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In vitro and in vivo studies on antitumor effects of gossypol on human stomach adenocarcinoma (AGS) cell line and MNNG induced experimental gastric cancer. |
2011 |
Biochem. Biophys. Res. Commun. |
pmid:21782799
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Yin J et al. |
Novel O-glycosidic gossypol isomers and their bioactivities. |
2011 |
Carbohydr. Res. |
pmid:21788013
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Ouyang DY et al. |
Valproic acid synergistically enhances the cytotoxicity of gossypol in DU145 prostate cancer cells: an iTRTAQ-based quantitative proteomic analysis. |
2011 |
J Proteomics |
pmid:21726675
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Le TT et al. |
Evidence for a trianion intermediate in the metalation of 4-hydroxy-6,7-dimethoxy-8-methyl-2-naphthoic acid. Methodology and application to racemic 5,5'-didesisopropyl-5,5'-dialkylapogossypol derivatives. |
2011 |
J. Org. Chem. |
pmid:21174400
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Hu ZY et al. |
Apogossypolone targets mitochondria and light enhances its anticancer activity by stimulating generation of singlet oxygen and reactive oxygen species. |
2011 |
Chin J Cancer |
pmid:21192843
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Baggstrom MQ et al. |
A phase II study of AT-101 (Gossypol) in chemotherapy-sensitive recurrent extensive-stage small cell lung cancer. |
2011 |
J Thorac Oncol |
pmid:21918390
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Akagunduz O et al. |
Radiosensitization of hormone-refractory prostate cancer cells by gossypol treatment. |
2010 Oct-Dec |
J BUON |
pmid:21229643
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Tiliabaev KZ et al. |
[Synthesis, structures, and acute toxicity of gossypol nonsymmetrical aldehyde derivatives]. |
2010 May-Jun |
Bioorg. Khim. |
pmid:20644599
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Modulation of apoptosis by natural products for cancer therapy. |
2010 |
Planta Med. |
pmid:20486070
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Ionov M et al. |
The interaction of PVP complexes of gossypol and its derivatives with an artificial membrane lipid matrix. |
2010 |
Cell. Mol. Biol. Lett. |
pmid:19936629
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Blevins S et al. |
Effects of silymarin on gossypol toxicosis in divergent lines of chickens. |
2010 |
Poult. Sci. |
pmid:20709972
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Yan F et al. |
A novel water-soluble gossypol derivative increases chemotherapeutic sensitivity and promotes growth inhibition in colon cancer. |
2010 |
J. Med. Chem. |
pmid:20684596
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Wu G et al. |
Responses of three successive generations of beet armyworm, Spodoptera exigua, fed exclusively on different levels of gossypol in cotton leaves. |
2010 |
J. Insect Sci. |
pmid:21067414
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Wei J et al. |
Synthesis and biological evaluation of Apogossypolone derivatives as pan-active inhibitors of antiapoptotic B-cell lymphoma/leukemia-2 (Bcl-2) family proteins. |
2010 |
J. Med. Chem. |
pmid:21033669
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ZHU Y et al. |
Involvement of Bcl-2, Src, and ERα in gossypol-mediated growth inhibition and apoptosis in human uterine leiomyoma and myometrial cells. |
2010 |
Acta Pharmacol. Sin. |
pmid:21102482
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Moretti L et al. |
AT-101, a pan-Bcl-2 inhibitor, leads to radiosensitization of non-small cell lung cancer. |
2010 |
J Thorac Oncol |
pmid:20354451
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Le A et al. |
Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression. |
2010 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:20133848
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Zhang XQ et al. |
Inhibition of proliferation of prostate cancer cell line, PC-3, in vitro and in vivo using (-)-gossypol. |
2010 |
Asian J. Androl. |
pmid:20081872
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Liu YX |
Temperature control of spermatogenesis and prospect of male contraception. |
2010 |
Front Biosci (Schol Ed) |
pmid:20036980
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El-Sharaky AS et al. |
Spermatotoxicity, biochemical changes and histological alteration induced by gossypol in testicular and hepatic tissues of male rats. |
2010 |
Food Chem. Toxicol. |
pmid:20832445
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