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AT-101 induces apoptosis in CLL B cells and overcomes stromal cell-mediated Mcl-1 induction and drug resistance. |
2009 |
Blood |
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An open-label, multicenter, phase I/II study of single-agent AT-101 in men with castrate-resistant prostate cancer. |
2009 |
Clin. Cancer Res. |
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2009 |
Mol. Cancer Ther. |
pmid:19372563
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The immunosuppressive effect of gossypol in mice is mediated by inhibition of lymphocyte proliferation and by induction of cell apoptosis. |
2009 |
Acta Pharmacol. Sin. |
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Design and synthesis of a gossypol derivative with improved antitumor activities. |
2009 |
Arch. Pharm. (Weinheim) |
pmid:19340835
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Efficient production of gossypol from hairy root cultures of cotton (Gossypium hirsutum L.). |
2009 |
Curr Pharm Biotechnol |
pmid:19751178
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Targeting apoptosis in the hormone- and drug-resistant prostate cancer cell line, DU-145, by gossypol/zoledronic acid combination. |
2009 |
Cell Biol. Int. |
pmid:19716895
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Structure-activity relationship and molecular mechanisms of ethyl 2-amino-4-(2-ethoxy-2-oxoethyl)-6-phenyl-4h-chromene-3-carboxylate (sha 14-1) and its analogues. |
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J. Med. Chem. |
pmid:19743858
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ApoG2 induces cell cycle arrest of nasopharyngeal carcinoma cells by suppressing the c-Myc signaling pathway. |
2009 |
J Transl Med |
pmid:19698176
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Can gossypol be a hope for transsexual patients (male to female) before sex reassignment surgery? Just for adjusting the body to mind. |
2009 |
Med. Hypotheses |
pmid:19647947
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Mutual anti-oxidative effect of gossypol acetic acid and gossypol-iron complex on hepatic lipid peroxidation in male rats. |
2009 |
Food Chem. Toxicol. |
pmid:19665044
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The (+)- and (-)-gossypols potently inhibit both 3beta-hydroxysteroid dehydrogenase and 17beta-hydroxysteroid dehydrogenase 3 in human and rat testes. |
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J. Steroid Biochem. Mol. Biol. |
pmid:19429456
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Gossypol induced apoptosis of polymorphonuclear leukocytes and monocytes: involvement of mitochondrial pathway and reactive oxygen species. |
2009 |
Immunopharmacol Immunotoxicol |
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Gossypol, a polyphenolic aldehyde from cotton plant, interferes with swine granulosa cell function. |
2009 |
Domest. Anim. Endocrinol. |
pmid:19342192
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Gossypol--a polyphenolic compound from cotton plant. |
2009 |
Adv. Food Nutr. Res. |
pmid:19878861
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Combined gossypol and zoledronic acid treatment results in synergistic induction of cell death and regulates angiogenic molecules in ovarian cancer cells. |
2009 |
Eur. Cytokine Netw. |
pmid:19825521
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AT-101, a small molecule inhibitor of anti-apoptotic Bcl-2 family members, activates the SAPK/JNK pathway and enhances radiation-induced apoptosis. |
2009 |
Radiat Oncol |
pmid:19852810
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Mitogenic activity of zeranol in human breast cancer cells is enhanced by leptin and suppressed by gossypol. |
2009 |
Anticancer Res. |
pmid:20032412
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Cheng W et al. |
[Effect of gossypol acetate on proliferation and apoptosis in Raji lymphoblastoid cell line]. |
2009 |
Zhongguo Yi Xue Ke Xue Yuan Xue Bao |
pmid:19968063
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Endofacial competitive inhibition of the glucose transporter 1 activity by gossypol. |
2009 |
Am. J. Physiol., Cell Physiol. |
pmid:19386788
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