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The novel BH-3 mimetic apogossypolone induces Beclin-1- and ROS-mediated autophagy in human hepatocellular carcinoma [corrected] cells. |
2013 |
Cell Death Dis |
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Ni Z et al. |
Natural Bcl-2 inhibitor (-)- gossypol induces protective autophagy via reactive oxygen species-high mobility group box 1 pathway in Burkitt lymphoma. |
2013 |
Leuk. Lymphoma |
pmid:23398207
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Huo M et al. |
Suppression of LPS-induced inflammatory responses by gossypol in RAW 264.7 cells and mouse models. |
2013 |
Int. Immunopharmacol. |
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Goff DJ et al. |
A Pan-BCL2 inhibitor renders bone-marrow-resident human leukemia stem cells sensitive to tyrosine kinase inhibition. |
2013 |
Cell Stem Cell |
pmid:23333150
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Anderson MA et al. |
BH3 mimetic therapy: an emerging and promising approach to treating chronic lymphocytic leukemia. |
2013 |
Leuk. Lymphoma |
pmid:23339446
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Kannan A et al. |
Effect of feeding of calcium hydroxide-treated or vitamin E-supplemented cottonseed meal on plasma gossypol levels, blood parameters, and performance of Bikaneri lambs. |
2013 |
Trop Anim Health Prod |
pmid:23345064
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Ansari N et al. |
Quantitative 3D cell-based assay performed with cellular spheroids and fluorescence microscopy. |
2013 |
Methods Cell Biol. |
pmid:23317907
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Senarisoy M et al. |
Gossypol interferes with both type I and type II topoisomerase activities without generating strand breaks. |
2013 |
Cell Biochem. Biophys. |
pmid:23161103
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Hall C et al. |
Bcl-2 family of proteins as therapeutic targets in genitourinary neoplasms. |
2013 |
Clin Genitourin Cancer |
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Karaca B et al. |
Combination of AT-101/cisplatin overcomes chemoresistance by inducing apoptosis and modulating epigenetics in human ovarian cancer cells. |
2013 |
Mol. Biol. Rep. |
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Soderquist R et al. |
Gossypol overcomes stroma-mediated resistance to the BCL2 inhibitor ABT-737 in chronic lymphocytic leukemia cells ex vivo. |
2013 |
Leukemia |
pmid:23640104
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Granchi C et al. |
Small-molecule inhibitors of human LDH5. |
2013 |
Future Med Chem |
pmid:24175747
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Zhang Z et al. |
Fragment-based design, synthesis, and biological evaluation of N-substituted-5-(4-isopropylthiophenol)-2-hydroxynicotinamide derivatives as novel Mcl-1 inhibitors. |
2013 |
Eur J Med Chem |
pmid:23314054
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Zhong S et al. |
(-)-Gossypol-enriched cottonseed oil inhibits proliferation and adipogenesis of human breast pre-adipocytes. |
2013 |
Anticancer Res. |
pmid:23482766
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Varadarajan S et al. |
Sabutoclax (BI97C1) and BI112D1, putative inhibitors of MCL-1, induce mitochondrial fragmentation either upstream of or independent of apoptosis. |
2013 |
Neoplasia |
pmid:23633928
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Mazumder S et al. |
Mcl-1 Phosphorylation defines ABT-737 resistance that can be overcome by increased NOXA expression in leukemic B cells. |
2012 |
Cancer Res. |
pmid:22525702
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El-Mokadem MY et al. |
Alleviation of reproductive toxicity of gossypol using selenium supplementation in rams. |
2012 |
J. Anim. Sci. |
pmid:22585803
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Cheng W et al. |
[Effects of gossypol acetate on apoptosis in primary cultured cells from patients with lymphoid leukemia and its synergy with dexamethasone]. |
2012 |
Zhongguo Shi Yan Xue Ye Xue Za Zhi |
pmid:22541072
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Zhang YS et al. |
Gossypol exhibits a strong influence towards UDP-glucuronosyltransferase (UGT) 1A1, 1A9 and 2B7-mediated metabolism of xenobiotics and endogenous substances. |
2012 |
Molecules |
pmid:22543504
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Hsiao WT et al. |
Involvement of Smac, p53, and caspase pathways in induction of apoptosis by gossypol in human retinoblastoma cells. |
2012 |
Mol. Vis. |
pmid:22876131
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