Vomitoxin

Vomitoxin is a lipid of Prenol Lipids (PR) class. Vomitoxin is associated with abnormalities such as Infection and Gastroenteritis. The involved functions are known as mRNA Expression, Inflammation, Transcription, Genetic, Protein Biosynthesis and Adverse effects. Vomitoxin often locates in Lymphoid Tissue, Immune system, Bone Marrow and Plasma membrane. The associated genes with Vomitoxin are IMPACT gene, HIST1H1C gene and RBM39 gene. The related experimental models are Mouse Model.

Cross Reference

Introduction

To understand associated biological information of Vomitoxin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Vomitoxin?

Vomitoxin is suspected in Infection, Gastroenteritis and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Vomitoxin

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Inflammation D007249 119 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Esophageal Neoplasms D004938 20 associated lipids
Precancerous Conditions D011230 48 associated lipids
Stomach Neoplasms D013274 24 associated lipids
Hematuria D006417 13 associated lipids
Weight Gain D015430 101 associated lipids
Obesity D009765 29 associated lipids
Hyperplasia D006965 34 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Fetal Weight D020567 12 associated lipids
Immune Complex Diseases D007105 9 associated lipids
Glomerulonephritis, IGA D005922 7 associated lipids
Swine Diseases D013553 16 associated lipids
Poultry Diseases D011201 21 associated lipids
Thymus Neoplasms D013953 15 associated lipids
Bronchopneumonia D001996 7 associated lipids
Fetal Resorption D005327 15 associated lipids
Weight Loss D015431 56 associated lipids
Anorexia D000855 8 associated lipids
Mycoses D009181 18 associated lipids
Coronavirus Infections D018352 4 associated lipids
Mycotoxicosis D015651 5 associated lipids
Adrenocortical Carcinoma D018268 4 associated lipids
Splenic Diseases D013158 5 associated lipids
Kashin-Beck Disease D057767 2 associated lipids
Ascaridiasis D001198 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Vomitoxin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Vomitoxin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Vomitoxin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Vomitoxin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Vomitoxin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Vomitoxin?

Mouse Model

Mouse Model are used in the study 'Dietary fish oil suppresses experimental immunoglobulin a nephropathy in mice.' (Pestka JJ et al., 2002).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Vomitoxin

