Vomitoxin

Vomitoxin is a lipid of Prenol Lipids (PR) class. Vomitoxin is associated with abnormalities such as Infection and Gastroenteritis. The involved functions are known as mRNA Expression, Inflammation, Transcription, Genetic, Protein Biosynthesis and Adverse effects. Vomitoxin often locates in Lymphoid Tissue, Immune system, Bone Marrow and Plasma membrane. The associated genes with Vomitoxin are IMPACT gene, HIST1H1C gene and RBM39 gene. The related experimental models are Mouse Model.

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Introduction

To understand associated biological information of Vomitoxin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Vomitoxin?

Vomitoxin is suspected in Infection, Gastroenteritis and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Vomitoxin

PubChem Associated disorders and diseases

What pathways are associated with Vomitoxin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Vomitoxin?

Related references are published most in these journals:

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What functions are associated with Vomitoxin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Vomitoxin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Vomitoxin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Vomitoxin?

Mouse Model

Mouse Model are used in the study 'Dietary fish oil suppresses experimental immunoglobulin a nephropathy in mice.' (Pestka JJ et al., 2002).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Vomitoxin

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Authors Title Published Journal PubMed Link
Sprando RL et al. The effect of vomitoxin (Deoxnivalenol) on testicular morphology, testicular spermatid counts and epididymal sperm counts in IL-6KO [B6129-IL6 [TmlKopf] (IL-6 gene deficient)] and WT [B6129F2 (wild type to B6129-IL6 with an intact IL-6 gene)] mice. 1999 Food Chem. Toxicol. pmid:10566878
Plattner RD HPLC/MS analysis of fusarium mycotoxins, fumonisins and deoxynivalenol. 1999 Nat. Toxins pmid:11122531
Widestrand J et al. Cytotoxicity of four trichothecenes evaluated by three colorimetric bioassays. 1999 Mycopathologia pmid:11040865
Banotai C et al. Effects of vomitoxin ingestion on murine models for systemic lupus erythematosus. 1999 Food Chem. Toxicol. pmid:10456682
Wolf-Hall CE et al. Stability of deoxynivalenol in heat-treated foods. 1999 J. Food Prot. pmid:10456755
Yuan Q et al. Identification of mimotope peptides which bind to the mycotoxin deoxynivalenol-specific monoclonal antibody. 1999 Appl. Environ. Microbiol. pmid:10427007
Zhou HR et al. Amplified proinflammatory cytokine expression and toxicity in mice coexposed to lipopolysaccharide and the trichothecene vomitoxin (deoxynivalenol). 1999 J. Toxicol. Environ. Health Part A pmid:10344227
González HH et al. Relationship between Fusarium graminearum and Alternaria alternata contamination and deoxynivalenol occurrence on Argentinian durum wheat. 1998-1999 Mycopathologia pmid:10481289
Langseth W et al. Mycotoxin production and cytotoxicity of Fusarium strains isolated from Norwegian cereals. 1998-1999 Mycopathologia pmid:10481290
Malone BR et al. One-step solid-phase extraction cleanup and fluorometric analysis of deoxynivalenol in grains. 1998 Mar-Apr J AOAC Int pmid:9549079
Walker F and Meier B Determination of the Fusarium mycotoxins nivalenol, deoxynivalenol, 3-acetyldeoxynivalenol, and 15-O-acetyl-4-deoxynivalenol in contaminated whole wheat flour by liquid chromatography with diode array detection and gas chromatography with electron capture detection. 1998 Jul-Aug J AOAC Int pmid:9680699
