Vomitoxin
Vomitoxin is a lipid of Prenol Lipids (PR) class. Vomitoxin is associated with abnormalities such as Infection and Gastroenteritis. The involved functions are known as mRNA Expression, Inflammation, Transcription, Genetic, Protein Biosynthesis and Adverse effects. Vomitoxin often locates in Lymphoid Tissue, Immune system, Bone Marrow and Plasma membrane. The associated genes with Vomitoxin are IMPACT gene, HIST1H1C gene and RBM39 gene. The related experimental models are Mouse Model.
Cross Reference
Introduction
To understand associated biological information of Vomitoxin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Vomitoxin?
Vomitoxin is suspected in Infection, Gastroenteritis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Vomitoxin
PubChem Associated disorders and diseases
What pathways are associated with Vomitoxin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Vomitoxin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Vomitoxin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Vomitoxin?
There are no associated biomedical information in the current reference collection.
What genes are associated with Vomitoxin?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Vomitoxin?
Mouse Model
Mouse Model are used in the study 'Dietary fish oil suppresses experimental immunoglobulin a nephropathy in mice.' (Pestka JJ et al., 2002).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with Vomitoxin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Meky FA et al. | Development of a urinary biomarker of human exposure to deoxynivalenol. | 2003 | Food Chem. Toxicol. | pmid:12480302 |
| Malovrh T and Jakovac-Strajn B | Feed contaminated with Fusarium toxins alter lymphocyte proliferation and apoptosis in primiparous sows during the perinatal period. | 2010 | Food Chem. Toxicol. | pmid:20654678 |
| Devreese M et al. | The effects of feed-borne Fusarium mycotoxins and glucomannan in turkey poults based on specific and non-specific parameters. | 2014 | Food Chem. Toxicol. | pmid:24200858 |
| Chan PK and Gentry PA | Inhibition of bovine platelet function by T-2 toxin, HT-2 toxin, diacetoxyscirpenol and deoxynivalenol. | 1984 | Food Chem. Toxicol. | pmid:6540739 |
| Pestka JJ and Zhou HR | Interleukin-6-deficient mice refractory to IgA dysregulation but not anorexia induction by vomitoxin (deoxynivalenol) ingestion. | 2000 | Food Chem. Toxicol. | pmid:10942317 |
| Zhou H et al. | Individual and combined effects of Aflatoxin B, Deoxynivalenol and Zearalenone on HepG2 and RAW 264.7 cell lines. | 2017 | Food Chem. Toxicol. | pmid:28223122 |
| Kalaiselvi P et al. | Cytoprotective effect of epigallocatechin-3-gallate against deoxynivalenol-induced toxicity through anti-oxidative and anti-inflammatory mechanisms in HT-29 cells. | 2013 | Food Chem. Toxicol. | pmid:23410590 |
| Bensassi F et al. | Involvement of mitochondria-mediated apoptosis in deoxynivalenol cytotoxicity. | 2012 | Food Chem. Toxicol. | pmid:22281158 |
| Pestka JJ et al. | Suppression of immune response in the B6C3F1 mouse after dietary exposure to the Fusarium mycotoxins deoxynivalenol (vomitoxin) and zearalenone. | 1987 | Food Chem. Toxicol. | pmid:2953660 |
| Morrissey RE et al. | Subchronic toxicity of vomitoxin in Sprague-Dawley rats. | 1985 | Food Chem. Toxicol. | pmid:2934304 |
| Forsell JH et al. | Effects of 8-week exposure of the B6C3F1 mouse to dietary deoxynivalenol (vomitoxin) and zearalenone. | 1986 | Food Chem. Toxicol. | pmid:2937701 |
| Nielsen JK et al. | Deoxynivalenol transport across the human placental barrier. | 2011 | Food Chem. Toxicol. | pmid:21620924 |
| van der Fels-Klerx HJ et al. | A framework to determine the effectiveness of dietary exposure mitigation to chemical contaminants. | 2014 | Food Chem. Toxicol. | pmid:25445762 |
