Vomitoxin is a lipid of Prenol Lipids (PR) class. Vomitoxin is associated with abnormalities such as Infection and Gastroenteritis. The involved functions are known as mRNA Expression, Inflammation, Transcription, Genetic, Protein Biosynthesis and Adverse effects. Vomitoxin often locates in Lymphoid Tissue, Immune system, Bone Marrow and Plasma membrane. The associated genes with Vomitoxin are IMPACT gene, HIST1H1C gene and RBM39 gene. The related experimental models are Mouse Model.
To understand associated biological information of Vomitoxin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Vomitoxin is suspected in Infection, Gastroenteritis and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Vomitoxin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Dietary fish oil suppresses experimental immunoglobulin a nephropathy in mice.' (Pestka JJ et al., 2002).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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De Baere S et al. | Quantitative determination of T-2 toxin, HT-2 toxin, deoxynivalenol and deepoxy-deoxynivalenol in animal body fluids using LC-MS/MS detection. | 2011 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:21767999 |
Razzazi-Fazeli E et al. | Simultaneous determination of major B-trichothecenes and the de-epoxy-metabolite of deoxynivalenol in pig urine and maize using high-performance liquid chromatography-mass spectrometry. | 2003 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:14552813 |
Lattanzio VM et al. | LC-MS/MS characterization of the urinary excretion profile of the mycotoxin deoxynivalenol in human and rat. | 2011 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:21367675 |
Klinglmayr C et al. | Determination of deoxynivalenol in organic and conventional food and feed by sol-gel immunoaffinity chromatography and HPLC-UV detection. | 2010 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:19736050 |
Charmley E et al. | Influence of level of deoxynivalenol in the diet of dairy cows on feed intake, milk production, and its composition. | 1993 | J. Dairy Sci. | pmid:8270701 |
Schmidt P et al. | Concentration of mycotoxins and chemical composition of corn silage: a farm survey using infrared thermography. | 2015 | J. Dairy Sci. | pmid:26162792 |
Côté LM et al. | Excretion of deoxynivalenol and its metabolite in milk, urine, and feces of lactating dairy cows. | 1986 | J. Dairy Sci. | pmid:3782592 |
Trenholm HL et al. | Ingestion of vomitoxin (deoxynivalenol)-contaminated wheat by nonlactating dairy cows. | 1985 | J. Dairy Sci. | pmid:3998233 |
Krout-Greenberg ND et al. | Preliminary study to assess mycotoxin concentrations in whole corn in the California feed supply. | 2013 | J. Dairy Sci. | pmid:23462178 |
Pettersson H and Kiessling KH | Mycotoxins in Swedish grains and mixed feeds. | 1992 Mar-Apr | J. Environ. Pathol. Toxicol. Oncol. | pmid:1573563 |
Naef A et al. | Impact of transgenic Bt maize residues on the mycotoxigenic plant pathogen Fusarium graminearum and the biocontrol agent Trichoderma atroviride. | 2006 Jul-Aug | J. Environ. Qual. | pmid:16738384 |
Masuda D et al. | Phytotoxic effects of trichothecenes on the growth and morphology of Arabidopsis thaliana. | 2007 | J. Exp. Bot. | pmid:17426057 |
Shin S et al. | Transgenic Arabidopsis thaliana expressing a barley UDP-glucosyltransferase exhibit resistance to the mycotoxin deoxynivalenol. | 2012 | J. Exp. Bot. | pmid:22922639 |
Walter S et al. | A wheat ABC transporter contributes to both grain formation and mycotoxin tolerance. | 2015 | J. Exp. Bot. | pmid:25732534 |
Choi HJ et al. | Postharvest strategies for deoxynivalenol and zearalenone reduction in stored adlay (Coix lachryma-jobi L.) grains. | 2014 | J. Food Prot. | pmid:24674439 |
