Vomitoxin

Vomitoxin is a lipid of Prenol Lipids (PR) class. Vomitoxin is associated with abnormalities such as Infection and Gastroenteritis. The involved functions are known as mRNA Expression, Inflammation, Transcription, Genetic, Protein Biosynthesis and Adverse effects. Vomitoxin often locates in Lymphoid Tissue, Immune system, Bone Marrow and Plasma membrane. The associated genes with Vomitoxin are IMPACT gene, HIST1H1C gene and RBM39 gene. The related experimental models are Mouse Model.

Cross Reference

Introduction

To understand associated biological information of Vomitoxin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Vomitoxin?

Vomitoxin is suspected in Infection, Gastroenteritis and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Vomitoxin

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Inflammation D007249 119 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Esophageal Neoplasms D004938 20 associated lipids
Precancerous Conditions D011230 48 associated lipids
Stomach Neoplasms D013274 24 associated lipids
Hematuria D006417 13 associated lipids
Weight Gain D015430 101 associated lipids
Obesity D009765 29 associated lipids
Hyperplasia D006965 34 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Fetal Weight D020567 12 associated lipids
Immune Complex Diseases D007105 9 associated lipids
Glomerulonephritis, IGA D005922 7 associated lipids
Swine Diseases D013553 16 associated lipids
Poultry Diseases D011201 21 associated lipids
Thymus Neoplasms D013953 15 associated lipids
Bronchopneumonia D001996 7 associated lipids
Fetal Resorption D005327 15 associated lipids
Weight Loss D015431 56 associated lipids
Anorexia D000855 8 associated lipids
Mycoses D009181 18 associated lipids
Coronavirus Infections D018352 4 associated lipids
Mycotoxicosis D015651 5 associated lipids
Adrenocortical Carcinoma D018268 4 associated lipids
Splenic Diseases D013158 5 associated lipids
Kashin-Beck Disease D057767 2 associated lipids
Ascaridiasis D001198 1 associated lipids
Per page 10 20 50 | Total 29

PubChem Associated disorders and diseases

What pathways are associated with Vomitoxin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Vomitoxin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Vomitoxin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Vomitoxin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Vomitoxin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Vomitoxin?

Mouse Model

Mouse Model are used in the study 'Dietary fish oil suppresses experimental immunoglobulin a nephropathy in mice.' (Pestka JJ et al., 2002).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with Vomitoxin

