Vomitoxin

Vomitoxin is a lipid of Prenol Lipids (PR) class. Vomitoxin is associated with abnormalities such as Infection and Gastroenteritis. The involved functions are known as mRNA Expression, Inflammation, Transcription, Genetic, Protein Biosynthesis and Adverse effects. Vomitoxin often locates in Lymphoid Tissue, Immune system, Bone Marrow and Plasma membrane. The associated genes with Vomitoxin are IMPACT gene, HIST1H1C gene and RBM39 gene. The related experimental models are Mouse Model.

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Introduction

To understand associated biological information of Vomitoxin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Vomitoxin?

Vomitoxin is suspected in Infection, Gastroenteritis and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Vomitoxin

PubChem Associated disorders and diseases

What pathways are associated with Vomitoxin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Vomitoxin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Vomitoxin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Vomitoxin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Vomitoxin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Vomitoxin?

Mouse Model

Mouse Model are used in the study 'Dietary fish oil suppresses experimental immunoglobulin a nephropathy in mice.' (Pestka JJ et al., 2002).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Vomitoxin

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Authors Title Published Journal PubMed Link
Wong S et al. Superinduction of TNF-alpha and IL-6 in macrophages by vomitoxin (deoxynivalenol) modulated by mRNA stabilization. 2001 Toxicology pmid:11295263
Froquet R et al. Trichothecene toxicity on human megakaryocyte progenitors (CFU-MK). 2001 Hum Exp Toxicol pmid:11327514
Brown DW et al. A genetic and biochemical approach to study trichothecene diversity in Fusarium sporotrichioides and Fusarium graminearum. 2001 Fungal Genet. Biol. pmid:11352533
Fazekas B et al. Natural deoxynivalenol (DON) contamination of wheat samples grown in 1998 as determined by high-performance liquid chromatography. 2000 Acta Vet. Hung. pmid:11402697
Mateo JJ et al. Critical study of and improvements in chromatographic methods for the analysis of type B trichothecenes. 2001 J Chromatogr A pmid:11403460
Lee T et al. Identification of deoxynivalenol- and nivalenol-producing chemotypes of Gibberella zeae by using PCR. 2001 Appl. Environ. Microbiol. pmid:11425709
Meky FA et al. Deoxynivalenol-induced immunomodulation of human lymphocyte proliferation and cytokine production. 2001 Food Chem. Toxicol. pmid:11434990
Cazzaniga D et al. Mycotoxins inactivation by extrusion cooking of corn flour. 2001 Lett. Appl. Microbiol. pmid:11472523
Debouck C et al. Skeletal deformities induced by the intraperitoneal administration of deoxynivalenol (vomitoxin) in mice. 2001 Int Orthop pmid:11482540
Samar MM et al. Effect of fermentation on naturally occurring deoxynivalenol (DON) in Argentinean bread processing technology. 2001 Food Addit Contam pmid:11665728
Widestrand J and Pettersson H Effect of time, temperature and solvent on the stability of T-2 toxin, HT-2 toxin, deoxynivalenol and nivalenol calibrants. 2001 Food Addit Contam pmid:11665740
Langseth W et al. Production of culmorin compounds and other secondary metabolites by Fusarium culmorum and F. graminearum strains isolated from Norwegian cereals. 2001 Mycopathologia pmid:11694092
Froquet R et al. Improvement of megakaryocytic progenitor culture for toxicological investigations. 2001 Toxicol In Vitro pmid:11698171
Martins ML and Martins HM Determination of deoxynivalenol in wheat-based breakfast cereals marketed in Portugal. 2001 J. Food Prot. pmid:11726173
Krysińska-Traczyk E et al. Levels of fungi and mycotoxins in samples of grain and grain dust collected on farms in Eastern Poland. 2001 Ann Agric Environ Med pmid:11748887
Ghebremeskel M and Langseth W The occurrence of culmorin and hydroxy-culmorins in cereals. 2001 Mycopathologia pmid:11761144
Sugita-Konishi Y and Pestka JJ Differential upregulation of TNF-alpha, IL-6, and IL-8 production by deoxynivalenol (vomitoxin) and other 8-ketotrichothecenes in a human macrophage model. 2001 J. Toxicol. Environ. Health Part A pmid:11766169
Etzel RA Mycotoxins. 2002 Jan 23-30 JAMA pmid:11798344
Pestka JJ et al. Dietary fish oil suppresses experimental immunoglobulin a nephropathy in mice. 2002 J. Nutr. pmid:11823588
Schollenberger M et al. Fusarium toxins in wheat flour collected in an area in southwest Germany. 2002 Int. J. Food Microbiol. pmid:11843417
Olsson J et al. Detection and quantification of ochratoxin A and deoxynivalenol in barley grains by GC-MS and electronic nose. 2002 Int. J. Food Microbiol. pmid:11845819
