Vomitoxin

Vomitoxin is a lipid of Prenol Lipids (PR) class. Vomitoxin is associated with abnormalities such as Infection and Gastroenteritis. The involved functions are known as mRNA Expression, Inflammation, Transcription, Genetic, Protein Biosynthesis and Adverse effects. Vomitoxin often locates in Lymphoid Tissue, Immune system, Bone Marrow and Plasma membrane. The associated genes with Vomitoxin are IMPACT gene, HIST1H1C gene and RBM39 gene. The related experimental models are Mouse Model.

Cross Reference

Introduction

To understand associated biological information of Vomitoxin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Vomitoxin?

Vomitoxin is suspected in Infection, Gastroenteritis and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Vomitoxin

PubChem Associated disorders and diseases

What pathways are associated with Vomitoxin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Vomitoxin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Vomitoxin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Vomitoxin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Vomitoxin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Vomitoxin?

Mouse Model

Mouse Model are used in the study 'Dietary fish oil suppresses experimental immunoglobulin a nephropathy in mice.' (Pestka JJ et al., 2002).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with Vomitoxin

Download all related citations
Per page 10 20 50 100 | Total 1588
Authors Title Published Journal PubMed Link
Sulyok M et al. Development and validation of a liquid chromatography/tandem mass spectrometric method for the determination of 39 mycotoxins in wheat and maize. 2006 Rapid Commun. Mass Spectrom. pmid:16912987
Stroka J et al. Liquid chromatographic determination of deoxynivalenol in baby food and animal feed: interlaboratory study. 2006 Jul-Aug J AOAC Int pmid:16915838
Goyarts T et al. Effects of the Fusarium toxin deoxynivalenol from naturally contaminated wheat given subchronically or as one single dose on the in vivo protein synthesis of peripheral blood lymphocytes and plasma proteins in the pig. 2006 Food Chem. Toxicol. pmid:16950553
Drochner W et al. Subacute effects of moderate feed loads of isolated Fusarium toxin deoxynivalenol on selected parameters of metabolism in weaned growing piglets. 2006 J Anim Physiol Anim Nutr (Berl) pmid:16958800
Seeling K et al. Effects of Fusarium toxin-contaminated wheat and feed intake level on the biotransformation and carry-over of deoxynivalenol in dairy cows. 2006 Food Addit Contam pmid:16982523
Pan D et al. Deoxynivalenol in barley samples from Uruguay. 2007 Int. J. Food Microbiol. pmid:17067710
Häubl G et al. Characterization and application of isotope-substituted (13C15)-deoxynivalenol (DON) as an internal standard for the determination of DON. 2006 Food Addit Contam pmid:17071521
Li M et al. Deoxynivalenol exacerbates viral bronchopneumonia induced by respiratory reovirus infection. 2007 Toxicol. Sci. pmid:17090620
Kouadio JH et al. Effects of combinations of Fusarium mycotoxins on the inhibition of macromolecular synthesis, malondialdehyde levels, DNA methylation and fragmentation, and viability in Caco-2 cells. 2007 Toxicon pmid:17109910
Lippolis V et al. Optimization of a fluorescence polarization immunoassay for rapid quantification of deoxynivalenol in durum wheat-based products. 2006 J. Food Prot. pmid:17133816
Zhou BJ et al. [Effects of vitamin C on apoptosis and proliferation inhibition of human peripheral blood mononuclear cells induced by deoxynivalenol in vitro]. 2006 Zhonghua Yu Fang Yi Xue Za Zhi pmid:17166419
Zhou BJ et al. [Effects of vitamin C on the inhibition of human leucocyte antigen class I (HLA-I) expression of human peripheral blood mononuclear cells induced by deoxynivalenol in vitro]. 2006 Zhonghua Yu Fang Yi Xue Za Zhi pmid:17166420