Ngundi MM et al. | Multiplexed detection of mycotoxins in foods with a regenerable array. | 2006 | J. Food Prot. | pmid:17186679 |
Dombrink-Kurtzman MA et al. | Determination of deoxynivalenol in infant cereal by immunoaffinity column cleanup and high-pressure liquid chromatography-UV detection. | 2010 | J. Food Prot. | pmid:20537262 |
Accerbi M et al. | Utilization of highly deoxynivalenol-contaminated wheat via extrusion processing. | 1999 | J. Food Prot. | pmid:10606158 |
Sasanya JJ et al. | Analysis of deoxynivalenol, masked deoxynivalenol, and Fusarium graminearum pigment in wheat samples, using liquid chromatography-UV-mass spectrometry. | 2008 | J. Food Prot. | pmid:18592747 |
Zhou B et al. | Occurrence of bound deoxynivalenol in Fusarium head blight-infected barley (Hordeum vulgare L.) and malt as determined by solvolysis with trifluoroacetic acid. | 2008 | J. Food Prot. | pmid:18592758 |
Lee T et al. | Occurrence of Fusarium mycotoxins in rice and its milling by-products in Korea. | 2011 | J. Food Prot. | pmid:21740720 |
Pralatnet S et al. | Survey of Deoxynivalenol and Aflatoxin B1 in Instant Noodles and Bread Consumed in Thailand by Using Liquid Chromatography-Tandem Mass Spectrometry. | 2016 | J. Food Prot. | pmid:27357050 |
Poapolathep A et al. | Detection of deoxynivalenol contamination in wheat products in Thailand. | 2008 | J. Food Prot. | pmid:18810882 |
Jajić I et al. | Incidence of deoxynivalenol in Serbian wheat and barley. | 2014 | J. Food Prot. | pmid:24780345 |
Dodd JG et al. | Effect of ozone treatment on the safety and quality of malting barley. | 2011 | J. Food Prot. | pmid:22186055 |
Manthey FA et al. | Microbial loads, mycotoxins, and quality of durum wheat from the 2001 harvest of the northern plains region of the United States. | 2004 | J. Food Prot. | pmid:15083730 |
Yoshinari T et al. | Development of a purification method for simultaneous determination of deoxynivalenol and its acetylated and glycosylated derivatives in corn grits and corn flour by liquid chromatography-tandem mass spectrometry. | 2012 | J. Food Prot. | pmid:22980025 |
Thammawong M et al. | Distribution of deoxynivalenol and nivalenol in milling fractions from fusarium-infected Japanese wheat cultivars. | 2010 | J. Food Prot. | pmid:21067669 |
van der Fels-Klerx HJ et al. | Modeling deoxynivalenol contamination of wheat in northwestern Europe for climate change assessments. | 2012 | J. Food Prot. | pmid:22691478 |
Hart LP et al. | Comparison of gas chromatography-electron capture and enzyme-linked immunosorbent assay for deoxynivalenol in milled fractions of naturally contaminated wheat. | 1998 | J. Food Prot. | pmid:9874353 |
Beattie S et al. | The effect of grain storage conditions on the viability of Fusarium and deoxynivalenol production in infested malting barley. | 1998 | J. Food Prot. | pmid:9708261 |
Wolf CE and Bullerman LB | Heat and pH alter the concentration of deoxynivalenol in an aqueous environment. | 1998 | J. Food Prot. | pmid:9708313 |
Galvano F et al. | Activated carbons: in vitro affinity for ochratoxin A and deoxynivalenol and relation of adsorption ability to physicochemical parameters. | 1998 | J. Food Prot. | pmid:9709212 |
Wolf-Hall CE et al. | Stability of deoxynivalenol in heat-treated foods. | 1999 | J. Food Prot. | pmid:10456755 |
Martins ML and Martins HM | Determination of deoxynivalenol in wheat-based breakfast cereals marketed in Portugal. | 2001 | J. Food Prot. | pmid:11726173 |
Yoshinari T et al. | Occurrence of four Fusarium mycotoxins, deoxynivalenol, zearalenone, T-2 toxin, and HT-2 toxin, in wheat, barley, and Japanese retail food. | 2014 | J. Food Prot. | pmid:25364928 |
