NIH mice]. | 2004 | Zhonghua Zhong Liu Za Zhi | pmid:15733384 |
Lu G et al. | [Studies on deoxynivalenol contamination in grain and its products in Anhui Province]. | 1994 | Zhonghua Yu Fang Yi Xue Za Zhi | pmid:8082456 |
Hou HF et al. | [The cytotoxic effect and injury mechanism of deoxynivalenol on articular chondrocytes in human embryo]. | 2011 | Zhonghua Yu Fang Yi Xue Za Zhi | pmid:22041568 |
Peng SQ and Yang JS | [Effect of deoxynivalenol on action potentials of cultured cardiomyocytes and the protective effects of selenium]. | 2003 | Zhonghua Yu Fang Yi Xue Za Zhi | pmid:14703497 |
Li FQ et al. | [Natural occurrence of masked deoxynivalenol and multi-mycotoxins in cereals from China harvested in 2007 and 2008]. | 2011 | Zhonghua Yu Fang Yi Xue Za Zhi | pmid:21418821 |
Guo HW | [Gas chromatography with electron capture detector for determining DON and NIV in scabby wheat]. | 1989 | Zhonghua Yu Fang Yi Xue Za Zhi | pmid:2625066 |
Wang W et al. | [Probabilistic assessment of dietary exposure to both deoxynivalenol and zearalenone from cereal-based products in Chinese populations]. | 2015 | Zhonghua Yu Fang Yi Xue Za Zhi | pmid:26268865 |
Zhou BJ et al. | [Effects of vitamin C on apoptosis and proliferation inhibition of human peripheral blood mononuclear cells induced by deoxynivalenol in vitro]. | 2006 | Zhonghua Yu Fang Yi Xue Za Zhi | pmid:17166419 |
Zhou BJ et al. | [Effects of vitamin C on the inhibition of human leucocyte antigen class I (HLA-I) expression of human peripheral blood mononuclear cells induced by deoxynivalenol in vitro]. | 2006 | Zhonghua Yu Fang Yi Xue Za Zhi | pmid:17166420 |
Usleber E et al. | Studies on the application of enzyme immunoassays for the Fusarium mycotoxins deoxynivalenol, 3-acetyldeoxynivalenol, and zearalenone. | 1992 | Zentralblatt Veterinarmedizin Reihe B | pmid:1462727 |
Bergsjø B et al. | Effects of diets with graded levels of deoxynivalenol on performance in growing pigs. | 1992 | Zentralbl Veterinarmed A | pmid:1492508 |
Marpegan MR et al. | Feed refusal of pigs caused by Fusarium mycotoxins in Argentina. | 1988 | Zentralbl Veterinarmed A | pmid:3142186 |
Rizzo AF et al. | Protective effect of antioxidants against free radical-mediated lipid peroxidation induced by DON or T-2 toxin. | 1994 | Zentralbl Veterinarmed A | pmid:8091893 |
Overnes G et al. | Effects of diets with graded levels of naturally deoxynivalenol-contaminated oats on immune response in growing pigs. | 1997 | Zentralbl Veterinarmed A | pmid:9465774 |
Ali-Vehmas T et al. | Measurement of antibacterial activities of T-2 toxin, deoxynivalenol, ochratoxin A, aflatoxin B1 and fumonisin B1 using microtitration tray-based turbidimetric techniques. | 1998 | Zentralbl Veterinarmed A | pmid:9838857 |
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Blaas W et al. | [Determination of deoxynivalenol and nivalenol in cereals at the microgram/kilogram range]. | 1984 | Z Lebensm Unters Forsch | pmid:6485556 |
Mulders EJ and van Impelen-Peek HA | Gas chromatographic determination of deoxynivalenol in cereals. | 1986 | Z Lebensm Unters Forsch | pmid:3811598 |
Steinmeyer S et al. | [Gas chromatographic study of deoxynivalenol and nivalenol in cereals following derivatization with heptafluorobutyrates]. | 1985 | Z Lebensm Unters Forsch | pmid:4050128 |
Zhu FX et al. | [Enhancing effect of deoxynivalenol-mediated GRP78 down-regulation on heavy chain secretion and bioactivity of two-chain FVIII gene co-transfected cells]. | 2011 | Yao Xue Xue Bao | pmid:22375418 |
Li YH et al. | [The inhibitory effect of deoxynivalenol on TAP-1 expression in human peripheral blood mononuclear cells in vitro]. | 2005 | Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi | pmid:15766417 |
Worrell NR et al. | The role of gut micro-organisms in the metabolism of deoxynivalenol administered to rats. | 1989 | Xenobiotica | pmid:2756716 |
Islam R et al. | Aerobic and anaerobic de-epoxydation of mycotoxin deoxynivalenol by bacteria originating from agricultural soil. | 2012 | World J. Microbiol. Biotechnol. | pmid:22806774 |
Wang H et al. | [Effects of deoxynivalenol on proliferation and tumor necrosis factor-alpha secretion of human peripheral blood mononuclear cells in vitro]. | 2000 | Wei Sheng Yan Jiu | pmid:12520964 |
Lin X et al. | [Development of in vitro digestion model for assessing the bioaccessibility of deoxynivalenol derived from foods]. | 2012 | Wei Sheng Yan Jiu | pmid:22443053 |