Severino L et al. Mycotoxins nivalenol and deoxynivalenol differentially modulate cytokine mRNA expression in Jurkat T cells. 2006 Cytokine pmid:17166736
Awad WA et al. In vitro effects of deoxynivalenol on small intestinal D-glucose uptake and absorption of deoxynivalenol across the isolated jejunal epithelium of laying hens. 2007 Poult. Sci. pmid:17179409
Ngundi MM et al. Multiplexed detection of mycotoxins in foods with a regenerable array. 2006 J. Food Prot. pmid:17186679
Lucyshyn D et al. Cloning and characterization of the ribosomal protein L3 (RPL3) gene family from Triticum aestivum. 2007 Mol. Genet. Genomics pmid:17216491
Brenn-Struckhofova Z et al. Selective sample cleanup by reusable sol-gel immunoaffinity columns for determination of deoxynivalenol in food and feed samples. 2007 Anal. Chem. pmid:17222041
Krska R et al. Feasibility study for the production of certified calibrants for the determination of deoxynivalenol and other B-trichothecenes: intercomparison study. 2006 Nov-Dec J AOAC Int pmid:17225604
Dänicke S et al. On the interactions between Fusarium toxin-contaminated wheat and nonstarch polysaccharide hydrolyzing enzymes in diets of broilers on performance, intestinal viscosity, and carryover of deoxynivalenol. 2007 Poult. Sci. pmid:17234842
Ponts N et al. Exogenous H(2)O(2) and catalase treatments interfere with Tri genes expression in liquid cultures of Fusarium graminearum. 2007 FEBS Lett. pmid:17250833
Ansari KI et al. Retrotransposon and gene activation in wheat in response to mycotoxigenic and non-mycotoxigenic-associated Fusarium stress. 2007 Theor. Appl. Genet. pmid:17256175
Sabater-Vilar M et al. In vitro assessment of adsorbents aiming to prevent deoxynivalenol and zearalenone mycotoxicoses. 2007 Mycopathologia pmid:17294292
Grove JF The trichothecenes and their biosynthesis. 2007 Fortschr Chem Org Naturst pmid:17302179
He J et al. Purification of deoxynivalenol from Fusarium graminearum rice culture and mouldy corn by high-speed counter-current chromatography. 2007 J Chromatogr A pmid:17306807
Dänicke S et al. On the interactions between Fusarium toxin-contaminated wheat and non-starch-polysaccharide hydrolysing enzymes in turkey diets on performance, health and carry-over of deoxynivalenol and zearalenone. 2007 Br. Poult. Sci. pmid:17364539
Rasmussen PH et al. Annual variation of deoxynivalenol in Danish wheat flour 1998-2003 and estimated daily intake by the Danish population. 2007 Food Addit Contam pmid:17364935
Wollenhaupt K et al. Comparison of the molecular effects of the mycotoxins beta-zearalenol and deoxynivalenol in porcine endometrial cells--a review. 2007 Acta Vet. Hung. pmid:17385562
Dänicke S et al. On the transfer of the Fusarium toxins deoxynivalenol (DON) and zearalenone (ZON) from the sow to the full-term piglet during the last third of gestation. 2007 Food Chem. Toxicol. pmid:17399880
Baltriukiene D et al. Induction of apoptosis and activation of JNK and p38 MAPK pathways in deoxynivalenol-treated cell lines. 2007 Altern Lab Anim pmid:17411352
Masuda D et al. Phytotoxic effects of trichothecenes on the growth and morphology of Arabidopsis thaliana. 2007 J. Exp. Bot. pmid:17426057
Tiemann U et al. Changes in the spleen and liver of pregnant sows and full-term piglets after feeding diets naturally contaminated with deoxynivalenol and zearalenone. 2008 Vet. J. pmid:17434324
Sakai A et al. The activities of mycotoxins derived from Fusarium and related substances in a short-term transformation assay using v-Ha-ras-transfected BALB/3T3 cells (Bhas 42 cells). 2007 Mutat. Res. pmid:17499015
Wu X et al. Synthesis and characterization of deoxynivalenol glucuronide: its comparative immunotoxicity with deoxynivalenol. 2007 Food Chem. Toxicol. pmid:17507135
Ragab WS et al. Fate of deoxynivalenol in contaminated wheat grain during preparation of Egyptian 'balila'. 2007 Int J Food Sci Nutr pmid:17514535