Trucksess MW et al. Determination of deoxynivalenol in white flour, whole wheat flour, and bran by solid-phase extraction/liquid chromatography: interlaboratory study. 1998 Jul-Aug J AOAC Int pmid:9680714
Wong SS et al. Modulation of IL-1beta, IL-6 and TNF-alpha secretion and mRNA expression by the trichothecene vomitoxin in the RAW 264.7 murine macrophage cell line. 1998 Food Chem. Toxicol. pmid:9662416
Abramson D et al. Relationships among deoxynivalenol, ergosterol and Fusarium exoantigens in Canadian hard and soft wheat. 1998 Int. J. Food Microbiol. pmid:9926999
Schaafsma AW et al. Analysis of Fusarium toxins in maize and wheat using thin layer chromatography. 1998 Mycopathologia pmid:9926423
Atroshi F et al. Effects of tamoxifen, melatonin, coenzyme Q10, and L-carnitine supplementation on bacterial growth in the presence of mycotoxins. 1998 Pharmacol. Res. pmid:9774492
Ji GE et al. Modulation of nitric oxide, hydrogen peroxide and cytokine production in a clonal macrophage model by the trichothecene vomitoxin (deoxynivalenol). 1998 Toxicology pmid:9570333
Yan D et al. Role of macrophages in elevated IgA and IL-6 production by Peyer's patch cultures following acute oral vomitoxin exposure. 1998 Toxicol. Appl. Pharmacol. pmid:9473534
Hart LP et al. Comparison of gas chromatography-electron capture and enzyme-linked immunosorbent assay for deoxynivalenol in milled fractions of naturally contaminated wheat. 1998 J. Food Prot. pmid:9874353
Charoenpornsook K et al. The effects of four mycotoxins on the mitogen stimulated proliferation of bovine peripheral blood mononuclear cells in vitro. 1998 Mycopathologia pmid:10205890
Perkowski J Distribution of deoxynivalenol in barley kernels infected by Fusarium. 1998 Nahrung pmid:9631371
Zhou HR et al. Induction of cytokine gene expression in mice after repeated and subchronic oral exposure to vomitoxin (Deoxynivalenol): differential toxin-induced hyporesponsiveness and recovery. 1998 Toxicol. Appl. Pharmacol. pmid:9707511
Beattie S et al. The effect of grain storage conditions on the viability of Fusarium and deoxynivalenol production in infested malting barley. 1998 J. Food Prot. pmid:9708261
Wolf CE and Bullerman LB Heat and pH alter the concentration of deoxynivalenol in an aqueous environment. 1998 J. Food Prot. pmid:9708313
Galvano F et al. Activated carbons: in vitro affinity for ochratoxin A and deoxynivalenol and relation of adsorption ability to physicochemical parameters. 1998 J. Food Prot. pmid:9709212
Kasuga F et al. In vitro effect of deoxynivalenol on the differentiation of human colonic cell lines Caco-2 and T84. 1998 Mycopathologia pmid:10052164
Yan D et al. Experimental murine IgA nephropathy following passive administration of vomitoxin-induced IgA monoclonal antibodies. 1998 Food Chem. Toxicol. pmid:9862652
Obol'skiÄ­ OL et al. [Effect of dietary selenium on the activity of UDP-glucuronosyltransferases and metabolism of mycotoxin deoxynivalenol in rats]. 1998 Vopr Pitan pmid:9825468
Ali-Vehmas T et al. Measurement of antibacterial activities of T-2 toxin, deoxynivalenol, ochratoxin A, aflatoxin B1 and fumonisin B1 using microtitration tray-based turbidimetric techniques. 1998 Zentralbl Veterinarmed A pmid:9838857
Krska R Performance of modern sample preparation techniques in the analysis of Fusarium mycotoxins in cereals. 1998 J Chromatogr A pmid:9718706
Harvey RB et al. Moniliformin from Fusarium fujikuroi culture material and deoxynivalenol from naturally contaminated wheat incorporated into diets of broiler chicks. 1997 Oct-Dec Avian Dis. pmid:9454932
Pacin AM et al. Natural occurrence of deoxynivalenol in wheat, wheat flour and bakery products in Argentina. 1997 May-Jun Food Addit Contam pmid:9205560
