Vomitoxin

Vomitoxin is a lipid of Prenol Lipids (PR) class. Vomitoxin is associated with abnormalities such as Infection and Gastroenteritis. The involved functions are known as mRNA Expression, Inflammation, Transcription, Genetic, Protein Biosynthesis and Adverse effects. Vomitoxin often locates in Lymphoid Tissue, Immune system, Bone Marrow and Plasma membrane. The associated genes with Vomitoxin are IMPACT gene, HIST1H1C gene and RBM39 gene. The related experimental models are Mouse Model.

Cross Reference

Introduction

To understand associated biological information of Vomitoxin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Vomitoxin?

Vomitoxin is suspected in Infection, Gastroenteritis and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Vomitoxin

MeSH term MeSH ID Detail
Weight Loss D015431 56 associated lipids
Anorexia D000855 8 associated lipids
Mycoses D009181 18 associated lipids
Coronavirus Infections D018352 4 associated lipids
Mycotoxicosis D015651 5 associated lipids
Adrenocortical Carcinoma D018268 4 associated lipids
Splenic Diseases D013158 5 associated lipids
Kashin-Beck Disease D057767 2 associated lipids
Ascaridiasis D001198 1 associated lipids
Per page 10 20 50 | Total 29

PubChem Associated disorders and diseases

What pathways are associated with Vomitoxin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Vomitoxin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Vomitoxin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Vomitoxin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Vomitoxin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Vomitoxin?

Mouse Model

Mouse Model are used in the study 'Dietary fish oil suppresses experimental immunoglobulin a nephropathy in mice.' (Pestka JJ et al., 2002).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Vomitoxin