Awad WA et al. Influence of deoxynivalenol on the D-glucose transport across the isolated epithelium of different intestinal segments of laying hens. 2007 J Anim Physiol Anim Nutr (Berl) pmid:17516937
Wang SH et al. Detection of deoxynivalenol based on a single-chain fragment variable of the antideoxynivalenol antibody. 2007 FEMS Microbiol. Lett. pmid:17521405
Videmann B et al. Epithelial transport of deoxynivalenol: involvement of human P-glycoprotein (ABCB1) and multidrug resistance-associated protein 2 (ABCC2). 2007 Food Chem. Toxicol. pmid:17543436
Goyarts T et al. On the transfer of the Fusarium toxins deoxynivalenol (DON) and zearalenone (ZON) from sows to their fetuses during days 35-70 of gestation. 2007 Toxicol. Lett. pmid:17544604
Krska R et al. Determination of molar absorptivity coefficients for major type-B trichothecenes and certification of calibrators for deoxynivalenol and nivalenol. 2007 Anal Bioanal Chem pmid:17551715
Cerveró MC et al. Determination of trichothecenes, zearalenone and zearalenols in commercially available corn-based foods in Spain. 2007 Rev Iberoam Micol pmid:17592894
Draeger R et al. Identification of QTLs for resistance to Fusarium head blight, DON accumulation and associated traits in the winter wheat variety Arina. 2007 Theor. Appl. Genet. pmid:17607557
Nduulu LM et al. Analysis of the chromosome 2(2H) region of barley associated with the correlated traits Fusarium head blight resistance and heading date. 2007 Theor. Appl. Genet. pmid:17609926
Harcz P et al. Intake of ochratoxin A and deoxynivalenol through beer consumption in Belgium. 2007 Food Addit Contam pmid:17613079
Gray JS and Pestka JJ Transcriptional regulation of deoxynivalenol-induced IL-8 expression in human monocytes. 2007 Toxicol. Sci. pmid:17636245
Malekinejad H et al. Exposure of oocytes to the Fusarium toxins zearalenone and deoxynivalenol causes aneuploidy and abnormal embryo development in pigs. 2007 Biol. Reprod. pmid:17652666
Hunder G et al. Influence of subchronic exposure to low dietary deoxynivalenol, a trichothecene mycotoxin, on intestinal absorption of nutrients in mice. 1991 Food Chem. Toxicol. pmid:1765325
Mankeviciene A et al. Fusarium mycotoxins in Lithuanian cereals from the 2004-2005 harvests. 2007 Ann Agric Environ Med pmid:17655186
Krysińska-Traczyk E et al. Levels of fungi and mycotoxins in the samples of grain and grain dust collected from five various cereal crops in eastern Poland. 2007 Ann Agric Environ Med pmid:17655194
Ranzenigo G et al. Effects of Fusarium mycotoxins on steroid production by porcine granulosa cells. 2008 Anim. Reprod. Sci. pmid:17656051
Stepanik T et al. Effects of electron beam irradiation on deoxynivalenol levels in distillers dried grain and solubles and in production intermediates. 2007 Food Addit Contam pmid:17691014
Fomenko VN et al. [Changes in the hemostatic system after administration of the mycotoxin deoxynivalenol (vomitoxin) to rhesus monkeys]. 1991 Gematol Transfuziol pmid:1769503
Jurjevic Z et al. Changes in fungi and mycotoxins in pearl millet under controlled storage conditions. 2007 Mycopathologia pmid:17701446
Beyer M et al. Estimating mycotoxin contents of Fusarium-damaged winter wheat kernels. 2007 Int. J. Food Microbiol. pmid:17706313
Moon Y et al. Modulation of early growth response gene 1 and interleukin-8 expression by ribotoxin deoxynivalenol (vomitoxin) via ERK1/2 in human epithelial intestine 407 cells. 2007 Biochem. Biophys. Res. Commun. pmid:17707346
Yuen GY and Schoneweis SD Strategies for managing Fusarium head blight and deoxynivalenol accumulation in wheat. 2007 Int. J. Food Microbiol. pmid:17716767
Zhang JB et al. Determination of the trichothecene mycotoxin chemotypes and associated geographical distribution and phylogenetic species of the Fusarium graminearum clade from China. 2007 Mycol. Res. pmid:17716884