Lippolis V et al. | Optimization of a fluorescence polarization immunoassay for rapid quantification of deoxynivalenol in durum wheat-based products. | 2006 | J. Food Prot. | pmid:17133816 |
Franz E et al. | Prediction of deoxynivalenol content in Dutch winter wheat. | 2009 | J. Food Prot. | pmid:19833041 |
Mbandi E and Pestka JJ | Deoxynivalenol and satratoxin G potentiate proinflammatory cytokine and macrophage inhibitory protein 2 induction by Listeria and Salmonella in the macrophage. | 2006 | J. Food Prot. | pmid:16786854 |
Gallo G et al. | Mycotoxins in durum wheat grain: hygienic-health quality of sicilian production. | 2008 | J. Food Sci. | pmid:18460144 |
Wang Y et al. | Development and application of a method for the analysis of 9 mycotoxins in maize by HPLC-MS/MS. | 2013 | J. Food Sci. | pmid:24245893 |
Vegi A and Wolf-Hall CE | Multiplex real-time PCR method for detection and quantification of mycotoxigenic fungi belonging to three different genera. | 2013 | J. Food Sci. | pmid:23278665 |
Lee HJ and Ryu D | Advances in Mycotoxin Research: Public Health Perspectives. | 2015 | J. Food Sci. | pmid:26565730 |
Kim KY et al. | Development of a simultaneous lateral flow strip test for the rapid and simple detection of deoxynivalenol and zearalenone. | 2014 | J. Food Sci. | pmid:25224778 |
Türker L and Gümüş S | A theoretical study on vomitoxin and its tautomers. | 2009 | J. Hazard. Mater. | pmid:18657904 |
Park SH et al. | Repression of peroxisome proliferator-activated receptor gamma by mucosal ribotoxic insult-activated CCAAT/enhancer-binding protein homologous protein. | 2010 | J. Immunol. | pmid:20889551 |
Czeh A et al. | A flow cytometry based competitive fluorescent microsphere immunoassay (CFIA) system for detecting up to six mycotoxins. | 2012 | J. Immunol. Methods | pmid:22841575 |
Vujanovic V et al. | Heat- and cold-shock responses in Fusarium graminearum 3 acetyl- and 15 acetyl-deoxynivalenol chemotypes. | 2012 | J. Microbiol. | pmid:22367943 |
Abolmaali S et al. | Engineered bakers yeast as a sensitive bioassay indicator organism for the trichothecene toxin deoxynivalenol. | 2008 | J. Microbiol. Methods | pmid:18243380 |
Fredlund E et al. | Method evaluation of Fusarium DNA extraction from mycelia and wheat for down-stream real-time PCR quantification and correlation to mycotoxin levels. | 2008 | J. Microbiol. Methods | pmid:18304664 |
Burrows EP and Szafraniec LL | Hypochlorite-promoted transformations of trichothecenes, 3. Deoxynivalenol. | 1987 Nov-Dec | J. Nat. Prod. | pmid:2832543 |
Jia Q et al. | Docosahexaenoic acid attenuates mycotoxin-induced immunoglobulin a nephropathy, interleukin-6 transcription, and mitogen-activated protein kinase phosphorylation in mice. | 2004 | J. Nutr. | pmid:15570035 |
Jia Q et al. | Docosahexaenoic acid and eicosapentaenoic acid, but not alpha-linolenic acid, suppress deoxynivalenol-induced experimental IgA nephropathy in mice. | 2004 | J. Nutr. | pmid:15173396 |
Akbari P et al. | Galacto-oligosaccharides Protect the Intestinal Barrier by Maintaining the Tight Junction Network and Modulating the Inflammatory Responses after a Challenge with the Mycotoxin Deoxynivalenol in Human Caco-2 Cell Monolayers and B6C3F1 Mice. | 2015 | J. Nutr. | pmid:26019243 |
Jia Q et al. | Docosahexaenoic acid consumption inhibits deoxynivalenol-induced CREB/ATF1 activation and IL-6 gene transcription in mouse macrophages. | 2006 | J. Nutr. | pmid:16424113 |
Pinton P et al. | Deoxynivalenol impairs porcine intestinal barrier function and decreases the protein expression of claudin-4 through a mitogen-activated protein kinase-dependent mechanism. | 2010 | J. Nutr. | pmid:20861219 |
Pestka JJ et al. | Dietary fish oil suppresses experimental immunoglobulin a nephropathy in mice. | 2002 | J. Nutr. | pmid:11823588 |
