| MeSH term | MeSH ID | Detail |
|---|---|---|
| Dermatitis, Contact | D003877 | 59 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
Total
2
Alantolactone
Alantolactone is a lipid of Prenol Lipids (PR) class.
Cross Reference
There are no associated biomedical information in the current reference collection.
Current reference collection contains 323 references associated with Alantolactone in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.
Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.
Here are additional resources we collected from PubChem and MeSH for Alantolactone
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Alantolactone
NCBI Entrez Crosslinks
All references with Alantolactone
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Ding Y et al. | Induction of ROS Overload by Alantolactone Prompts Oxidative DNA Damage and Apoptosis in Colorectal Cancer Cells. | 2016 | Int J Mol Sci | pmid:27089328 |
| Rezeng C et al. | Alantolactone exhibited anti-herpes simplex virus 1 (HSV-1) action in vitro. | 2015 | Biosci Trends | pmid:26781801 |
| Xu R et al. | Pharmacokinetics, tissue distribution and excretion of isoalantolactone and alantolactone in rats after oral administration of Radix Inulae extract. | 2015 | Molecules | pmid:25927901 |
| Mi XG et al. | Alantolactone induces cell apoptosis partially through down-regulation of testes-specific protease 50 expression. | 2014 | Toxicol. Lett. | pmid:24252419 |
| Alzoubi K et al. | Triggering of programmed erythrocyte death by alantolactone. | 2014 | Toxins (Basel) | pmid:25533522 |
| Wei W et al. | Alantolactone induces apoptosis in chronic myelogenous leukemia sensitive or resistant to imatinib through NF-κB inhibition and Bcr/Abl protein deletion. | 2013 | Apoptosis | pmid:23613107 |
| Khan M et al. | Alantolactone induces apoptosis in HepG2 cells through GSH depletion, inhibition of STAT3 activation, and mitochondrial dysfunction. | 2013 | Biomed Res Int | pmid:23533997 |
| Yang C et al. | Alantolactone inhibits growth of K562/adriamycin cells by downregulating Bcr/Abl and P-glycoprotein expression. | 2013 | IUBMB Life | pmid:23441067 |
| Zhang Y et al. | Alantolactone induces apoptosis in RKO cells through the generation of reactive oxygen species and the mitochondrial pathway. | 2013 | Mol Med Rep | pmid:23970102 |
| Rasul A et al. | Targeting apoptosis pathways in cancer with alantolactone and isoalantolactone. | 2013 | ScientificWorldJournal | pmid:24288468 |
| Ma YY et al. | Structural investigation and biological activity of sesquiterpene lactones from the traditional Chinese herb Inula racemosa. | 2013 | J. Nat. Prod. | pmid:23451797 |
| Ariyoshi W et al. | Mechanisms involved in enhancement of the expression and function of aggrecanases by hyaluronan oligosaccharides. | 2012 | Arthritis Rheum. | pmid:21905012 |
| Chun J et al. | Alantolactone suppresses inducible nitric oxide synthase and cyclooxygenase-2 expression by down-regulating NF-κB, MAPK and AP-1 via the MyD88 signaling pathway in LPS-activated RAW 264.7 cells. | 2012 | Int. Immunopharmacol. | pmid:22940184 |
| Lei JC et al. | Alantolactone induces activation of apoptosis in human hepatoma cells. | 2012 | Food Chem. Toxicol. | pmid:22721982 |
| Khan M et al. | Alantolactone induces apoptosis in glioblastoma cells via GSH depletion, ROS generation, and mitochondrial dysfunction. | 2012 | IUBMB Life | pmid:22837216 |
| Coelius RL et al. | The tibetan uterotonic zhi byed 11: mechanisms of action, efficacy, and historical use for postpartum hemorrhage. | 2012 | Evid Based Complement Alternat Med | pmid:21822444 |
| Wang J et al. | Ultrasound-assisted extraction of total flavonoids from Inula helenium. | 2012 | Pharmacogn Mag | pmid:22701292 |
| Gupta A et al. | Evaluation of protective effect of Butea monosperma (lam.) Taub in experimental hepatotoxicity in rats. | 2012 | J Pharmacol Pharmacother | pmid:22629095 |
| Khan M et al. | Isoalantolactone induces reactive oxygen species mediated apoptosis in pancreatic carcinoma PANC-1 cells. | 2012 | Int. J. Biol. Sci. | pmid:22532787 |
| Cheng X et al. | Sesquiterpene lactones from Inula falconeri, a plant endemic to the Himalayas, as potential anti-inflammatory agents. | 2011 | Eur J Med Chem | pmid:21924800 |
| Galvez-Llompart M et al. | Modeling natural anti-inflammatory compounds by molecular topology. | 2011 | Int J Mol Sci | pmid:22272145 |
| van Haaften C et al. | Potent cytotoxic effects of Calomeria amaranthoides on ovarian cancers. | 2011 | J. Exp. Clin. Cancer Res. | pmid:21401934 |
| Paulsen E and Andersen KE | Screening for Compositae sensitization with pure allergens: implications of molecular structure, strength of reaction, and time of testing. | 2011 | Contact Derm. | pmid:21138444 |