Download all related citations
Per page 10 20 50 100 | Total 1588
Authors Title Published Journal PubMed Link
Burrows EP and Szafraniec LL Hypochlorite-promoted transformations of trichothecenes, 3. Deoxynivalenol. 1987 Nov-Dec J. Nat. Prod. pmid:2832543
Jia Q et al. Docosahexaenoic acid attenuates mycotoxin-induced immunoglobulin a nephropathy, interleukin-6 transcription, and mitogen-activated protein kinase phosphorylation in mice. 2004 J. Nutr. pmid:15570035
Jia Q et al. Docosahexaenoic acid and eicosapentaenoic acid, but not alpha-linolenic acid, suppress deoxynivalenol-induced experimental IgA nephropathy in mice. 2004 J. Nutr. pmid:15173396
Akbari P et al. Galacto-oligosaccharides Protect the Intestinal Barrier by Maintaining the Tight Junction Network and Modulating the Inflammatory Responses after a Challenge with the Mycotoxin Deoxynivalenol in Human Caco-2 Cell Monolayers and B6C3F1 Mice. 2015 J. Nutr. pmid:26019243
Jia Q et al. Docosahexaenoic acid consumption inhibits deoxynivalenol-induced CREB/ATF1 activation and IL-6 gene transcription in mouse macrophages. 2006 J. Nutr. pmid:16424113
Pinton P et al. Deoxynivalenol impairs porcine intestinal barrier function and decreases the protein expression of claudin-4 through a mitogen-activated protein kinase-dependent mechanism. 2010 J. Nutr. pmid:20861219
Pestka JJ et al. Dietary fish oil suppresses experimental immunoglobulin a nephropathy in mice. 2002 J. Nutr. pmid:11823588
Maresca M et al. The mycotoxin deoxynivalenol affects nutrient absorption in human intestinal epithelial cells. 2002 J. Nutr. pmid:12221236
Moon Y and Pestka JJ Deoxynivalenol-induced mitogen-activated protein kinase phosphorylation and IL-6 expression in mice suppressed by fish oil. 2003 J. Nutr. Biochem. pmid:14690764
Shi Y and Pestka JJ Attenuation of mycotoxin-induced IgA nephropathy by eicosapentaenoic acid in the mouse: dose response and relation to IL-6 expression. 2006 J. Nutr. Biochem. pmid:16524712
Shi Y and Pestka JJ Mechanisms for suppression of interleukin-6 expression in peritoneal macrophages from docosahexaenoic acid-fed mice. 2009 J. Nutr. Biochem. pmid:18602807
Kinser S et al. Truncated deoxynivalenol-induced splenic immediate early gene response in mice consuming (n-3) polyunsaturated fatty acids. 2005 J. Nutr. Biochem. pmid:15681167
Fioramonti J et al. The mycotoxin, deoxynivalenol, delays gastric emptying through serotonin-3 receptors in rodents. 1993 J. Pharmacol. Exp. Ther. pmid:8371135
Mudili V et al. Mould incidence and mycotoxin contamination in freshly harvested maize kernels originated from India. 2014 J. Sci. Food Agric. pmid:24609945
Garcia D et al. Impact of cycling temperatures on Fusarium verticillioides and Fusarium graminearum growth and mycotoxins production in soybean. 2012 J. Sci. Food Agric. pmid:22555960
Juodeikiene G et al. Benefits of β-xylanase for wheat biomass conversion to bioethanol. 2012 J. Sci. Food Agric. pmid:21744360
Torelli E et al. The influence of local factors on the prediction of fumonisin contamination in maize. 2012 J. Sci. Food Agric. pmid:22228027
Tran ST et al. A survey of free and conjugated deoxynivalenol in the 2008 corn crop in Ontario, Canada. 2012 J. Sci. Food Agric. pmid:21997524
Gilbert J et al. A survey of the occurrence of the trichothecene mycotoxin deoxynivalenol (vomitoxin) in UK grown barley and in imported maize by combined gas chromatography-mass spectrometry. 1983 J. Sci. Food Agric. pmid:6843094
Qiu J et al. Effect of preceding crop on Fusarium species and mycotoxin contamination of wheat grains. 2016 J. Sci. Food Agric. pmid:26867679
Zhang J et al. Simultaneous detection of deoxynivalenol and zearalenone by dual-label time-resolved fluorescence immunoassay. 2011 J. Sci. Food Agric. pmid:20945513
Ok HE et al. Determination of deoxynivalenol in cereal-based foods and estimation of dietary exposure. 2009 J. Toxicol. Environ. Health Part A pmid:20077214
Liu J et al. Regulation of IL-8 promoter activity by verrucarin A in human monocytic THP-1 cells. 2014 J. Toxicol. Environ. Health Part A pmid:25119735
Kinser S et al. Gene expression profiling in spleens of deoxynivalenol-exposed mice: immediate early genes as primary targets. 2004 J. Toxicol. Environ. Health Part A pmid:15371230
