Alpha-santonin is a lipid of Prenol Lipids (PR) class.
We collected disease MeSH terms mapped to the references associated with alpha-Santonin
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Edema | D004487 | 152 associated lipids |
| Brain Diseases | D001927 | 27 associated lipids |
| Leukemia | D007938 | 74 associated lipids |
| Toxocariasis | D014120 | 3 associated lipids |
| Sunstroke | D013474 | 1 associated lipids |
| Enterobiasis | D017229 | 1 associated lipids |
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Sakipova Z et al. | Quantification of santonin in eight species of Artemisia from Kazakhstan by means of HPLC-UV: Method development and validation. | 2017 | PLoS ONE | pmid:28301522 |
| Ratajewski M et al. | Screening of a chemical library reveals novel PXR-activating pharmacologic compounds. | 2015 | Toxicol. Lett. | pmid:25455453 |
| Khazir J et al. | Synthesis and anticancer activity of novel spiro-isoxazoline and spiro-isoxazolidine derivatives of α-santonin. | 2013 | Eur J Med Chem | pmid:23501113 |
| Born S et al. | The human bitter taste receptor TAS2R10 is tailored to accommodate numerous diverse ligands. | 2013 | J. Neurosci. | pmid:23283334 |
| Ferreira JR et al. | Induction of G₂/M arrest, caspase activation and apoptosis by α-santonin derivatives in HL-60 cells. | 2013 | Toxicol In Vitro | pmid:23542210 |
| Kittayaruksakul S et al. | Identification of three novel natural product compounds that activate PXR and CAR and inhibit inflammation. | 2013 | Pharm. Res. | pmid:23896737 |
| Chinthakindi PK et al. | Diminutive effect on T and B-cell proliferation of non-cytotoxic α-santonin derived 1,2,3-triazoles: a report. | 2013 | Eur J Med Chem | pmid:23314050 |
| Dutto M et al. | [Enterobiasis in pediatric subjects in north-western Italy: a study of home remedies]. | 2012 Jan-Feb | Ann Ig | pmid:22670340 |
| Yousuf S et al. | 8-[(2-Hy-droxy-phen-yl)imino]-3,5a,9-trimethyl-3a,4,5,5a,8,9b-hexa-hydro-naphtho-[1,2-b]furan-2(3H)-one. | 2012 | Acta Crystallogr Sect E Struct Rep Online | pmid:22798830 |
| Yousuf S et al. | 3,5a,9-Trimethyl-8-(2-phenylhydrazin-1-ylidene)-4,5,5a,9b-tetrahydro-3aH,8H-naphtho[1,2-b]furan-2(3H)-one. | 2012 | Acta Crystallogr Sect E Struct Rep Online | pmid:22798789 |
| Chen X et al. | Theoretical studies on the photoinduced rearrangement mechanism of α-santonin. | 2012 | Chemphyschem | pmid:22120926 |
| Tamura R et al. | Santonin-related compound 2 inhibits the nuclear translocation of NF-κB subunit p65 by targeting cysteine 38 in TNF-α-induced NF-κB signaling pathway. | 2012 | Biosci. Biotechnol. Biochem. | pmid:23221713 |
| Becker JV et al. | In vitro anti-plasmodial activity of Dicoma anomala subsp. gerrardii (Asteraceae): identification of its main active constituent, structure-activity relationship studies and gene expression profiling. | 2011 | Malar. J. | pmid:21985233 |
| Chen X et al. | Role of the 3(ππ*) state in photolysis of lumisantonin: insight from ab initio studies. | 2011 | J Phys Chem A | pmid:21627307 |
| Yamaura T | [History of the Nippon Shinyaku Institute for Botanical Research]. | 2011 | Yakugaku Zasshi | pmid:21372535 |
| Kweon SH et al. | Synthesis of C (6)-epimer derivatives of diacetoxy acetal derivative of santonin and their inducing effects on HL-60 leukemia cell differentiation. | 2011 | Arch. Pharm. Res. | pmid:21380800 |