| Shi Y et al. | Alantolactone inhibits cell proliferation by interrupting the interaction between Cripto-1 and activin receptor type II A in activin signaling pathway. | 2011 | J Biomol Screen | pmid:21378277 |
| Seo JY et al. | Protection by Chrysanthemum zawadskii extract from liver damage of mice caused by carbon tetrachloride is maybe mediated by modulation of QR activity. | 2010 | Nutr Res Pract | pmid:20461196 |
| Bairwa NK et al. | Protective effect of stem bark of Ceiba pentandra linn. against paracetamol-induced hepatotoxicity in rats. | 2010 | Pharmacognosy Res | pmid:21808535 |
| Trendafilova A et al. | Ultrasound-assisted extraction of alantolactone and isoalantolactone from Inula helenium roots. | 2010 | Pharmacogn Mag | pmid:20931085 |
| Huo Y et al. | HPLC determination and NMR structural elucidation of sesquiterpene lactones in Inula helenium. | 2010 | J Pharm Biomed Anal | pmid:19889507 |
| Cantrell CL et al. | Structure-activity relationship studies on derivatives of eudesmanolides from Inula helenium as toxicants against Aedes aegypti larvae and adults. | 2010 | Chem. Biodivers. | pmid:20658657 |
| Xin XL et al. | Microbial transformation of alantolactone by Mucor polymorphosporus. | 2008 Sep-Oct | J Asian Nat Prod Res | pmid:19003611 |
| Tong L et al. | A rapid identification of Radix inulae and its active component alantolactone in the Tibetan medicine Manuxitang. | 2008 | Biosci Trends | pmid:20103903 |
| Seo JY et al. | Nrf2-mediated induction of detoxifying enzymes by alantolactone present in Inula helenium. | 2008 | Phytother Res | pmid:18702092 |
| Hwang DR et al. | Synthesis and anti-viral activity of a series of sesquiterpene lactones and analogues in the subgenomic HCV replicon system. | 2006 | Bioorg. Med. Chem. | pmid:16140536 |
| Meng JC et al. | Antifungal highly oxygenated guaianolides and other constituents from Ajania fruticulosa. | 2001 | Phytochemistry | pmid:11730880 |
| Cantrell CL et al. | Antimycobacterial plant terpenoids. | 2001 | Planta Med. | pmid:11731906 |
| Kanerva L et al. | Patch test sensitization to Compositae mix, sesquiterpene-lactone mix, Compositae extracts, laurel leaf, Chlorophorin, Mansonone A, and dimethoxydalbergione. | 2001 | Am. J. Contact Dermatitis | pmid:11244135 |
| Lawrence NJ et al. | Cytotoxic Michael-type amine adducts of alpha-methylene lactones alantolactone and isoalantolactone. | 2001 | Bioorg. Med. Chem. Lett. | pmid:11212128 |
| Kuno Y et al. | Allergic contact dermatitis associated with photosensitivity, from alantolactone in a chrysanthemum farmer. | 1999 | Contact Derm. | pmid:10208523 |
| Cantrell CL et al. | Antimycobacterial eudesmanolides from Inula helenium and Rudbeckia subtomentosa. | 1999 | Planta Med. | pmid:10364842 |
| Mateo MP et al. | Erythema-multiforme-like eruption following allergic contact dermatitis from sesquiterpene lactones in herbal medicine. | 1995 | Contact Derm. | pmid:8706423 |
| Quirce S et al. | Airborne contact dermatitis from Frullania. | 1994 | Contact Derm. | pmid:8187505 |
| Ross JS et al. | Sesquiterpene lactone contact sensitivity: clinical patterns of Compositae dermatitis and relationship to chronic actinic dermatitis. | 1993 | Contact Derm. | pmid:8365182 |
| Alonso Blasi N et al. | A murine in vitro model of allergic contact dermatitis to sesquiterpene alpha-methylene-gamma-butyrolactones. | 1992 | Arch. Dermatol. Res. | pmid:1444579 |
| Fraginals R et al. | A successful murine model for contact sensitization to a sesquiterpene-alpha-methylene-gamma-butyrolactone: sensitization to alantolactone in four strains of mice. | 1991 | J. Invest. Dermatol. | pmid:1875047 |
| Picman J and Picman AK | Treatment of dermatitis caused by the sesquiterpene lactone helenin. | 1990 | Pharmazie | pmid:2333316 |
| Chapman DE et al. | In vitro inhibition of mouse hepatic mixed-function oxidase enzymes by helenalin and alantolactone. | 1989 | Biochem. Pharmacol. | pmid:2512929 |
| Pinedo JM et al. | Contact dermatitis to sesquiterpene lactones in Inula viscosa Aiton. | 1987 | Contact Derm. | pmid:3325222 |
| Sertoli A et al. | [Contact eczema caused by Chrysanthemum morifolium Ramat]. | 1985 Sep-Oct | G Ital Dermatol Venereol | pmid:4077111 |
| Dalvi RR and McGowan C | Helenin inhibition of liver microsomal enzymes. | 1982 Sep-Oct | J. Agric. Food Chem. | pmid:7142596 |
| Stampf JL et al. | The sensitizing capacity of helenin and of two of its main constituents, the sesquiterpene lactones alantolactone and isoalantolactone: a comparison of epicutaneous and intradermal sensitizing methods in different strains of guinea pig. | 1982 | Contact Derm. | pmid:7067436 |
| Gabriel-Robez O et al. | Allergic contact dermatitis to methylenelactones. Use of lymphocyte transformation test. | 1982 | Arch. Dermatol. Res. | pmid:7165323 |
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