Maresca M et al. | The mycotoxin deoxynivalenol affects nutrient absorption in human intestinal epithelial cells. | 2002 | J. Nutr. | pmid:12221236 |
Moon Y and Pestka JJ | Deoxynivalenol-induced mitogen-activated protein kinase phosphorylation and IL-6 expression in mice suppressed by fish oil. | 2003 | J. Nutr. Biochem. | pmid:14690764 |
Shi Y and Pestka JJ | Attenuation of mycotoxin-induced IgA nephropathy by eicosapentaenoic acid in the mouse: dose response and relation to IL-6 expression. | 2006 | J. Nutr. Biochem. | pmid:16524712 |
Shi Y and Pestka JJ | Mechanisms for suppression of interleukin-6 expression in peritoneal macrophages from docosahexaenoic acid-fed mice. | 2009 | J. Nutr. Biochem. | pmid:18602807 |
Kinser S et al. | Truncated deoxynivalenol-induced splenic immediate early gene response in mice consuming (n-3) polyunsaturated fatty acids. | 2005 | J. Nutr. Biochem. | pmid:15681167 |
Fioramonti J et al. | The mycotoxin, deoxynivalenol, delays gastric emptying through serotonin-3 receptors in rodents. | 1993 | J. Pharmacol. Exp. Ther. | pmid:8371135 |
Mudili V et al. | Mould incidence and mycotoxin contamination in freshly harvested maize kernels originated from India. | 2014 | J. Sci. Food Agric. | pmid:24609945 |
Garcia D et al. | Impact of cycling temperatures on Fusarium verticillioides and Fusarium graminearum growth and mycotoxins production in soybean. | 2012 | J. Sci. Food Agric. | pmid:22555960 |
Juodeikiene G et al. | Benefits of β-xylanase for wheat biomass conversion to bioethanol. | 2012 | J. Sci. Food Agric. | pmid:21744360 |
Torelli E et al. | The influence of local factors on the prediction of fumonisin contamination in maize. | 2012 | J. Sci. Food Agric. | pmid:22228027 |
Tran ST et al. | A survey of free and conjugated deoxynivalenol in the 2008 corn crop in Ontario, Canada. | 2012 | J. Sci. Food Agric. | pmid:21997524 |
Gilbert J et al. | A survey of the occurrence of the trichothecene mycotoxin deoxynivalenol (vomitoxin) in UK grown barley and in imported maize by combined gas chromatography-mass spectrometry. | 1983 | J. Sci. Food Agric. | pmid:6843094 |
Qiu J et al. | Effect of preceding crop on Fusarium species and mycotoxin contamination of wheat grains. | 2016 | J. Sci. Food Agric. | pmid:26867679 |
Zhang J et al. | Simultaneous detection of deoxynivalenol and zearalenone by dual-label time-resolved fluorescence immunoassay. | 2011 | J. Sci. Food Agric. | pmid:20945513 |
Ok HE et al. | Determination of deoxynivalenol in cereal-based foods and estimation of dietary exposure. | 2009 | J. Toxicol. Environ. Health Part A | pmid:20077214 |
Liu J et al. | Regulation of IL-8 promoter activity by verrucarin A in human monocytic THP-1 cells. | 2014 | J. Toxicol. Environ. Health Part A | pmid:25119735 |
Kinser S et al. | Gene expression profiling in spleens of deoxynivalenol-exposed mice: immediate early genes as primary targets. | 2004 | J. Toxicol. Environ. Health Part A | pmid:15371230 |
Drochner W et al. | Serum IgA-promoting effects induced by feed loads containing isolated deoxynivalenol (DON) in growing piglets. | 2004 | J. Toxicol. Environ. Health Part A | pmid:15205033 |
Amuzie CJ et al. | Effects of deoxynivalenol consumption on body weight and adiposity in the diet-induced obese mouse. | 2011 | J. Toxicol. Environ. Health Part A | pmid:21432715 |
Lee MG et al. | Effects of satratoxins and other macrocyclic trichothecenes on IL-2 production and viability of EL-4 thymoma cells. | 1999 | J. Toxicol. Environ. Health Part A | pmid:10494915 |
Zhou HR et al. | Amplified proinflammatory cytokine expression and toxicity in mice coexposed to lipopolysaccharide and the trichothecene vomitoxin (deoxynivalenol). | 1999 | J. Toxicol. Environ. Health Part A | pmid:10344227 |
