| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Esophageal Neoplasms | D004938 | 20 associated lipids |
| Precancerous Conditions | D011230 | 48 associated lipids |
| Stomach Neoplasms | D013274 | 24 associated lipids |
| Hematuria | D006417 | 13 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
| Obesity | D009765 | 29 associated lipids |
Vomitoxin
Vomitoxin is a lipid of Prenol Lipids (PR) class. Vomitoxin is associated with abnormalities such as Infection and Gastroenteritis. The involved functions are known as mRNA Expression, Inflammation, Transcription, Genetic, Protein Biosynthesis and Adverse effects. Vomitoxin often locates in Lymphoid Tissue, Immune system, Bone Marrow and Plasma membrane. The associated genes with Vomitoxin are IMPACT gene, HIST1H1C gene and RBM39 gene. The related experimental models are Mouse Model.
Cross Reference
Introduction
To understand associated biological information of Vomitoxin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Vomitoxin?
Vomitoxin is suspected in Infection, Gastroenteritis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Vomitoxin
PubChem Associated disorders and diseases
What pathways are associated with Vomitoxin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Vomitoxin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Vomitoxin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Vomitoxin?
There are no associated biomedical information in the current reference collection.
What genes are associated with Vomitoxin?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Vomitoxin?
Mouse Model
Mouse Model are used in the study 'Dietary fish oil suppresses experimental immunoglobulin a nephropathy in mice.' (Pestka JJ et al., 2002).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Vomitoxin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid: | ||||
| Kasuga F et al. | In vitro effect of deoxynivalenol on the differentiation of human colonic cell lines Caco-2 and T84. | 1998 | Mycopathologia | pmid:10052164 |
| Charoenpornsook K et al. | The effects of four mycotoxins on the mitogen stimulated proliferation of bovine peripheral blood mononuclear cells in vitro. | 1998 | Mycopathologia | pmid:10205890 |
| Hughes DM et al. | Overt signs of toxicity to dogs and cats of dietary deoxynivalenol. | 1999 | J. Anim. Sci. | pmid:10229366 |
| Zhou HR et al. | Amplified proinflammatory cytokine expression and toxicity in mice coexposed to lipopolysaccharide and the trichothecene vomitoxin (deoxynivalenol). | 1999 | J. Toxicol. Environ. Health Part A | pmid:10344227 |
| Groves FD et al. | Fusarium mycotoxins in corn and corn products in a high-risk area for gastric cancer in Shandong Province, China. | 1999 May-Jun | J AOAC Int | pmid:10367384 |
| Banotai C et al. | Effects of intermittent vomitoxin exposure on body weight, immunoglobulin levels and haematuria in the B6C3F1 mouse. | 1999 | Food Chem. Toxicol. | pmid:10418952 |
| Yuan Q et al. | Identification of mimotope peptides which bind to the mycotoxin deoxynivalenol-specific monoclonal antibody. | 1999 | Appl. Environ. Microbiol. | pmid:10427007 |
| Banotai C et al. | Effects of vomitoxin ingestion on murine models for systemic lupus erythematosus. | 1999 | Food Chem. Toxicol. | pmid:10456682 |
| Wolf-Hall CE et al. | Stability of deoxynivalenol in heat-treated foods. | 1999 | J. Food Prot. | pmid:10456755 |
| Thuvander A et al. | In vitro exposure of human lymphocytes to trichothecenes: individual variation in sensitivity and effects of combined exposure on lymphocyte function. | 1999 | Food Chem. Toxicol. | pmid:10478832 |
| González HH et al. | Relationship between Fusarium graminearum and Alternaria alternata contamination and deoxynivalenol occurrence on Argentinian durum wheat. | 1998-1999 | Mycopathologia | pmid:10481289 |
| Langseth W et al. | Mycotoxin production and cytotoxicity of Fusarium strains isolated from Norwegian cereals. | 1998-1999 | Mycopathologia | pmid:10481290 |
| Wetter MT et al. | Occurrence and distribution of Fusarium graminearum and deoxynivalenol in sweet corn ears. | 1999 | Food Addit Contam | pmid:10492704 |
| Lee MG et al. | Effects of satratoxins and other macrocyclic trichothecenes on IL-2 production and viability of EL-4 thymoma cells. | 1999 | J. Toxicol. Environ. Health Part A | pmid:10494915 |
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| Cahill LM et al. | Quantification of deoxynivalenol in wheat using an immunoaffinity column and liquid chromatography. | 1999 | J Chromatogr A | pmid:10563412 |
