Woolley RJ |
Contraception--a look forward, Part II: Mifepristone and gossypol. |
1991 Mar-Apr |
J Am Board Fam Pract |
pmid:1823560
|
Tang G et al. |
Acylpyrogallols as inhibitors of antiapoptotic Bcl-2 proteins. |
2008 |
J. Med. Chem. |
pmid:18237106
|
RodrÃguez-EnrÃquez S et al. |
Energy metabolism transition in multi-cellular human tumor spheroids. |
2008 |
J. Cell. Physiol. |
pmid:18264981
|
Arnold AA et al. |
Preclinical studies of Apogossypolone: a new nonpeptidic pan small-molecule inhibitor of Bcl-2, Bcl-XL and Mcl-1 proteins in Follicular Small Cleaved Cell Lymphoma model. |
2008 |
Mol. Cancer |
pmid:18275607
|
Sprogøe K et al. |
Combining HPLC-PDA-MS-SPE-NMR with circular dichroism for complete natural product characterization in crude extracts: levorotatory gossypol in Thespesia danis. |
2008 |
J. Nat. Prod. |
pmid:18290629
|
Paoluzzi L et al. |
Targeting Bcl-2 family members with the BH3 mimetic AT-101 markedly enhances the therapeutic effects of chemotherapeutic agents in in vitro and in vivo models of B-cell lymphoma. |
2008 |
Blood |
pmid:18292288
|
Zha SW et al. |
[Male antifertility drugs and cell apoptosis]. |
2008 |
Zhonghua Nan Ke Xue |
pmid:18297819
|
Moon DO et al. |
Gossypol suppresses NF-kappaB activity and NF-kappaB-related gene expression in human leukemia U937 cells. |
2008 |
Cancer Lett. |
pmid:18314260
|
Mazumder B et al. |
Effect of chlorpromazine and gossypol on Ca(2+)-ATPase activity in the microsomal membranes of rat testes. |
1991 |
Indian J. Biochem. Biophys. |
pmid:1831790
|
Przybylski P et al. |
CP/MAS spectroscopy in the determination of the tautomeric forms of gossypol, its Schiff bases and hydrazones in the solid state. |
2008 |
Magn Reson Chem |
pmid:18338327
|
Kline MP et al. |
R-(-)-gossypol (AT-101) activates programmed cell death in multiple myeloma cells. |
2008 |
Exp. Hematol. |
pmid:18346839
|
Gao F et al. |
Interactive effects of elevated CO2 and cotton cultivar on tri-trophic interaction of Gossypium hirsutum, Aphis gossyppii, and Propylaea japonica. |
2008 |
Environ. Entomol. |
pmid:18348793
|
Sikora MJ et al. |
Anti-oxidant treatment enhances anti-tumor cytotoxicity of (-)-gossypol. |
2008 |
Cancer Biol. Ther. |
pmid:18376141
|
Dowd MK and Pelitire SM |
HPLC preparation of the chiral forms of 6-methoxy-gossypol and 6,6'-dimethoxy-gossypol. |
2008 |
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. |
pmid:18407810
|
Lv G et al. |
[The effect of gossypol, praziquantel and artemether on recombinant lactate dehydrogenase from Schistosoma japonicum]. |
2007 |
Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi |
pmid:18441994
|
Lu H and Liu GT |
Effect of dibenzo[a,c]cyclooctene lignans isolated from Fructus schizandrae on lipid peroxidation and anti-oxidative enzyme activity. |
1991 |
Chem. Biol. Interact. |
pmid:1849050
|
Wang X et al. |
Bioactivities of gossypol, 6-methoxygossypol, and 6,6'-dimethoxygossypol. |
2008 |
J. Agric. Food Chem. |
pmid:18517219
|
Johnson PW |
New targets for lymphoma treatment. |
2008 |
Ann. Oncol. |
pmid:18519406
|
Messiha FS |
Behavioral and metabolic interaction between gossypol and ethanol. |
1991 |
Toxicol. Lett. |
pmid:1853362
|
Boonsri S et al. |
Cytotoxic and antibacterial sesquiterpenes from Thespesia populnea. |
2008 |
J. Nat. Prod. |
pmid:18553924
|
Balakrishnan K et al. |
Gossypol, a BH3 mimetic, induces apoptosis in chronic lymphocytic leukemia cells. |
2008 |
Blood |
pmid:18566329
|
Politzer WM |
Long-term clinical remission of a patient with chronic lymphocytic leukemia using alternative treatment option: cottonseed oil (gossypol). |
2008 |
Phytomedicine |
pmid:18573644
|
Trischitta F and Faggio C |
Gossypol affects ion transport in the isolated intestine of the seawater adapted eel, Anguilla anguilla. |
2008 |
Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. |
pmid:18606239
|
Marzo I and Naval J |
Bcl-2 family members as molecular targets in cancer therapy. |
2008 |
Biochem. Pharmacol. |
pmid:18638457
|
Liu J et al. |
Stereoselective coupling of hemigossypol to form (+)-gossypol in moco cotton is mediated by a dirigent protein. |
2008 |
Phytochemistry |
pmid:18639908
|
Meng Y et al. |