Miller JD and Ewen MA Toxic effects of deoxynivalenol on ribosomes and tissues of the spring wheat cultivars Frontana and Casavant. 1997 Nat. Toxins pmid:9615311
Hedman R and Pettersson H Transformation of nivalenol by gastrointestinal microbes. 1997 Arch Tierernahr pmid:9345596
Shima J et al. Novel detoxification of the trichothecene mycotoxin deoxynivalenol by a soil bacterium isolated by enrichment culture. 1997 Appl. Environ. Microbiol. pmid:9327545
Rio B et al. In vitro toxicity of trichothecenes on human erythroblastic progenitors. 1997 Hum Exp Toxicol pmid:9426370
Overnes G et al. Effects of diets with graded levels of naturally deoxynivalenol-contaminated oats on immune response in growing pigs. 1997 Zentralbl Veterinarmed A pmid:9465774
Li S et al. Superinduction of IL-2 gene expression by vomitoxin (deoxynivalenol) involves increased mRNA stability. 1997 Toxicol. Appl. Pharmacol. pmid:9439728
Prelusky DB et al. Effect of the appetite stimulant cyproheptadine on deoxynivalenol-induced reductions in feed consumption and weight gain in the mouse. 1997 J Environ Sci Health B pmid:9177014
Yan D et al. Potential role for IL-5 and IL-6 in enhanced IgA secretion by Peyer's patch cells isolated from mice acutely exposed to vomitoxin. 1997 Toxicology pmid:9274810
Kubena LF et al. Individual and combined effects of fumonisin B1 present in Fusarium moniliforme culture material and T-2 toxin or deoxynivalenol in broiler chicks. 1997 Poult. Sci. pmid:9276886
Johnson PJ et al. Effect of feeding deoxynivalenol (vomitoxin)-contaminated barley to horses. 1997 J. Vet. Diagn. Invest. pmid:9211250
Knasmüller S et al. Genotoxic effects of three Fusarium mycotoxins, fumonisin B1, moniliformin and vomitoxin in bacteria and in primary cultures of rat hepatocytes. 1997 Mutat. Res. pmid:9219547
Neira MS et al. The effects of bakery processing on natural deoxynivalenol contamination. 1997 Int. J. Food Microbiol. pmid:9237118
Zhou HR et al. Differential cytokine mRNA expression in mice after oral exposure to the trichothecene vomitoxin (deoxynivalenol): dose response and time course. 1997 Toxicol. Appl. Pharmacol. pmid:9194413
Lautraite S et al. In vitro toxicity induced by deoxynivalenol (DON) on human and rat granulomonocytic progenitors. 1997 Cell Biol. Toxicol. pmid:9088627
Dalcero A et al. Occurrence of deoxynivalenol and Fusarium graminearum in Argentinian wheat. 1997 Food Addit Contam pmid:9059578
Smith TK et al. Effect of feeding blends of Fusarium mycotoxin-contaminated grains containing deoxynivalenol and fusaric acid on growth and feed consumption of immature swine. 1997 J. Anim. Sci. pmid:9263067
Prelusky DB Effect of intraperitoneal infusion of deoxynivalenol on feed consumption and weight gain in the pig. 1997 Nat. Toxins pmid:9285917
Dalcero A et al. Mycoflora and incidence of aflatoxin B1, zearalenone and deoxynivalenol in poultry feeds in Argentina. 1997 Mycopathologia pmid:9368410
Aziz NH et al. Effect of gamma-irradiation on the natural occurrence of Fusarium mycotoxins in wheat, flour and bread. 1997 Nahrung pmid:9113669
Tacke BK and Casper HH Determination of deoxynivalenol in wheat, barley, and malt by column cleanup and gas chromatography with electron capture detection. 1996 Mar-Apr J AOAC Int pmid:8920135
Trucksess MW et al. Determination and survey of deoxynivalenol in white flour, whole wheat flour, and bran. 1996 Jul-Aug J AOAC Int pmid:8757447
León-S FE et al. Mycotoxins in myelopathies of man. 1996 Lancet pmid:8855894
Rotter BA et al. Toxicology of deoxynivalenol (vomitoxin). 1996 J Toxicol Environ Health pmid:8637056