| Arantes FF et al. | Synthesis of novel α-santonin derivatives as potential cytotoxic agents. | 2010 | Eur J Med Chem | pmid:20971532 |
| Tanrikulu Y et al. | Structure-based pharmacophore screening for natural-product-derived PPARgamma agonists. | 2009 | Chembiochem | pmid:19067454 |
| Arantes FF et al. | Synthesis and cytotoxic activity of alpha-santonin derivatives. | 2009 | Eur J Med Chem | pmid:19406535 |
| Casey RJ et al. | Expanding the repertoire of small molecule transcriptional activation domains. | 2009 | Bioorg. Med. Chem. | pmid:18334300 |
| Pagán OR et al. | Reversal of cocaine-induced planarian behavior by parthenolide and related sesquiterpene lactones. | 2008 | Pharmacol. Biochem. Behav. | pmid:18222535 |
| Kim SH et al. | Synthesis of DAAS derivatives and their enhancement of HL-60 leukemia cell differentiation. | 2008 | Arch. Pharm. Res. | pmid:18409041 |
| Yang L and Dai J | Biotransformation of tetrahydro-alpha-santonins by Absidia coerulea. | 2008 | Nat. Prod. Res. | pmid:18415857 |
| Schwarz O et al. | Natural products in parallel chemistry--novel 5-lipoxygenase inhibitors from BIOS-based libraries starting from alpha-santonin. | 2007 Nov-Dec | J Comb Chem | pmid:17850107 |
| Raj MS et al. | Periplasmically located α-santonin binding factor in Sphingomonas paucimobilis strain S ATCC 43388. | 2007 | Indian J. Microbiol. | pmid:23100690 |
| Harper JK et al. | Pursuing structure in microcrystalline solids with independent molecules in the unit cell using 1H-13C correlation data. | 2007 | J. Magn. Reson. | pmid:17869558 |
| Yang L et al. | Biotransformation of alpha- and 6beta-santonin by fungus and plant cell cultures. | 2006 | J Asian Nat Prod Res | pmid:16864442 |
| Kim SH et al. | Synthesis of diacetoxy acetal derivatives of santonin and their enhancing effects on HL-60 leukemia cell differentiation. | 2006 | Arch. Pharm. Res. | pmid:16491841 |
| Kim SH et al. | Chemical modification of santonin into a diacetoxy acetal form confers the ability to induce differentiation of human promyelocytic leukemia cells via the down-regulation of NF-kappaB DNA binding activity. | 2006 | J. Biol. Chem. | pmid:16554308 |
| Sukul NC et al. | Amelioration of root-knot disease of lady's finger plants by potentized Cina and Santonin. | 2006 | Homeopathy | pmid:16815517 |
| Yang L and Dai JG | Biotransformation of 6beta-santonin by Phytolacca acinosa cell suspension cultures. | 2005 | Yao Xue Xue Bao | pmid:16342687 |
| Yang L et al. | Biotransformation of alpha-santonin by cell suspension cultures of five plants. | 2005 | Biotechnol. Lett. | pmid:16086262 |
| Ata A and Nachtigall JA | Microbial transformations of alpha-santonin. | 2004 Mar-Apr | Z. Naturforsch., C, J. Biosci. | pmid:15241928 |
| Blay G et al. | Synthesis of Spirovetivane Sesquiterpenes from Santonin. Synthesis of (+)-Anhydro-beta-rotunol and all diastereomers of 6,11-spirovetivadiene. | 2004 | J. Org. Chem. | pmid:15471483 |
| Prangé T et al. | Synthesis of phytuberin. 4-endo-tet acid-catalyzed cyclization of alpha-hydroxy epoxides. | 2003 | J. Org. Chem. | pmid:12762747 |
| Birladeanu L | The stories of santonin and santonic acid. | 2003 | Angew. Chem. Int. Ed. Engl. | pmid:12645053 |