Natural BH3 mimetic (-)-gossypol chemosensitizes human prostate cancer via Bcl-xL inhibition accompanied by increase of Puma and Noxa. |
2008 |
Mol. Cancer Ther. |
pmid:18645028
|
Villaseñor M et al. |
Gossypol disrupts embryo development in heifers. |
2008 |
J. Dairy Sci. |
pmid:18650278
|
Pankajakshy A and Madambath I |
Spermatotoxic effects of Cananga odorata (Lam): a comparison with gossypol. |
2009 |
Fertil. Steril. |
pmid:18692834
|
Przybylski P et al. |
Molecular structures and stability constants of gossypol and its aza-derivative complexes with silver(I) cations studied by potentiometric, ESI MS, NMR, and AM1d semiempirical methods. |
2008 |
J Phys Chem A |
pmid:18698745
|
Zhou DR et al. |
Gossypol repressed the gap junctional intercellular communication between Sertoli cells by decreasing the expression of Connexin43. |
2008 |
Toxicol In Vitro |
pmid:18706992
|
Benz CC et al. |
Gossypol effects on endothelial cells and tumor blood flow. |
1991 |
Life Sci. |
pmid:1875793
|
Etxebarria A et al. |
Regulation of antiapoptotic MCL-1 function by gossypol: mechanistic insights from in vitro reconstituted systems. |
2008 |
Biochem. Pharmacol. |
pmid:18762177
|
Azmi AS and Mohammad RM |
Non-peptidic small molecule inhibitors against Bcl-2 for cancer therapy. |
2009 |
J. Cell. Physiol. |
pmid:18767026
|
Sun Y et al. |
Apogossypolone, a nonpeptidic small molecule inhibitor targeting Bcl-2 family proteins, effectively inhibits growth of diffuse large cell lymphoma cells in vitro and in vivo. |
2008 |
Cancer Biol. Ther. |
pmid:18769131
|
Moon DO et al. |
Gossypol suppresses telomerase activity in human leukemia cells via regulating hTERT. |
2008 |
FEBS Lett. |
pmid:18775705
|
Wei J et al. |
Synthesis and evaluation of Apogossypol atropisomers as potential Bcl-xL antagonists. |
2009 |
Cancer Lett. |
pmid:18782651
|
Aoyama K |
[Determination of gossypol in feeds by HPLC]. |
2008 |
Shokuhin Eiseigaku Zasshi |
pmid:18787315
|
Tang Y et al. |
[Progress in small-molecule inhibitors of Bcl-2 family proteins]. |
2008 |
Yao Xue Xue Bao |
pmid:18819468
|
Sun J et al. |
ApoG2 inhibits antiapoptotic Bcl-2 family proteins and induces mitochondria-dependent apoptosis in human lymphoma U937 cells. |
2008 |
Anticancer Drugs |
pmid:18827561
|
Balakrishnan K et al. |
AT-101 induces apoptosis in CLL B cells and overcomes stromal cell-mediated Mcl-1 induction and drug resistance. |
2009 |
Blood |
pmid:18836097
|
Macoska JA et al. |
-(-)Gossypol promotes the apoptosis of bladder cancer cells in vitro. |
2008 Nov-Dec |
Pharmacol. Res. |
pmid:18840529
|
Janssen CO et al. |
Interaction of kendomycin and semi-synthetic analogues with the anti-apoptotic protein Bcl-xl. |
2008 |
Bioorg. Med. Chem. Lett. |
pmid:18845435
|
Sang GW et al. |
Inhibitory effects of gossypol on corticosteroid 11-beta-hydroxysteroid dehydrogenase from guinea pig kidney: a possible mechanism for causing hypokalemia. |
1991 |
J. Steroid Biochem. Mol. Biol. |
pmid:1888675
|
Gong YZ et al. |
Cinnamyl-3,4-dihydroxy-alpha-cyanocinnamate and nordihydroguaiaretic acid inhibit human Kv1.5 currents independently of lipoxygenase. |
2008 |
Eur. J. Pharmacol. |
pmid:18930721
|
Mi JX et al. |
Synergistic antitumoral activity and induction of apoptosis by novel pan Bcl-2 proteins inhibitor apogossypolone with adriamycin in human hepatocellular carcinoma. |
2008 |
Acta Pharmacol. Sin. |
pmid:19026166
|
Zhai G et al. |
A liposomal delivery vehicle for the anticancer agent gossypol. |
2008 Sep-Oct |
Anticancer Res. |
pmid:19035313
|
Stipanovic RD et al. |
Effect of racemic, (+)- and (-)-gossypol on survival and development of Heliothis virescens larvae. |
2008 |
Environ. Entomol. |
pmid:19036185
|
Chadha S et al. |
Alterations and reversibility of the effects of gossypol acetic acid on the intestinal uptake of end product nutrients in normal and protein calorie-malnourished male rats. |
1991 |
Ann. Nutr. Metab. |
pmid:1905512
|
Moore SA et al. |
Brain microvessel 12-hydroxyeicosatetraenoic acid is the (S) enantiomer and is lipoxygenase derived. |
1991 |
J. Neurochem. |
pmid:1907312
|
Kilic A et al. |
Efficacy of signal pathway inhibitors alone and in combination with Cisplatin varies between human non-small cell lung cancer lines. |
2009 |
J. Surg. Res. |
pmid:19084241
|