| Cetin Y and Bullerman LB | Cytotoxicity of Fusarium mycotoxins to mammalian cell cultures as determined by the MTT bioassay. | 2005 | Food Chem. Toxicol. | pmid:15778016 |
| Vidal A et al. | Determination of aflatoxins, deoxynivalenol, ochratoxin A and zearalenone in wheat and oat based bran supplements sold in the Spanish market. | 2013 | Food Chem. Toxicol. | pmid:23201447 |
| Pestka JJ et al. | Effect of dietary administration of the trichothecene vomitoxin (deoxynivalenol) on IgA and IgG secretion by Peyer's patch and splenic lymphocytes. | 1990 | Food Chem. Toxicol. | pmid:2276698 |
| Rasooly L et al. | Polyspecific and autoreactive IgA secreted by hybridomas derived from Peyer's patches of vomitoxin-fed mice: characterization and possible pathogenic role in IgA nephropathy. | 1994 | Food Chem. Toxicol. | pmid:8206429 |
| Osselaere A et al. | Toxicokinetic study and absolute oral bioavailability of deoxynivalenol, T-2 toxin and zearalenone in broiler chickens. | 2013 | Food Chem. Toxicol. | pmid:23099502 |
| Banotai C et al. | Effects of intermittent vomitoxin exposure on body weight, immunoglobulin levels and haematuria in the B6C3F1 mouse. | 1999 | Food Chem. Toxicol. | pmid:10418952 |
| Collins TF et al. | Effects of deoxynivalenol (DON, vomitoxin) on in utero development in rats. | 2006 | Food Chem. Toxicol. | pmid:16325976 |
| Sundstøl Eriksen G et al. | Comparative cytotoxicity of deoxynivalenol, nivalenol, their acetylated derivatives and de-epoxy metabolites. | 2004 | Food Chem. Toxicol. | pmid:15019186 |
| Wallin S et al. | Biomonitoring of concurrent mycotoxin exposure among adults in Sweden through urinary multi-biomarker analysis. | 2015 | Food Chem. Toxicol. | pmid:26070503 |
| Arnold DL et al. | The toxicity of orally administered deoxynivalenol (vomitoxin) in rats and mice. | 1986 | Food Chem. Toxicol. | pmid:3781440 |
| Pestka JJ et al. | Emetic activity of the trichothecene 15-acetyldeoxynivalenol in swine. | 1987 | Food Chem. Toxicol. | pmid:3692388 |
| Sprando RL et al. | Characterization of the effect of deoxynivalenol on selected male reproductive endpoints. | 2005 | Food Chem. Toxicol. | pmid:15721211 |
| Escrivá L et al. | In vivo toxicity studies of fusarium mycotoxins in the last decade: a review. | 2015 | Food Chem. Toxicol. | pmid:25680507 |
| Khera KS et al. | A teratology study on vomitoxin (4-deoxynivalenol) in rabbits. | 1986 | Food Chem. Toxicol. | pmid:3744196 |
| Côté LM et al. | Lack of hepatic microsomal metabolism of deoxynivalenol and its metabolite, DOM-1. | 1987 | Food Chem. Toxicol. | pmid:3583156 |
| Pestka JJ and Zhou HR | Effects of tumor necrosis factor type 1 and 2 receptor deficiencies on anorexia, growth and IgA dysregulation in mice exposed to the trichothecene vomitoxin. | 2002 | Food Chem. Toxicol. | pmid:12176089 |
| Forsell JH et al. | Comparison of acute toxicities of deoxynivalenol (vomitoxin) and 15-acetyldeoxynivalenol in the B6C3F1 mouse. | 1987 | Food Chem. Toxicol. | pmid:3557238 |
| Lake BG et al. | Studies on the metabolism of deoxynivalenol in the rat. | 1987 | Food Chem. Toxicol. | pmid:3623350 |
| Sirot V et al. | Dietary exposure to mycotoxins and health risk assessment in the second French total diet study. | 2013 | Food Chem. Toxicol. | pmid:23137957 |
| Dänicke S and Döll S | A probiotic feed additive containing spores of Bacillus subtilis and B. licheniformis does not prevent absorption and toxic effects of the Fusarium toxin deoxynivalenol in piglets. | 2010 | Food Chem. Toxicol. | pmid:19796665 |
| Grove JF | The trichothecenes and their biosynthesis. | 2007 | Fortschr Chem Org Naturst | pmid:17302179 |
| Krishnaswamy R et al. | Lutein protects HT-29 cells against Deoxynivalenol-induced oxidative stress and apoptosis: prevention of NF-kappaB nuclear localization and down regulation of NF-kappaB and Cyclo-Oxygenase-2 expression. | 2010 | Free Radic. Biol. Med. | pmid:20347963 |
