Vomitoxin

Vomitoxin is a lipid of Prenol Lipids (PR) class. Vomitoxin is associated with abnormalities such as Infection and Gastroenteritis. The involved functions are known as mRNA Expression, Inflammation, Transcription, Genetic, Protein Biosynthesis and Adverse effects. Vomitoxin often locates in Lymphoid Tissue, Immune system, Bone Marrow and Plasma membrane. The associated genes with Vomitoxin are IMPACT gene, HIST1H1C gene and RBM39 gene. The related experimental models are Mouse Model.

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Introduction

To understand associated biological information of Vomitoxin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Vomitoxin?

Vomitoxin is suspected in Infection, Gastroenteritis and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Vomitoxin

PubChem Associated disorders and diseases

What pathways are associated with Vomitoxin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Vomitoxin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Vomitoxin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Vomitoxin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Vomitoxin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Vomitoxin?

Mouse Model

Mouse Model are used in the study 'Dietary fish oil suppresses experimental immunoglobulin a nephropathy in mice.' (Pestka JJ et al., 2002).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Vomitoxin

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Authors Title Published Journal PubMed Link
pmid:
Kasuga F et al. In vitro effect of deoxynivalenol on the differentiation of human colonic cell lines Caco-2 and T84. 1998 Mycopathologia pmid:10052164
Charoenpornsook K et al. The effects of four mycotoxins on the mitogen stimulated proliferation of bovine peripheral blood mononuclear cells in vitro. 1998 Mycopathologia pmid:10205890
Hughes DM et al. Overt signs of toxicity to dogs and cats of dietary deoxynivalenol. 1999 J. Anim. Sci. pmid:10229366
Zhou HR et al. Amplified proinflammatory cytokine expression and toxicity in mice coexposed to lipopolysaccharide and the trichothecene vomitoxin (deoxynivalenol). 1999 J. Toxicol. Environ. Health Part A pmid:10344227
Groves FD et al. Fusarium mycotoxins in corn and corn products in a high-risk area for gastric cancer in Shandong Province, China. 1999 May-Jun J AOAC Int pmid:10367384
Banotai C et al. Effects of intermittent vomitoxin exposure on body weight, immunoglobulin levels and haematuria in the B6C3F1 mouse. 1999 Food Chem. Toxicol. pmid:10418952
Yuan Q et al. Identification of mimotope peptides which bind to the mycotoxin deoxynivalenol-specific monoclonal antibody. 1999 Appl. Environ. Microbiol. pmid:10427007
Banotai C et al. Effects of vomitoxin ingestion on murine models for systemic lupus erythematosus. 1999 Food Chem. Toxicol. pmid:10456682
Wolf-Hall CE et al. Stability of deoxynivalenol in heat-treated foods. 1999 J. Food Prot. pmid:10456755
Thuvander A et al. In vitro exposure of human lymphocytes to trichothecenes: individual variation in sensitivity and effects of combined exposure on lymphocyte function. 1999 Food Chem. Toxicol. pmid:10478832
González HH et al. Relationship between Fusarium graminearum and Alternaria alternata contamination and deoxynivalenol occurrence on Argentinian durum wheat. 1998-1999 Mycopathologia pmid:10481289
Langseth W et al. Mycotoxin production and cytotoxicity of Fusarium strains isolated from Norwegian cereals. 1998-1999 Mycopathologia pmid:10481290
Wetter MT et al. Occurrence and distribution of Fusarium graminearum and deoxynivalenol in sweet corn ears. 1999 Food Addit Contam pmid:10492704
Lee MG et al. Effects of satratoxins and other macrocyclic trichothecenes on IL-2 production and viability of EL-4 thymoma cells. 1999 J. Toxicol. Environ. Health Part A pmid:10494915
Razzazi-Fazeli E et al. Determination of nivalenol and deoxynivalenol in wheat using liquid chromatography-mass spectrometry with negative ion atmospheric pressure chemical ionisation. 1999 J Chromatogr A pmid:10497927
Hsueh CC et al. Indirect electrochemical detection of type-B trichothecene mycotoxins. 1999 Anal. Chem. pmid:10500491
Janardhana GR et al. Mycotoxin contamination of maize grains grown in Karnataka (India). 1999 Food Chem. Toxicol. pmid:10506010
Cahill LM et al. Quantification of deoxynivalenol in wheat using an immunoaffinity column and liquid chromatography. 1999 J Chromatogr A pmid:10563412
Sprando RL et al. The effect of vomitoxin (Deoxnivalenol) on testicular morphology, testicular spermatid counts and epididymal sperm counts in IL-6KO [B6129-IL6 [TmlKopf] (IL-6 gene deficient)] and WT [B6129F2 (wild type to B6129-IL6 with an intact IL-6 gene)] mice. 1999 Food Chem. Toxicol. pmid:10566878