Drochner W et al. Serum IgA-promoting effects induced by feed loads containing isolated deoxynivalenol (DON) in growing piglets. 2004 J. Toxicol. Environ. Health Part A pmid:15205033
Amuzie CJ et al. Effects of deoxynivalenol consumption on body weight and adiposity in the diet-induced obese mouse. 2011 J. Toxicol. Environ. Health Part A pmid:21432715
Lee MG et al. Effects of satratoxins and other macrocyclic trichothecenes on IL-2 production and viability of EL-4 thymoma cells. 1999 J. Toxicol. Environ. Health Part A pmid:10494915
Zhou HR et al. Amplified proinflammatory cytokine expression and toxicity in mice coexposed to lipopolysaccharide and the trichothecene vomitoxin (deoxynivalenol). 1999 J. Toxicol. Environ. Health Part A pmid:10344227
Sugita-Konishi Y and Pestka JJ Differential upregulation of TNF-alpha, IL-6, and IL-8 production by deoxynivalenol (vomitoxin) and other 8-ketotrichothecenes in a human macrophage model. 2001 J. Toxicol. Environ. Health Part A pmid:11766169
Wong SS et al. Effects of vomitoxin (deoxynivalenol) on the binding of transcription factors AP-1, NF-kappaB, and NF-IL6 in raw 264.7 macrophage cells. 2002 J. Toxicol. Environ. Health Part A pmid:12167214
Osweiler GD et al. Relationship of mycotoxins to swine reproductive failure. 1990 J. Vet. Diagn. Invest. pmid:2151029
Johnson PJ et al. Effect of feeding deoxynivalenol (vomitoxin)-contaminated barley to horses. 1997 J. Vet. Diagn. Invest. pmid:9211250
Wada K et al. Effects of mycotoxins on chemiluminescent response and cytokine mRNA expression of bovine neutrophils. 2010 J. Vet. Med. Sci. pmid:20622479
Pralatnet S et al. The fate and tissue disposition of deoxynivalenol in broiler chickens. 2015 J. Vet. Med. Sci. pmid:25843039
Murata H et al. Reduction of deoxynivalenol contaminating corn silage by short-term ultraviolet irradiation: a pilot study. 2011 J. Vet. Med. Sci. pmid:21467760
Mikami O et al. The effects of acute exposure to deoxynivalenol on some inflammatory parameters in miniature pigs. 2011 J. Vet. Med. Sci. pmid:21224530
Takayama H et al. Suppressive effect of deoxynivalenol, a Fusarium mycotoxin, on bovine and porcine neutrophil chemiluminescence: an in vitro study. 2005 J. Vet. Med. Sci. pmid:15942140
Poapolathep A et al. The effect of naringenin on the fate and disposition of deoxynivalenol in piglets. 2010 J. Vet. Med. Sci. pmid:20467205
Mikami O et al. Induction of apoptotic lesions in liver and lymphoid tissues and modulation of cytokine mRNA expression by acute exposure to deoxynivalenol in piglets. 2010 J. Vet. Sci. pmid:20458150
Kim EJ et al. Plasma haptoglobin and immunoglobulins as diagnostic indicators of deoxynivalenol intoxication. 2008 J. Vet. Sci. pmid:18716445
Lee HM et al. Development of a monoclonal antibody against deoxynivalenol for magnetic nanoparticle-based extraction and an enzyme-linked immunosorbent assay. 2013 J. Vet. Sci. pmid:23388439
Chen F et al. The combination of deoxynivalenol and zearalenone at permitted feed concentrations causes serious physiological effects in young pigs. 2008 J. Vet. Sci. pmid:18296887
Boston S et al. Consumption of deoxynivalenol-contaminated wheat by mallard ducks under experimental conditions. 1996 J. Wildl. Dis. pmid:8627931
Etzel RA Mycotoxins. 2002 Jan 23-30 JAMA pmid:11798344
León-S FE et al. Mycotoxins in myelopathies of man. 1996 Lancet pmid:8855894
Hope R et al. Comparison of environmental profiles for growth and deoxynivalenol production by Fusarium culmorum and F. graminearum on wheat grain. 2005 Lett. Appl. Microbiol. pmid:15752221
Schnerr H et al. Correlation between DNA of trichothecene-producing Fusarium species and deoxynivalenol concentrations in wheat-samples. 2002 Lett. Appl. Microbiol. pmid:12100586
Hope R and Magan N Two-dimensional environmental profiles of growth, deoxynivalenol and nivalenol production by Fusarium culmorum on a wheat-based substrate. 2003 Lett. Appl. Microbiol. pmid:12803560
Cazzaniga D et al. Mycotoxins inactivation by extrusion cooking of corn flour. 2001 Lett. Appl. Microbiol. pmid:11472523
Payros D et al. The Food Contaminant Deoxynivalenol Exacerbates the Genotoxicity of Gut Microbiota. 2017 MBio pmid:28292979