Liu J et al. | [Effects of deoxynivalenol on apoptosis of human gastric carcinoma cell line SGC-7901, BGC-823 in vitro]. | 2009 | Wei Sheng Yan Jiu | pmid:19689068 |
Wang H et al. | [Effect of deoxynivalenol and aflatoxin G1 on apoptosis of human blood lymphocytes in vitro]. | 1999 | Wei Sheng Yan Jiu | pmid:11938994 |
Yu C et al. | [Study advance on formation, transformation and detection of masked deoxynivalenol]. | 2009 | Wei Sheng Yan Jiu | pmid:19408673 |
Ji F et al. | [Development of the monoclonal antibody to deoxynivalenol]. | 2008 | Wei Sheng Wu Xue Bao | pmid:18837372 |
Wettstein FE and Bucheli TD | Poor elimination rates in waste water treatment plants lead to continuous emission of deoxynivalenol into the aquatic environment. | 2010 | Water Res. | pmid:20547404 |
Sergeev IN et al. | [The effect of the trichothecene mycotoxin deoxynivalenol (vomitoxin) on calcium homeostasis, vitamin D metabolism and receptors in rats]. | 1990 Sep-Oct | Vopr. Med. Khim. | pmid:2174586 |
Zakharova LP et al. | [Grain contamination by deoxynivalenol in Russia]. | 1994 | Vopr Pitan | pmid:7975431 |
Tutel'ian VA et al. | [A method of determining the levels of deoxynivalenol (vomitoxin) and its metabolites]. | 1991 Sep-Oct | Vopr Pitan | pmid:1796578 |
Sobolev VS et al. | [The contamination of the 1986-1988 wheat harvests with deoxynivalenol (vomitoxin)]. | 1990 Jan-Feb | Vopr Pitan | pmid:2140639 |
Obol'skiÄ OL et al. | [Effect of dietary selenium on the activity of UDP-glucuronosyltransferases and metabolism of mycotoxin deoxynivalenol in rats]. | 1998 | Vopr Pitan | pmid:9825468 |
Severino L et al. | Immune effects of four Fusarium-toxins (FB1, ZEA, NIV, DON) on the proliferation of Jurkat cells and porcine lymphocytes: in vitro study. | 2008 | Vet. Res. Commun. | pmid:18683067 |
Bergsjø B et al. | The effects of naturally deoxynivalenol-contaminated oats on the clinical condition, blood parameters, performance and carcass composition of growing pigs. | 1993 | Vet. Res. Commun. | pmid:8146954 |
Tognon G et al. | Implementation of the electronic nose for the identification of mycotoxins in durum wheat (Triticum durum). | 2005 | Vet. Res. Commun. | pmid:16245002 |
Ferrari L et al. | Cellular immune response and immunotoxicity induced by DON (deoxynivalenol) in piglets. | 2009 | Vet. Res. Commun. | pmid:19578957 |
Gu MJ et al. | Barrier protection via Toll-like receptor 2 signaling in porcine intestinal epithelial cells damaged by deoxynivalnol. | 2016 | Vet. Res. | pmid:26857454 |
Vandenbroucke V et al. | The mycotoxin deoxynivalenol promotes uptake of Salmonella Typhimurium in porcine macrophages, associated with ERK1/2 induced cytoskeleton reorganization. | 2009 Nov-Dec | Vet. Res. | pmid:19674540 |
Jakovac-Strajn B et al. | Effects of a deoxynivalenol-contaminated diet on the reproductive performance and immunoglobulin concentrations in pigs. | 2009 | Vet. Rec. | pmid:20008344 |
Dänicke S et al. | Ascaridia galli infection affects pullets differently when feed is contaminated with the Fusarium toxin deoxynivalenol (DON). | 2013 | Vet. Parasitol. | pmid:24113465 |
Awad WA et al. | Mechanisms underlying the inhibitory effect of the feed contaminant deoxynivalenol on glucose absorption in broiler chickens. | 2014 | Vet. J. | pmid:25011710 |
Tiemann U et al. | Changes in the spleen and liver of pregnant sows and full-term piglets after feeding diets naturally contaminated with deoxynivalenol and zearalenone. | 2008 | Vet. J. | pmid:17434324 |
Moss MO | Fusarial toxins: are they a cause for concern? | 2003 | Vet. J. | pmid:12672361 |
Mthiyane DM and Mhlanga BS | The nutritive value of marula (Sclerocarya birrea) seed cake for broiler chickens: nutritional composition, performance, carcass characteristics and oxidative and mycotoxin status. | 2017 | Trop Anim Health Prod | pmid:28332071 |
Giménez I et al. | Effects of bread making and wheat germ addition on the natural deoxynivalenol content in bread. | 2014 | Toxins (Basel) | pmid:24451845 |
Pietsch C et al. | Occurrence of deoxynivalenol and zearalenone in commercial fish feed: an initial study. | 2013 | Toxins (Basel) | pmid:23325300 |
Awad W et al. | The toxicological impacts of the Fusarium mycotoxin, deoxynivalenol, in poultry flocks with special reference to immunotoxicity. | 2013 | Toxins (Basel) | pmid:23628787 |