Boston S et al. Consumption of deoxynivalenol-contaminated wheat by mallard ducks under experimental conditions. 1996 J. Wildl. Dis. pmid:8627931
Prelusky DB A study on the effect of deoxynivalenol on serotonin receptor binding in pig brain membranes. 1996 J Environ Sci Health B pmid:8751451
Ouyang YL et al. Vomitoxin-mediated IL-2, IL-4, and IL-5 superinduction in murine CD4+ T cells stimulated with phorbol ester calcium ionophore: relation to kinetics of proliferation. 1996 Toxicol. Appl. Pharmacol. pmid:8658534
Ouyang YL et al. Effects of vomitoxin (deoxynivalenol) on transcription factor NF-kappa B/Rel binding activity in murine EL-4 thymoma and primary CD4+ T cells. 1996 Toxicol. Appl. Pharmacol. pmid:8887449
Rotter BA et al. The role of tryptophan in DON-induced feed rejection. 1996 J Environ Sci Health B pmid:8896360
González HH et al. Deoxynivalenol and contaminant mycoflora in freshly harvested Argentinian wheat in 1993. 1996 Mycopathologia pmid:9091829
Snijders CH et al. Analysis of Fusarium causing dermal toxicosis in marram grass planters. 1996 Mycopathologia pmid:9063007
O'Neill K et al. The influence of gamma radiation and substrate on mycotoxin production by Fusarium culmorum IMI 309344. 1996 J. Appl. Bacteriol. pmid:8939030
Iverson F et al. Chronic feeding study of deoxynivalenol in B6C3F1 male and female mice. 1995-1996 Teratog., Carcinog. Mutagen. pmid:8732880
Yoshizawa T and Jin YZ Natural occurrence of acetylated derivatives of deoxynivalenol and nivalenol in wheat and barley in Japan. 1995 Sep-Oct Food Addit Contam pmid:8522034
Trucksess MW et al. Survey of deoxynivalenol in U.S. 1993 wheat and barley crops by enzyme-linked immunosorbent assay. 1995 May-Jun J AOAC Int pmid:7756875
Parent-Massin D and Thouvenot D In vitro toxicity of trichothecenes on rat haematopoietic progenitors. 1995 Jan-Feb Food Addit Contam pmid:7758630
Lambert LA et al. Lack of initiation and promotion potential of deoxynivalenol for skin tumorigenesis in Sencar mice. 1995 Food Chem. Toxicol. pmid:7896232
Azcona-Olivera JI et al. Effects of vomitoxin (deoxynivalenol) and cycloheximide on IL-2, 4, 5 and 6 secretion and mRNA levels in murine CD4+ cells. 1995 Food Chem. Toxicol. pmid:7797171
Greene DM et al. Effects of dihydrotestosterone and estradiol on experimental IgA nephropathy induced by vomitoxin. 1995 Fundam Appl Toxicol pmid:7657054
Kidd MT et al. Trichothecene mycotoxins depress the mononuclear-phagocytic system of young turkeys. 1995 Immunopharmacol Immunotoxicol pmid:7650297
Cossette F and Miller JD Phytotoxic effect of deoxynivalenol and gibberella ear rot resistance of corn. 1995 Nat. Toxins pmid:8581324
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Ouyang YL et al. Effects of trichothecene structure on cytokine secretion and gene expression in murine CD4+ T-cells. 1995 Toxicology pmid:8560498
Tani N et al. Antiviral activity of trichothecene mycotoxins (deoxynivalenol, fusarenon-X, and nivalenol) against herpes simplex virus types 1 and 2. 1995 Microbiol. Immunol. pmid:7494505
Gilbert J Analysis of mycotoxins in food and feed: certification of DON in wheat and maize. 1995 Nat. Toxins pmid:7582627
Azcona-Olivera JI et al. Induction of cytokine mRNAs in mice after oral exposure to the trichothecene vomitoxin (deoxynivalenol): relationship to toxin distribution and protein synthesis inhibition. 1995 Toxicol. Appl. Pharmacol. pmid:7597700
Böswald C et al. Metabolism of the Fusarium mycotoxins zearalenone and deoxynivalenol by yeast strains of technological relevance. 1995 Nat. Toxins pmid:7648022