| Sprando RL et al. | The effect of vomitoxin (Deoxnivalenol) on testicular morphology, testicular spermatid counts and epididymal sperm counts in IL-6KO [B6129-IL6 [TmlKopf] (IL-6 gene deficient)] and WT [B6129F2 (wild type to B6129-IL6 with an intact IL-6 gene)] mice. | 1999 | Food Chem. Toxicol. | pmid:10566878 |
| Accerbi M et al. | Utilization of highly deoxynivalenol-contaminated wheat via extrusion processing. | 1999 | J. Food Prot. | pmid:10606158 |
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| Zhou HR et al. | Lipopolysaccharide and the trichothecene vomitoxin (deoxynivalenol) synergistically induce apoptosis in murine lymphoid organs. | 2000 | Toxicol. Sci. | pmid:10696773 |
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| Rimando AM and Porter JK | Effects of Fusarium mycotoxins on levels of serotonin, melatonin, and 5-hydroxytryptophan in pineal cell cultures. | 1999 | Adv. Exp. Med. Biol. | pmid:10721085 |
| Boeira LS et al. | The effect of combinations of Fusarium mycotoxins (deoxynivalenol, zearalenone and fumonisin B1) on growth of brewing yeasts. | 2000 | J. Appl. Microbiol. | pmid:10747219 |
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| Wuchiyama J et al. | A trichothecene efflux pump encoded by Tri102 in the biosynthesis gene cluster of Fusarium graminearum. | 2000 | J. Antibiot. | pmid:10805582 |
| Schollenberger M et al. | A survey of Fusarium toxins in cereal-based foods marketed in an area of southwest Germany. | 1999 | Mycopathologia | pmid:10872516 |
| May HD et al. | Effects of the Fusarium spp. mycotoxins fusaric acid and deoxynivalenol on the growth of Ruminococcus albus and Methanobrevibacter ruminantium. | 2000 | Can. J. Microbiol. | pmid:10941514 |
| Pestka JJ and Zhou HR | Interleukin-6-deficient mice refractory to IgA dysregulation but not anorexia induction by vomitoxin (deoxynivalenol) ingestion. | 2000 | Food Chem. Toxicol. | pmid:10942317 |
| Reid LM et al. | Pre-harvest accumulation of deoxynivalenol in sweet corn ears inoculated with Fusarium graminearum. | 2000 | Food Addit Contam | pmid:11027030 |
| Widestrand J et al. | Cytotoxicity of four trichothecenes evaluated by three colorimetric bioassays. | 1999 | Mycopathologia | pmid:11040865 |
| Langseth W and Rundberget T | The occurrence of HT-2 toxin and other trichothecenes in Norwegian cereals. | 1999 | Mycopathologia | pmid:11040866 |
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| Freese L et al. | Variability of deoxynivalenol measurements in barley. | 2000 Sep-Oct | J AOAC Int | pmid:11048870 |
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| Yoshizawa T | Chromatographic methods for trichothecenes. | 2001 | Methods Mol. Biol. | pmid:11050998 |
| Rafai P et al. | Evaluation of mycotoxin-contaminated cereals for their use in animal feeds in Hungary. | 2000 | Food Addit Contam | pmid:11091794 |
| Plattner RD | HPLC/MS analysis of fusarium mycotoxins, fumonisins and deoxynivalenol. | 1999 | Nat. Toxins | pmid:11122531 |
| Cooney JM et al. | Impact of competitive fungi on Trichothecene production by Fusarium graminearum. | 2001 | J. Agric. Food Chem. | pmid:11170621 |
| Schneider L et al. | An enzyme linked immunoassay for the determination of deoxynivalenol in wheat based on chicken egg yolk antibodies. | 2000 | Fresenius J Anal Chem | pmid:11227446 |
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| Edwards SG et al. | Quantification of trichothecene-producing Fusarium species in harvested grain by competitive PCR to determine efficacies of fungicides against Fusarium head blight of winter wheat. | 2001 | Appl. Environ. Microbiol. | pmid:11282607 |
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| Wong S et al. | Superinduction of TNF-alpha and IL-6 in macrophages by vomitoxin (deoxynivalenol) modulated by mRNA stabilization. | 2001 | Toxicology | pmid:11295263 |
| Froquet R et al. | Trichothecene toxicity on human megakaryocyte progenitors (CFU-MK). | 2001 | Hum Exp Toxicol | pmid:11327514 |
| Brown DW et al. | A genetic and biochemical approach to study trichothecene diversity in Fusarium sporotrichioides and Fusarium graminearum. | 2001 | Fungal Genet. Biol. | pmid:11352533 |
| Fazekas B et al. | Natural deoxynivalenol (DON) contamination of wheat samples grown in 1998 as determined by high-performance liquid chromatography. | 2000 | Acta Vet. Hung. | pmid:11402697 |
| Mateo JJ et al. | Critical study of and improvements in chromatographic methods for the analysis of type B trichothecenes. | 2001 | J Chromatogr A | pmid:11403460 |
