Vomitoxin is a lipid of Prenol Lipids (PR) class. Vomitoxin is associated with abnormalities such as Infection and Gastroenteritis. The involved functions are known as mRNA Expression, Inflammation, Transcription, Genetic, Protein Biosynthesis and Adverse effects. Vomitoxin often locates in Lymphoid Tissue, Immune system, Bone Marrow and Plasma membrane. The associated genes with Vomitoxin are IMPACT gene, HIST1H1C gene and RBM39 gene. The related experimental models are Mouse Model.
To understand associated biological information of Vomitoxin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Vomitoxin is suspected in Infection, Gastroenteritis and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Vomitoxin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
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Mouse Model are used in the study 'Dietary fish oil suppresses experimental immunoglobulin a nephropathy in mice.' (Pestka JJ et al., 2002).
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Authors | Title | Published | Journal | PubMed Link |
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Li S et al. | Superinduction of IL-2 gene expression by vomitoxin (deoxynivalenol) involves increased mRNA stability. | 1997 | Toxicol. Appl. Pharmacol. | pmid:9439728 |
Tacke BK and Casper HH | Determination of deoxynivalenol in wheat, barley, and malt by column cleanup and gas chromatography with electron capture detection. | 1996 Mar-Apr | J AOAC Int | pmid:8920135 |
Trucksess MW et al. | Determination and survey of deoxynivalenol in white flour, whole wheat flour, and bran. | 1996 Jul-Aug | J AOAC Int | pmid:8757447 |
León-S FE et al. | Mycotoxins in myelopathies of man. | 1996 | Lancet | pmid:8855894 |
Rotter BA et al. | Toxicology of deoxynivalenol (vomitoxin). | 1996 | J Toxicol Environ Health | pmid:8637056 |
Boston S et al. | Consumption of deoxynivalenol-contaminated wheat by mallard ducks under experimental conditions. | 1996 | J. Wildl. Dis. | pmid:8627931 |
Prelusky DB | A study on the effect of deoxynivalenol on serotonin receptor binding in pig brain membranes. | 1996 | J Environ Sci Health B | pmid:8751451 |
Ouyang YL et al. | Vomitoxin-mediated IL-2, IL-4, and IL-5 superinduction in murine CD4+ T cells stimulated with phorbol ester calcium ionophore: relation to kinetics of proliferation. | 1996 | Toxicol. Appl. Pharmacol. | pmid:8658534 |
Ouyang YL et al. | Effects of vomitoxin (deoxynivalenol) on transcription factor NF-kappa B/Rel binding activity in murine EL-4 thymoma and primary CD4+ T cells. | 1996 | Toxicol. Appl. Pharmacol. | pmid:8887449 |
Rotter BA et al. | The role of tryptophan in DON-induced feed rejection. | 1996 | J Environ Sci Health B | pmid:8896360 |
González HH et al. | Deoxynivalenol and contaminant mycoflora in freshly harvested Argentinian wheat in 1993. | 1996 | Mycopathologia | pmid:9091829 |
Snijders CH et al. | Analysis of Fusarium causing dermal toxicosis in marram grass planters. | 1996 | Mycopathologia | pmid:9063007 |
O'Neill K et al. | The influence of gamma radiation and substrate on mycotoxin production by Fusarium culmorum IMI 309344. | 1996 | J. Appl. Bacteriol. | pmid:8939030 |
Iverson F et al. | Chronic feeding study of deoxynivalenol in B6C3F1 male and female mice. | 1995-1996 | Teratog., Carcinog. Mutagen. | pmid:8732880 |
Yoshizawa T and Jin YZ | Natural occurrence of acetylated derivatives of deoxynivalenol and nivalenol in wheat and barley in Japan. | 1995 Sep-Oct | Food Addit Contam | pmid:8522034 |
Trucksess MW et al. | Survey of deoxynivalenol in U.S. 1993 wheat and barley crops by enzyme-linked immunosorbent assay. | 1995 May-Jun | J AOAC Int | pmid:7756875 |
Parent-Massin D and Thouvenot D | In vitro toxicity of trichothecenes on rat haematopoietic progenitors. | 1995 Jan-Feb | Food Addit Contam | pmid:7758630 |
Lambert LA et al. | Lack of initiation and promotion potential of deoxynivalenol for skin tumorigenesis in Sencar mice. | 1995 | Food Chem. Toxicol. | pmid:7896232 |
Azcona-Olivera JI et al. | Effects of vomitoxin (deoxynivalenol) and cycloheximide on IL-2, 4, 5 and 6 secretion and mRNA levels in murine CD4+ cells. | 1995 | Food Chem. Toxicol. | pmid:7797171 |
Greene DM et al. | Effects of dihydrotestosterone and estradiol on experimental IgA nephropathy induced by vomitoxin. | 1995 | Fundam Appl Toxicol | pmid:7657054 |
Kidd MT et al. | Trichothecene mycotoxins depress the mononuclear-phagocytic system of young turkeys. | 1995 | Immunopharmacol Immunotoxicol | pmid:7650297 |
Cossette F and Miller JD | Phytotoxic effect of deoxynivalenol and gibberella ear rot resistance of corn. | 1995 | Nat. Toxins | pmid:8581324 |
Tseng TC et al. | Natural occurrence of mycotoxins in Fusarium infected beans. | 1995 | Microbios | pmid:8569524 |