Ruprich J and Ostry V Determination of the mycotoxin deoxynivalenol in beer by commercial elisa tests and estimation of the exposure dose from beer for the population in the Czech Republic. 1995 Cent. Eur. J. Public Health pmid:8903526
Fernandez C et al. Determination of deoxynivalenol in 1991 U.S. winter and spring wheat by high-performance thin-layer chromatography. 1994 May-Jun J AOAC Int pmid:8012211
Parent-Massin D et al. In vitro toxicity of trichothecenes on human haematopoietic progenitors. 1994 Jul-Aug Food Addit Contam pmid:7958114
Bergsjø B and Kaldhusdal M No association found between the ascites syndrome in broilers and feeding of oats contaminated with deoxynivalenol up to thirty-five days of age. 1994 Poult. Sci. pmid:7862615
Pestka JJ et al. Flow cytometric analysis of the effects of in vitro exposure to vomitoxin (deoxynivalenol) on apoptosis in murine T, B and IgA+ cells. 1994 Food Chem. Toxicol. pmid:7813984
Greene DM et al. Vomitoxin (deoxynivalenol)-induced IgA nephropathy in the B6C3F1 mouse: dose response and male predilection. 1994 Toxicology pmid:7940564
Rotter BA et al. Optimization of the mouse bioassay for deoxynivalenol as an alternative to large animal studies. 1994 Bull Environ Contam Toxicol pmid:7833598
Warner RL et al. In vitro effects of vomitoxin (deoxynivalenol) on T-cell interleukin production and IgA secretion. 1994 Food Chem. Toxicol. pmid:7913905
Rizzo AF et al. Protective effect of antioxidants against free radical-mediated lipid peroxidation induced by DON or T-2 toxin. 1994 Zentralbl Veterinarmed A pmid:8091893
Zakharova LP et al. [Grain contamination by deoxynivalenol in Russia]. 1994 Vopr Pitan pmid:7975431
Greene DM et al. Role of gender and strain in vomitoxin-induced dysregulation of IgA production and IgA nephropathy in the mouse. 1994 J Toxicol Environ Health pmid:8078091
Lu G et al. [Studies on deoxynivalenol contamination in grain and its products in Anhui Province]. 1994 Zhonghua Yu Fang Yi Xue Za Zhi pmid:8082456
Ossenkopp KP et al. Deoxynivalenol (vomitoxin)-induced conditioned taste aversions in rats are mediated by the chemosensitive area postrema. 1994 Pharmacol. Biochem. Behav. pmid:8146230
Mirocha CJ et al. Production of trichothecene mycotoxins by Fusarium graminearum and Fusarium culmorum on barley and wheat. 1994 Mycopathologia pmid:7708088
Dong W et al. Elevated gene expression and production of interleukins 2, 4, 5, and 6 during exposure to vomitoxin (deoxynivalenol) and cycloheximide in the EL-4 thymoma. 1994 Toxicol. Appl. Pharmacol. pmid:8048072
Pestka JJ and Dong W Progressive serum IgE elevation in the B6C3F1 mouse following withdrawal of dietary vomitoxin (deoxynivalenol). 1994 Fundam Appl Toxicol pmid:8005381
Prelusky DB The effect of deoxynivalenol on serotoninergic neurotransmitter levels in pig blood. 1994 J Environ Sci Health B pmid:7527434
Rotter BA et al. Influence of low-level exposure to Fusarium mycotoxins on selected immunological and hematological parameters in young swine. 1994 Fundam Appl Toxicol pmid:7958555
Yuwai KE et al. Occurrence of nivalenol, deoxynivalenol, and zearalenone in imported cereals in Papua, New Guinea. 1994 Nat. Toxins pmid:8032690
Prelusky DB et al. Effects of low-level dietary deoxynivalenol on haematological and clinical parameters of the pig. 1994 Nat. Toxins pmid:8087437
Rasooly L et al. Polyspecific and autoreactive IgA secreted by hybridomas derived from Peyer's patches of vomitoxin-fed mice: characterization and possible pathogenic role in IgA nephropathy. 1994 Food Chem. Toxicol. pmid:8206429
Kollarczik B et al. In vitro transformation of the Fusarium mycotoxins deoxynivalenol and zearalenone by the normal gut microflora of pigs. 1994 Nat. Toxins pmid:8087428