Alantolactone

Alantolactone is a lipid of Prenol Lipids (PR) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 323 references associated with Alantolactone in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for Alantolactone

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Alantolactone

MeSH term MeSH ID Detail
Dermatitis, Contact D003877 59 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Total 2

NCBI Entrez Crosslinks

All references with Alantolactone

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Kanerva L et al. Patch test sensitization to Compositae mix, sesquiterpene-lactone mix, Compositae extracts, laurel leaf, Chlorophorin, Mansonone A, and dimethoxydalbergione. 2001 Am. J. Contact Dermatitis pmid:11244135
Wei W et al. Alantolactone induces apoptosis in chronic myelogenous leukemia sensitive or resistant to imatinib through NF-κB inhibition and Bcr/Abl protein deletion. 2013 Apoptosis pmid:23613107
Alonso Blasi N et al. A murine in vitro model of allergic contact dermatitis to sesquiterpene alpha-methylene-gamma-butyrolactones. 1992 Arch. Dermatol. Res. pmid:1444579
Gabriel-Robez O et al. Allergic contact dermatitis to methylenelactones. Use of lymphocyte transformation test. 1982 Arch. Dermatol. Res. pmid:7165323
Ariyoshi W et al. Mechanisms involved in enhancement of the expression and function of aggrecanases by hyaluronan oligosaccharides. 2012 Arthritis Rheum. pmid:21905012
Chapman DE et al. In vitro inhibition of mouse hepatic mixed-function oxidase enzymes by helenalin and alantolactone. 1989 Biochem. Pharmacol. pmid:2512929
Khan M et al. Alantolactone induces apoptosis in HepG2 cells through GSH depletion, inhibition of STAT3 activation, and mitochondrial dysfunction. 2013 Biomed Res Int pmid:23533997
Hwang DR et al. Synthesis and anti-viral activity of a series of sesquiterpene lactones and analogues in the subgenomic HCV replicon system. 2006 Bioorg. Med. Chem. pmid:16140536
Lawrence NJ et al. Cytotoxic Michael-type amine adducts of alpha-methylene lactones alantolactone and isoalantolactone. 2001 Bioorg. Med. Chem. Lett. pmid:11212128
Tong L et al. A rapid identification of Radix inulae and its active component alantolactone in the Tibetan medicine Manuxitang. 2008 Biosci Trends pmid:20103903
Rezeng C et al. Alantolactone exhibited anti-herpes simplex virus 1 (HSV-1) action in vitro. 2015 Biosci Trends pmid:26781801
Cantrell CL et al. Structure-activity relationship studies on derivatives of eudesmanolides from Inula helenium as toxicants against Aedes aegypti larvae and adults. 2010 Chem. Biodivers. pmid:20658657
Paulsen E and Andersen KE Screening for Compositae sensitization with pure allergens: implications of molecular structure, strength of reaction, and time of testing. 2011 Contact Derm. pmid:21138444
Pinedo JM et al. Contact dermatitis to sesquiterpene lactones in Inula viscosa Aiton. 1987 Contact Derm. pmid:3325222
Mateo MP et al. Erythema-multiforme-like eruption following allergic contact dermatitis from sesquiterpene lactones in herbal medicine. 1995 Contact Derm. pmid:8706423
Stampf JL et al. The sensitizing capacity of helenin and of two of its main constituents, the sesquiterpene lactones alantolactone and isoalantolactone: a comparison of epicutaneous and intradermal sensitizing methods in different strains of guinea pig. 1982 Contact Derm. pmid:7067436
Quirce S et al. Airborne contact dermatitis from Frullania. 1994 Contact Derm. pmid:8187505
Ross JS et al. Sesquiterpene lactone contact sensitivity: clinical patterns of Compositae dermatitis and relationship to chronic actinic dermatitis. 1993 Contact Derm. pmid:8365182
Kuno Y et al. Allergic contact dermatitis associated with photosensitivity, from alantolactone in a chrysanthemum farmer. 1999 Contact Derm. pmid:10208523
Cheng X et al. Sesquiterpene lactones from Inula falconeri, a plant endemic to the Himalayas, as potential anti-inflammatory agents. 2011 Eur J Med Chem pmid:21924800
Coelius RL et al. The tibetan uterotonic zhi byed 11: mechanisms of action, efficacy, and historical use for postpartum hemorrhage. 2012 Evid Based Complement Alternat Med pmid:21822444
Lei JC et al. Alantolactone induces activation of apoptosis in human hepatoma cells. 2012 Food Chem. Toxicol. pmid:22721982
Sertoli A et al. [Contact eczema caused by Chrysanthemum morifolium Ramat]. 1985 Sep-Oct G Ital Dermatol Venereol pmid:4077111
Galvez-Llompart M et al. Modeling natural anti-inflammatory compounds by molecular topology. 2011 Int J Mol Sci pmid:22272145
Ding Y et al. Induction of ROS Overload by Alantolactone Prompts Oxidative DNA Damage and Apoptosis in Colorectal Cancer Cells. 2016 Int J Mol Sci pmid:27089328
Chun J et al. Alantolactone suppresses inducible nitric oxide synthase and cyclooxygenase-2 expression by down-regulating NF-κB, MAPK and AP-1 via the MyD88 signaling pathway in LPS-activated RAW 264.7 cells. 2012 Int. Immunopharmacol. pmid:22940184