| Bargues V et al. | Stereoselective synthesis of (+)-11betaH,13-dihydroestafiatin, (+)-11betaH,13-dihydroludartin, (-)-compressanolide, and (-)-11betaH,13-dihydromicheliolide from santonin. | 2002 | J. Nat. Prod. | pmid:12444708 |
| Kang SN et al. | Enhancement of 1 alpha,25-dihydroxyvitamin D(3)-induced differentiation of human leukaemia HL-60 cells into monocytes by parthenolide via inhibition of NF-kappa B activity. | 2002 | Br. J. Pharmacol. | pmid:11877332 |
| Cantrell CL et al. | Antimycobacterial plant terpenoids. | 2001 | Planta Med. | pmid:11731906 |
| Blay G et al. | Synthesis of plagiochiline N from santonin. | 2001 | J. Org. Chem. | pmid:11701024 |
| Singh B et al. | Individual and combined effects of berberine and santonin on spore germination of some fungi. | 2001 | Folia Microbiol. (Praha) | pmid:11501401 |
| Farooq A and Tahara S | Biotransformation of two cytotoxic terpenes, alpha-santonin and sclareol by Botrytis cinerea. | 2000 Sep-Oct | Z. Naturforsch., C, J. Biosci. | pmid:11098821 |
| Blay G et al. | Stereoselective synthesis of 7,11-guaien-8,12-olides from santonin. Synthesis of podoandin and (+)-zedolactone A. | 2000 | J. Org. Chem. | pmid:11052122 |
| Kawai S et al. | Santonin-related compound 2 inhibits the expression of ICAM-1 in response to IL-1 stimulation by blocking the signaling pathway upstream of I kappa B degradation. | 2000 | Immunopharmacology | pmid:10936510 |
| Kawamata T et al. | [Reaction of 3-hydroxy-dihydrosantonin with TsOH. A formal synthesis of dihydrocotunolide]. | 1996 | Yakugaku Zasshi | pmid:8855720 |
| al-Harbi MM et al. | Studies on the antiinflammatory, antipyretic and analgesic activities of santonin. | 1994 | Jpn. J. Pharmacol. | pmid:8022114 |
| Perez-Souto N et al. | Use of high-performance liquid chromatographic peak deconvolution and peak labelling to identify antiparasitic components in plant extracts. | 1992 | J. Chromatogr. | pmid:1639905 |
| Bharathi A and Polasa H | Elimination of broad-host range plasmid vectors in Escherichia coli by curing agents. | 1991 | FEMS Microbiol. Lett. | pmid:1769553 |
| Arnold WN and Loftus LS | Xanthopsia and van Gogh's yellow palette. | 1991 | Eye (Lond) | pmid:1794418 |
| Bharathi A and Polasa H | Elimination of ColE1 group (pBR322 and pBR329) plasmids in Escherichia coli by alpha-santonin. | 1990 | FEMS Microbiol. Lett. | pmid:2185125 |
| Roberts JA | Toxocara vitulorum: treatment based on the duration of the infectivity of buffalo cows (Bubalus bubalis) for their calves. | 1989 | J. Vet. Pharmacol. Ther. | pmid:2704061 |
| MartÃn ML et al. | Antipyretic activity of alpha- and beta-santonin. | 1988 Jul-Aug | J Ethnopharmacol | pmid:3193791 |
| Vennerstrom JL and Eaton JW | Oxidants, oxidant drugs, and malaria. | 1988 | J. Med. Chem. | pmid:3290484 |
| Naik U and Mavuinkurve S | alpha-Santonin 1,2-reductase and its role in the formation of dihydrosantonin and lumisantonin by Pseudomonas cichorii S. | 1987 | Can. J. Microbiol. | pmid:3690421 |
| Rossi C et al. | Synthesis and in vitro cytotoxic activity of semisynthetic derivatives in the santonin series. | 1986 | J Pharm Sci | pmid:3772751 |
| Azoulay P et al. | [Helenine and santonine, the 12-carboxy-eudesma-3,11(13) diene]. | 1986 | Pharm Acta Helv | pmid:3809210 |