| Schneider L et al. | An enzyme linked immunoassay for the determination of deoxynivalenol in wheat based on chicken egg yolk antibodies. | 2000 | Fresenius J Anal Chem | pmid:11227446 |
| Walter S et al. | Components of the gene network associated with genotype-dependent response of wheat to the Fusarium mycotoxin deoxynivalenol. | 2008 | Funct. Integr. Genomics | pmid:18592282 |
| Jia H et al. | Quantitative trait loci conferring resistance to Fusarium head blight in barley respond differentially to Fusarium graminearum infection. | 2011 | Funct. Integr. Genomics | pmid:20865292 |
| Dong W and Pestka JJ | Persistent dysregulation of IgA production and IgA nephropathy in the B6C3F1 mouse following withdrawal of dietary vomitoxin (deoxynivalenol). | 1993 | Fundam Appl Toxicol | pmid:8432427 |
| Greene DM et al. | Effects of dihydrotestosterone and estradiol on experimental IgA nephropathy induced by vomitoxin. | 1995 | Fundam Appl Toxicol | pmid:7657054 |
| Pestka JJ and Dong W | Progressive serum IgE elevation in the B6C3F1 mouse following withdrawal of dietary vomitoxin (deoxynivalenol). | 1994 | Fundam Appl Toxicol | pmid:8005381 |
| Rotter BA et al. | Influence of low-level exposure to Fusarium mycotoxins on selected immunological and hematological parameters in young swine. | 1994 | Fundam Appl Toxicol | pmid:7958555 |
| Dong W et al. | Quantitative assessment of mesangial immunoglobulin A (IgA) accumulation, elevated circulating IgA immune complexes, and hematuria during vomitoxin-induced IgA nephropathy. | 1991 | Fundam Appl Toxicol | pmid:1833256 |
| Prelusky DB et al. | Excretion profiles of the mycotoxin deoxynivalenol, following oral and intravenous administration to sheep. | 1986 | Fundam Appl Toxicol | pmid:3699325 |
| Prelusky DB et al. | Tissue distribution and excretion of radioactivity following administration of 14C-labeled deoxynivalenol to White Leghorn hens. | 1986 | Fundam Appl Toxicol | pmid:3803758 |
| Arnold DL et al. | A short-term feeding study with deoxynivalenol (vomitoxin) using rats. | 1986 | Fundam Appl Toxicol | pmid:3710037 |
| Prelusky DB et al. | Pharmacokinetic fate of 14C-labeled deoxynivalenol in swine. | 1988 | Fundam Appl Toxicol | pmid:3356314 |
| Droce A et al. | PTR2 peptide transporters in Fusarium graminearum influence secondary metabolite production and sexual development. | 2017 | Fungal Biol | pmid:28390508 |
| Qi PF et al. | Effect of salicylic acid on Fusarium graminearum, the major causal agent of fusarium head blight in wheat. | 2012 | Fungal Biol | pmid:22385623 |
| Fu J et al. | Cystathionine gamma-synthase is essential for methionine biosynthesis in Fusarium graminearum. | 2013 | Fungal Biol | pmid:23332829 |
| Liu N et al. | The transcription cofactor FgSwi6 plays a role in growth and development, carbendazim sensitivity, cellulose utilization, lithium tolerance, deoxynivalenol production and virulence in the filamentous fungus Fusarium graminearum. | 2013 Sep-Oct | Fungal Genet. Biol. | pmid:23994322 |
| Jiang J et al. | FgVELB is associated with vegetative differentiation, secondary metabolism and virulence in Fusarium graminearum. | 2012 | Fungal Genet. Biol. | pmid:22713714 |
| Nguyen LN et al. | Autophagy-related lipase FgATG15 of Fusarium graminearum is important for lipid turnover and plant infection. | 2011 | Fungal Genet. Biol. | pmid:21094265 |
| Brown DW et al. | Functional demarcation of the Fusarium core trichothecene gene cluster. | 2004 | Fungal Genet. Biol. | pmid:14998528 |
| Brown DW et al. | A genetic and biochemical approach to study trichothecene diversity in Fusarium sporotrichioides and Fusarium graminearum. | 2001 | Fungal Genet. Biol. | pmid:11352533 |
| Nussbaumer T et al. | Joint Transcriptomic and Metabolomic Analyses Reveal Changes in the Primary Metabolism and Imbalances in the Subgenome Orchestration in the Bread Wheat Molecular Response to Fusarium graminearum. | 2015 | G3 (Bethesda) | pmid:26438291 |