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Per page 10 20 50 100 | Total 1588
Authors Title Published Journal PubMed Link
Papadopoulou-Bouraoui A et al. Screening survey of deoxynivalenol in beer from the European market by an enzyme-linked immunosorbent assay. 2004 Food Addit Contam pmid:15204540
Drochner W et al. Serum IgA-promoting effects induced by feed loads containing isolated deoxynivalenol (DON) in growing piglets. 2004 J. Toxicol. Environ. Health Part A pmid:15205033
Dänicke S et al. On the toxicokinetics and the metabolism of deoxynivalenol (DON) in the pig. 2004 Arch Anim Nutr pmid:15195910
Konjević D et al. A pathological condition possibly caused by spontaneous trichotecene poisoning in Brahma poultry: first report. 2004 Avian Pathol. pmid:15223563
Llorens A et al. Influence of environmental factors on the biosynthesis of type B trichothecenes by isolates of Fusarium spp. from Spanish crops. 2004 Int. J. Food Microbiol. pmid:15172484
Huang XH et al. [Carcinogenic effects of sterigmatocystin and deoxynivalenol in NIH mice]. 2004 Zhonghua Zhong Liu Za Zhi pmid:15733384
Manthey FA et al. Microbial loads, mycotoxins, and quality of durum wheat from the 2001 harvest of the northern plains region of the United States. 2004 J. Food Prot. pmid:15083730
Dänicke S et al. Effects of graded levels of Fusarium toxin contaminated wheat in diets for fattening pigs on growth performance, nutrient digestibility, deoxynivalenol balance and clinical serum characteristics. 2004 Arch Anim Nutr pmid:15085961
Völkl A et al. Microbial detoxification of mycotoxin deoxynivalenol. 2004 J. Basic Microbiol. pmid:15069674
Döll S et al. The effect of increasing concentrations of Fusarium toxins in piglet diets on histological parameters of the uterus and vagina. 2004 Arch Anim Nutr pmid:15595624
Döll S et al. In vitro studies on the evaluation of mycotoxin detoxifying agents for their efficacy on deoxynivalenol and zearalenone. 2004 Arch Anim Nutr pmid:15570745
Brown DW et al. Functional demarcation of the Fusarium core trichothecene gene cluster. 2004 Fungal Genet. Biol. pmid:14998528
Sundstøl Eriksen G et al. Comparative cytotoxicity of deoxynivalenol, nivalenol, their acetylated derivatives and de-epoxy metabolites. 2004 Food Chem. Toxicol. pmid:15019186
Choi GH et al. Cloning, expression, and characterization of single-chain variable fragment antibody against mycotoxin deoxynivalenol in recombinant Escherichia coli. 2004 Protein Expr. Purif. pmid:15039070
Avantaggiato G et al. Evaluation of the intestinal absorption of deoxynivalenol and nivalenol by an in vitro gastrointestinal model, and the binding efficacy of activated carbon and other adsorbent materials. 2004 Food Chem. Toxicol. pmid:15046828
Alexander NJ et al. Expression of Tri15 in Fusarium sporotrichioides. 2004 Curr. Genet. pmid:14624310
Minervini F et al. Toxicity and apoptosis induced by the mycotoxins nivalenol, deoxynivalenol and fumonisin B1 in a human erythroleukemia cell line. 2004 Toxicol In Vitro pmid:14630058
Dänicke S et al. Effects of long-term storage on Fusarium toxin concentrations in wheat--sources of error of the analytical results. 2004 Arch Anim Nutr pmid:15732583
Whitaker TB et al. Estimating deoxynivalenol in shelled corn barge lots by measuring deoxynivalenol in corn screenings. 2003 Nov-Dec J AOAC Int pmid:14979701
Samar MM et al. Distribution of deoxynivalenol in wheat, wheat flour, bran, and gluten, and variability associated with the test procedure. 2003 May-Jun J AOAC Int pmid:12852575
Tiemann U et al. Influence of the mycotoxins alpha- and beta-zearalenol and deoxynivalenol on the cell cycle of cultured porcine endometrial cells. 2003 Mar-Apr Reprod. Toxicol. pmid:12642154
Plattner RD and Maragos CM Determination of deoxynivalenol and nivalenol in corn and wheat by liquid chromatography with electrospray mass spectrometry. 2003 Jan-Feb J AOAC Int pmid:12607741
Chung YJ et al. Up-regulation of macrophage inflammatory protein-2 and complement 3A receptor by the trichothecenes deoxynivalenol and satratoxin G. 2003 Toxicology pmid:12604170
Zhou HR et al. Rapid, sequential activation of mitogen-activated protein kinases and transcription factors precedes proinflammatory cytokine mRNA expression in spleens of mice exposed to the trichothecene vomitoxin. 2003 Toxicol. Sci. pmid:12604842
Lori GA et al. Fusarium graminearum and deoxynivalenol contamination in the durum wheat area of Argentina. 2003 Microbiol. Res. pmid:12608577