| Habib AA et al. | Difference spectrophotometric estimation of santonin. | 1984 Sep-Oct | J Assoc Off Anal Chem | pmid:6501159 |
| Perdriel G and Manent PJ | [Drug-induced dyschromatopsias]. | 1982 | Annee Ther Clin Ophtalmol | pmid:6764596 |
| Akhtar MS et al. | Comparative efficacy of santonin and piperazine against Neoascaris vitulorum in buffalo calves. | 1982 | J. Vet. Pharmacol. Ther. | pmid:7097849 |
| Liu XL | [Separation and assay of santonin isomers by HPLC]. | 1982 | Yao Xue Xue Bao | pmid:7158356 |
| Iida M et al. | Studies on microbial transformations. XVIII. Microbiological transformation of 1-alpha-santonin. | 1981 | Z. Allg. Mikrobiol. | pmid:6800142 |
| Luo SR and He LY | [TLC separation and densitometry of alpha-and beta-santonin in Artemisia (author's transl)]. | 1980 | Yao Xue Xue Bao | pmid:7257792 |
| Fujimoto Y et al. | [Studies on the microbiological transformation of alpha-santonin and its analogues (author's transl)]. | 1978 | Yakugaku Zasshi | pmid:650400 |
| Balynina ES | [Study of the detoxifying oxidative function of the liver by the santonin test]. | 1976 | Gig Tr Prof Zabol | pmid:1261867 |
| Sheth UK | Mechanisms of anthelmintic action. | 1975 | Prog Drug Res | pmid:769059 |
| Tsanov TsS | [Study of the therapeutic effect of santamon in ascaridiasis in swine]. | 1973 | Vet Med Nauki | pmid:4802756 |
| Gibson TE | The value of pharmacological studies in the development of new antinematodal drugs. | 1971 | J. Parasitol. | pmid:4942859 |
| Oldham RR et al. | Hemolytic crisis in a patient treated with santonin: possible santonin poisoning. | 1971 | South. Med. J. | pmid:5552023 |
| Khafagy SM et al. | Phytochemical investigation of Artemisia herba alba. | 1971 | Planta Med. | pmid:5154610 |
| Tverskaya MIa and Ivanova TP | [Modification of the method of determining the antitoxic function of the liver (according to the santonin loading test)]. | 1971 | Gig Sanit | pmid:5148709 |
| Demina AI | [Isolation of sesquiterpene lactone from wormwood of the Northwestern shores of the Black Sea and its identification]. | 1970 May-Jun | Farmatsiia | pmid:5429702 |
| Marsh G et al. | Investigation of singlet--triplet and singlet--singlet transitions by phosphorescence excitation spectroscopy. 8. Santonins. | 1970 | J. Am. Chem. Soc. | pmid:5438016 |
| White EH and Wei CC | A possible role for chemically-produced excited states in biology. | 1970 | Biochem. Biophys. Res. Commun. | pmid:5513255 |
| Perold GW and Ourisson G | [Photolysis of dihydro-1,2-(6 beta, ll alpha and ll beta)-santonins. A stereospecific intramolecular photosensitization]. | 1969 | Tetrahedron Lett. | pmid:5348313 |
| Boyland E and Chasseaud LF | Enzyme-catalysed conjugations of glutathione with unsaturated compounds. | 1967 | Biochem. J. | pmid:6035529 |
| DZHALILOV DR et al. | [POLAROGRAPHIC DETERMINATION OF SANTONIN IN ARTEMISIA CINA]. | 1965 Jan-Feb | Aptechn Delo | pmid:14345298 |
| Asher JD and Sim GA | Sesquiterpenoids. 3. The stereochemistry of santonin: x-ray analysis of 2-bromo-alpha-santonin. | 1965 | J. Chem. Soc. Perkin Trans. I | pmid:5891961 |
| Corey EJ and Hortmann AG | The total synthesis of dihydrocostunolide. | 1965 | J. Am. Chem. Soc. | pmid:5845424 |
| GENTILINI M and THERIZOL M | [ASCARIDIOSIS. SYMPTOMS, DIAGNOSIS AND TREATMENT]. | 1964 | Concours Med | pmid:14200295 |