Accerbi M et al. Utilization of highly deoxynivalenol-contaminated wheat via extrusion processing. 1999 J. Food Prot. pmid:10606158
Yang GH et al. Down-regulation of the endoplasmic reticulum chaperone GRP78/BiP by vomitoxin (Deoxynivalenol). 2000 Toxicol. Appl. Pharmacol. pmid:10652249
Li S et al. Modulation of transcription factor AP-1 activity in murine EL-4 thymoma cells by vomitoxin (deoxynivalenol). 2000 Toxicol. Appl. Pharmacol. pmid:10662601
Zhou HR et al. Lipopolysaccharide and the trichothecene vomitoxin (deoxynivalenol) synergistically induce apoptosis in murine lymphoid organs. 2000 Toxicol. Sci. pmid:10696773
Johannisson A et al. Effects of four trichothecene mycotoxins on activation marker expression and cell proliferation of human lymphocytes in culture. 1999 Cell Biol. Toxicol. pmid:10696820
Desjardins AE et al. Fusarium species from nepalese rice and production of mycotoxins and gibberellic acid by selected species. 2000 Appl. Environ. Microbiol. pmid:10698766
Rimando AM and Porter JK Effects of Fusarium mycotoxins on levels of serotonin, melatonin, and 5-hydroxytryptophan in pineal cell cultures. 1999 Adv. Exp. Med. Biol. pmid:10721085
Boeira LS et al. The effect of combinations of Fusarium mycotoxins (deoxynivalenol, zearalenone and fumonisin B1) on growth of brewing yeasts. 2000 J. Appl. Microbiol. pmid:10747219
Yang GH et al. Apoptosis induction by the satratoxins and other trichothecene mycotoxins: relationship to ERK, p38 MAPK, and SAPK/JNK activation. 2000 Toxicol. Appl. Pharmacol. pmid:10764628
Wuchiyama J et al. A trichothecene efflux pump encoded by Tri102 in the biosynthesis gene cluster of Fusarium graminearum. 2000 J. Antibiot. pmid:10805582
Schollenberger M et al. A survey of Fusarium toxins in cereal-based foods marketed in an area of southwest Germany. 1999 Mycopathologia pmid:10872516
May HD et al. Effects of the Fusarium spp. mycotoxins fusaric acid and deoxynivalenol on the growth of Ruminococcus albus and Methanobrevibacter ruminantium. 2000 Can. J. Microbiol. pmid:10941514
Pestka JJ and Zhou HR Interleukin-6-deficient mice refractory to IgA dysregulation but not anorexia induction by vomitoxin (deoxynivalenol) ingestion. 2000 Food Chem. Toxicol. pmid:10942317
Reid LM et al. Pre-harvest accumulation of deoxynivalenol in sweet corn ears inoculated with Fusarium graminearum. 2000 Food Addit Contam pmid:11027030
Widestrand J et al. Cytotoxicity of four trichothecenes evaluated by three colorimetric bioassays. 1999 Mycopathologia pmid:11040865
Langseth W and Rundberget T The occurrence of HT-2 toxin and other trichothecenes in Norwegian cereals. 1999 Mycopathologia pmid:11040866
Moreno Contreras MC et al. [Determination of deoxynivalenol (DON) in wheat, barley and corn and its relationship with the levels of total molds, Fusarium spp., colonization percentage and water activity]. 2000 Arch Latinoam Nutr pmid:11048592
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Whitaker TB et al. Sampling, sample preparation, and analytical variability associated with testing wheat for deoxynivalenol. 2000 Sep-Oct J AOAC Int pmid:11048874
Malone B Solution fluorometric method for deoxynivalenol in grains. 2001 Methods Mol. Biol. pmid:11050997
Yoshizawa T Chromatographic methods for trichothecenes. 2001 Methods Mol. Biol. pmid:11050998
Rafai P et al. Evaluation of mycotoxin-contaminated cereals for their use in animal feeds in Hungary. 2000 Food Addit Contam pmid:11091794
Plattner RD HPLC/MS analysis of fusarium mycotoxins, fumonisins and deoxynivalenol. 1999 Nat. Toxins pmid:11122531
Cooney JM et al. Impact of competitive fungi on Trichothecene production by Fusarium graminearum. 2001 J. Agric. Food Chem. pmid:11170621
Schneider L et al. An enzyme linked immunoassay for the determination of deoxynivalenol in wheat based on chicken egg yolk antibodies. 2000 Fresenius J Anal Chem pmid:11227446
Grabarkiewicz-Szczesna J et al. Fusariotoxins in kernels of winter wheat cultivars field samples collected during 1993 in Poland. 2001 Nahrung pmid:11253636
Machado LC and Kemmelmeier C Identification of deoxynivalenol, 3-acetyldeoxynivalenol and zearalenone in the galactose oxidase-producing fungus Dactylium dendroides. 2001 Mycopathologia pmid:11265166
Birzele B et al. Deoxynivalenol and ochratoxin A in German wheat and changes of level in relation to storage parameters. 2000 Food Addit Contam pmid:11271837
Edwards SG et al. Quantification of trichothecene-producing Fusarium species in harvested grain by competitive PCR to determine efficacies of fungicides against Fusarium head blight of winter wheat. 2001 Appl. Environ. Microbiol. pmid:11282607
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