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Per page 10 20 50 100 | Total 1588
Authors Title Published Journal PubMed Link
Urban M et al. Arabidopsis is susceptible to the cereal ear blight fungal pathogens Fusarium graminearum and Fusarium culmorum. 2002 Plant J. pmid:12492838
Clifford LJ et al. An improved method for the purification of the trichothecene deoxynivalenol (vomitoxin) from Fusarium graminearum culture. 2003 J. Agric. Food Chem. pmid:12517120
Wang H et al. [Effects of deoxynivalenol on proliferation and tumor necrosis factor-alpha secretion of human peripheral blood mononuclear cells in vitro]. 2000 Wei Sheng Yan Jiu pmid:12520964
Perkowski J and Kaczmarek Z Distribution of deoxynivalenol and 3-acetyldeoxynivalenol in naturally contaminated and Fusarium culmorum infected triticale samples. 2002 Nahrung pmid:12577591
Okubara PA et al. Engineering deoxynivalenol metabolism in wheat through the expression of a fungal trichothecene acetyltransferase gene. 2002 Theor. Appl. Genet. pmid:12582873
Chung YJ et al. Up-regulation of macrophage inflammatory protein-2 and complement 3A receptor by the trichothecenes deoxynivalenol and satratoxin G. 2003 Toxicology pmid:12604170
Zhou HR et al. Rapid, sequential activation of mitogen-activated protein kinases and transcription factors precedes proinflammatory cytokine mRNA expression in spleens of mice exposed to the trichothecene vomitoxin. 2003 Toxicol. Sci. pmid:12604842
Plattner RD and Maragos CM Determination of deoxynivalenol and nivalenol in corn and wheat by liquid chromatography with electrospray mass spectrometry. 2003 Jan-Feb J AOAC Int pmid:12607741
Lori GA et al. Fusarium graminearum and deoxynivalenol contamination in the durum wheat area of Argentina. 2003 Microbiol. Res. pmid:12608577
Zhou WC et al. Effect of individual Sumai 3 chromosomes on resistance to scab spread within spikes and deoxynivalenol accumulation within kernels in wheat. 2002 Hereditas pmid:12627831
Kos G et al. Development of a method for the determination of Fusarium fungi on corn using mid-infrared spectroscopy with attenuated total reflection and chemometrics. 2003 Anal. Chem. pmid:12641243
Tiemann U et al. Influence of the mycotoxins alpha- and beta-zearalenol and deoxynivalenol on the cell cycle of cultured porcine endometrial cells. 2003 Mar-Apr Reprod. Toxicol. pmid:12642154
Islam Z et al. Differential induction of glucocorticoid-dependent apoptosis in murine lymphoid subpopulations in vivo following coexposure to lipopolysaccharide and vomitoxin (deoxynivalenol). 2003 Toxicol. Appl. Pharmacol. pmid:12649039
Moon Y and Pestka JJ Cyclooxygenase-2 mediates interleukin-6 upregulation by vomitoxin (deoxynivalenol) in vitro and in vivo. 2003 Toxicol. Appl. Pharmacol. pmid:12649040
Moss MO Fusarial toxins: are they a cause for concern? 2003 Vet. J. pmid:12672361
Pestka JJ Deoxynivalenol-induced IgA production and IgA nephropathy-aberrant mucosal immune response with systemic repercussions. 2003 Toxicol. Lett. pmid:12676476
Nasir MS and Jolley ME Fluorescence polarization (FP) assays for the determination of grain mycotoxins (fumonisins, DON vomitoxin and aflatoxins). 2003 Comb. Chem. High Throughput Screen. pmid:12678705
Dänicke S et al. Effects of graded levels of Fusarium toxin-contaminated wheat and of a detoxifying agent in broiler diets on performance, nutrient digestibility and blood chemical parameters. 2003 Br. Poult. Sci. pmid:12737233
Wilbert FM and Kemmelmeier C Identification of deoxynivalenol, 3-acetyldeoxynivalenol, and zearalenone in galactose oxidase-producing isolates of Fusarium graminearum. 2003 J. Basic Microbiol. pmid:12746857
Kim HS et al. Polymorphism of trichothecene biosynthesis genes in deoxynivalenol- and nivalenol-producing Fusarium graminearum isolates. 2003 Mycol. Res. pmid:12747330
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Zhou HR et al. Role of double-stranded RNA-activated protein kinase R (PKR) in deoxynivalenol-induced ribotoxic stress response. 2003 Toxicol. Sci. pmid:12773753
Islam Z and Pestka JJ Role of IL-1(beta) in endotoxin potentiation of deoxynivalenol-induced corticosterone response and leukocyte apoptosis in mice. 2003 Toxicol. Sci. pmid:12773775
Weiss R et al. Improving methods of analysis for mycotoxins: molecularly imprinted polymers for deoxynivalenol and zearalenone. 2003 Food Addit Contam pmid:12775482
Rasmussen PH et al. Deoxynivalenol and other Fusarium toxins in wheat and rye flours on the Danish market. 2003 Food Addit Contam pmid:12775483
Omurtag GZ and BeyoÄŸlu D Occurrence of deoxynivalenol (vomitoxin) in processed cereals and pulses in Turkey. 2003 Food Addit Contam pmid:12775484
Lutz MP et al. Mycotoxigenic Fusarium and deoxynivalenol production repress chitinase gene expression in the biocontrol agent Trichoderma atroviride P1. 2003 Appl. Environ. Microbiol. pmid:12788701
Hope R and Magan N Two-dimensional environmental profiles of growth, deoxynivalenol and nivalenol production by Fusarium culmorum on a wheat-based substrate. 2003 Lett. Appl. Microbiol. pmid:12803560
Samar MM et al. Distribution of deoxynivalenol in wheat, wheat flour, bran, and gluten, and variability associated with the test procedure. 2003 May-Jun J AOAC Int pmid:12852575
Cirillo T et al. Natural co-occurrence of deoxynivalenol and fumonisins B1 and B2 in Italian marketed foodstuffs. 2003 Food Addit Contam pmid:12881130
Somers DJ et al. Molecular mapping of novel genes controlling Fusarium head blight resistance and deoxynivalenol accumulation in spring wheat. 2003 Genome pmid:12897863
House JD et al. Deoxynivalenol removal from barley intended as swine feed through the use of an abrasive pearling procedure. 2003 J. Agric. Food Chem. pmid:12903987
Krysińska-Traczyk E et al. [Filamentous fungi and mycotoxins as potential occupational risk factors among farmers harvesting various crops]. 2003 Med Pr pmid:12923995
Poppenberger B et al. Detoxification of the Fusarium mycotoxin deoxynivalenol by a UDP-glucosyltransferase from Arabidopsis thaliana. 2003 J. Biol. Chem. pmid:12970342
Park KJ et al. Natural occurrence of Fusarium mycotoxins of the 1990 barley crop in Korea. 1992 Nov-Dec Food Addit Contam pmid:1302203
Tüdös AJ et al. Rapid surface plasmon resonance-based inhibition assay of deoxynivalenol. 2003 J. Agric. Food Chem. pmid:13129282
Ayral AM et al. In vitro effect of diacetoxyscirpenol and deoxynivalenol on microbicidal activity of murine peritoneal macrophages. 1992 Mycopathologia pmid:1336129
Rizzo AF et al. The hemolytic activity of deoxynivalenol and T-2 toxin. 1992 Nat. Toxins pmid:1344904
Prelusky DB et al. Effect of deoxynivalenol on neurotransmitters in discrete regions of swine brain. 1992 Arch. Environ. Contam. Toxicol. pmid:1372799
Diekman MA and Green ML Mycotoxins and reproduction in domestic livestock. 1992 J. Anim. Sci. pmid:1388147
Gilbert J et al. Deoxynivalenol in wheat and maize flour reference materials. 1. An intercomparison of methods. 1992 Jan-Feb Food Addit Contam pmid:1397392
Rotter BA et al. Investigations in the use of mice exposed to mycotoxins as a model for growing pigs. 1992 J Toxicol Environ Health pmid:1404488
Bosch U and Mirocha CJ Toxin production by Fusarium species from sugar beets and natural occurrence of zearalenone in beets and beet fibers. 1992 Appl. Environ. Microbiol. pmid:1444361
Zielonka L et al. Influence of low doses of deoxynivalenol applied per os on chosen indexes of immune response in swine. 2003 Pol J Vet Sci pmid:14509371
Razzazi-Fazeli E et al. Simultaneous determination of major B-trichothecenes and the de-epoxy-metabolite of deoxynivalenol in pig urine and maize using high-performance liquid chromatography-mass spectrometry. 2003 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:14552813
Alexander NJ et al. Expression of Tri15 in Fusarium sporotrichioides. 2004 Curr. Genet. pmid:14624310
Usleber E et al. Studies on the application of enzyme immunoassays for the Fusarium mycotoxins deoxynivalenol, 3-acetyldeoxynivalenol, and zearalenone. 1992 Zentralblatt Veterinarmedizin Reihe B pmid:1462727
Minervini F et al. Toxicity and apoptosis induced by the mycotoxins nivalenol, deoxynivalenol and fumonisin B1 in a human erythroleukemia cell line. 2004 Toxicol In Vitro pmid:14630058
Chung YJ et al. Transcriptional and posttranscriptional roles for p38 mitogen-activated protein kinase in upregulation of TNF-alpha expression by deoxynivalenol (vomitoxin). 2003 Toxicol. Appl. Pharmacol. pmid:14644621
Froquet R et al. Do trichothecenes reduce viability of circulating blood cells and modify haemostasis parameters? 2003 Mycopathologia pmid:14682462