Jiang GL et al. QTL analysis of resistance to Fusarium head blight in the novel wheat germplasm CJ 9306. II. Resistance to deoxynivalenol accumulation and grain yield loss. 2007 Theor. Appl. Genet. pmid:17726598
Döll S et al. Practically relevant concentrations of deoxynivalenol in diets for growing-finishing pigs offered as mash or pellets. 2007 Arch Anim Nutr pmid:17760303
Dänicke S et al. On the specific and unspecific effects of a polymeric glucomannan mycotoxin adsorbent on piglets when fed with uncontaminated or with Fusarium toxins contaminated diets. 2007 Arch Anim Nutr pmid:17760304
Königs M et al. Cytotoxicity, metabolism and cellular uptake of the mycotoxin deoxynivalenol in human proximal tubule cells and lung fibroblasts in primary culture. 2007 Toxicology pmid:17825972
Moon Y et al. Toxic alterations in chick embryonic liver and spleen by acute exposure to Fusarium-producing mycotoxin deoxynivalenol. 2007 Biol. Pharm. Bull. pmid:17827746
Lattanzio VM et al. Simultaneous determination of aflatoxins, ochratoxin A and Fusarium toxins in maize by liquid chromatography/tandem mass spectrometry after multitoxin immunoaffinity cleanup. 2007 Rapid Commun. Mass Spectrom. pmid:17828806
Gutzwiller A et al. Effects of Fusarium toxins on growth, humoral immune response and internal organs in weaner pigs, and the efficacy of apple pomace as an antidote. 2007 J Anim Physiol Anim Nutr (Berl) pmid:17845251
Bimczok D et al. The Fusarium toxin deoxynivalenol disrupts phenotype and function of monocyte-derived dendritic cells in vivo and in vitro. 2007 Immunobiology pmid:17869643
Rossi V et al. Assessment of Fusarium infection in wheat heads using a quantitative polymerase chain reaction (qPCR) assay. 2007 Food Addit Contam pmid:17886184
Schaafsma AW and Hooker DC Climatic models to predict occurrence of Fusarium toxins in wheat and maize. 2007 Int. J. Food Microbiol. pmid:17900733
Lattanzio VM et al. Determination of trichothecenes in cereals and cereal-based products by liquid chromatography-tandem mass spectrometry. 2008 Food Addit Contam Part A Chem Anal Control Expo Risk Assess pmid:17906997
Scudamore KA et al. Occurrence and fate of Fusarium mycotoxins during commercial processing of oats in the UK. 2007 Food Addit Contam pmid:17906998
Tanaka K et al. Mycotoxins in rice. 2007 Int. J. Food Microbiol. pmid:17913273
Kolosova AY et al. Development of a colloidal gold-based lateral-flow immunoassay for the rapid simultaneous detection of zearalenone and deoxynivalenol. 2007 Anal Bioanal Chem pmid:17922115
Garvey GS et al. Structural and functional characterization of the TRI101 trichothecene 3-O-acetyltransferase from Fusarium sporotrichioides and Fusarium graminearum: kinetic insights to combating Fusarium head blight. 2008 J. Biol. Chem. pmid:17923480
Turner PC et al. Dietary wheat reduction decreases the level of urinary deoxynivalenol in UK adults. 2008 J Expo Sci Environ Epidemiol pmid:17940556
Tutel'ian VA et al. [A method of determining the levels of deoxynivalenol (vomitoxin) and its metabolites]. 1991 Sep-Oct Vopr Pitan pmid:1796578
Zhou B et al. Doehlert matrix design for optimization of the determination of bound deoxynivalenol in barley grain with trifluoroacetic acid (TFA). 2007 J. Agric. Food Chem. pmid:18004804
González Pereyra ML et al. Fungi and selected mycotoxins from pre- and postfermented corn silage. 2008 J. Appl. Microbiol. pmid:18005347
Yang H et al. Ribotoxic mycotoxin deoxynivalenol induces G2/M cell cycle arrest via p21Cip/WAF1 mRNA stabilization in human epithelial cells. 2008 Toxicology pmid:18006205
Park JC et al. Survey of the presence of the Fusarium mycotoxins nivalenol, deoxynivalenol and T-2 toxin in Korean cereals of the 1989 harvest. 1991 Jul-Aug Food Addit Contam pmid:1806393
Tutel'ian VA et al. [Embryotoxic effects of deoxynivalenol mycotoxin (vomitoxin) in rats]. 1991 Gig Sanit pmid:1806423