Yang GH and Pestka JJ Vomitoxin (deoxynivalenol)-mediated inhibition of nuclear protein binding to NRE-A, an IL-2 promoter negative regulatory element, in EL-4 cells. 2002 Toxicology pmid:11893416
Maragos CM and Plattner RD Rapid fluorescence polarization immunoassay for the mycotoxin deoxynivalenol in wheat. 2002 J. Agric. Food Chem. pmid:11902919
Lombaert GA Methods for the determination of deoxynivalenol and other trichothecenes in foods. 2002 Adv. Exp. Med. Biol. pmid:11922082
Trigo-Stockli DM Effect of processing on deoxynivalenol and other trichothecenes. 2002 Adv. Exp. Med. Biol. pmid:11922085
Schaafsma AW Economic changes imposed by mycotoxins in food grains: case study of deoxynivalenol in winter wheat. 2002 Adv. Exp. Med. Biol. pmid:11922094
Schisler DA et al. Biological control of Fusarium head blight of wheat and deoxynivalenol levels in grain via use of microbial antagonists. 2002 Adv. Exp. Med. Biol. pmid:11922099
Whitaker TB et al. Sampling wheat for deoxynivalenol. 2002 Adv. Exp. Med. Biol. pmid:11922100
Islam Z et al. Endotoxin potentiation of trichothecene-induced lymphocyte apoptosis is mediated by up-regulation of glucocorticoids. 2002 Toxicol. Appl. Pharmacol. pmid:11922776
Pieters MN et al. Risk assessment of deoxynivalenol in food: concentration limits, exposure and effects. 2002 Adv. Exp. Med. Biol. pmid:11924598
Wang H et al. [Effect of deoxynivalenol and aflatoxin G1 on apoptosis of human blood lymphocytes in vitro]. 1999 Wei Sheng Yan Jiu pmid:11938994
Maragos CM et al. Fluorescence polarization as a tool for the determination of deoxynivalenol in wheat. 2002 Food Addit Contam pmid:11962698
Lee T et al. Tri13 and Tri7 determine deoxynivalenol- and nivalenol-producing chemotypes of Gibberella zeae. 2002 Appl. Environ. Microbiol. pmid:11976083
Bai GH et al. Deoxynivalenol-nonproducing fusarium graminearum causes initial infection, but does not cause disease spread in wheat spikes. 2002 Mycopathologia pmid:12000132
Berek L et al. The immunosuppressive effect of Fusarium mycotoxin as a function of HLA antigens. 2002 Acta Microbiol Immunol Hung pmid:12073830
Schnerr H et al. Correlation between DNA of trichothecene-producing Fusarium species and deoxynivalenol concentrations in wheat-samples. 2002 Lett. Appl. Microbiol. pmid:12100586
Swamy HV et al. Effects of feeding blends of grains naturally contaminated with Fusarium mycotoxins on production and metabolism in broilers. 2002 Poult. Sci. pmid:12162357
Wong SS et al. Effects of vomitoxin (deoxynivalenol) on the binding of transcription factors AP-1, NF-kappaB, and NF-IL6 in raw 264.7 macrophage cells. 2002 J. Toxicol. Environ. Health Part A pmid:12167214
Pestka JJ and Zhou HR Effects of tumor necrosis factor type 1 and 2 receptor deficiencies on anorexia, growth and IgA dysregulation in mice exposed to the trichothecene vomitoxin. 2002 Food Chem. Toxicol. pmid:12176089
Maresca M et al. The mycotoxin deoxynivalenol affects nutrient absorption in human intestinal epithelial cells. 2002 J. Nutr. pmid:12221236
Rodrigues-Fo E et al. Electron ionization mass spectral fragmentation of deoxynivalenol and related tricothecenes. 2002 Rapid Commun. Mass Spectrom. pmid:12271447
Szkudelska K et al. Short-time deoxynivalenol treatment induces metabolic disturbances in the rat. 2002 Toxicol. Lett. pmid:12368054
Moon Y and Pestka JJ Vomitoxin-induced cyclooxygenase-2 gene expression in macrophages mediated by activation of ERK and p38 but not JNK mitogen-activated protein kinases. 2002 Toxicol. Sci. pmid:12377986
Bakan B et al. Identification by PCR of Fusarium culmorum strains producing large and small amounts of deoxynivalenol. 2002 Appl. Environ. Microbiol. pmid:12406740
Alm H et al. The influence of the mycotoxins deoxynivalenol and zearalenol on in vitro maturation of pig oocytes and in vitro culture of pig zygotes. 2002 Toxicol In Vitro pmid:12423645
Dänicke S et al. Effect of addition of a detoxifying agent to laying hen diets containing uncontaminated or Fusarium toxin-contaminated maize on performance of hens and on carryover of zearalenone. 2002 Poult. Sci. pmid:12455595
Leblanc JC et al. Simulation of the exposure to deoxynivalenol of French consumers of organic and conventional foodstuffs. 2002 Regul. Toxicol. Pharmacol. pmid:12460749
Eriksen GS et al. Transformation of trichothecenes in ileal digesta and faeces from pigs. 2002 Arch Tierernahr pmid:12462911
Rupp HS Determination of deoxynivalenol in whole wheat flour and wheat bran. 2002 Nov-Dec J AOAC Int pmid:12477199
Meky FA et al. Development of a urinary biomarker of human exposure to deoxynivalenol. 2003 Food Chem. Toxicol. pmid:12480302