Ouyang YL et al. | Effects of trichothecene structure on cytokine secretion and gene expression in murine CD4+ T-cells. | 1995 | Toxicology | pmid:8560498 |
Tani N et al. | Antiviral activity of trichothecene mycotoxins (deoxynivalenol, fusarenon-X, and nivalenol) against herpes simplex virus types 1 and 2. | 1995 | Microbiol. Immunol. | pmid:7494505 |
Gilbert J | Analysis of mycotoxins in food and feed: certification of DON in wheat and maize. | 1995 | Nat. Toxins | pmid:7582627 |
Azcona-Olivera JI et al. | Induction of cytokine mRNAs in mice after oral exposure to the trichothecene vomitoxin (deoxynivalenol): relationship to toxin distribution and protein synthesis inhibition. | 1995 | Toxicol. Appl. Pharmacol. | pmid:7597700 |
Böswald C et al. | Metabolism of the Fusarium mycotoxins zearalenone and deoxynivalenol by yeast strains of technological relevance. | 1995 | Nat. Toxins | pmid:7648022 |
Ruprich J and Ostry V | Determination of the mycotoxin deoxynivalenol in beer by commercial elisa tests and estimation of the exposure dose from beer for the population in the Czech Republic. | 1995 | Cent. Eur. J. Public Health | pmid:8903526 |
Fernandez C et al. | Determination of deoxynivalenol in 1991 U.S. winter and spring wheat by high-performance thin-layer chromatography. | 1994 May-Jun | J AOAC Int | pmid:8012211 |
Parent-Massin D et al. | In vitro toxicity of trichothecenes on human haematopoietic progenitors. | 1994 Jul-Aug | Food Addit Contam | pmid:7958114 |
Bergsjø B and Kaldhusdal M | No association found between the ascites syndrome in broilers and feeding of oats contaminated with deoxynivalenol up to thirty-five days of age. | 1994 | Poult. Sci. | pmid:7862615 |
Pestka JJ et al. | Flow cytometric analysis of the effects of in vitro exposure to vomitoxin (deoxynivalenol) on apoptosis in murine T, B and IgA+ cells. | 1994 | Food Chem. Toxicol. | pmid:7813984 |
Greene DM et al. | Vomitoxin (deoxynivalenol)-induced IgA nephropathy in the B6C3F1 mouse: dose response and male predilection. | 1994 | Toxicology | pmid:7940564 |
Rotter BA et al. | Optimization of the mouse bioassay for deoxynivalenol as an alternative to large animal studies. | 1994 | Bull Environ Contam Toxicol | pmid:7833598 |
Warner RL et al. | In vitro effects of vomitoxin (deoxynivalenol) on T-cell interleukin production and IgA secretion. | 1994 | Food Chem. Toxicol. | pmid:7913905 |
Rizzo AF et al. | Protective effect of antioxidants against free radical-mediated lipid peroxidation induced by DON or T-2 toxin. | 1994 | Zentralbl Veterinarmed A | pmid:8091893 |
Zakharova LP et al. | [Grain contamination by deoxynivalenol in Russia]. | 1994 | Vopr Pitan | pmid:7975431 |
Greene DM et al. | Role of gender and strain in vomitoxin-induced dysregulation of IgA production and IgA nephropathy in the mouse. | 1994 | J Toxicol Environ Health | pmid:8078091 |
Lu G et al. | [Studies on deoxynivalenol contamination in grain and its products in Anhui Province]. | 1994 | Zhonghua Yu Fang Yi Xue Za Zhi | pmid:8082456 |
Ossenkopp KP et al. | Deoxynivalenol (vomitoxin)-induced conditioned taste aversions in rats are mediated by the chemosensitive area postrema. | 1994 | Pharmacol. Biochem. Behav. | pmid:8146230 |
Mirocha CJ et al. | Production of trichothecene mycotoxins by Fusarium graminearum and Fusarium culmorum on barley and wheat. | 1994 | Mycopathologia | pmid:7708088 |
Dong W et al. | Elevated gene expression and production of interleukins 2, 4, 5, and 6 during exposure to vomitoxin (deoxynivalenol) and cycloheximide in the EL-4 thymoma. | 1994 | Toxicol. Appl. Pharmacol. | pmid:8048072 |
Pestka JJ and Dong W | Progressive serum IgE elevation in the B6C3F1 mouse following withdrawal of dietary vomitoxin (deoxynivalenol). | 1994 | Fundam Appl Toxicol | pmid:8005381 |
Prelusky DB | The effect of deoxynivalenol on serotoninergic neurotransmitter levels in pig blood. | 1994 | J Environ Sci Health B | pmid:7527434 |
Rotter BA et al. | Influence of low-level exposure to Fusarium mycotoxins on selected immunological and hematological parameters in young swine. | 1994 | Fundam Appl Toxicol | pmid:7958555 |
Yuwai KE et al. | Occurrence of nivalenol, deoxynivalenol, and zearalenone in imported cereals in Papua, New Guinea. | 1994 | Nat. Toxins | pmid:8032690 |
Prelusky DB et al. | Effects of low-level dietary deoxynivalenol on haematological and clinical parameters of the pig. | 1994 | Nat. Toxins | pmid:8087437 |
Rasooly L et al. | Polyspecific and autoreactive IgA secreted by hybridomas derived from Peyer's patches of vomitoxin-fed mice: characterization and possible pathogenic role in IgA nephropathy. | 1994 | Food Chem. Toxicol. | pmid:8206429 |
Kollarczik B et al. | In vitro transformation of the Fusarium mycotoxins deoxynivalenol and zearalenone by the normal gut microflora of pigs. | 1994 | Nat. Toxins | pmid:8087428 |