| MATSUSAKI G et al. | STUDIES ON ANTHELMINTICS FOR ASCARIS LUMBRICOIDES. | 1964 | Yokohama Med Bull | pmid:14279448 |
| SALUNKHE DS et al. | CLINICAL EVALUATION OF A NEW ANTHELMINTICTHIABENDAZOLE (2-(4'-THIAZOLYL)-BENZIMIDAZOLE). | 1964 | Am. J. Trop. Med. Hyg. | pmid:14159978 |
| WACHSMUTH H and VAN KOECKHOVEN L | [Fluorometric determination of santonin]. | 1963 May-Jun | J Pharm Belg | pmid:13998116 |
| KAWATANI T and ONO T | [ON A TRIAL CULTIVATION OF ARTEMISIA MARITIMA L. VAR. SALINA KOCH OF BULGARIAN ORIGIN]. | 1963 | Eisei Shikenjo Hokoku | pmid:14162008 |
| RYBALKO KS et al. | [ON SESQUITERPENE LACTONES FROM SOME SPECIES OF ARTEMISIA]. | 1963 | Med Prom SSSR | pmid:14076644 |
| POULET J | [THE TREATMENT OF PULMONARY PARASITOSES]. | 1963 | Cah Coll Med Hop Paris | pmid:14092494 |
| BANDO T | [MECHANISM OF ACTION OF ANTHELMINTICS]. | 1963 | Sogo Rinsho | pmid:14092557 |
| SATODA I and YOSHII E | [The structure of photosantoninic acid. III]. | 1963 | Yakugaku Zasshi | pmid:13986752 |
| SATODA I and YOSHII E | [The structure of photosantoninic acid. I]. | 1963 | Yakugaku Zasshi | pmid:13986753 |
| KUCHERENKO EM and KADOSHCHUK TA | [Clinical significance of liver function tests with santonin]. | 1962 | Ter. Arkh. | pmid:13927281 |
| SERITA K | [Studies on the relation of santonin and choleretics in anthelmintic effectiveness. III. Investigation of molecular compounds made up of 2 components, santonin and a cholertic, with special reference to the pharmacological action to the benzoic acid-santonin molecular compound]. | 1962 | Nippon Yakurigaku Zasshi | pmid:13910832 |
| KURODA T | [Studies on the chemical and botanical properties of Artemisia kurramensis Qazilbash cultivated in Japan. II. Components of santonin]. | 1962 | Yakugaku Zasshi | pmid:14460771 |
| KURODA T | [Studies on the chemical and botanical properties of Artemisia kurramensis Qazilbash cultivated in Japan. I. Improvement of gravimetric analysis of santonin in crude drugs and santonin content of Artemisia kurramensis]. | 1962 | Yakugaku Zasshi | pmid:14460774 |
| YAMASAKI H et al. | Pharmacological studies of lumisantonin derivatives, with special reference to anti-inflammatory effect and to histamine-release inhibitory action. | 1961 | Acta Med Okayama | pmid:14008895 |
| FUJISHIRO Y | [Hydroxysantonin in the rabbit and man and the effect of dehydrocholic acid on it]. | 1961 | Nippon Yakurigaku Zasshi | pmid:13702478 |
| MORISHIMA E | [The fate of santonin in the rabbit and in man, and the effect upon it of dehydrocholic acid]. | 1961 | Nippon Yakurigaku Zasshi | pmid:13772681 |
| MISRA N et al. | Oral contraceptives. VI. Hormonal and antihormonal effects of santonin. | 1961 | Indian J. Physiol. Pharmacol. | pmid:14474564 |
| CAVIER R and NOTTEGHEM MJ | [Contribution to the study of the anthelmintic properties of kainic acid. I. The combination of santonin and kainic acid]. | 1960 | Therapie | pmid:13691770 |
| KHAN RA and MOHIUDDIN H | The colorimetric determination of santonin in Artemisia. | 1960 | J. Pharm. Pharmacol. | pmid:13755611 |
| GOODWIN LG | A method for recording the effects of anthelmintics on the movements of Ascaris lumbricoides. | 1958 | Br J Pharmacol Chemother | pmid:13536286 |
| KASSNER EW et al. | A note on the assay of Artemisia. | 1953 | J. Pharm. Pharmacol. | pmid:13053433 |