Clifford LJ et al. An improved method for the purification of the trichothecene deoxynivalenol (vomitoxin) from Fusarium graminearum culture. 2003 J. Agric. Food Chem. pmid:12517120
Weiss R et al. Improving methods of analysis for mycotoxins: molecularly imprinted polymers for deoxynivalenol and zearalenone. 2003 Food Addit Contam pmid:12775482
Rasmussen PH et al. Deoxynivalenol and other Fusarium toxins in wheat and rye flours on the Danish market. 2003 Food Addit Contam pmid:12775483
Wilbert FM and Kemmelmeier C Identification of deoxynivalenol, 3-acetyldeoxynivalenol, and zearalenone in galactose oxidase-producing isolates of Fusarium graminearum. 2003 J. Basic Microbiol. pmid:12746857
Pestka JJ Deoxynivalenol-induced IgA production and IgA nephropathy-aberrant mucosal immune response with systemic repercussions. 2003 Toxicol. Lett. pmid:12676476
Zielonka L et al. Influence of low doses of deoxynivalenol applied per os on chosen indexes of immune response in swine. 2003 Pol J Vet Sci pmid:14509371
Moon Y and Pestka JJ Deoxynivalenol-induced mitogen-activated protein kinase phosphorylation and IL-6 expression in mice suppressed by fish oil. 2003 J. Nutr. Biochem. pmid:14690764
Chung YJ et al. Transcriptional and posttranscriptional roles for p38 mitogen-activated protein kinase in upregulation of TNF-alpha expression by deoxynivalenol (vomitoxin). 2003 Toxicol. Appl. Pharmacol. pmid:14644621
Razzazi-Fazeli E et al. Simultaneous determination of major B-trichothecenes and the de-epoxy-metabolite of deoxynivalenol in pig urine and maize using high-performance liquid chromatography-mass spectrometry. 2003 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:14552813
Froquet R et al. Do trichothecenes reduce viability of circulating blood cells and modify haemostasis parameters? 2003 Mycopathologia pmid:14682462
Peng SQ and Yang JS [Effect of deoxynivalenol on action potentials of cultured cardiomyocytes and the protective effects of selenium]. 2003 Zhonghua Yu Fang Yi Xue Za Zhi pmid:14703497
Cirillo T et al. Evaluation of conventional and organic italian foodstuffs for deoxynivalenol and fumonisins B(1) and B(2). 2003 J. Agric. Food Chem. pmid:14690407
Yumbe-Guevara BE et al. Effects of heating procedures on deoxynivalenol, nivalenol and zearalenone levels in naturally contaminated barley and wheat. 2003 Food Addit Contam pmid:14726277
Islam Z et al. Differential induction of glucocorticoid-dependent apoptosis in murine lymphoid subpopulations in vivo following coexposure to lipopolysaccharide and vomitoxin (deoxynivalenol). 2003 Toxicol. Appl. Pharmacol. pmid:12649039
Moon Y and Pestka JJ Cyclooxygenase-2 mediates interleukin-6 upregulation by vomitoxin (deoxynivalenol) in vitro and in vivo. 2003 Toxicol. Appl. Pharmacol. pmid:12649040
Zhou HR et al. Role of double-stranded RNA-activated protein kinase R (PKR) in deoxynivalenol-induced ribotoxic stress response. 2003 Toxicol. Sci. pmid:12773753
Islam Z and Pestka JJ Role of IL-1(beta) in endotoxin potentiation of deoxynivalenol-induced corticosterone response and leukocyte apoptosis in mice. 2003 Toxicol. Sci. pmid:12773775
Omurtag GZ and BeyoÄŸlu D Occurrence of deoxynivalenol (vomitoxin) in processed cereals and pulses in Turkey. 2003 Food Addit Contam pmid:12775484
Poppenberger B et al. Detoxification of the Fusarium mycotoxin deoxynivalenol by a UDP-glucosyltransferase from Arabidopsis thaliana. 2003 J. Biol. Chem. pmid:12970342
Tüdös AJ et al. Rapid surface plasmon resonance-based inhibition assay of deoxynivalenol. 2003 J. Agric. Food Chem. pmid:13129282
Kim HS et al. Polymorphism of trichothecene biosynthesis genes in deoxynivalenol- and nivalenol-producing Fusarium graminearum isolates. 2003 Mycol. Res. pmid:12747330
Sugita-Konishi Y [Current worldwide regulation for mycotoxins]. 2003 Shokuhin Eiseigaku Zasshi pmid:12749204
Moss MO Fusarial toxins: are they a cause for concern? 2003 Vet. J. pmid:12672361
Nasir MS and Jolley ME Fluorescence polarization (FP) assays for the determination of grain mycotoxins (fumonisins, DON vomitoxin and aflatoxins). 2003 Comb. Chem. High Throughput Screen. pmid:12678705
Dänicke S et al. Effects of graded levels of Fusarium toxin-contaminated wheat and of a detoxifying agent in broiler diets on performance, nutrient digestibility and blood chemical parameters. 2003 Br. Poult. Sci. pmid:12737233