| Fomenko VN et al. | [Changes in the hemostatic system after administration of the mycotoxin deoxynivalenol (vomitoxin) to rhesus monkeys]. | 1991 | Gematol Transfuziol | pmid:1769503 |
| Somers DJ et al. | Molecular mapping of novel genes controlling Fusarium head blight resistance and deoxynivalenol accumulation in spring wheat. | 2003 | Genome | pmid:12897863 |
| Tutel'ian VA et al. | [Embryotoxic effects of deoxynivalenol mycotoxin (vomitoxin) in rats]. | 1991 | Gig Sanit | pmid:1806423 |
| Razafimanjato H et al. | The ribotoxin deoxynivalenol affects the viability and functions of glial cells. | 2011 | Glia | pmid:21748807 |
| Zhou WC et al. | Effect of individual Sumai 3 chromosomes on resistance to scab spread within spikes and deoxynivalenol accumulation within kernels in wheat. | 2002 | Hereditas | pmid:12627831 |
| Rio B et al. | In vitro toxicity of trichothecenes on human erythroblastic progenitors. | 1997 | Hum Exp Toxicol | pmid:9426370 |
| Froquet R et al. | Trichothecene toxicity on human megakaryocyte progenitors (CFU-MK). | 2001 | Hum Exp Toxicol | pmid:11327514 |
| Bimczok D et al. | The Fusarium toxin deoxynivalenol disrupts phenotype and function of monocyte-derived dendritic cells in vivo and in vitro. | 2007 | Immunobiology | pmid:17869643 |
| Kidd MT et al. | Trichothecene mycotoxins depress the mononuclear-phagocytic system of young turkeys. | 1995 | Immunopharmacol Immunotoxicol | pmid:7650297 |
| Fornelli F et al. | Cytotoxicity induced by nivalenol, deoxynivalenol, and fumonisin B1 in the SF-9 insect cell line. | 2004 May-Jun | In Vitro Cell. Dev. Biol. Anim. | pmid:15479121 |
| Hubert J et al. | The effect of Tyrophagus putrescentiae on Fusarium poae transmission and fungal community in stored barley in a laboratory experiment. | 2014 | Insect Sci. | pmid:23955921 |
| Shi C et al. | Biocontrol of Fusarium graminearum growth and deoxynivalenol production in wheat kernels with bacterial antagonists. | 2014 | Int J Environ Res Public Health | pmid:24441510 |
| Skóra J et al. | Evaluation of Microbiological and Chemical Contaminants in Poultry Farms. | 2016 | Int J Environ Res Public Health | pmid:26861361 |
| Skládanka J et al. | Forage as a primary source of mycotoxins in animal diets. | 2011 | Int J Environ Res Public Health | pmid:21318013 |
| Ragab WS et al. | Fate of deoxynivalenol in contaminated wheat grain during preparation of Egyptian 'balila'. | 2007 | Int J Food Sci Nutr | pmid:17514535 |
| Rai M et al. | Emerging nanotechnology for detection of mycotoxins in food and feed. | 2015 | Int J Food Sci Nutr | pmid:26001087 |
| Gauthier L et al. | Metabolomics to Decipher the Chemical Defense of Cereals against Fusarium graminearum and Deoxynivalenol Accumulation. | 2015 | Int J Mol Sci | pmid:26492237 |
| He CH et al. | The individual and combined effects of deoxynivalenol and aflatoxin Bâ‚on primary hepatocytes of Cyprinus carpio. | 2010 | Int J Mol Sci | pmid:21152299 |
| Waché YJ et al. | Impact of deoxynivalenol on the intestinal microflora of pigs. | 2009 | Int J Mol Sci | pmid:19333431 |
| Awad WA et al. | The impact of the Fusarium mycotoxin deoxynivalenol on the health and performance of broiler chickens. | 2011 | Int J Mol Sci | pmid:22174646 |
| Vasatkova A et al. | Changes in metallothionein level in rat hepatic tissue after administration of natural mouldy wheat. | 2009 | Int J Mol Sci | pmid:19399242 |
| Debouck C et al. | Skeletal deformities induced by the intraperitoneal administration of deoxynivalenol (vomitoxin) in mice. | 2001 | Int Orthop | pmid:11482540 |
| Verheijden KA et al. | Inflammation-induced expression of the alarmin interleukin 33 can be suppressed by galacto-oligosaccharides. | 2015 | Int. Arch. Allergy Immunol. | pmid:26304032 |