Kallela K et al. Effect of germination on vomitoxin level in grain. 1991 Acta Vet. Scand. pmid:1818507
Turner PC et al. Urinary deoxynivalenol is correlated with cereal intake in individuals from the United kingdom. 2008 Environ. Health Perspect. pmid:18197294
Bucheli TD et al. Fusarium mycotoxins: overlooked aquatic micropollutants? 2008 J. Agric. Food Chem. pmid:18197623
Abolmaali S et al. Engineered bakers yeast as a sensitive bioassay indicator organism for the trichothecene toxin deoxynivalenol. 2008 J. Microbiol. Methods pmid:18243380
Russell L et al. Incidence of molds and mycotoxins in commercial animal feed mills in seven midwestern states, 1988-1989. 1991 J. Anim. Sci. pmid:1825995
Pascale M et al. Use of itaconic acid-based polymers for solid-phase extraction of deoxynivalenol and application to pasta analysis. 2008 Anal. Chim. Acta pmid:18261508
González HH et al. Trichothecenes and mycoflora in wheat harvested in nine locations in Buenos Aires province, Argentina. 2008 Mycopathologia pmid:18266077
Abouzied MM et al. Immunochemical assessment of mycotoxins in 1989 grain foods: evidence for deoxynivalenol (vomitoxin) contamination. 1991 Appl. Environ. Microbiol. pmid:1828138
Chen F et al. The combination of deoxynivalenol and zearalenone at permitted feed concentrations causes serious physiological effects in young pigs. 2008 J. Vet. Sci. pmid:18296887
Sahu SC et al. Rat liver clone-9 cells in culture as a model for screening hepatotoxic potential of food-related products: hepatotoxicity of deoxynivalenol. 2008 J Appl Toxicol pmid:18300328
Fredlund E et al. Method evaluation of Fusarium DNA extraction from mycelia and wheat for down-stream real-time PCR quantification and correlation to mycotoxin levels. 2008 J. Microbiol. Methods pmid:18304664
Maresca M et al. Both direct and indirect effects account for the pro-inflammatory activity of enteropathogenic mycotoxins on the human intestinal epithelium: stimulation of interleukin-8 secretion, potentiation of interleukin-1beta effect and increase in the transepithelial passage of commensal bacteria. 2008 Toxicol. Appl. Pharmacol. pmid:18308354
Scudamore KA et al. Fate of the fusarium mycotoxins, deoxynivalenol, nivalenol and zearalenone, during extrusion of wholemeal wheat grain. 2008 Food Addit Contam Part A Chem Anal Control Expo Risk Assess pmid:18311623
Roscoe V et al. Mycotoxins in breakfast cereals from the Canadian retail market: a 3-year survey. 2008 Food Addit Contam Part A Chem Anal Control Expo Risk Assess pmid:18311625
Pinton P et al. Ingestion of deoxynivalenol (DON) contaminated feed alters the pig vaccinal immune responses. 2008 Toxicol. Lett. pmid:18329193
Dong W et al. Quantitative assessment of mesangial immunoglobulin A (IgA) accumulation, elevated circulating IgA immune complexes, and hematuria during vomitoxin-induced IgA nephropathy. 1991 Fundam Appl Toxicol pmid:1833256
Lazo RF and Sierra G [Mycotoxin research in humans]. 2008 Rev Iberoam Micol pmid:18338920
Turner PC et al. Lactobacillus rhamnosus strain GG restores alkaline phosphatase activity in differentiating Caco-2 cells dosed with the potent mycotoxin deoxynivalenol. 2008 Food Chem. Toxicol. pmid:18343010
Van De Walle J et al. Influence of deoxynivalenol on NF-kappaB activation and IL-8 secretion in human intestinal Caco-2 cells. 2008 Toxicol. Lett. pmid:18343055
Pestka JJ et al. Immunochemical assessment of deoxynivalenol tissue distribution following oral exposure in the mouse. 2008 Toxicol. Lett. pmid:18395371
Amuzie CJ et al. Tissue distribution and proinflammatory cytokine induction by the trichothecene deoxynivalenol in the mouse: comparison of nasal vs. oral exposure. 2008 Toxicology pmid:18433975
Ruprich J and Ostrý V Immunochemical methods in health risk assessment: cross reactivity of antibodies against mycotoxin deoxynivalenol with deoxynivalenol-3-glucoside. 2008 Cent. Eur. J. Public Health pmid:18459478