| Lee T et al. | Identification of deoxynivalenol- and nivalenol-producing chemotypes of Gibberella zeae by using PCR. | 2001 | Appl. Environ. Microbiol. | pmid:11425709 |
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| Cazzaniga D et al. | Mycotoxins inactivation by extrusion cooking of corn flour. | 2001 | Lett. Appl. Microbiol. | pmid:11472523 |
| Debouck C et al. | Skeletal deformities induced by the intraperitoneal administration of deoxynivalenol (vomitoxin) in mice. | 2001 | Int Orthop | pmid:11482540 |
| Samar MM et al. | Effect of fermentation on naturally occurring deoxynivalenol (DON) in Argentinean bread processing technology. | 2001 | Food Addit Contam | pmid:11665728 |
| Widestrand J and Pettersson H | Effect of time, temperature and solvent on the stability of T-2 toxin, HT-2 toxin, deoxynivalenol and nivalenol calibrants. | 2001 | Food Addit Contam | pmid:11665740 |
| Langseth W et al. | Production of culmorin compounds and other secondary metabolites by Fusarium culmorum and F. graminearum strains isolated from Norwegian cereals. | 2001 | Mycopathologia | pmid:11694092 |
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| Ghebremeskel M and Langseth W | The occurrence of culmorin and hydroxy-culmorins in cereals. | 2001 | Mycopathologia | pmid:11761144 |
| Sugita-Konishi Y and Pestka JJ | Differential upregulation of TNF-alpha, IL-6, and IL-8 production by deoxynivalenol (vomitoxin) and other 8-ketotrichothecenes in a human macrophage model. | 2001 | J. Toxicol. Environ. Health Part A | pmid:11766169 |
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| Pestka JJ et al. | Dietary fish oil suppresses experimental immunoglobulin a nephropathy in mice. | 2002 | J. Nutr. | pmid:11823588 |
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| Yang GH and Pestka JJ | Vomitoxin (deoxynivalenol)-mediated inhibition of nuclear protein binding to NRE-A, an IL-2 promoter negative regulatory element, in EL-4 cells. | 2002 | Toxicology | pmid:11893416 |
| Maragos CM and Plattner RD | Rapid fluorescence polarization immunoassay for the mycotoxin deoxynivalenol in wheat. | 2002 | J. Agric. Food Chem. | pmid:11902919 |
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| Lee T et al. | Tri13 and Tri7 determine deoxynivalenol- and nivalenol-producing chemotypes of Gibberella zeae. | 2002 | Appl. Environ. Microbiol. | pmid:11976083 |
| Bai GH et al. | Deoxynivalenol-nonproducing fusarium graminearum causes initial infection, but does not cause disease spread in wheat spikes. | 2002 | Mycopathologia | pmid:12000132 |
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| Swamy HV et al. | Effects of feeding blends of grains naturally contaminated with Fusarium mycotoxins on production and metabolism in broilers. | 2002 | Poult. Sci. | pmid:12162357 |
| Wong SS et al. | Effects of vomitoxin (deoxynivalenol) on the binding of transcription factors AP-1, NF-kappaB, and NF-IL6 in raw 264.7 macrophage cells. | 2002 | J. Toxicol. Environ. Health Part A | pmid:12167214 |
| Pestka JJ and Zhou HR | Effects of tumor necrosis factor type 1 and 2 receptor deficiencies on anorexia, growth and IgA dysregulation in mice exposed to the trichothecene vomitoxin. | 2002 | Food Chem. Toxicol. | pmid:12176089 |
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| Moon Y and Pestka JJ | Vomitoxin-induced cyclooxygenase-2 gene expression in macrophages mediated by activation of ERK and p38 but not JNK mitogen-activated protein kinases. | 2002 | Toxicol. Sci. | pmid:12377986 |
| Bakan B et al. | Identification by PCR of Fusarium culmorum strains producing large and small amounts of deoxynivalenol. | 2002 | Appl. Environ. Microbiol. | pmid:12406740 |
| Alm H et al. | The influence of the mycotoxins deoxynivalenol and zearalenol on in vitro maturation of pig oocytes and in vitro culture of pig zygotes. | 2002 | Toxicol In Vitro | pmid:12423645 |
| Dänicke S et al. | Effect of addition of a detoxifying agent to laying hen diets containing uncontaminated or Fusarium toxin-contaminated maize on performance of hens and on carryover of zearalenone. | 2002 | Poult. Sci. | pmid:12455595 |
| Leblanc JC et al. | Simulation of the exposure to deoxynivalenol of French consumers of organic and conventional foodstuffs. | 2002 | Regul. Toxicol. Pharmacol. | pmid:12460749 |
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| Rupp HS | Determination of deoxynivalenol in whole wheat flour and wheat bran. | 2002 Nov-Dec | J AOAC Int | pmid:12477199 |
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