| Mishra S et al. | Deoxynivalenol induced mouse skin tumor initiation: Elucidation of molecular mechanisms in human HaCaT keratinocytes. | 2016 | Int. J. Cancer | pmid:27389473 |
| Kottapalli B and Wolf-Hall CE | Effect of hot water treatments on the safety and quality of Fusarium-infected malting barley. | 2008 | Int. J. Food Microbiol. | pmid:18472174 |
| Abramson D et al. | Relationships among deoxynivalenol, ergosterol and Fusarium exoantigens in Canadian hard and soft wheat. | 1998 | Int. J. Food Microbiol. | pmid:9926999 |
| de Kuppler AL et al. | Genotyping and phenotyping of Fusarium graminearum isolates from Germany related to their mycotoxin biosynthesis. | 2011 | Int. J. Food Microbiol. | pmid:21889226 |
| Tanaka K et al. | Mycotoxins in rice. | 2007 | Int. J. Food Microbiol. | pmid:17913273 |
| Schaafsma AW and Hooker DC | Climatic models to predict occurrence of Fusarium toxins in wheat and maize. | 2007 | Int. J. Food Microbiol. | pmid:17900733 |
| Llorens A et al. | Influence of environmental factors on the biosynthesis of type B trichothecenes by isolates of Fusarium spp. from Spanish crops. | 2004 | Int. J. Food Microbiol. | pmid:15172484 |
| Beyer M et al. | Estimating deoxynivalenol contents of wheat samples containing different levels of Fusarium-damaged kernels by diffuse reflectance spectrometry and partial least square regression. | 2010 | Int. J. Food Microbiol. | pmid:20678823 |
| Connolly P and Corry JE | Effect of polymyxin B nonapeptide and polymyxin B sulphate on trichothecene mycotoxin sensitivity of yeasts using a conductimetric instrument. | 1990 | Int. J. Food Microbiol. | pmid:2168726 |
| Beyer M et al. | Estimating mycotoxin contents of Fusarium-damaged winter wheat kernels. | 2007 | Int. J. Food Microbiol. | pmid:17706313 |
| Yuen GY and Schoneweis SD | Strategies for managing Fusarium head blight and deoxynivalenol accumulation in wheat. | 2007 | Int. J. Food Microbiol. | pmid:17716767 |
| Oliveira PM et al. | Fundamental study on the influence of Fusarium infection on quality and ultrastructure of barley malt. | 2012 | Int. J. Food Microbiol. | pmid:22424933 |
| Neira MS et al. | The effects of bakery processing on natural deoxynivalenol contamination. | 1997 | Int. J. Food Microbiol. | pmid:9237118 |
| Reynoso MM et al. | Trichothecene genotypes and chemotypes in Fusarium graminearum strains isolated from wheat in Argentina. | 2011 | Int. J. Food Microbiol. | pmid:21320729 |
| Baturo-Ciesniewska A and Suchorzynska M | Verification of the effectiveness of SCAR (sequence characterized amplified region) primers for the identification of Polish strains of Fusarium culmorum and their potential ability to produce B-trichothecenes and zearalenone. | 2011 | Int. J. Food Microbiol. | pmid:21664712 |
| Ramirez ML et al. | Temperature and water activity effects on growth and temporal deoxynivalenol production by two Argentinean strains of Fusarium graminearum on irradiated wheat grain. | 2006 | Int. J. Food Microbiol. | pmid:16236377 |
| Fredlund E et al. | Deoxynivalenol and other selected Fusarium toxins in Swedish oats--occurrence and correlation to specific Fusarium species. | 2013 | Int. J. Food Microbiol. | pmid:23962918 |
| Lindblad M et al. | Deoxynivalenol and other selected Fusarium toxins in Swedish wheat--occurrence and correlation to specific Fusarium species. | 2013 | Int. J. Food Microbiol. | pmid:23962919 |
| Pan D et al. | Deoxynivalenol in barley samples from Uruguay. | 2007 | Int. J. Food Microbiol. | pmid:17067710 |
| Kottapalli B et al. | Effect of electron-beam irradiation on the safety and quality of Fusarium-infected malting barley. | 2006 | Int. J. Food Microbiol. | pmid:16780979 |
| Demeke T et al. | Development of a specific TaqMan real-time PCR assay for quantification of Fusarium graminearum clade 7 and comparison of fungal biomass determined by PCR with deoxynivalenol content in wheat and barley. | 2010 | Int. J. Food Microbiol. | pmid:20483187 |