Sugita-Konishi Y and Pestka JJ | Differential upregulation of TNF-alpha, IL-6, and IL-8 production by deoxynivalenol (vomitoxin) and other 8-ketotrichothecenes in a human macrophage model. | 2001 | J. Toxicol. Environ. Health Part A | pmid:11766169 |
Wong SS et al. | Effects of vomitoxin (deoxynivalenol) on the binding of transcription factors AP-1, NF-kappaB, and NF-IL6 in raw 264.7 macrophage cells. | 2002 | J. Toxicol. Environ. Health Part A | pmid:12167214 |
Osweiler GD et al. | Relationship of mycotoxins to swine reproductive failure. | 1990 | J. Vet. Diagn. Invest. | pmid:2151029 |
Johnson PJ et al. | Effect of feeding deoxynivalenol (vomitoxin)-contaminated barley to horses. | 1997 | J. Vet. Diagn. Invest. | pmid:9211250 |
Wada K et al. | Effects of mycotoxins on chemiluminescent response and cytokine mRNA expression of bovine neutrophils. | 2010 | J. Vet. Med. Sci. | pmid:20622479 |
Pralatnet S et al. | The fate and tissue disposition of deoxynivalenol in broiler chickens. | 2015 | J. Vet. Med. Sci. | pmid:25843039 |
Murata H et al. | Reduction of deoxynivalenol contaminating corn silage by short-term ultraviolet irradiation: a pilot study. | 2011 | J. Vet. Med. Sci. | pmid:21467760 |
Mikami O et al. | The effects of acute exposure to deoxynivalenol on some inflammatory parameters in miniature pigs. | 2011 | J. Vet. Med. Sci. | pmid:21224530 |
Takayama H et al. | Suppressive effect of deoxynivalenol, a Fusarium mycotoxin, on bovine and porcine neutrophil chemiluminescence: an in vitro study. | 2005 | J. Vet. Med. Sci. | pmid:15942140 |
Poapolathep A et al. | The effect of naringenin on the fate and disposition of deoxynivalenol in piglets. | 2010 | J. Vet. Med. Sci. | pmid:20467205 |
Mikami O et al. | Induction of apoptotic lesions in liver and lymphoid tissues and modulation of cytokine mRNA expression by acute exposure to deoxynivalenol in piglets. | 2010 | J. Vet. Sci. | pmid:20458150 |
Kim EJ et al. | Plasma haptoglobin and immunoglobulins as diagnostic indicators of deoxynivalenol intoxication. | 2008 | J. Vet. Sci. | pmid:18716445 |
Lee HM et al. | Development of a monoclonal antibody against deoxynivalenol for magnetic nanoparticle-based extraction and an enzyme-linked immunosorbent assay. | 2013 | J. Vet. Sci. | pmid:23388439 |
Chen F et al. | The combination of deoxynivalenol and zearalenone at permitted feed concentrations causes serious physiological effects in young pigs. | 2008 | J. Vet. Sci. | pmid:18296887 |
Boston S et al. | Consumption of deoxynivalenol-contaminated wheat by mallard ducks under experimental conditions. | 1996 | J. Wildl. Dis. | pmid:8627931 |
Etzel RA | Mycotoxins. | 2002 Jan 23-30 | JAMA | pmid:11798344 |
León-S FE et al. | Mycotoxins in myelopathies of man. | 1996 | Lancet | pmid:8855894 |
Hope R et al. | Comparison of environmental profiles for growth and deoxynivalenol production by Fusarium culmorum and F. graminearum on wheat grain. | 2005 | Lett. Appl. Microbiol. | pmid:15752221 |
Schnerr H et al. | Correlation between DNA of trichothecene-producing Fusarium species and deoxynivalenol concentrations in wheat-samples. | 2002 | Lett. Appl. Microbiol. | pmid:12100586 |
Hope R and Magan N | Two-dimensional environmental profiles of growth, deoxynivalenol and nivalenol production by Fusarium culmorum on a wheat-based substrate. | 2003 | Lett. Appl. Microbiol. | pmid:12803560 |
Cazzaniga D et al. | Mycotoxins inactivation by extrusion cooking of corn flour. | 2001 | Lett. Appl. Microbiol. | pmid:11472523 |
Payros D et al. | The Food Contaminant Deoxynivalenol Exacerbates the Genotoxicity of Gut Microbiota. | 2017 | MBio | pmid:28292979 |